"I-Glyformin" elesifo sikashukela: amanani, izibuyekezo kanye nezifaniso

Isidakamizwa esithi "i-Glyformin" singeqembu le-biguanide. Kuyinto imithi ye-hypoglycemic eyanciphisa ukumuncwa kwe-glucose futhi kwandisa kanye nokuzwela kwezicubu ezithile kwi-insulin. Kusukela ezintweni ezikulesi sihloko, uzothola ukuthi yiliphi isilinganiso esinqunyiwe esithi "Gliiformin" uma isifo sikashukela, izindleko zemithi kanye nezimpendulo zeziguli zangempela.

Ukwakhiwa kanye nefomu lokukhululwa

Isidakamizwa siqhubeka sithengiswa ngendlela yamathebulethi, okungaba ngamabili amabili:

• Amaphilisi e-Ploskotsilindricheskie enombono ohlukanisayo wombala omhlophe (0,5 g wezinto ezisebenzayo). Iphakanyiswe ngezicucu eziyi-10 ngepakethe yeseli.
• Amaphilisi esembatho sefilimu somthunzi omuncu (0.85 noma 1 g wezinto ezisebenzayo). Iphakanyiswe ngezimbiza ze-polypropylene wezingcezu ezingu-60.

Isithako esisebenzayo yi-metformin hydrochloride.

Isenzo sempilo

"I-Gliiformin" yesifo sikashukela kufanele ithathwe kuphela ngomlomo. Indlela yokusebenza kwezidakamizwa ezisekelweni zezitho zangaphakathi azizange zifundwe kuze kube sekupheleni.

Ukungena emzimbeni, into esebenzayo ibandakanyeka kulezi zinqubo ezilandelayo:

• Ukususwa kokubunjwa kwama-molecule we-glucose esibindi.
• Ukusebenza kwe-carbohydrate cleavage.
• Ukwehlisa ivolumu yeglucose ephuma emathunjini.

Ukusetshenziswa kwesidakamizwa "Glyformin" esifo sikashukela nokukhuluphala kuholela ekunciphiseni kwesifiso, isisindo somzimba. Imiyalelo ithi imithi ikhuthaza ukuchithwa kancane kancane kwezindwangu zegazi futhi ivimbela amapulelethi ukuba angafaki.

I-Metformin hydrochloride isheshe ifakwe ama-cell of the digestive tract. Ukuhlushwa okukhawulelwe kwezinto ezisebenzayo kulungiswa emva kwamahora amabili kusukela ngesikhathi sokuphatha. I-bioavailability yayo cishe cishe ngama-50-60%. Isidakamizwa asihlangene namaprotheni e-plasma, kancane kancane iqoqa ohlelweni lwezitho zangaphakathi. Ukusuka emzimbeni into ekhishwa cishe ingashintshi.

Izimpawu zokusetshenziswa kwezidakamizwa "Gliiformin"

Imiyalo yamathebulethi yokusetshenziswa uncoma ukuthatha iziguli ngezibalo ezilandelayo:

• Uhlobo lwesifo sikashukela, uhlobo lwesifo sikashukela II, lapho i-dietotherapy ne-sulfonylureas engasebenzi.
• Thayipha I-diabetes mellitus (ukwengeza ku-standard insulin therapy).

Ngesikhathi sokwelashwa, ukuhlolwa okuqhubekayo kwezinso zezinso kuyadingeka, kanye nezinyanga eziyisithupha kunconywa ukuba uhlole amanani we-lactate e-plasma yegazi.

Indlela yokusebenza

I-Gliformin enqunywe yisifo sikashukela esilinganisweni esingakanani? Ngokweziqondiso, amaphilisi kufanele athathwe ngesikhathi / emva kokudla, futhi kufanele athathwe ngamanzi. Isilinganiso esikhethekile kanye nobude besikhathi sokwelashwa umiswa udokotela, ngokucabangela amagugu weglucose egazini likagulane.

Esikhathini sokuqala sokwelashwa (izinsuku eziyi-15 zokuqala), umthamo awukho ngaphezu kwegremu elingu-1 ngosuku. Bese kwanda kancane kancane. Umthamo wesondlo ngokuvamile awudluli u-2 g ngosuku. It ngokulinganayo ihlukaniswe zibe reception eziningana.

Kuziguli zokuguga, umthamo wansuku zonke wezidakamizwa awukho ngaphezu kwe-1 g.

Izenzakalo ezimbi

Uma udokotela eqoka "i-Gliiformin" yesifo sikashukela, ukubuyekezwa kweziguli zangempela kungaba ukuhlola ukusebenza komuthi. Njengeminye imithi, ingabangela imiphumela eminingi emibi:

• Uhlelo lwe-endocrine: i-hypoglycemia.
• Ukujikeleza: i-anemia.
• Ukusabela okweqile: ukuvuthwa, izikhala.
• I-metabolism: hypovitaminosis.
• Uhlelo lwesisu: ukungabi nesifiso, isicanucanu, ukunambitheka kwensimbi emlonyeni, ukuhlanza, isifo sohudo.

Uma kunemiphumela emibi, kufanele uyeke ukuthatha amaphilisi okwesikhashana uphinde uthintane nodokotela.

Ukungafani

Iziqondiso kumuthi zithi ukuphathwa kwawo akukhuthazwa kulezi zimo ezilandelayo:

• I-coma yesifo sikashukela ;
• I-Ketoacidosis;
• Ukuhluleka kwepulmonary / inhliziyo;
• Izifo zesibindi ezingapheli;
• I-infarction ye-myocardial;
• Ukuzwela okwedlulele ezingxenyeni ezifakwe ekufakweni;
• Ukukhulelwa nokulahlwa.

Ngokunakekelwa okhethekile, kufanele usebenzise i- "Glyformin" kusuka kusifo sikashukela esivela ku-pathologies yesimo esithathelwanayo, ngaphambi kokusebenza okungathí sina.

Ukusebenzisana kwezidakamizwa

Ngokweziqondiso, ngokusetshenziswa kanyekanye nge-insulin, izidakamizwa ezingezona izifo ezivuvukala, izidakamizwa ze-sulfonylurea, i-beta-adrenoblockers, isenzo se- "Glyformin" asikhiphi.

Ukusebenza kwalo kunganciphisa kakhulu ngokulandelana kokwelashwa okwengeziwe nge-glucocorticosteroids, ukuvimbela izitho zomlomo, amahomoni wegciwane, ama-nicotinic derivatives, ama-diuretics.

Izimo nezindleko zokugcina

Isidakamizwa kufanele sigcinwe emazingeni okushisa ama-degree angama-25 endaweni evikelwe izingane. Ukuphila kwe-Shelf iminyaka engu-3, futhi amaphilisi emgodleni wefilimu - iminyaka emibili.

Kungakanani "i-Gliiformin"? Ngesifo sikashukela, inani lemithi lidlala indima ebalulekile iziguli eziningi. Umuthi ochazwe kulesi sihloko awubizi kakhulu. Ukuze upake amaphilisi egobolini lefilimu, kuzomele unikeze ama-ruble angaphezu kuka-300. Amaphilisi anomzimba ohlukanisayo (0.5 g wezinto ezisebenzayo) ayhibhile - ama-ruble angu-150.

Ama-analogues

Uma bethenga i-Gliiformin, ukusetshenziswa, imfundo, impendulo yinto yokuqala iziguli ezitholayo. Ngenxa yobuningi bokungafani, imithi eminingi ayifanelekile. Ungakhetha izidakamizwa ezifana nezakhiwo zemithi emva kokubonisana nodokotela.

Phakathi kwama-analogues amaningi ahambisana ne "Glyformin" kokuqukethwe komuthi osebenzayo, okulandelayo kuvelele: "Isifo sikashukela", "Metformin", "Glucoran".

Ukubuyekezwa kweziguli nodokotela

Iziguli eziningi ezazinqunywe le mithi yokwelashwa, zaphawula ukuthi kungenzeka ukuthi kuningi ngokweqile. Ezimweni eziningi, kubangelwa ukusetshenziswa okungalungile kwemithi. Ukudlula ngokweqile kungabangela ukuthi kwenzeke okuthiwa i-lactic acidosis. Izimpawu zayo eziyinhloko yilezi: ubuhlungu emisipha, ukuhlanza kanye nokucabangela, ukungazi kahle. Uma isiguli sinesibonakaliso esinjalo, kunconywa ukuthi siyeke ukuthatha imithi bese ucela usizo kudokotela.

Ezingxenyeni zengcweti, ukubuyekezwa kuningi ezimweni ezinhle. Yingakho i-Gli-formin ivamise ukuba ibekwe isifo sikashukela. Inani lemithi liphansi, lingathengwa cishe kuwo wonke ama-pharmacy. Uma ulandela imiyalelo ngokucacile, amathuba okuba nemiphumela emibi iphansi. Odokotela baxwayisa ukuthi kulo lonke ukwelashwa izikhathi ezingu-2-3 ngonyaka kumele bahlolwe i-serum creatinine. Ngesikhathi sokwelashwa, utshwala nemithi kufanele ihanjiswe nge-ethanol.

Ake sibambe imiphumela

Isifo sikashukela sinesifo esivamile, esicubungula kakhulu namuhla kubantu abasha. Ngokwelashwa kwakhe, odokotela banquma imithi ehlukahlukene. "I-Gliiformin" iphinde ibhekisele kwinombolo yabo. Lena imithi ye-hypoglycemic ehlose ukwandisa ukuzwela kwezicubu ku-insulin. Uma uyithatha ngokuhambisana nemiyalelo kanye nesidakamizwa sikadokotela, akufanele kube nemiphumela emibi. Kubalulekile futhi ukucabangela ukuphikisana komkhiqizo wokwelapha.