"Pomalidomid" (imnovid): the nozakwabo intengo. Njengoba ukuthenga a "Imnovid"?

Pomalidomid - buyisidakamizwa okungokukaNkulunkulu isizukulwane esisha anti-isimila modulators mzimba. Lokhu kwaziswa possesses zabonakala zikwazi ukunqanda stromal (stem) amaseli ukusekela ukuthuthukiswa kanye nokukhula myeloma. Ngaphezu kwalokho, kubangela apoptosis (yokufa amaseli engaphelele) futhi ayanda kuvimbela (izicubu ukukhula).

Ucwaningo kwenziwa kuye kwabonisa ukuthi ngokusebenzisa pomalidomida 52% sehliselwe phambili yokuphila kanye neminyaka okulindeleke kakhulu lenyuka.

Uchaza into sivunyiwe e-US for ekwelapheni refractory myeloma amaningi futhi wehluleka. Kukhona iyatholakala ngaphansi kwegama ukuhweba "Pomalist" e-EU njengoba yaziwa ngokuthi "Imnovid".

Ngingalutholaphi ukuthenga izidakamizwa ashibhile equkethe pomalidomid

Ngaphambi kokuthi uqhubeke incazelo isenzo pomalidomida, kufanele kuphawulwe ukuthi izidakamizwa kwadingeka kwezinhlelo wokwelapha isifo somdlavuza, ezibizayo. Futhi le nkinga ngoba iziguli ukuthi ukwelashwa uphazamisa ayikho indlela kodwa akhokhe yonke inkambo yokuhle - kuyinkinga kakhulu. Ngakho, eMoscow emuthini uphawu eziqukethe intengo pomalidomid igcina emhlabeni 819.000 ruble.

Kulesi simo, lapho uyofika kosizo www.onko24.com indawo owaziwa. Lapha ungakwazi ukuthenga imithi ejwayelekile eliqukethe isithako efanayo esebenzayo - pomalidomid, intengo kubo ngesikhathi esifanayo ezokhokheleka okuningi. Futhi lokhu akuyona ngenxa ikhwalithi embi lokulungisela kanye neqiniso lokuthi inkampani abadumile Indian okuveza ke, kwaba akudingekile ukutshala ocwaningweni, ukuthuthukiswa kanye nokukhangisa. Yena kuphela babethenga amalungelo isidakamizwa, echaza izindleko zalo iphansana, ne ukusebenza kahle efanayo.

Sokuphuzisa nokulungiselela sokuphuzisa

Pomalidomid kukhonjisiwe nokwelashwa kweziguli iminyaka engu-18 noma ngaphezulu, abanale kubonakale inchubekelembili refractory myeloma amaningi ezilandelayo okungenani 2 izifundo ukwelashwa nge bortezomib futhi lenalidomide.

Sebenzisa ithuluzi ngaphakathi, kanye dexamethasone, 4 mg kanye insuku zonke, okwensuku 21, ngemva kwalokho kudingeka ikhefu ngeviki.

Umuthi kumele kwenziwe amahora efanayo nsuku zonke, kungakhathaliseki ukuthi izikhathi ukudla. Ukuhlafuna noma eyothando amaphilisi engenakwenzeka. Uma isinyathelo esisodwa is ezingabanjwanga ke ngosuku olulandelayo akudingeki baphuze umthamo double.

Nge ukuqhubeka ekwelapheni isifo imiswe okwesikhashana.

Izimo

Musa linqume izidakamizwa equkethe pomalidomid, izingane ezingaphansi kweminyaka engu-18 ubudala kanye nabesifazane abakhulelwe. Ibele ngesikhatsi ukwelashwa ngokuthi ejenti kumele kunqanyulwe.

Isimo kweziguli ukungakhuli so-renal kanye hepatic kufanele baqashwe ngudokotela wakho ngoba kusenesikhathi ukusabela ezingezinhle.

isicinganani

(. "Imnovid", "Pomalist", njll) Lapho ekwelapheni amalungiselelo equkethe pomalidomid, ukubonakaliswa miphumela elandelayo enqabayo kungenzeka ezigulini:

• ukukhathala;
• okuvela kuyo ikhanda, isiyezi, futhi ukudideka;
• ukucanuzela kwenhliziyo, ukuhlanza,
• ukungakuthandi ukudla;
• izinkinga zesisu ukusebenza;
• kwegazi, thrombocytopenia;
• okuvela imisipha amajaqamba futhi kuyoba khona ubuhlungu emathanjeni;
• ukuthuthukiswa kwezifo ezithathelwanayo elingenhla ipheshana zokuphefumula;
• ukuqubuka.