Bilirubin Direct aphakeme - kusho ukuthini? bilirubin Direct: evamile

Akuwona wonke umuntu ngokuphelele uyazi anatomy zomzimba wakho nokuqina, izakhi elihlukahlukeneko elingaphakathi. Ngenxa yalesi sizathu, ngemva kokuthola imiphumela yokuhlolwa, ngezinye izikhathi nokukhathazeka owengeziwe. Phela, asikwazi ukuchaza noma ukuqonda ezinye zezimiso, futhi ngenxa yalokho, alikho amandla ethu ukuhlola isimo sabo kahle. Enye yalezi amagugu isithekile bilirubin esiphakeme igazi. Izimbangela kanye nokwelashwa, kanye izimpawu zalesi simo zizohlolwa ngezansi.

Bilirubin - izidakamizwa emzimbeni womuntu

Le into organic imiswe phakathi neminyaka kwamazinyo engokwemvelo-hemoglobin ngenxa ukubhujiswa abomvu egazi ashaye - amangqamuzana abomvu egazi. Le nqubo kwenzeka ngokuqhubekayo njengoba kokuphela inkonzo impilo erythrocyte. Bilirubin kungabonakala igazi noma uketshezi olungenambala olusegazini Bile. khona okungavamile bilirubin e ketshezi ngokuvamile ubonisa khona izimo igazi normal (Ukubhujiswa ngokweqile amangqamuzana abomvu egazi), ipheshana hepatic noma biliary.

bilirubin oqondile Ngokungafani nezinye izinhlobo

Kwezesayensi yezokwelapha, kukhona izinhlobo ezimbili bilirubin - nenkhulumombiko. Umyalo wesibili lezi, ngokuthi ngisho engahlobene kwakheka amaseli isibindi (80%), kanye nalo lonke - e ubende kanye umnkantsha amaseli.

bilirubin okuqondile, ngokuthi lesibopho, kwakheka isibindi ngokuhlanganisa engaqondile bilirubin glucuronic acid. Lokhu kuyadingeka ukuqinisekisa ukuthi into enobuthi futhi zingaxazululeki sashintshwa saba ifomu encibilikayo futhi ngempumelelo unekhemikhali Bile.

Nokho, okungezona ezinobuthi futhi kalula encibilikayo bilirubin conjugated nalo imiphumela eyingozi emzimbeni. Ngezinye lokuhlala ephakeme we ketshezi Bile ekuthanda kwezulu kanye crystallization, lokhu kungase luholele kumiswa ezifakwa siqinile timphawu tesakhiwo we gallbladder futhi Amapayipi yayo.

Imiphumela ukuhlolwa laboratory avamise ukubizwa bilirubin inani, kodwa igama lwasemtholampilo, emzimbeni we indaba akuyona. Ngaphansi lo mqondo eyenani ingqikithi bilirubin nenkhulumombiko.

Kungani inikwe ukuhlolwa igazi for bilirubin oqondile?

Lolu cwaningo kubalulekile ngoba ikuvumela ukuba uphendule umbuzo bilirubin anda ngenxa kokusebenza kwesibindi ukungakhuli noma cha. Yandisa ka bilirubin ngenxa amazinga aphezulu engaqondile kungenzeka kuphela ngokwandisa ukuhlukaniswa elithwala umoya-mpilo. Ukwenyuka kuphela izidakamizwa kalula encibilikayo kuvamile kakhulu outflow Bile basebenzile zakhekile, ezifana ukuvaleka mechanical of the Amapayipi Bile.

Izizathu nesanda bilirubin egazini lihlukile. Kuyinto evamile sina isifo ngokukhukhumala kwentamo isibindi - Hepatitis. Lesi sifo libhekene iqiniso lokuthi emangqamuzaneni omzimba abakwazi ukuhoxisa isilinganiso esifanele sombala ku gallbladder futhi Amapayipi yayo. Isikhathi esijwayelekile ukuziphatha igazi test bilirubin direct ukuhlonza isifo futhi ukuvimbela inchubekelembili wayo.

Kuyini izinga legazi bilirubin?

Ukuze ukwazi ukubona ngokunembile isimo sokugembula, ochwepheshe wasungula umqondo bilirubin kuyinsakavukela egazini. Kungase ngamunye ayahlukahluka, kodwa okweqa kulokhu amagugu kungase kubonise nokuphazamiseka kwempilo sina.

Ngo ithebula singabona ukuthi eyehlukene izinga ezahlukene bilirubin egazini. Xaxa bilirubin, izimpawu, impatho kunqunywa kuphela nguchwepheshe, kungaba ukwenzeka ngezinsuku zokuqala ngemva kokuzalwa. Ngakho-ke kubalulekile ukuqapha ezingeni layo egazini, ngakho miss zokugula ezibucayi kwezitho zangaphakathi.

Uma kukhona zokugula nokwanda bilirubin oqondile?

sombala Ukwandiswa lokuhlushwa kungenzeka kwakhiwa uma kakhulu, noma kunezithiyo excretion yayo.

Iningi ukukhiqizwa okweqa bilirubin siyenzeka yezifo ezihlukahlukene ngofuzo, futhi hhayi kuphela isibindi, kodwa futhi we hematopoiesis. Ukuze lokhu kungabangela ezihlukahlukene kwegazi, ngokuyinhloko walandisa fragility anda kwamangqamuzana egazi abomvu, kanye zokugula we ubende, ngokweqile kokubhubhisa namangqamuzana abomvu egazi, kuhlanganise nabathandekayo enempilo.

Ubunzima ushintsho futhi kukhuthaza ka bilirubin ngokuvamile uhlanganiswa isifo sesibindi, okwenzeka ngenxa yokulimala owadalwa ubuthi noma okuvela inflammations. Ngokuvamile, lokhu kunikeza isithombe isifo gallstone nezinguquko umdlavuza.

Izizathu ukuthi kwaholela ekwandeni e bilirubin amazinga e cwaningo zihlukaniswe amaqembu amabili amakhulu: Isibindi kanye Extrahepatic. Eyokuqala okuvame ukubangelwa izinqubo diffusive esibindini, kanti eyesibili - ne isibazi noma nezinye izifo mechanical inqubo Bile outflow.

izimbangela Hepatic:

• Acute viral nokohlobo A, B, C.
• ukusha kwesibindi kohlobo Okungalapheki futhi webhaktheriya (i brucellosis, leptospirosis).
• ukusha kwesibindi kohlobo Toxic, kubangelwa isenzo izidakamizwa okubalwa.
• cholestasis Intrahepatic.
• Oncological isifo sesibindi.

izimbangela Extrahepatic:

• Kokucindezela we Amapayipi Bile.
• Izifo zithuthwa.

Ngakho, amazinga aphakeme bilirubin oqondile zingase zibe Indlela kwempilo emzimbeni futhi awukwazi kumelwe ibe isisekelo sokukholelwa i ukusazi ngokunembile isifo esikuphethe. Kodwa ngokwazi amaphuzu, ungakwazi nokuziphatha okwengeziwe okubhekiswe ukuhlola isiguli.

Khulisa bilirubin olukhululekile egazini

Uma imiphumela yokuhlolwa ukukhombisa izinga sombala engaqondile ephakeme, kubalulekile ukuba sinake CBC, okungukuthi, inani abomvu egazi ashaye futhi athwala umoya-mpilo. Kusukela bilirubin engaqondile washintsha ngenxa ukuwohloka anda elithwala umoya-mpilo abantu kuyoba izimpawu ezisobala igazi. Ngenxa ekuqongeleleni igazi e sombala olukhululekile futhi iyakhula izici ngokweqile avele anaemia hemolytic (by-jaundice).

Izimbangela bilirubin ongaphakeme

Enye yezimbangela ehamba phambili nokwehlisa bilirubin eqondile senhliziyo. Futhi, lesi simanga kwenzeka ngemva kokuthatha utshwala, i-caffeine (kuhlanganise iziphuzo energy) nezidakamizwa ezithile (penicillin akuzange kusize, prednisone nabanye).

Njengoba nibonakala owabonakaliswa bilirubin zandiswe igazi?

Uma bilirubin oqondile liphakeme, kusho ukuthini? Ngezinye lokuhlushwa eliphezulu bilirubin oqondile egazini iziguli uhlangabezana yellowing we sclera, futhi ezimweni ezimbi kakhulu futhi isikhumba. Umchamo kuba elihlale umbala ophuzi kanye endleni, discolors ephambene ngenxa excretion kahle ngokusebenzisa sombala emathunjini. On udokotela kungathola uphawu noma isibindi lakhulisiwe, ubuhlungu kungenzeka e projection we gallbladder.

Uma bilirubin oqondile liphakeme, kusho ukuthini lokho iziguli acute ukusha kwesibindi kohlobo viral? Kulokhu, lo muntu angase esekhala ukungakuthandi ukudla, isicanucanu, ukusinda kanye nobuhlungu hypochondrium kwesokudla.

Lapho kufushane outflow ka Bile kukhona ushintsho ibala lesikhumba. Lokhu kungenxa yokuthi i-bilirubin ngokusebenzisa amathumbu kungukuthi kokuphuma, kodwa wabe esebuyela kwi egazini oyihlungile ngu nezinso. Ngaphezu izimpawu "jaundice", ongabonisa ngokucacile izimpawu zesifo ezibangele kokunikezwa kwe-outflow ka Bile. Lokhu izimpawu ka-acute, pancreatitis okungamahlalakhona, cholelithiasis , kanjalonjalo. Izindlela ephumelela kunazo diagnostrovaniya isifo ngezikhathi ezinjalo kukhona tomography noma ultrasound. Asiza ukuhlonza ukuvuvukala sokuvuvukala ezindongeni Amapayipi Bile, kanye kokuncishiswa izimila ezehlukene.

Bilirubin ebantwaneni ngezinsuku zokuqala zokuphila

Umzimba izinsana Kuthi sihlukile abadala. Ekuzalweni kukhona i-hemoglobin okuqukethwe high blood tesifundvo fetus ukuba nokucekelwa okusheshayo futhi kukhuthaza kusuka emzimbeni. Ngakho-ke, ezinsukwini zokuqala zokuphila ngokuvamile kakhulu waphawula bokuphila, jaundice zemvelo. Kodwa njengoba kumiswa isibindi uhlelo enzyme ithatha bilirubin engaqondile emgceni locondzile, lezi zibonakaliso uhambe ngokushesha.

Nokho, kukhona amathuba lapho ivela khona futhi sokugembula jaundice ngayo lapho usana. It kungadalwa izinqubo ezifana:

• akuhambisani iqembu igazi RH isici zikamama nomntwana;
• fragility lezinceku erythrocyte, elibangela ukukhiqizwa lelitfutfukile bilirubin engaqondile;
• ukusha kwesibindi kohlobo samafayela;
• ukwephulwa outflow ka Bile kusukela kwesibindi nezinye imvelo lokukhanda.

Ukwelashwa nokuvikelwa bilirubin esiphakeme igazi

Kuthiwani uma bilirubin liphakeme, akunakwenzeka ukusho ngokuqiniseka. Izenzo ancike ezicini eziningana. Okokuqala udinga ukukhomba uhlobo lesi sifo, kungani kwaphakama ke. Izizathu nesanda bilirubin egazini kuhluka uphethwe kanye nokwelashwa ukuqokwa udokotela angeke esekelwe idatha kusuka izifundo eyodwa noma ezimbili. izifundo engeziwe ingase yabelwe: ultrasound, ngekhompyutha tomography, okuvumela ukuba embule khona imali okuqinile noma ezinye obstructions ukugeleza Bile, ngenxa okuyinto kukhona bilirubin zandiswe igazi. Izimbangela, impatho yale nqubo isifo unganquma kwezinye izimo, eyisazi (isifo igazi Uchwepheshe), kwabanye - nezifo ezithathelwanayo. Uma ubhekana nezinkinga outflow ka Bile babelwe yokwelapha okuhloswe ngaso ukususwa zibe we Amapayipi Bile futhi nenyongo sesinye.

Namkha kunjalo, njengawo izinto eziningi emzimbeni, bilirubin akufanele kuthathwe ngokuthi slag ezingenamsebenzi ngokuphelele. Njengoba kuboniswa ucwaningo lwamuva, bilirubin kuyinto antioxidant omuhle kakhulu, baphakame kahle vitamin E. It uyakwazi okunqanda compounds peroxide, ekuvimbeleni ukukhumuzeka izimo eziningi sokugembula nezifo. Ngakho, abantu ngegazi okusezingeni eliphezulu bilirubin ingozi atherosclerotic izilonda semithambo kanye ezihlobene nesifo senhliziyo is kakhulu ziyancipha. Bilirubin ikwazi ukulwa ne nolaka free radicals, kunciphise ingozi yomdlavuza.

Izici bilirubin abesifazane abakhulelwe

Ngezinye izikhathi kuyenzeka ukuthi bilirubin oqondile liphakeme kwabesifazane abakhulelwe. Kusho ukuthini lokhu ngabo? State yokukhulelwa ayikwazi ukuyithukuthelisa ukwehla noma ukwanda yalolu ketshezi. Ngokuvamile, omama abakhulelwe baye baphawula ukuthi imiphumela ukuhlaziywa izinto eziyisethenjwa Inkomba oluhambisana kukholamu "Bilirubin umthetho oqondile". Anyusiwe, zehliswa ezikhundleni, kungenzeka ngenxa yokukhulelwa, futhi ngesikhathi exacerbation izifo ezingelapheki noma ukubukeka pathologies entsha. Isigqugquzeli igazi sombala okuqukethwe kungahle kwabangela izifo ezifana cholestasis, anaemia hemolytic, isifo sokusha kwesibindi, cholecystitis. Izimo ezinjalo zidinga luhlolo ngokushesha futhi ephelele abesifazane, futhi ngaleso sikhathi udokotela ekunika i ukwelashwa okufanele futhi ngempumelelo.

Izindlela wehlise bilirubin

Uma uzithola izimpawu anda bilirubin oqondile, kubalulekile ukuba balahle kubo, njengoba isimo ezinjalo kungathonya isimo izitho zangaphakathi. Ukuze wehlise izinga sombala kumele siqale sihlole indlela odla ngayo. Imiphumela Ubuhle bungatholakala ngokushintsha Ukudla. Ukuze wenze lokhu:

• ayeke ukudla ukudla okuthosiwe nokudla okunongwe kakhulu;
• ayifakiwe ngokuphelele kusukela ekudleni uphuzo oludakayo;
• ungasebenzisi kule iziphuzo ukudla amagesi;
• Kiddies olusanda kuzalwa kudingeka baphuze uketshezi ngokwengeziwe ukususa ngokushesha ubuthi emzimbeni.

Kuyadingeka ukuba azinake isimo isibindi. Ukusebenzisa le mithetho elula ukunikezela, uvumela lolu umzimba ukuhlanza bese alulame. A isibindi enempilo ngenkuthalo ukususa semali bilirubin ku Bile futhi igazi. Ngaphezu kwalokho, kubalulekile ukuba balandele umsebenzi okunempilo emathunjini. ukudla ebilisiwe wabhaka ikhuthaza umsebenzi omuhle emathunjini. Awukwazi ucede ngokwayo ne ukudla engapheli noma indlala, kuholela ukungasebenzi ngokweqile, izitho zokugaya.

Ngakho, kuphela uphawu yisimo lapho bilirubin oqondile luyanda. Kusho ukuthini? Lokhu kusikisela ukuthi kubalulekile ukuba umane inciphise sombala egazini, kodwa futhi welaphe imbangela.

izinqubo sokugembula esibindini iyobonakaliswa ngokusebenzisa ukucanuzela kwenhliziyo, ubuhlungu kulomzimba, umuzwa wobukhulu, imfiva, ukunambitheka ababayo emlonyeni. Uma anaemia kungenxa bilirubin anda, kuyoba ukuzibonakalisa ngokusebenzisa imibala yellow nolwelwesi lwamafinyila, ukukhathala okungamahlalakhona, ukushaya kwenhliziyo njalo, ubuhlungu lwesokunxele esifubeni. Iyokhushulwa bilirubin ngenxa biliary ipheshana isifo, owabonakaliswa umchamo onombala, ukuphazamiseka esesuthi, ukulunywa ezinzima kanye nesicanucanu.

Ngaphansi kwalezi zimo kubalulekile ukuthatha ukuhlolwa igazi for bilirubin oqondile. Yiziphi imiphumela kanye neziphakamiso ukwehlisa ke - udokotela uthi.