Izidakamizwa "Aklasta". imfundo

Izidakamizwa "Aklasta" analogue zomuthi ( "Veroklast", "Blaztera", "Zolendronat-Teva", njll) bayakwazi ukubambezela ukubhujiswa nezicubu namathambo. Zelendronovaya acid - ingxenye esebenzayo - likhona ekilasini bisphosphonates (zokwenziwa izinto ekuvimbeleni kwamathambo).

Izidakamizwa "Aklasta". incazelo

I nomuthi kukhishelwa ngesimo isixazululo ukumnika.

Ngemva kokuphathwa emthanjeni, ingxenye esebenzayo kwasakazwa the izicubu ithambo ngokushesha. Njengezinye bisphosphonates, zelendronovaya acid itholakala kakhulukazi ezindaweni ithambo resorption (Ukubhujiswa).

Ngu ekuvimbeleni ukubhujiswa, isithako esebenzayo akuphazamisi izakhiwo mechanical, inqubo kwetinhlavu kanye amathambo kwezinsalela namaminerali.

Izidakamizwa "Aklasta". Imiyalelo: Ubufakazi

Umuthi ezinqunyiwe ithambo isifo Paget sika (deforming osteitis), ukukhumuzeka kwamathambo postmenopausal (ukunciphisa amathuba waphuka kabuhlungu emgogodleni, kunawo wonke kanye nezinye amathambo futhi kuthuthukise amaminerali yabo kwabantu), nokuvinjelwa waphuka amathambo ngemva ukulimala emalungeni hip.

"Aklasta" lisho ukuthini. Ukufundiswa: umthamo lwemithi

Ngaphambi nokuphathwa izidakamizwa kuyadingeka ukuqinisekisa hydration elikhulu (amanzi ukugcwaliswa) umzimba. Lokhu kubalulekile ikakhulukazi isicelo yokwelapha isisu.

Ngokuba nokuvimbela waphuka ngemva kokulimala hip ekwelapheni kwamathambo postemenopauznogo izidakamizwa "Aklasta" Umhlahlandlela incoma kuphethwe ukumnika emthanjeni kanye ngonyaka inani angu ezinhlanu (kanye). Therapy kufanele kanyekanye thatha calcium supplements futhi kavithamini D.

Ngo ekwelapheni isifo Paget sika nomuthi emthanjeni "Aklasta" Kunconywa umsebenzi nokuyala umthamo angu amahlanu namashumi namamililitha i isixazululo aqueous esinikezwa ukumnika olulodwa emthanjeni usebenzisa uhlelo. Ukuphatha isikhathi - akukho ngaphansi kuka imizuzu eyishumi nanhlanu, ijubane kufanele kube njalo. Ngenxa yokuthi isifo Paget sika libhekene ukubhujiswa okuqhubekayo bone, zonke iziguli nale zokugula Kunconywa engayitholi imfuneko edingekayo vitamin D ne-calcium phakathi nezinsuku zokuqala ezingu eziyishumi emva ukumnika.

Ukuphatha lokuqala izidakamizwa "Aklasta" kubangela isikhathi eside ukuthethelelwa deforming osteitis. Okwamanje, ulwazi oluthile ukuze kabusha nokwelashwa kwezifo kungakephuzi Paget sika azitholakali. Nokho, ukwelashwa okunjalo kungenzeka, uma isiguli kokushelela. ukuthuthukiswa yesibili zokugula libhekene izici ezilandelayo: akukho ukuzinza of phosphatase ane-alikhali e serum, ukwanda Dynamics level yayo, futhi khona izimpawu zokwelashwa kwezifo Paget sika, ukubonakala ngemva kwezinyanga eziyishumi nambili isicelo "Aklasta" umthamo.

Umuthi is hhayi Kunconywa for iziguli umsebenzi ezinzima kwezinso.

Asebekhulile kanye neziguli kanye umsebenzi kwesibindi iziyaluyalu Isikali udinga ukulungiswa.

In the ukungabikho idatha ku ukuphepha kanye kusebenta "Aklasta" izidakamizwa iziguli ezingaphansi kweminyaka engu-nesishiyagalombili, bona umuthi hhayi iqondiswa.

Ngemva ukwethulwa izidakamizwa amathuba imfiva, zomkhuhlane syndrome, ukukhathala, ukuvuvukala ukuvela (ezingavamile), ukucobeka asthenia, Ukugodola. ukusabela njalo enqabayo kubhekwe aphathwe ikhanda, ukucobeka, isiyezi, iphika. Ngezinye izikhathi kungase imakwe paresthesia, nakwisyncope, liqhaqhazela, somnolence. Iziguli ingase ibe nomuzwa ubuhlungu emathanjeni emgogodleni. Mhlawumbe ukuthuthukiswa myalgia, arthralgia, dyspepsia, ukuhlanza, isicanucanu nezinye imiphumela emibi.

Izidakamizwa is contraindicated ngesikhathi lactation, hypocalcemia, ukukhulelwa, hypersensitivity.