Ukwelashwa ngama-antibiotic kungandisa kakhulu ingozi yokukhulelwa kwesisu

Abesifazane abathetha izinhlobo ezithile zama-antibiotic ezinyathelweni zakuqala zokukhulelwa kungenzeka ukuthi bangengozi yokukhulelwa kwesisu, ososayensi bakhombisa.

Idatha entsha evela ososayensi baseCanada

Kodwa akuwona wonke ama-antibiotic asebenza ngendlela efanayo, kanti amanye angaphephile ngesikhathi sokukhulelwa kunabanye. Abacwaningi baseCanada bathola ukuthi abesifazane abakhulelwe abadle izinhlobo ezithile zama-antibiotic babe nokwanda okuncane engozini yokukhulelwa kwesisu phakathi kwamasonto amabili okuqala okukhulelwa uma kuqhathaniswa nomama ozayo abangazange bathathe. Imiphumela yalolu cwaningo yanyatheliswa ngoMeyi 1 encwadini ye-Canadian Medical Association.

"Ucwaningo lubonise ukuthi ama-antibiotic - ipenicillin, i-cephalosporin ne-erythromycin - ayinaso umthelela engozini yokukhulelwa kwesisu," kusho umlobi ohola u-Anik Berard, uprofesa wekhemisi eYunivesithi yaseMontreal eCanada.

Izifo ezithinta abesifazane ngesikhathi sokukhulelwa zidinga ukwelashwa, ngakho-ke kuyakhuthaza ukuthi ufunde ukuthi ama-antibiotics asetshenziselwa kakhulu akuyona imbangela yokukhulelwa kwesisu ekuqaleni kwezigaba zokukhulelwa.

Izinkinga Zokuphepha

Naphezu kokusetshenziswa kwama-antibiotic njalo ngesikhathi sokukhulelwa ukwelashwa kwezifo ezehlukene, ukuphepha kwemiphumela yalezi zidakamizwa ebusweni kuyisimo esiyinkinga, abalobi bokutadisha bathi. Lokhu kungenxa yokuthi izifundo zangaphambilini zobudlelwane phakathi kokusetshenziswa kwama-antibiotic ngesikhathi sokukhulelwa kanye nengozi yokukhulelwa kwesisu zazingxabano. Abanye ososayensi bathole ukuhlobana phakathi kokusetshenziswa kwamakilasi athile ama-antibiotic ngesikhathi sokukhulelwa nokukhulelwa kwesisu, kanti abanye abazange baqinisekise lokhu.

Izinzuzo zokusebenzisa i-database

Esicwaningweni esisha, abacwaningi bahlola idatha ngesikhathi sokukhulelwa kwabesifazane baseQuebec phakathi kuka-1998 no-2009. Le database iqukethe ulwazi mayelana nabesifazane abakhulelwe esifundazweni, okwakusungulwe uhlelo lukaHulumeni waseQuebec lwe-inshuwalense yezidakamizwa. I-database ihlanganisa idatha eningi labesifazane abakhulelwe esifundazweni.

Ngakho-ke, abacwaningi babeqiniseka ukuthi basebenzise ulwazi olunembile mayelana nemigomo yemithi elwa namagciwane okubekelwe omama esikhathini esizayo, okwakwenza ukuba bangaxhomeki emandleni abo besifazane ukukhumbula ukuthi imiphi imithi ayisebenzisayo, ngoba lokhu kuyinkomba encane engathembeki.

Yiziphi antibiotics eziyingozi kubesifazane abakhulelwe

Abacwaningi baqhathanisa amacala abesifazane abangaphezu kuka-8 700 abaye bahlaselwa isisu phakathi kwamasonto amabili okuqala, kusukela kwabesifazane abangu-87 000, abakhulelwe abazange babe nezinkinga. Ubudala besifazane ocwaningweni buphakathi kweminyaka engu-15 kuya kwezingu-45. Kwakukhona ukuthi cishe abangaba ngu-12 500 bathatha ama-antibiotics ngesikhathi sokukhulelwa.

Ucwaningo lubonisa ukuthi amakilasi amahlanu e-antibiotics - ama-macrolide, ama-quinolones, i-tetracyclines, i-sulfonamide ne-metronidazole-angandisa ingozi yokukhulelwa kwesisu uma owesifazane esesiteji sokuqala sokukhulelwa. Ososayensi baphawula ukuthi enye i-macrolide antibiotic, i-erythromycin, ayihlanganisiwe nale ngozi.

Lezi idatha zihambisana nemiphumela etholakala kwezinye izifundo zangaphambilini, kodwa ubuhlobo phakathi kokudla kwe-fluoroquinolones kanye ne-tetracyclines kanye nengozi yokukhulelwa kwesisu akuzange kutholakale ngaphambili. Kodwa-ke, okwamanje, izidakamizwa azitusa ukusetshenziswa kwe-fluoroquinolones kanye ne-tetracyclines ezinkathini zokuqala zokukhulelwa, futhi lemiphumela ibonisa ukuthi iseluleko esinjalo sinengqondo.

Ingozi ephansi

"Nakuba lolu cwaningo lubonisa ingozi eyengeziwe yokwehlukaniswa kwamaphutha kwabesifazane abazithatha izinhlobo ezithile zama-antibiotic, ngokwalo kuphansi," kusho uProfesa Berard. Ukusebenzisa ezinye izidakamizwa eziningi, njengezidakamizwa ezingezona izidakamizwa eziphikisayo nezidambisigciwane, nazo zahlanganiswa nengozi efana nokwanda kwamaphutha.

Ukunciphisa ingozi yokukhulelwa kwesisu

Enye izindaba ezinhle ukuthi i-antibiotic evamile, i-nitrofurantoin, evame ukubekwa uma owesifazane enezifo ezithinta umchamo, empeleni ahlanganiswe nengozi encane yokukhulelwa kwesisu ngokuqhathaniswa neqembu lokulawula. Lolu cwaningo luyilokuqala olubonisa lolu xhumano, ngakho-ke ososayensi abazayo kumele baqinisekise lesi siphetho esisha.