"Ibuprom": imiyalo yokusetshenziswa, impendulo

izidakamizwa Nonsteroidal eqeda ukuvuvukala anesikhundla eqinile okuholela ezimakethe zemithi emhlabeni. La mathuluzi nethonya eziyinkimbinkimbi umphumela antipyretic, eqeda ukuvuvukala kanye analgesic emzimbeni womuntu. Omunye imithi enjalo kuyinto "Ibuprom". Ukufundiswa ulawula ke njengoba ikhambi ngempumelelo kakhulu ezihlukahlukene nezifo.

pharmacodynamics zomuthi

"Ibuprom" zimele phenylpropionic acid esuselwe. Mshini kusekelwe ukucindezelwa ithonya Cox umsebenzi (enzyme, eyandulela ka prostaglandins, nakho linqobe inqubo pathogenesis, ukuthuthukiswa emizweni buhlungu futhi febrile). Lapho nomuthi esivamile-non-abakhethayo okusithiyayo of cyclooxygenase, okusho "Ibuprom" ngokulinganayo kuvimbela umsebenzi kokubili isoforms of enzyme - .. Cox-1 kanye Cox-2.

Umthelela analgesic zomuthi "Ibuprom" yokusetshenziswa kubangela izindlela ezimbili - neuropathy emaphakathi. Pevy wabonakaliswa ngokungaqondile ngokusebenzisa okusithiyayo yenqubo ukukhiqizwa prostaglandin. Umthelela mshini yesibili (central) kuyinto ukucindezela isizukulwane prostaglandins ezindaweni ezimaphakathi kanye neuropathy we-NA. Ngenxa ekuphunguleni ukuvuvukala lipid samanje izinto physiologically asebenzayo incipha ukuzwela okuqonda receptor ezishukumisa zamakhemikhali. Ngo hypothalamus thermoregulation centre nokucindezela prostaglandin zamagama kuholela ukwehla kwezinga lokushisa komzimba uthi lapho okunomkhuhlane.

Ngaphezu kwalokho, "Ibuprom" amaphilisi (umsebenzisi A ukulungiselela iqukethe ulwazi ezifana) ngokwezinga elithile zivimbela wokuhlanganisa (kunenze nisondelane) ka-platelet.

Ukwakheka kanye nefomu wokukhulula izidakamizwa

Ibuprofen - main ingxenye esebenzayo "Ibuproma". Njengoba izingxenye asizayo kungenziwa ngokuthi crospovidone, Silicon dioxide, i-polyethylene glycol futhi eziningi izinto (gelatine, isitashi, amafutha yemifino, sucrose, futhi m. P.).

Amafomu lapho izidakamizwa ezinikezwa amakhasimende, ngaphezulu. Le mfundiso eyasungulwa ethi kungenzeka phama sachets e polyvinyl isitsha (amaphilisi 50) noma amanxeba okusha.

Kuye umthamo Isakhi esiyinhloko ekwakhiweni okushiwo "Ibuprome" (200 mg ibuprofen iphilisi ngalinye) noma nomuthi "Ibuprom Max '(400 mg ibuprofen). Kodwa akugcini lapho. On ukuhlukahluka ezifana "Sprint Ibuprom Capps" imfundo ekutshela ukuthi nomuthi ekhiqizwa e amaphilisi nge 200 mg asebenzayo izidakamizwa core endaweni ngayinye. "Ibuprom Ezingeziwe" banikeza iziguli amaphilisi, umthamo we ingxenye main ngamunye - 400 mg. On "Ibuprom itheku" manual uthi njengengxenye iphilisi elilodwa liqukethe 200 mg ibuprofen no-30 mg pseudoephedrine hydrochloride.

izinkomba

Incazelo zonke izimpawu izotholwa lapho sibona umphumela omuhle, kantsi sicuketse loku okuyiwa ezifana "Ibuprom" amaphilisi imfundo. Ukwakheka (analogs nomuthi ngempahla asebenzayo efanayo kuyodingeka cishe umphumela ofanayo), okusikisela ukuthi nomuthi inika yi omuhle ekwelapheni izifo ezifana izinkinga ukuvuvukala emgogodleni esiwohlozayo nezihlanganiso. Ayikho sokuqaqamba kwamalunga ngaphandle (samathambo onaso sibe, psoriatic), i-osteoarthritis, ankylosing spondylitis. Yabela "Ibuprom" izicubu zomzimba ezithambile ukuvuvukala uhlelo zemisipha kubangelwa umuntu elimele, radiculitis, bursitis, tendinitis. Ngaphezu kwalokho, i-nomuthi uyakwazi ukubhekana ne ikhanda futhi amazinyo, neuralgia, myalgia, ubuhlungu sifo ngo zezifo ezithathelwanayo namakhambi sokuvuvukala engenhla ipheshana zokuphefumula. Izisebenzi zezimo eziphuthumayo zisebenza ka ukuqoka "Ibuproma" ezimweni okunomkhuhlane ukwehlisa izinga lokushisa komzimba, nobuhlungu uzizwa ukulinganisela eyethile noma nokulinganisela odabuka ongaziwa.

"Max Ibuprom" imfundo manual uncoma ethatha khona izimpawu ezifanayo lapho umthamo edingekayo of nomuthi nakakhulu. "Ibuprom Ezingeziwe" ngeke naso singase siphumelele e izimpawu ezinjalo.

"Ibuprom itheku" (emagama lafanako - "Ibuprom Sprint Ofeleba") kuvame anqunyiwe ukunikeza isidambisa-zinhlungu, antipyretic futhi lithuthukise eqeda ukuvuvukala, kanye ukunciphisa ukuvuvukala lwamafinyila kwekhala kanye sinuses paranasal. Lokho, umuthi kuyoba ekwelapheni siyefana imikhuhlane, acute nezifo zokuphefumula futhi Umkhuhlane ephelezelwa ikhanda, umphimbo obuhlungu, imisipha, imfiva kanye ukuvuvukala nolwelwesi lwamafinyila kwekhala kanye sinuses paranasal.

izicelo ezingenzeka

imfundo 'Ibuprom "(amaphilisi) mathupha uncoma nika ngamunye isiguli ngasinye kuncike ukuziyisa phambili izimpawu zokwelashwa sifo. Isimiso ejwayelekile zomuthi - umthamo owodwa endaweni ivolumu mg 200 kuya ku-800 ngezikhawu 3-4 izikhathi ngosuku. Ezigulini abasebasha umthamo is akhethiwe kuye esisindo - 20-40 mg amakhilogramu esisindo ngasinye (lokhu ivolumu nsuku zonke), ihlukaniswe izikhathi eziningana usuku lonke. ukwelashwa ngokuvamile Uthatha 2 kuya 3 amasonto. esiphezulu umthamo ibekezelelwe ngelanga i isiguli esingumuntu omdala - 2.4 g wamukela phakathi noma ngemva kokudla futhi beyihlanza kokuncinyane okusamanzi. Hlukanisa ithebhulethi zibe izingxenye engathandeki.

"Max Ibuprom» kukhona ngokuzimela ukudla neziphuzo-ke kudinga elizwakalayo yamanzi. On ingxenye yokuhlukanisa iphilisi engathandeki.

Ngokuqondene "Sprint Ibuprom Capps", wabe esekhonza iminyaka iziguli engaphezu kwengu-12 ubudala umthamo owodwa kuyinto 1-2 amaphilisi zonke 4-6 amahora ngezikhathi. Yimikise ukudla ngesikhathi noma ngemuva. Kubantu abadala ngokukhethekile ukhetha umthamo akudingekile, ngaphandle amacala ukwehluleka okusobala kwezinto nokusebenza kwezinso nesibindi.

"Ibuprom Ezingeziwe" imfundo Kunconywa ukuthatha 1 capsule njalo emahoreni 4 (ukhuluma ngani iziguli abaneminyaka engaphezu kuka-12), kodwa hhayi ngaphezulu kuka-3 amaphilisi ngosuku. Thatha imithi emva kokudla, musa ukuhlafuna. Ukuze ezigulini esezikhulile ngokukhethekile ukhetha umthamo akudingekile.

"Ibuprom itheku" ezithathwe ngaphambi ukudla 1-2 amaphilisi kanye ukugeza phansi ngamanzi. Imvamisa - njalo emahoreni 4-6. I sangemihla kuvunyelwe ukuba baphuze amaphilisi 6.

Izimo lesi sidakamizwa "Ibuprom"

"Ibuprom" (amaphilisi) usebenzisa umyalelo liyakwenqabela abangenawo hypersensitivity linyuke laba ngu-ibuprofen noma iyiphi izithako isesekeli. Ingamukeleki isabelo nomuthi ngoba iziguli wokugaya ukudla ipheshana izilonda imvelo erosive-ulcerous (ikakhulukazi esigabeni acute). Futhi akuvumelekile ukwelashwa "Ibupromom" ebukhoneni aspirin triad , futhi kwezinye izifo emsipheni optic. Ukwehluka kwi-operation hemopoietic uhlelo nazo ngesisekelo non-ukusetshenziswa kwanoma iyiphi amathuluzi kusukela iqembu NSAID. Hhayi wayekwenza Inhloso yalesi izidakamizwa iziguli lapho ibhalwe ukushayisana nezinso isibindi.

Akwamukelekile futhi Isicelo "Ibuproma" kanye neminye imithi kusukela iqembu non-steroidal.

Ngokuqondene izidakamizwa 'Ibuprom Max "amaphilisi yokusetshenziswa unqabela ngaphansi nezinkinga ezifanayo, njengoba enza" Ibuprom ".

"Ibuprom Ezingeziwe", ngaphezu zonke Izimo ngenhla echazwe, akusho libeke khona oluhambisana diathesis in iziguli enganele umsebenzi inhliziyo. Wena ubuye awukwazi ukuthatha lesi izidakamizwa ayephuli amanzi emzimbeni sokucasuka ukuhlanza, ukukhishwa isisu noma alanele ukusetshenziswa uketshezi.

Esikhathini izidakamizwa "Ibuprom itheku" konke ngaphezu Izimo esinqunyiwe. Ngaphezu kwalokho, alisetshenziswa isifuba somoya, isifo sikashukela, yegilo (giperterioz) amazinga aphakeme ama-hormone. Is contraindicated phambi iziguli pheochromocytoma (izimila adrenal ezicutshini), Hyperplasia (adenoma) ka wendlala.

ukuphelisa ituthuko engakalungi

"Ibuprom" njengoba ibekezelelwe? Manual iqukethe ulwazi lungaba ezinye izigameko ezingezinhle ezavela kusukela izinhlelo ezahlukene kanye izitho seziguli ezithola izidakamizwa. Inani elikhulu yezimpendulo ukusetshenziswa ama-NSAID siyenzeka kusukela pheshana emathunjini. Iziguli ukhulume isicanucanu, ukuhlanza, ukungakhululeki epigastric, sokuzincisha kanye nokuthuthukiswa izilonda erosive ulcerous we lwamafinyila we ipheshana wokugaya ukudla.

CNS side effects zivame waphawula ikhanda, isiyezi, ukuyaluza, kwezinso ubuthongo nokubukwayo bezibona izinqubo. Okungenzeka ohlangothini ukusabela krovetvoryaschey uhlelo ekwamukelweni nomuthi okwesikhathi eside isikhathi - anaemia, thrombocytopenia, agranulocytosis.

Kunezindlela ezihlukahlukene komzimba nezinto "Ibuprom". Tablets (umsebenzisi iqukethe ulwazi) Kungenzeka avuse amawala, edema angioneurotic. Ezimweni ezingavamile kakhulu kungadala meningitis aseptic (the Lesi sifo siphatha kakhulu kule ukuphendula abantu abanezifo sokuhlasela kwamasosha omzimba), bronchospastic syndrome. Ngenxa yokuthi wabona ukuthi lendawo iziguli ekushoyo ukuzwa esivuthayo ukuluma kwesikhumba, mayelana ukuminyana.

"Ibuprom itheku", ngaphezu kwawo wonke ngenhla ohlwini, kungadala ukuthuthukiswa dyspnea, tachycardia, ephakeme blood pressure, hyperhidrosis.

Ukweqiwa ngokweqile: Imithelela

Endabeni ukweqisa izidakamizwa izidakamizwa ezifana "Ibuprom" futhi "Max Ibuprom" imfundo manual ibika ukuthuthukiswa okungenzeka isicanucanu nokuhlanza, ubuhlungu epigastric. Futhi, uma ubhekene nesimo esinjena kungenzeka ukozela, wazizwa ikhanda nesiyezi, kungehlisa umfutho wegazi futhi arrhythmias. Ezimweni ezimbi kakhulu izimpawu zibonakala lactic umzimba kungenzeka nokulahlekelwa ukwazi nge kahle umsebenzi zokuphefumula.

Ezimweni ezinjengalezi ke Kunconywa esiphuthumayo lavage esiswini kanye nokuqokwa ukwelashwa lingaze. Kwenziwe enterosorbents ngomlomo. Writhing syndrome likhishwa nge "Diazepam", "lorazepam".

Nge ukweqisa izidakamizwa of "Ibuprom Sprint Capps," ngaphandle bonke ngenhla, kukhona amathuba disorientation, ukuquleka, ikhoma. Okungenzeka isibindi ukungasebenzi. In iziguli somoya, kungaba kubi kakhulu lesi sifo.

ukusetshenziswa isikhathi eside izidakamizwa "Ibuprom itheku" kungabangela ushintsho sokugembula egazini, njenge hemolytic anemiya (nokwahlukana ngcono amangqamuzana abomvu egazi), granulocytopenia (nokuncipha inani granulocytes), thrombocytopenia (encishisiwe platelet count).

Yini okufanele banake?

"Ibuprom" Umhlahlandlela incoma zithathwe ngokuqapha labo Uhlanganise isifo sesibindi, isifo sezinso, ezingamahlalakhona yokumelwa yinhliziyo. Uma ngaphambi kokuqala ukwelashwa isiguli inezimpawu of dyspepsia, noma isiguli nje wahlinzwa, kudingeka futhi ukuqala ukwelashwa "Ibupromom" ngokucophelela okukhulu. A umlando ulwazi ukopha kwanoma yiluphi uhlobo izifo wokugaya ukudla, ukubonakaliswa nomzimba, kwezidakamizwa kuhlobene impatho-nonsteroidal eqeda ukuvuvukala, kufanele futhi kube ithuba qikelela ukuthi isimo isiguli.

Ukuze kugwemeke izingozi, kubalulekile e isicelo "Ibuproma" ngokuqhubekayo nokuqapha umsebenzi kwezinso nesibindi, neuropathy igazi isithombe.

Futhi "Ibuprom" futhi "Max Ibuprom" imfundo akuyona Kunconywa ukuba isetshenziswe 3 senyanga yokukhulelwa. Ngo 1 no-2 trimesters ukusetshenziswa NSAID ulungisiswa kuphela ezimweni lapho kulindeleke nomphumela omuhle ngoba unina bulingana engaba mibi ingane.

Ibuprofen - main ingxenye esebenzayo "Ibuproma" - ngemithamo emincane excreted ku ubisi lwebele, nokho ngenxa yosizo ubuhlungu nemibandela okunomkhuhlane isicelo yayo ngesikhathi lactation kungenzeka. Nokho, uma kukhona umbuzo yokwelapha eside ngosizo "Ibuproma" noma isidingo ukuthola imithamo emikhulu kufanele uxoxe nodokotela wakho umbuzo yokwenqaba ukuncelisa.

Ukusebenzisa "Ibuproma itheku" esikhathini esesibelethweni okukhulelwa kanye nokuncelisa ibele ngokuvamile contraindicated.

Ukuxhumana nezinye izidakamizwa

Nanoma yiluphi uhlobo "Ibuproma" ( "Ibuprom Max", "Sprint Ibuprom Capps," "engaphezulu Ibuprom") incwadi yeziyalezo unqabela parallel antihypertensives futhi isisu ezifana furosemide, hydrochlorothiazide, njengoba umphumela zabo zokwelapha kungenziwa kakhulu ziyancipha.

Ukusetshenziswa "Ibuproma" esihambisana antiplatelet futhi inhibitor ukukhetha serotonin kwandisa ingozi ukopha LCD. Ngaphezu kwalokho, kuyinto akwazi ukwandisa NSAID glycosides okuqukethwe e-plasma, futhi kanjalo, kubangele exacerbation of congestive yokumelwa yinhliziyo. "Ibuprom" ukwandisa izenzo ku umzimba womuntu anticoagulants. Ngenxa yalesi sizathu, kubalulekile ukuqapha njalo coagulation imingcele, t. Ukuze. Ibuprofen iyehlisa platelet wokuhlanganisa.

Ngo isicelo ehambisana nezidakamizwa lithium futhi "MTX" kakhulu ukwandisa okuqukethwe kwalezi izinto oketshezini olungenambala lwegazi. Tandem nge cyclosporine nephrotoxicity phambili nokwanda lakamuva.

Inhlanganisela "Ibuproma" nge amalungiselelo digitalis (digitalis) kungabangela ukuthuthukiswa arrhythmias inhliziyo. Noma kungathatha lokhu NSAID esihambisana acetylsalicylic acid (aspirin), njengoba kukhona kungenzeka ohlangothini inzuzo negative ukubonakaliswa.

Inhlanganisela quinolone ejenti elwa namagciwane, futhi noma iyiphi NSAID (futhi "Ibuproma" kuhlanganise) kwandisa ingozi nokuquleka. Inhlanganisela ngemithi yokwelapha, njengoba "Zinovudin" kwandisa ingozi haemarthrosis kanye hematoma e iziguli ezinegciwane lesandulela-ngculaza.

Imibono iziguli ngemithi

PVA Nonsteroidal - lawa amalungiselelo sina ngokuvamile anhlobonhlobo imiphumela. Ngakho-ke, ukusabela iziguli zindlela kukhona njalo kokubili isiqondiso emihle nemibi. Iyathinteka futhi "Ibuprom".

Kwenqwaba yabantu abaphuza umuthi, yayijabulela umphumela wakhe. Ubuhlungu ngokushesha kuphele futhi isikhathi eside ngokwayo akuhlanganisi. Umuthi okuye kungase kutholakale esikhathini okubuhlungu, ikhanda kanye myositis, neuralgia futhi myalgia ngesikhathi.

Ngesikhathi esifanayo, kuneziguli abangajabule nethonya lesi sidakamizwa "Ibuprom". Ukufundiswa uthi ukuthuthukiswa ngokushesha umphumela analgesic, kodwa abathengi abaningi musa ziye zazizwa isenzo yalesi izidakamizwa. Ngaphezu kwalokho, abaningi bakhononda of ukusabela ezingezinhle ezifana isicanucanu nekhanda.

Iqembu elikhulu kubantu ukhononde ngokuthi "Ibuprom" singasuki kinid amazinyo ngokuphelele. Nakuba kulesi simo-ke akudingekile ukuthi ukuthi izidakamizwa kubi. Iqiniso lokuthi, isibonelo, pulpitis acute ngeke kusize noma iluphi usuku ngaphandle umjovo ngqo ushingamu amaphilisi ezinhlungu. Endabeni ukunkenketha "Ibuprom" - kuba ithuba ngokushesha ngangokunokwenzeka ukuze uthole udokotela wamazinyo, ngaphandle uhlangabezana ubuhlungu obunzima.

Kunoma ikuphi, ama-NSAID - ke obezvolivayuschie kanye isizukulwane esisha ejenti eqeda ukuvuvukala, ngempumelelo endaweni ezihlukahlukene kakhulu ezingenzeka ezibhekwa pathologies. Lona umbono iningi abathengi kanye bezempilo.