I-Nicotinic acid (imijovo)

I-Nicotinic acid (imijovo) ibhekisela kuma agent athile e-anti-pellagra. Kulo xhumano, ukulungiswa kunesiqalo esithi "PP-vitamin". I-Nicotinic acid (imijovo) uma isetshenziselwa izigaba zokuqala ze-pellagra inomthelela ekuqedeni izenzakalo zayo.

Ngaphezu kwezinto zokulwa ne-pellagrafic, i-vitamin PP ithuthukisa umzimba we-carbohydrate metabolism, inomthelela omuhle ngesifo sikashukela emafomini, isifo senhliziyo, isibindi, isilonda se-peptic ku-duodenum nesisu kanye ne-enterocolitis. I-Nicotinic acid (imijovo) inesakhiwo se-vasodilating, iphinde ikhuthaze ukuphulukiswa kwamanxeba.

I-PP-vitamin ine-lipoproteinemic effect, ukunciphisa izinga le-lipoproteins egazini.

I-Nicotinic acid (imijovo) inomthelela ekwenzeni isimo sobuchopho nesimiso sezinzwa. Ngaphezu kwalokho, kunomphumela omuhle ohlelweni lwe-cardiovascular, ukugaya. I-Nicotinic acid esikhumbeni ingomunye wabasizi abakhulu ekulondolozeni esimweni esinempilo. Ngaphezu kwalokho, i-PP-vitamin iyasiza ukuqinisekisa umbono ovamile, ihileleka ekuthuthukiseni ukujikeleza kwegazi, ukunciphisa ukucindezelwa kwegazi eliphezulu ngenxa yezindawo zayo ze-vasodilating.

I-Nicotinic acid ye-lactation iyishukumisayo. I-Vitamin PP ihlanganyela ekugcwaliseni igazi kwegazi kanye nokusheshisa kwegazi ngegazi.

Isidakamizwa siyatholakala kuma-ampoules.

Nge-stroke ischemic, i-PP-vithamini ilawulwa ngaphakathi. Isilinganiso singu-milliliter eyodwa yesisombululo se-1%.

Ukuphatha okungahambi kahle kufanele kube kancane. Ukuphathwa okusheshayo kokuphathwa kwesisombululo kungaholela ekunciphiseni okukhulu kwegazi. Ukujova kwe-intramuscular and subcutaneous ye-nicotinic acid kubangela ubuhlungu.

Ukuthatha izidakamizwa ngaphakathi (ngesimo se-powder noma amaphilisi), ikakhulukazi, esiswini esingenalutho noma abantu abane-hypersensitivity, kungavusa ukuzondeka, ukubomvu kwengxenye engenhla ye-trunk nobuso, ukuzwakala kokugeleza kwamanzi kuya ekhanda, i-paresthesia (ukugwedla emaphethelweni), nokuqeda. Njengomkhuba wokubonisa, lezi zibonakaliso ziqedwa ngokuzimela ngemva kwesikhathi esithile.

Ngokungahambi kahle izidakamizwa ziphikisana nabantu abanezifo eziphakeme kakhulu ezifweni (ikakhulukazi ukwanda okuqhubekayo kwegazi) kanye ne-atherosclerosis.

Uma kukhona ukuzwela okwandisiwe ku-nicotinic acid, isidakamizwa sinconywa ukuba sithathelwe indawo yi-nicotinamide. Okuhlukile kungase kube ukusetshenziswa kwezidakamizwa njenge- vasodilator.

Ukuze ukwandise i-lactation, lesi sidakamizwa senziwa ama-milligram amahlanu ngamazwi ngomlomo kathathu ngosuku imizuzu eyishumi kuya kwemihlanu ngaphambi kokuncelisa.

Ukuqokwa kwamakhemikhali kunesidingo ukuxwayisa isiguli mayelana nokusabela okungenzeka komlingiswa wesikhathi esifushane (ukuvuvukala ebusweni nasengxenyeni ephezulu yomzimba, ukuzwa ukugcwaliswa kwezigulane ezincelisayo, ezimweni ezingavamile ukuhlushwa). Inhloso ye-nicotinic acid inconywa ngokuhambisana ne-ascorbic acid.

Kumele kuqashelwe ukuthi ukudla isikhathi eside kwevithamini-PP emithini emikhulu kungadala ukuthuthukiswa kwesibindi samafutha. Ukuze uvimbele le nkimbinkimbi, kubalulekile ukufaka phakathi kokudla okucebile ku-methionine (i-amino acid engakhiwe emzimbeni) imikhiqizo noma ukubeka imithi ye-methionine nezinye i-lipotropic (ukusebenzisana ngamafutha) ngokukhethekile.

I-Nicotinic acid ifakwe emalungiselelweni afana ne-Vitayodourol, i-Xanthinal Nicotinat, i-Vicine, iNikoverin, i-Lipostabil, i-Spasmocor, i-Nikospan, nabanye.

Isidakamizwa kufanele sinikezwe kuphela ngaphansi kokuqondiswa kochwepheshe.