Methotrexate. Yokusetshenziswa

Medicine "Methotrexate" iyi-ejenti antitumor. I nomuthi kufakwe iqembu antimetabolites - folic acid abantu abamelene nani. Umkhiqizo "Methotrexate" ziphephile umsebenzi ngokumelene amaseli ekhula ngokushesha. Ngaphezu kwalokho, izidakamizwa uyakwazi kunethonya ezinye imiphumela immunosuppressive.

"Methotrexate". Yokusetshenziswa. Izinkomba.

Umuthi ezinqunyiwe acute wegazi lymph, Sarcoma Ewing sika, myagkokletochnoy futhi osteosarcoma, retinoblastoma, igciwane cell izimila esibelethweni kanye testis, isifo trophoblastic, medulloblastoma. "Methotrexate" Ukufundiswa ku isicelo uncoma ukusetshenziswa kanye nomdlavuza ngemomozi futhi wesibeletho, isikhumba, emphinjeni, ureter futhi kwezinso ukhalo, webele, iphaphu, izinso, isibindi, penile squamous ikhanda nentamo, kanye chlamydia. Umuthi kuboniswa ngenxa rheumatoid arthritis, i-psoriasis namafomu okunzima ukugeleza e engekho osetshenziswayo yi zokwelapha yokwelapha ezanele.

"Methotrexate". Yokusetshenziswa.

I nomuthi iwukuba emthanjeni, temlomo, intralyumbalnogo nokusetshenziswa esicutshini. I-batch luyabekezela ngamunye. Udokotela uyakucabangela isifo esithile, isimo kohlelo hematopoietic, wesifunda ukwelashwa antitumor.

Ukusebenzisa izidakamizwa Ingabangela sokuzincisha ukudla, stomatitis (izilonda emathunjini), gingivitis, isicanucanu, pharyngitis. Ezimweni ezingavamile, lapho enteritis, uhudo, pancreatitis, melena. Isikhathi eside engayitholi nsuku may kwezinye izimo imbangela ngokoma kwesibindi, necrosis kwesibindi, okunamafutha yoma, cystic kwesibindi periportal.

Esibi ukusabela nge ukusetshenziswa kwezidakamizwa "Methotrexate" imfundo manual libabiza kwegazi, leukopenia, isiyezi, ukukhathala, thrombocytopenia, aphasia, Ukudlikizela, ikhanda elibuhlungu, somnolence.

Kwezinye izimo kungase kube ukuphazamiseka nomjikelezo wokuya esikhathini, ukuphazamiseka spermatogenesis, oligospermia, ubuthakathaka, kwehle libido.

Ezinye iziguli cystitis, hematuria, kwezinso umsebenzi iziyaluyalu uhlamvu, kwehle ukumelana ukutheleleka, imfiva, urticaria, epidermal necrolysis anobuthi, photosensitivity, ukuqubuka, imihuzuko, induna, telangiectasia.

Contraindicated "Methotrexate" nge leukopenia, ukukhulelwa, iziyaluyalu kwesibindi nezinso libizwa. Akunconyelwe ithuluzi futhi immunodeficiency. Lapho udinga ukuthatha imithi ngesikhathi lactation, yokudla kufanele inqanyulwe. Ngenxa yalokho, ezinye izifundo sezisungule teratogenic futhi embryotoxic imiphumela.

Abesifazane yokuzala kufanele usebenzise zokuvimbela inzalo ethembekile uma kusetshenziselwa "methotrexate".

izidakamizwa anconyelwe isilonda peptic ku duodenum nasesiswini, effusion pleural, ascites, isifo sezinso, sifo, nesifo (izilonda emathunjini).

Iziguli upokisi okwamanje noma esanda kushintshwa, herpes (i-herpes) nezinye izifo ezithathelwanayo sibi "Methotrexate" ayizange inikezwe.

Ngaphambi ukwelashwa sisetshenziswa on isizinda yokwelapha edingekayo ukulawula igazi isithombe (neuropathy), umsebenzi izinso esibindini.

Ngo ukusetshenziswa "Methotrexate" I-rheumatoid arthritis noma psoriasis okungukuthi edingekayo ukuze afeze ezivamile kwegazi (enemininingwane) okungenani kanye ngenyanga, laboratory izifundo ukusebenza isibindi, izinso - okungenani kanye ngenyanga noma ezinyangeni ezimbili.

Ngaphambi aphoyintimenti isiguli kumele kube ujwayelene kuwukubonakaliswa enqabayo okusolwayo. "Methotrexate" kuyinto imithi sina. Ukuze ugweme ukuxakeka engadingeki ukusetshenziswa imithi kufanele ziqashwe ngudokotela.