Carcinoma ne-squamous wesibeletho: Izibikezelo, ukwelashwa

Ngokwezibalo, neoplasia wesibeletho (CIN), okusho ukuthi umdlavuza, ungumholi e isakhiwo umdlavuza. Ngokuvamile, umuntu angakwazi izicubu evamile e-isimila siyenzeka ku wesibeletho. Lokhu kungenxa epithelium. Ngenxa carcinoma ne-squamous wesibeletho libhekisela amafomu ezivamile izifo umdlavuza, ukuqhuba uphethwe zalo zokuqala. Njengoba sekunama-izinhlelo ezikhethekile Ukuhlolwa zingatholakala hhayi kuphela izigaba kokuqala kwe-isimila, kodwa futhi isimo atypia ngaphambi. ekuhlonzweni nasekwelashweni yomdlavuza wesibeletho enze kube nokwenzeka ukuba ugcine eziningi abesifazane. Ngakho-ke zokugula isibikezelo namuhla ngaphansi eyinhlekelele.

carcinoma ne-squamous wesibeletho - kuyini?

Umdlavuza womlomo wesibeletho ubhekwa esematheni hhayi kuphela lodokotela, kodwa futhi yonke wesifazane. Kusukela waqala zokuvimbela asebenzayo lesi sifo futhi uphethwe yayo, bezwa isikali omkhulu lesi sifo. Umdlavuza obujwayelekile wesibeletho squamous. Lolu hlobo lwesimila Kuyaziwa ukuthi izakhi atypical avela epithelium beya multilayered ukuthi olayini ectocervix. Ngamanye amazwi, lolu hlobo lomdlavuza itholakala endaweni lapho wesibeletho ingena esithweni sangasese.

Ezweni lanamuhla lokhu isifo ihlobene omunye pathologies ezivamile oncological. Ektotserviksa kwesifo somdlavuza kuyinto 15 abayi-100,000 labantu. Naphezu kwaqobe mnyaka ngokwempilo yangenyama kusukela lesi sifo, isifo Izibikezelo ivame ukuba ngcono. Uma ngaphambili abanomdlavuza womlomo wesibeletho squamous kutholakala ukuthi uphethwe yini kuphela izigaba lokugcina impatho manje isiqala kwenye eselitholile izici kusukela ungalokothi uphuze.

Njengazo zonke isifo umdlavuza izifo zabesifazane, neoplasia wesibeletho isikhathi eside ayinakho ukubonakaliswa emtholampilo. Ngakho-ke kubalulekile ukuba banake izinguquko kancane ezenzeka emzimbeni, kanye ukuvakashelwa gqwa kuya wezifo zabesifazane.

Izimbangela yomdlavuza wesibeletho

Ukubukeka neoplasia squamous elihlobene ne izici ezahlukene etiological. Ikakhulukazi le osebenza ku ukwephulwa ohlelweni endocrine. Kukholakala ukuthi kukhona okusobala phakathi izifo zabesifazane umdlavuza zokugula kanye nesimo kwama-hormone ngesikhathi umzimba female. Ngokuvamile ukuthola umdlavuza wesibeletho kuyinto kwamazinga estrogen. La ma-hormone akhiqizwa ezikhiqiza amaqanda. Ngezelela noma nciphisa izinga labo ilawulwa hypothalamus. Banikezwe ubuhlobo lesi sifo nge endocrine neziyaluyalu, kulokhu okulandelayo izimbangela eyaziwayo wesibeletho umdlavuza poppy:

1. ukusetshenziswa kwesikhathi eside nokukhandela imbeleko. iningi lezindlela zokuvimbela inzalo yakhiwa estrogens. Ngakho-ke, ukusetshenziswa COCs kuyadingeka ngezikhathi ezithile ukubona udokotela ukunquma izinga lama-hormone.
2. Ukwelashwa nge "Tamoxifen" futhi analogue yayo. I nomuthi elisetshenziswa wokwelapha isifo somdlavuza webele. Noma kunjalo, izidakamizwa kumele kusetshenziswe ngokuqapha okukhulu, ngoba kubuye hormone.
3. yegilo (i-hypothyroidism), ukukhuluphala nezifo. Lezi iinkhathi nanesandla amazinga estrogen futhi emdlavuzeni wesibeletho.

Ngaphezu kwalokho, kunezinye izici ezinomthelela. Phakathi kwabo: izifo ezingamahlalakhona zangasese, isisu, inani elikhulu ukukhulelwa nokuzalwa, kanti ukungezwakali yabo ephelele. Wesibeletho-squamous cell carcinoma ngokuvamile kwenzeka ngokumelene isizinda pathologies ezifana polyp, ukuguguleka komhlabathi, leukopenia futhi erythroplakia dysplasia. Eminyakeni yamuva, lesi sifo elihlobene ne-HPV izinhlobo 16 no-18 Abacwaningi esefinyelela kulesi siphetho, ngoba lokhu lwegciwane litholakala cishe kuyo yonke iziguli neoplasia wesibeletho.

Izinhlobonhlobo-squamous cell carcinoma

Sikhishwe ubunjalo amaseli EPITHELIAL ukuthi ibhekane atypia, ukukhomba izinhlobo eziningana neoplasia wesibeletho:

1. Adenocarcinoma. Lolu hlobo kuba abanye bungavami.
2. Keratinizing carcinoma ne-squamous wesibeletho. Libhekene kumiswa yi-keratin elimbudumbudu surface EPITHELIAL. sici Yokucwaninga yalesi sifo ezibhekwa "amapharele umdlavuza." Smear kuhluka ukubukeka, usayizi amaseli jagged.
3. Low-grade lwesimila. Kuyinto engenakwenzeka ukunquma ukuthi yiziphi izakhi yeselula eziye zabhekana atypia. Lokhu samuntu Ngakho okungekuhle.
4. Neorogovevayuschy squamous umdlavuza wesibeletho. Kuhambisana nokuntuleka yi-keratin. I smear ebonakalayo emizimbeni okusaqanda enkulu equkethe cytoplasm eosinophilic.

I degree of neoplasia wesibeletho

Phezu ukuthola neoplasia (CIN) kuyadingeka ukuze ukuqhuba ucwaningo ukuthola umsuka wendaba yesihluku ukusakazeka kwalo. Uma ucabangela ukuthuthukiswa lamaseli atypical, 4 isifo esiteji. Lesi sigaba ku degrees ikuvumela ukuthi ukhethe ukwelashwa okufanele futhi ukunquma Izibikezelo. Isiteji 0 libhekisela umdlavuza non-koda, okungukuthi, amaseli normal ayatholakala ku kobuso epithelium, kodwa akazange ukungena emaqaqasini izicubu wesibeletho. degree Okokuqala - isimila prorosla ukujula mm eziningana. Ngu lokhu kwakusho ukuthi ithuthukiswe koda cell-squamous umdlavuza wesibeletho, uya ngalé kwemingcele emzimbeni. Esikhathini yesibili esiteji neoplasia kudlulela ipharamitha noma engxenyeni engenhla sangasese. Izinga lesithathu libhekene ukubonakala amangqamuzana omdlavuza ezindongeni ukhalo. Futhi ukunqoba obala engxenyeni engezansi sangasese, yesifunda zamanzi. Ngo isinyathelo 4 ukuqhutshwa kuya kwesinye isimila noma emathunjini. Kukhona metastases ezikude.

Lwasemtholampilo isithombe umdlavuza wesibeletho

Okusolwayo CIN kunzima, njengoba cishe akukho izici isici. Ekuqaleni, le umdlavuza akubonakali noma inezimpawu njengokuya esikhathini okungajwayelekile, ubuhlungu esiswini kanye ephansi emuva, ecacile ngoketshezi oluphuma esithweni sangasese. Isici nobuntu contact kubhekwe ukuba ukopha ukuthi kwenzeka ngesikhathi ocansini. Kamuva uphawu kubhekwe aphansi emkhawulweni edema, ongaphakeme-ebangeni imfiva. Ngesikhathi esigabeni yokugcina isisindo ngokuphawulekayo ukulahlekelwa, ubuthakathaka, ukungakuthandi ukudla lymph evuvukele ISIZINDA e imbilapho.

Ukuxilongwa cell-squamous umdlavuza wesibeletho

Ukukhomba-squamous cell carcinoma Kwenziwa njengoba kwaba njalo endabeni ka izikhalazo, kanye ukuhlolwa. Kuyinto ukuhlaziywa ekhethekile, esithathelwe swab sangasese kanye wesibeletho (PAP-test). Nale ndlela kungenzeka ukunquma hhayi kuphela umdlavuza, kodwa futhi dysplasia - izinguquko ezincane ukwakheka kwamangqamuzana. Lapho colposcopy Equivocal wenziwa usebenzisa acetic acid iodine (ukuhlonza izindawo sisola epithelium). Uma umdlavuza okusolwa, a biopsy wesibeletho kuyadingeka. Esinye cwaningo ukuzimisela HPV.

Wesibeletho Umdlavuza Ukwelashwa

squamous ukwelashwa komdlavuza wesibeletho kuhlanganisa nokususwa kuhlinzwa yesimila, amakhemikhali okwelapha nemisebe yokwelapha. Umthamo ukuhlinzwa kuncike esigabeni, kanye engu-isiguli. Lapho neoplasia non-koda, noma 1 degree ukuchitha hysterectomy, kokushiya amaqanda. Lo msebenzi kuboniswa iziguli uyakwazi nje ebamba isisu. Uma isiguli ukuya esikhathini, khona-ke wenza hysterectomy, ukususwa ezihlobene futhi omentum okukhulu. operation ivolumu ezinjalo kudingeka ngenxa yokuthi kukhona ingozi Ukudlulela noma isimila Ukuphinda. Futhi bona yokwelapha nabenzeli hormone. In the isinyathelo sokugcina Kwenziwa kuphela ukwelashwa lingaze.

Squamous umdlavuza wesibeletho: Izibikezelo

Naphezu okusezingeni eliphezulu lokufa, umuntu angalulama. Lokhu kusebenza iziguli neoplasia, kwatholakala ukuthi nginesifo kusaqalwa. engu-rate sokusinda emva kokwelashwa ezomhlaba mayelana 55%. izinguquko Inkomba ngenxa isimila esiteji (-1 degree 78%, 4 - 7.8%).

Izinyathelo ukuze bagweme umdlavuza

The main isilinganiso zokuvimbela ukuvakashela udokotela wezifo zabesifazane okungenani isikhathi esingu-1 ngonyaka. Kubalulekile futhi ngesikhathi ukuze yelaphe izifo ezibangelwa zangasese, hhayi ukusebenzisa elihlangene zokuvimbela inzalo temlomo iminyaka engaphezu kuka-5, ngezikhathi ukunquma izinga lama-hormone. Ephambi kwezinduna izici ungalokothi uphuze (ukuguguleka wesibeletho, polyp, leukoplakia) kudingeka alandele colposcopy. Esikhathini esizayo, udokotela lizobe esethatha isinqumo mayelana nokwelashwa kwezifo ngemuva. Eminyakeni yamuva, bakhula zokuvimbela ezithile umdlavuza wesibeletho - lokugoma okuhloswe ngaso HPV izinhlobo 16 no-18 Kunenkolelo entsheni. Ngaphambi yokugoma, kufanele uxhumane nodokotela wakho.