Prothrombin Ukwandiswa kwesikhathi nokuthi yini okufanele uyenze kanjani ukuba ababuyisele evamile. Uyini "isikhathi prothrombin"

Kaningi lapho ukuhlolwa okukhethekile laboratory wembula ukuthi isiguli ikhuphukile prothrombin isikhathi. Yini efakazela ukuthi lungenzeka ushintsho olunjalo? Yeka indlela okuyingozi lesi simo? Kungani kudingeka sinqume isikhathi prothrombin, futhi ubani ikhombisa ukuhlaziywa idatha? Lezi zinkinga esinesithakazelo kuyo abaningi.

Uyini isikhathi prothrombin?

Akuyona imfihlo ukuthi igazi ekunqandeni inqubo kubaluleke kakhulu ukusebenza evamile umzimba womuntu. Ngaphezu kwalokho, igazi iqukethe izici ezithile athiya anda ekunqandeni, kanjalo uvimbele ukudala ezinye ukwakheka amahlule ukuvaleka imithambo yegazi. Ibhalansi emsebenzini zalezi zingxenye ezimbili kuqinisekisa ukusebenza evamile zonke izinhlelo isitho.

Ukuze uqonde ukuthi yisikhathi prothrombin kufanele kubhekwe indlela ezivamile ekunqandeni. Ukulimala odongeni isitsha kubangela ukusebenza enzyme eziyinkimbinkimbi ekhethekile ezihlinzeka kumiswa fibrin imicu. lezi izindikimba kukhona uhlaka enamandla ihlule legazi ithuba lakhe ukuthi. igazi uhlelo ekunqandeni kungenziwa run ngezindlela ezimbili - uma elimele engxenyeni engaphandle noma kwangaphakathi bomkhumbi.

Ngakho, isikhathi prothrombin kusiza ukucacisa okusheshayo indlela uhlelo igazi ekunqandeni kusebenze zangaphandle.

Prothrombin isikhathi, INR futhi prothrombin Inkomba - kuyini?

Ngokwemvelo, ngesilinganiso igazi ekunqandeni uma umonakalo engxenyeni engaphandle odongeni isitsha akuyona inkomba ngokuphelele. By the way, ngokuvamile MF kumele abe phakathi imizuzwana 11 kuya ku-16, futhi ukuze bathole idatha olunembile umsebenzi umzimba, ukuhlolwa eyengeziwe.

Ngo inqubo yokwelapha yesimanje, wasebenzisa International kwesilinganiselo obujwayelekile noma INR. Lapho isifundo esifanayo isiguli prothrombin isikhathi eqhathaniswa Inkomba efanayo plasma kwesejwayelekile namazinga amazwe omhlaba. Ifomula libukeka kanje: PT nesineke / PT plasma kwesejwayelekile (umphumela kuvuselwa ezingeni okuthiwa ngamazwe Inkomba thromboplastin ukuzwela).

Prothrombin Inkomba futhi inquma ratio PV ukulawula plasma PT nesineke plasma, kodwa njengoba amaphesenti. By the way, ngokuvamile index kufanele kube 95 - 100%.

Prothrombin isikhathi Quick namuhla isivivinyo sinembe kakhulu. Lolu cwaningo kusiza ukuqhathanisa umsebenzi lesiguli prothrombin eziyinkimbinkimbi ne ukulawula plasma nemingcele.

Izinkomba ucwaningo

Eqinisweni, kukhona izifo eziningi neziyaluyalu ezithinta inqubo igazi ekunqandeni. Yingakho isifundo esinjalo Kwenziwa njalo ngokwanele. Ngokwesibonelo, iqondiswa iziguli thrombosis okusolwayo. Uhlaziyo futhi libonisa ukuthi uma isiguli wathola imihuzuko eminingi futhi haemorrhages odabuka ongaziwa.

Lolu cwaningo oyisebenzise namanye izinqubo ukuhlola ukusebenza isibindi. Uma usola nokuntuleka noma ukwephula umzimba vitamin K futhi sikuthumele iziguli ahlolwe. Prothrombin isikhathi kunqunywa futhi kwabesifazane abakhulelwe, njengoba le nkathi zezinto eziphilayo zaba khona kusukela ezinye izingozi.

Kanjani ukufeza amasampula kocingo?

Ukuze sithole isikhathi prothrombin, kudingeka plasma fresh. Okokuqala ukuziphatha igazi izibonelo zalokho futhi nesineke. Phela, kulokhu amasampula ethathwe umthambo, uwafake tube equkethe sodium citrate, okuyinto sibopha calcium ion.

Empeleni, abanye ukulungiselela esikhethekile isivivinyo ayidingekile. Ukuzila Ukudla pass igazi, ngakho laboratories kakhulu igazi amasampuli wenziwa ekuseni (ngaphambi amahora 11). Cishe, uzothola imiphumela yokuhlolwa ngosuku olulandelayo. Kufanele kuphawulwe ukuthi izici ezithile kungaba skew imiphumela, ngakho ngaphambi ukuhlola kufanele kudokotela.

Indlela ukunquma isikhathi prothrombin endaweni yokucwaninga?

Definition of isikhathi prothrombin - inqubo lilula. Njengoba sekushiwo, igazi emva izibonelo zalokho ixubene potassium citrate bese uyiswa elabhorethri. Ngokulandelayo, isampuli wanyakaza laying in a Centrifuge ezingeni lokushisa 37 ° ^C. Ngemva kwalokho, isampula ingezwe lemali edingekayo calcium, bese ekunqandeni izicubu isici. Khona-ke aphambana ngesikhathi lapho thrombus kwakhiwa. Njengoba sekushiwo, kufanele kube imizuzwana 11-16.

ukusebenza Ukuthuthukisa

Uma aphakeme prothrombin isikhathi - kuyingozi? Ngeshwa, imiphumela yokuhlolwa musa njalo zivumelana ukubaluleka evamile. Uma kukhona ukwephulwa anda prothrombin isikhathi?

• Kukhona ezinye izifo esingokwemvelo ephelezelwa nokuntuleka izakhi ezijiyisayo.
• Kwezinye izimo lemali obanele of izakhi ezijiyisayo lutholwa. Ikakhulukazi, efana isimo it is ebonwe eziningi izifo sokuhlasela kwamasosha omzimba futhi amyloidosis.
• Ushintsho olunjalo e-IP okwenzeka ngenxa yezifo ye isibindi futhi kubangele isibindi.
• Isizathu kungaba DIC.
• Uma kwenziwa hypovitaminosis K lenyuka prothrombin isikhathi. Ngakwelinye ihlangothi, ukuntula saleli vithamini kungabonakala nasemkhakheni at dysbacteriosis, malabsorption syndrome, kanye nezinye zezifo gallbladder kanye amanyikwe.
• Ukuze uthuthukise yokwamukela MF kuholela ezinye anticoagulants.
• Massive ukumpontshelwa igazi futhi kungathinta imiphumela cwaningo.

Uma izinga lehliselwa

Kwezinye iziguli, prothrombin isikhathi encishisiwe - a thrombus (igazi ihlule) amafomu ngokushesha okuningi kunalokho okudingekayo. Kuba yisikhathi futhi lapho isimo esiyingozi, okuyinto igcwele ukuthuthukiswa occlusion semithambo.

Kaningi, a PV ukwehla kubonisa ukuba khona noma ingozi thrombosis, okuyinto iyingozi kakhulu, njengoba kunjalo ngokuvamile usongo ekuphileni isiguli. Ukwehlisa ngokuvamile uhlanganiswa ukuhambisa amaqembu athile zokuvimbela inzalo hormone. Imbangela kungase futhi kube polycythemia. Kwabesifazane abakhulelwe, amahlule ngokushesha kakhulu yokuthathu yesithathu yokukhulelwa.

Lokhu kungaphazamisa ukunemba ukuhlaziywa?

Ngokushesha kuyafaneleka ukuthi kukhona izinto eziningi, okuyinto ngandlela-thile kungathinta umphumela ukuhlaziya. Njengoba sekushiwo, anticoagulation futhi eminye imishanguzo hormone kungase kwandise ubude thrombus kumiswa. Kodwa kukhona ezinye neminye imikhawulo.

Ikakhulukazi, imiphumela yocwaningo kuzoba wamanga ngomqondo wokuthi icala, uma baphuze ama-aspirin, barbiturates, nemithi equkethe Vitamin K. Ngaphezu kwalokho, isikhathi prothrombin, futhi kuthinta amaqembu athile kwama-antibiotic.

ukuqunjelwa kungathikameza imiphumela ukuhlaziywa. Ikakhulukazi, uhudo ophikelelayo, noma njalo ukuhlanza phambili ekuphelelweni amanzi emzimbeni. Ngaphezu kwalokho, izinqubo ziphuliwe ukumuncwa amavithamini namaminerali, kuhlanganise tocopherol (vitamin K) e zinkinga.

Uma udle ukudla aqukethe esiningi vitamin K, imiphumela yokuhlolwa kungase kube okungaqondile. Ezinsukwini ezimbalwa ngaphambi Assay silinganisela yengulube kanye yenkomo kwesibindi, imikhiqizo soy, uphizi, itiye eliluhlaza, iklabishi, broccoli kanye oluhlaza.

Inqubo igazi coagulation umphumela notshwala, ngakho, futhi, ezinsukwini ezimbalwa ngaphambi test uphuzo oludakayo kufanele uyekwe.

Izimo letitsintsa umjikelezo komsebenzi ingase ihlanganise laxatives ethola futhi eminye imishanguzo homeopathic.

Uma imithi oyiphuzayo, qiniseka ukuthi utshele udokotela wakho. Tshela Uchwepheshe mayelana izici ekudleni kwakho kanye nezinkinga zempilo samanje. Kungenjalo, ukuhlaziywa akuyona ulwazi, futhi udokotela angase linqume izidakamizwa lungafanelekile ngokuphelele.

Kungani ukunquma isikhathi prothrombin, owesifazane okhulelwe?

Kuyinto imfihlo ukuthi ngesikhathi umzimba owesifazane yokuzala sika (ikakhulukazi kwegazi futhi endocrine uhlelo) kungokoqobo izinguquko ezinkulu. Yingakho ukunquma isikhathi prothrombin ngesikhathi sokukhulelwa kubaluleke kakhulu.

Abanye besifazane kule nkathi lenyuke igazi ekunqandeni, okuholela thrombosis futhi occlusion yegazi ukuthi athwala igazi emzimbeni wengane. Lapho iyekwa ingelashwa ukuhlukumeza okunjalo kungaholela eqonda coagulation intravascular, ngisho nokufa umbungu.

Ngakolunye uhlangothi, igazi kungase kube thinning kakhulu ngesikhathi sokukhulelwa. Ezimweni ezinjalo, kukhona ingozi enkulu ye omkhulu ukopha, ikakhulukazi ngesikhathi sokubeletha. Definition of isikhathi prothrombin kwenza udokotela ukuba ngesikhathi esifanele ukuthola ukuhlukumeza ethile futhi kuvimbele ukuxakeka.