Izidakamizwa "Colchicine". Yokusetshenziswa

Izidakamizwa "Colchicine" kuyinto iqembu alkaloids namanye amanxusa isitshalo-etholakala cytotoxic. Umuthi has protivopodagricakih, umphumela analgesic. ejenti Antimitotic kuyalithinta ezivimbela lymph kanye leykopoez kunciphisa kulahlwa glucose nefagotsitiruyuschimi futhi leukocyte phagocytic, evimbela kumiswa amyloid fibrils. Imithi kunomthelela ukuhlukumeza ukudluliswa kwamanyuroni, sikhuthaze emathunjini ipheshana umsebenzi. Kusho ukusebenza ezicindezelayo ezikuyi-kwemigudu yokuphefumula isikhungo kanye inyuka ingcindezi, constricts imithambo yegazi, kunciphisa izinga lokushisa. Eyanele wokugaya ukudla ngokushesha. Umuthi sihamba recirculation enterohepatic. lokuhlala High kwezidakamizwa zitholakala ubende, isibindi kanye nezinso. Ukuhoxiswa izimali ngokusebenzisa nezinso Bile.

"Colchicine" imithi. Yokusetshenziswa. ubufakazi

Kusho okunqunywe sokuhlasela gouty, nokuvimbela yokuphindela ukuhlaselwa acute gouty uhlamvu, ikakhulukazi phakathi neminyaka emibili yokuqala ngemva kokuthola imithi gipourikemicheskih. Ngu izinkomba zihlanganisa scleroderma letindzala, isifo Behcet sika, amyloidosis, ngofuzo imfiva iMedithera.

"Colchicine" imithi. Yokusetshenziswa. isicinganani

Ngesisekelo yokwamukela nomuthi lungase lubonwe izimpawu dyspeptic. Ikakhulukazi, isicanucanu, uhudo, ukuhlanza, nokuzincisha ukudla. Ngokuvamile, lezi zimpawu ayisibonelo isimo ngemuva kokuthatha ebulilini. Imiphumela emibi zihlanganisa Alopecia yesikhashana, amazinga aphakeme gamma-glutamyl futhi ane-alikhali phosphatase, ukwehluleka hepatic, iziyaluyalu nezinso. Umuthi kungabangela myelosuppression (leucopenia, anaemia aplastic, agranulocytosis, thrombocytopenia), myopathy, ukucindezeleka spermatoschesis emuva. Phakathi ukwelashwa imakwe neuritis neuropathy, iguliswa isikhumba ukusabela, malabsorption syndrome ubonakalisiwe, ngokukhethekile, ukuntuleka vitamin B12. Lapho iqondiswa ngemithambo yegazi, kukhona ukucasuka wendawo.

"Colchicine" lisho ukuthini. Yokusetshenziswa. Ukuze uthole ukwaziswa okwengeziwe,

Umuthi uyakwazi ukuthuthukisa isenzo izidakamizwa sympathomimetic futhi deprimiruyuschie. Ngesisekelo isicelo kukhona absorbability ukwephulwa vitamin B 12. Lapho kuhlangene yokwamukelwa nezinye izidakamizwa NSAID, ingqondo mielodepressiu kwandisa amathuba thrombocytopenia futhi leukopenia. izidakamizwa cytotoxic uyakwazi ukwehlisa umphumela protivopodagricakih (nesanda uric acid).

Izidakamizwa "Colchicine". Yokusetshenziswa. ukweqisa izidakamizwa

Uma ushevu ephawulwe imithi ukucanuzela kwenhliziyo, ubuhlungu emlonyeni esiswini, uhudo olubi ukuhlanza, oluhambisana Gastroenteritis. Ukuze isimo ukweqisa izidakamizwa libhekene umuzwa lwalapho kushiswa khona isikhumba, kwehle contractility esivimba amanzi, amanzi emzimbeni nge ukushaqeka hypovolemic futhi hypotension, hematuria, Ukudlikizela, ukucindezeleka zokuphefumula, sinyuka ukukhubazeka, oliguria. Mhlawumbe okuvela kuyo umonakalo hepatocellular, acute kwezinso ukwehluleka ukugeleza, lingene yamaphaphu. Ngemva kwezinsuku eziyisihlanu bebe izidakamizwa ubuthi kungaqala umnkantsha ukucindezelwa nge thrombocytopenia, leukopenia. Ukwelashwa kweziguli overdosing ezenziwe control ushevu izikhungo.

"Colchicine" lisho ukuthini. Imiyalelo. intengo

Izindleko zomuthi - ruble 1450.