Umuthi 'Vigantol ": yokusetshenziswa, analogs kanye nokubuyekeza

Kungani sidinga imithi enjalo, njengoba "Vigantol"? Yokusetshenziswa futhi analogue yalesi izidakamizwa izokwethulwa ngezansi. Futhi, sizokutshela ngayiphi indlela lokhu izidakamizwa luyatholakala, ukuthi kubiza malini, uma unalo yini imiphumela emibi kanye contraindications.

Ukwakheka, emaphaketheni, ijamo, incazelo

Siyini "Vigantol"? Yokusetshenziswa, exhunywe izidakamizwa, ukuthi izidakamizwa ulawula i-calcium ne phosphorus umzimba emzimbeni womuntu. Itholakala njengoba isixazululo kucace oily ngoba eyanele. I nomuthi uba nombala kancane aphuzi futhi ukungaguquguquki viscous.

1 ml izidakamizwa equkethwe 500 UG kolekaltsiferola nezinsizasenzo njengoba triglyceride srednetsepochnyh. Umuthi is ithunyelwa 10 ml izitsha eziyisikhombisa ezenziwe ngengilazi amnyama nokuba plug-weThrojani.

Pharmacodynamics nomuthi

Kanjani lesi sidakamizwa "Vigantol"? Yokusetshenziswa ubonisa ukuthi ekwakhiweni asebenzayo has a olawula calcium ne phosphorus umzimba isinyathelo kwemithi. Ngesikhathi esifanayo kwenza kuze nokushoda vitamin D _3, kwandisa calcium ukumuncwa e pheshana emathunjini nezinso reabsorbs zikasawoti.

Ngaphezu kwakho konke okungenhla, nomuthi "Vigantol" ikhuthaza ithambo ezilamatshe aligugu, okuyinto ebalulekile ukusebenza evamile nezindlala parathyroid.

I pharmacokinetics sedivayisi yezokwelapha

Lapho ukumuncwa senzeka "Vigantol" izidakamizwa? Yokusetshenziswa kusikisela ukuthi ukumuncwa izimali Kwenziwa kusukela ipheshana wokugaya ukudla. Ngaphakathi womuntu umzimba ejenti asebenzayo sibopha ukuthi α2-globulin kanye ezinye ingxenye - ne-albumin.

Kolekaltsiferol aqoqana isibindi, adipose kwezicubu amathambo, kanye kwemisipha lwamathambo, izinso, izindlala adrenal futhi myocardium.

Ukufinyelela emakamu eliphakeme isithako esisebenzayo emisipheni waphawula ngemva kwamahora angu-4-5. Ngemva kwalokho, ubizwa kancane, Nokho encishisiwe, isikhathi eside ke inakekelwa ezingeni oyifunayo ukuze bayothola ukwelashwa.

Ochwepheshe kwatholakala ukuthi Kolekaltsiferol ezikwazi ukuhlaba zingene placenta. Bathola nokuthi ketshezi ikhishwe kanye obisini lukamama, ngakho-ke is hhayi Kunconywa ukuba sisebenzise ngesikhathi lactation.

Ngenxa biotransformation e izinso futhi isibindi akhiwa metabolites alisebenzi futhi esebenzayo ezifana digidroksikolekaltsiferol, kaltsifediol futhi calcitriol.

Kuboniswa izidakamizwa nomzimba womuntu kanye Bile okuncane - kanye nomchamo.

Yini ukuyisebenzisa?

Manje uyazi ukuthi izakhiwo izidakamizwa "Vigantol". I izinkomba enkulu yalokhu zifo kwayo ukusetshenziswa:

• spazmofiliya;
• yamathambo;
• osteomalacia.

Uvala ukusetshenziswa kwezidakamizwa

Kungakhathaliseki ukuthi kukhona Izimo umuthi ezifana "Vigantol" (wentengo laloku lokubhalwe lapha ngentasi nje)? It is hhayi Kunconywa ukuthatha izindlela ngaphansi kwale mibandela elandelayo:

• hypercalcemia;
• anda kuvelana tincenye ekwakhiweni;
• hypercalciuria;
• sarcoidosis;
• khona ezinso (limestone);
• immobilization.

Indlela "Vigantol"? Izindlela kanye umthamo

Thatha izidakamizwa kufanele kubhekwe kuphela kadokotela. Futhi, ngaphambi kokusebenzisa kubalulekile ukufunda imiyalelo okuvalelwe ngokucophelela. It wabonisa ukuthi lesi sidakamizwa "Vigantol" osanda kuzalwa bebhincile ubisi lwebele noma iluphi olunye uketshezi. Ukuze lokhu isixazululo axutshwa ngesilinganiso esifanele ukudla umntwana spoon encane.

Ngokuba nokuvimbela izifo ezifana yamathambo, futhi bekujabulela eside izingane kusukela ezinyangeni ezimbili ebekiwe nsuku 1 iconsi ukulungiswa. Thatha le imithi izinsuku ezinhlanu. ukwenza ikhefu izinsuku ezimbili emva ngesikhathi esithile.

Izingane kusukela eminyakeni owodwa kuya kwemibili is hhayi Kunconywa ukunikeza imithi phakathi nezinyanga zasehlobo.

Ukuze izingane ngaphambi kwesikhathi ne izinsuku ezingu-10 zokuphila umthamo onqunyiwe 2 amathonsi (usuku ngalunye). Lokhu kwelashwa kufanele kuqhutshwe usuku lonke, okwenza ikhefu izinsuku ezimbili. Ngaphandle impatho enjalo futhi zasehlobo.

Njengoba for ekwelapheni yamathambo ukusebenzisa izidakamizwa "Vigantol"? Amaconsi kulokhu ukuthatha ebulilini. Ngokwesibonelo, izingane kusukela izinsuku ezingu-10 zokuphila avunyelwe nsuku ukunikeza ku 2-8 amathonsi.

"Vigantol" abadala nazo aqokwe udokotela ukuba khona. Oku-nesineke asitholayo ngihlolwa, phakathi kwesikhathi lapho izinga Kumiswa vitamin D ukuntula _H. By the way, ezingeni layo ngaso sonke isikhathi kufanele ziqashwe ngesikhathi sonke ekwelapheni.

Ukweqisa izidakamizwa imithi

Yiziphi izimpawu ukweqisa izidakamizwa zenzeka uma engafanele kokuthola izidakamizwa ezifana "Vigantol"? Analogs yalesi izidakamizwa kanye izidakamizwa ngokwayo ukuze kusetshenziswe umthamo owodwa, eye ebekwe udokotela ukuba khona.

Ngokuvamile lokhu kusho amacala ukweqisa izidakamizwa elihlobene ne yokuthi emzimbeni womuntu, okubalwa nengane, buthelela semali vitamin D _W. Kwenzeka hypervitaminosis D ₃ ngalesi isimo. Izimpawu zayo zihlanganisa ukuqunjelwa noma isifo sohudo, pollakiuria, ikhanda elibuhlungu, ukoma, ukuhlanza, ukudla, ukudla nocturia, isicanucanu, polyuria, ubuthakathaka jikelele, metallic ukunambitheka emlonyeni nokunye.

Ngaphezu kwalezi zimo, isiguli singase atfutfukise neziyaluyalu ngaphezulu ngendlela ithambo ubuhlungu, turbidity umchamo, umfutho wegazi ophakeme, pruritus, myalgia, hyperemia conjunctival, arrhythmia, njll

Ngaphansi kwalezi zimo yokwelapha izisulu iqondiswa ekuthuthukiseni hypercalcemia. Isikimu ekwelapheni isifo kuncike kobukhulu.

Ngakho, uma kwenzeka izimpawu overdosage izidakamizwa amankeyane, futhi isiguli ekunike Ukudla ongaphakeme-calcium, vitamin E, ukusetshenziswa esiningi uketshezi, ascorbic acid, thiamine, retinol, riboflavin futhi pantothenic acid.

Kepha Ezimweni ezimbi kakhulu, zidinga ekuphathweni emthanjeni of 0.9% sodium chloride solution, calcitonin, furosemide, electrolyte kanye hemodialysis.

Ukuze ugweme ukweqisa izidakamizwa kudingeka sihlale njalo siqaphele lokuhlushwa le-calcium egazini.

ukusabela ezingezinhle

Ngokuvamile, "Vigantol" amavithamini ibekezelelwe kahle impela. Ezimweni ezingavamile, isiguli singase ukuthuthukisa imiphumela elandelayo engathandeki:

• hypercalciuria;
• isicanucanu;
• hypercalcemia;
• arrhythmia;
• sebethule calcium ukubunjwa kwezicubu ezithambile;
• ukuhlanza;
• somzimba;
• ukwephulwa wengqondo ukwazi;
• urolithiasis;
• kwehle esesuthi, polyuria nokoma.

izidakamizwa ekuhlanganyeleni

Izidakamizwa "Vigantol" kungathinta edonsa nezinye izidakamizwa. Ngakho-ke, ngaphambi ukusebenzisa, qiniseka bonana nodokotela wakho futhi ufunde imiyalelo. By the way, zinyanga efakwe ohlwini izici ezilandelayo nomuthi:

• Ukusetshenziswa "phenytoin", kanye ejenti okuqondene barbiturates iqembu kwandisa izinga ukuguqulwa zokwakheka yandisa isidingo zomzimba womuntu uvithamini D _3.
• Inhlanganisela nomuthi "Vigantol" a bisphosphonate "calcitonin" futhi "plicamycin" lokuqala kunciphisa ukusebenza kahle. Kufanele kuphawulwe ukuthi "Colestipol" futhi "Kolestiramin" kuzinciphise ukumuncwa emathunjini ka amavithamini fat-encibilikayo. Leli qiniso kudinga ukwandisa umthamo wabo.
• ekuphathweni esisodwa zomuthi nge antacids eziqukethe aluminium kanye magnesium izinhlayiya (ikakhulukazi isikhathi eside), kungase ukwandisa lokuhlushwa zabo egazini, kanye ukugcina ingozi lokudakwa.
• Inhlanganisela vitamin D _3, analogue yayo noma metabolites. Nokho, lokhu kufanele kwenziwe kuphela ezimweni ezikhethekile. Kuyadingeka ukuba ngokuqinile ukulawula izinga le-calcium egazini.
• ukwelashwa Kuhlanganiswe ka glycosides inhliziyo ukwandisa ezingaba anobuthi zomuthi ngenxa hypercalcemia. Iziguli ezinjalo kudingeke aqhube ECG, kanye ukulawula ezingeni calcium ne ukulungiswa umthamo glycosides inhliziyo. Ingozi hypercalcaemia kungandisa benzodiazepine nemikhiqizo.
• ukusebenza encishisiwe imithi kubhekwe is ebonwe okuhambisanayo yokwelapha "isoniazid" futhi "rifampicin". Lokhu kungenxa yokuthi bayakwazi ukwandisa izinga biotransformation.
• Ochwepheshe wathola ukuthi isisu thiazide, i-calcium excretion kubambezela inqubo umchamo. ukuchayeka esinjalo sikhuthaza okuvela hypercalcemia, okudinga ukuqapha evamile ye-calcium egazini.

Inani kanye analogue zomuthi

Ingabe uyazi ukuthi kubiza malini "Vigantol"? Intengo yaleli izidakamizwa kungaba ezahlukene futhi ancike inethiwekhi Pharmacy, kanye nendawo yokuhlala isiguli. Ngakho-ke yini ukubaluleka kwaleli thuluzi? Thenga ke unga ruble 200-220.

Kuleso simo ungase ukuthola izidakamizwa ezifana emzini, kungaba kuthathelwe indawo efana. I nozakwabo main ezibhekwa izidakamizwa ezilandelayo izindlela: "Videhol", "Akvadetrim", "Vitamin D", "cholecalciferol", "Kolekaltsiferol" nabanye.

Ukuqhathanisa lezi imithi, abantu abaningi bezibuza ukuthi iyiphi kungcono.

Njengoba yaziwa, ukuze ugweme ukuthuthukiswa yamathambo seziguli ezisencane kusukela ekuzalweni ziqala ukuba linqume imithi ukwandisa Izinga lika-vitamin D egazini. Ngokuvamile, nodokotela bezingane ukuphakamisa ukusetshenziswa kwezidakamizwa ezifana "Vigantol" futhi "Akvadetrim". Ziyakwazi ephumelela kunazo. Nokho, ochwepheshe batusa abazali zihlolwe ne nodokotela bezingane, okusho kubalulekile ukuthatha ingane yabo. Empeleni, kwezinye izimo, isiguli kungcono ukunikeza oily, kuyilapho abanye - isixazululo aqueous.

Ukubuyekezwa umkhiqizo zokwelapha "Vigantol"

Mayelana "Vigantol" ukulungiselela kukhona Izibuyekezo eziningi ezahlukene. Empeleni, basuke kwesokunxele kuya abanezingane ezincane. Phela, izidakamizwa avame ebekiwe izingane nokushoda vitamin D _3.

Ngakho, ngokusebenzisa impendulo abazali ngolwazi yokusebenzisa lolu imithi, futhi bayazibuza ukuthi iye yasiza ezinye izingane.

Ngokusho iningi, nodokotela bezingane ngokuvamile linqume Vigantol izingane ' ". Futhi ngokuvamile sisetshenziswa futhi isixazululo aqueous of "Akvadetrim". Kuzo zombili lezi zimo, izingane waphawula umkhuba omuhle. Ngokuvamile, lokhu kwenzeka ngemuva uwaqede yokwelapha.

Ngokusho kwabazali, ukulungiswa oily kuyinto ikakhulukazi efanelekayo izinsana. Ngemva ukwelashwa abazange phendla phi kwezinso e isakhiwo ithambo.

Kufanele kuphawulwe ukuthi, naphezu kwengozi eliphezulu ukusabela ezingezinhle, amacala nemiphumela engemihle e seziguli ezithola "Vigantola" awufakwanga encwadini. By endleleni, kukhona okuningi okubuyayo ezigulini, okuyinto ejabulisa amanani aphansi lokhu izidakamizwa.