"Exelon" (patch): intengo, ukubuyekezwa, futhi yokusetshenziswa

Izifo ezihlala kepha wesabeka njengezimpi Alzheimer, ngeshwa, kuze kube manje, kukhona cishe kungenakwenzeka ukwelapha. Noma kunjalo, kukhona imithi ethile kungaba ngendlela ephawulekayo inciphise ukuqhubeka iziyaluyalu isimiso sezinzwa. nomuthi "Exelon" libhekisela leli qembu. Isichibi kulula ukuyisebenzisa futhi unikeza imiphumela kuhle, okwenza kube ethandwa e imithi yesimanje. Ngakho-ke yini ingxenye izidakamizwa nokuthi kuyithinta kanjani umzimba? Kungakanani band zokwelapha? Uyini lwemithi yokwelapha? Izimpendulo zale mibuzo esinesithakazelo kuyo iziguli eziningi.

Ifomu ukukhululwa izidakamizwa ekwakhiweni kanye nencazelo

Ukulungiselela "Exelon" - isichibi, okuyinto okuthiwa transdermal uhlelo zokwelapha. Ekhemisi, ungathenga isichibi okusaqanda encane, emhlophe substrate beige. Imininingwane surface area 5 amasentimitha sikwele.

The main asebenzayo izidakamizwa ketshezi kuyinto rivastigmine. Kukhona nezimagqabhagqabha equkethe 9 futhi 18 mg le ngxenye. Lapho egqoke imithi patch kancane kancane uwela ngaphakathi emzimbeni - emini nje phezu umthamo eligcwele (4.6 kanye 9.5 mg, ngokulandelana).

Ukulungiswa iqukethe ezinye adjuvants, ikakhulukazi acrylic copolymer, alpha-tocopherol, butyl methacrylate futhi methyl methacrylate. Ngaphandle ungqimba ingcina yakhiwa uwoyela abicah kanye copolymer abicah.

izakhiwo kwemithi zomuthi

Isakhi esiyinhloko le rivastigmine izidakamizwa - a inhibitor abakhethayo kobuchopho cholinesterase. Lokhu kwaziswa siyehla izinqubo nolokubhujiswa acetylcholine, oveza ezisebenza izinzwa beqinile, futhi kuthuthukisa izinhlaka zokuxhumana zobuchopho ukudluliswa izinqubo.

Ukusebenzisa izidakamizwa kungandisa amazinga acetylcholine e cortex cerebral futhi hippocampus, okuholela ngcono ukudluliswa cholinergic. Njengoba komqondo Alzheimer futhi ukwehla imisebenzi engqondweni yethu zobuchopho ezihlobene ngokuyinhloko ukuntula acetylcholine, umuthi empeleni kusiza kujwayeleke isimiso sezinzwa. Ngaphezu kwalokho, kukhona ubufakazi ngalo ukuqinisekisa ukuthi izidakamizwa siyehla izinqubo zamagama we-beta-amyloid iphinde ivimbele kumiswa amyloid zingcwecwe, okuyinto ungomunye kuyizimpawu Alzheimer.

izinkomba

Ngo inqubo yokwelapha yesimanje, umuthi isetshenziswa kaningi, kodwa izinkomba ukwamukelwa yayo likubeka ngokucacile - kuba okuncane komqondo Alzheimer. Kulesi isicelo se-patch kungenzeka kokubili ukuba khona isifo noma okusolwa lapho ukuthuthukiswa yayo (kuleli cala, kuyasiza ukubambezela lokhu kuzibonakalisa isifo).

Khonka "Exelon": isitatimende

Yiqiniso, iziguli eziningi unesithakazelo imibuzo mayelana nendlela ukusebenzisa ithuluzi kahle. Akunakusetshenziswa akufanele ukuyisebenzisa ngaphandle kwemvume. Kuphela udokotela emva ukuxilongwa okujuli- isiguli unelungelo ukuncoma patch "Exelon". Manual iqukethe izincomo kunesidingo.

Ngokuvamile, ukwelashwa isiqalisile nge imithamo ezincane, okungukuthi patch umzimba ukuhlinzeka 4.6 mg izidakamizwa esebenzayo ngosuku. Uma izidakamizwa amasonto ambalwa is kahle ikubekezelele umzimba, kudala kabi imithi emzimbeni futhi uwohloke umthamo senyuselwa 9.5 mg rivastigmine ngosuku. Isikhathi yokwelapha kunqunywa kuphela ngudokotela - yokwelashwa ingatholakala eyenziwa izinyanga eziningana, ngezinye izikhathi ngisho iminyaka, uma izidakamizwa kuye kwaba nomphumela omuhle. Ngezinye izikhathi isichibi ungayithola enye by amaphilisi noma imijovo, "Exelon" Ukuxazululwa noma eminye imithi ethile.

Kuleso simo kumele uphazamise ukwelashwa izinsuku ezimbalwa noma ngaphezulu, kabusha uqale ukwelashwa futhi kudingeka umthamo ubuncane ketshezi asebenzayo.

Ingabe kukhona Izimo?

Kukhona ezinye contraindications ukusetshenziswa "Exelon" izidakamizwa. Isichibi akufanele asetshenziselwe iziguli hypersensitivity kuya rivastigmine noma omunye ingxenye ekwakhiweni.

Ngokunakekela ithuluzi zaphathwa kubantu abaphethwe isifuba somoya noma esinye isifo obstructive umgudu wokuphefumula. Ukuze Izimo isihlobo futhi zihlanganisa iziguli nge nezici ezithile ukuze pheshana urinary ukuvimbela kanye nokugoqana komzimba. kwenziwe ngokucophelela ukwelashwa kweziguli kahle isibindi umsebenzi, kanye neziguli isisindo isidumbu 50 kg.

Abantu abaningi bayazibuza ukuthi kungenzeka ukusebenzisa phakathi nokukhulelwa kanye lactation imithi "Exelon"? Isichibi ezinqunyiwe kwabesifazane abakhulelwe uma ngiphoqelekile ngempela, njengoba izifundo ezifanele, okungaqinisekisa ukuthi harmlessness noma, kunalokho, ingozi lokhu kusho umzimba kamama kanye nengane ingakamiswa kwenziwe. Uma kukhona nesidingo sokufaka isicelo isichibi ngesikhathi lactation, ukuncelisa umntwana kufanele ayeke.

Okungenzeka imiphumela engemihle patch

Ingaba khona nanoma yiziphi izinkinga ngesikhatsi ukwelashwa nge patch "Exelon"? Izibuyekezo lodokotela abonisa ukuthi ukusabela ezingezinhle zenzeka kuqhathaniswa akuvamile, ikakhulu lapho uqhathaniswa yokwamukela ifomu tablet zomuthi. Noma kunjalo, ukwephula zingenzeka, futhi uhlu lwabo kufanele ufunde:

• Therapy ezivamile kuholela ukuhlukumeza wokugaya ukudla, okuyinto kuhambisana isicanucanu nokuhlanza, ubuhlungu besisu, uhudo, dyspepsia. Kakhulu akuvamile ngesikhathi yokwelapha nezilonda emathunjini, ubuchopho esidalwa yizilonda emathunjini sibe we ulwelwesi lwamafinyila.
• Kungase kube ukusabela abanye phezu ingxenye isimiso sezinzwa, kuhlanganise ukukhathazeka, delirium, yokufikelwa, ubuhlungu bekhanda, ukudangala, ukuhhema.
• Ezinye iziguli kubika ezincane iguliswa isikhumba ukusabela, kuhlanganise ukuqubuka futhi ububomvu. Ngezinye izikhathi esikhundleni usimende obandayo ukuthuthukisa erythema noma ukuvuvukala.
• On the ingxenye esimiso senhliziyo nemithambo yegazi kungenzeka ukuhlukumeza kwegazi cerebral, bradycardia.
• Phakathi kwezinye kungenzeka emibi ibandakanya sokuzincisha ukudla, kwesisindo, ukukhathala, imfiva, ukuqwasha, pheshana urinary ukutheleleka.

Uma kukhona ukwephulwa qiniseka bonana nodokotela wakho kuqala. Mhlawumbe isiguli izidakamizwa akukalungi, futhi kungenzeka kudingekile kuphela ukuze ulungise umthamo.

Overdose futhi izimpawu zaso

Ingabe ukweqisa izidakamizwa kungenzeka lapho izidakamizwa "Exelon" (patch) asetshenziswa? Iziyalezo yokusetshenziswa aqukethe ulwazi mayelana lokuthi amacala anjalo ezibikwa akuvamile futhi ngokuvamile akuzona eziyingozi kakhulu. Izimpawu ukweqisa izidakamizwa ngephutha - ukwanda wegazi, isicanucanu, ngezinye izikhathi ukuhlanza, futhi babone izinto ezingekho. Kakhulu akuvamile waphawula bradycardia noma nakwisyncope. umuthi othile ngokuvamile akudingeki. Ngemva ukuqedwa emzimbeni ubuyela evamile phakathi kwezinsuku ezingu-1-2.

Zikhona analogs ngempumelelo?

Ngokuqinisekile, akuwona wonke umuntu esifanelana lokhu izidakamizwa. Ngingaba esikhundleni into izidakamizwa "Exelon"? analogue yayo, yebo, khona, kodwa ukukhetha ilungelo can udokotela kuphela.

Kaningi, iziguli ezinemishini kokutshelwa ngokukhubazeka kwengane ezinqunyiwe "Altsenorm". Imiphumela emihle ingatholakala usebenzisa izidakamizwa ezifana "Hloprotiksen" futhi "Memantine". Futhi ukubambezela ukuqhubeka iziguli Alzheimer isifo bavame ukutusa ngokuthatha izidakamizwa "Noodzheron". Kodwa-ke Kuyaphawuleka ukuthi zonke amathuluzi ngenhla ayatholakala amaphilisi, amaphilisi noma izixazululo umjovo. Kwezinye izimo, isichibi kuyinto zibelula ukuyisebenzisa.

Kungakanani band zokwelapha?

Yiqiniso, i-iziguli eziningi, impikiswano ebalulekile kuyinto izindleko umuthi. Ngakho malini izobiza isichibi "Exelon"? Intengo kuzoncika ezintweni eziningi. Ikakhulukazi, isidingo acabangele umkhiqizi, umthamo we ketshezi esebenzayo, nokunye. D. Okufakiwe 30 nezimagqabhagqabha kubiza ruble mayelana 3600-4500. Ngokuvamile, leli nani zomuthi kwanele ngenyanga. By the way, mangisho ukuthi eminye imitholampilo lo muthi mahhala, nge kadokotela iziguli isifo i-Alzheimer (buza lolu lwazi kudokotela wakho).

Khonka "Exelon": Izibuyekezo

Kwezinye izimo, ulwazi abaluleke kakhulu ingatholakala ngokuxhumana imibono kanye nakho iziguli kakade kwadingeka isikhathi ukwelashwa. Ngakho ukukhuluma mayelana izidakamizwa "Exelon"? Izibuyekezo ingxenye enkulu akhayo. Ochwepheshe ukuthi ukusetshenziswa ngokufanele imithi esiza ngempela ukuqeda ezinye zezimpawu futhi sithuthukise isimo lesiguli.

Sisebenza kahle kangakanani isichibi "Exelon"? Nobufakazi abonisa ukuthi ngempela imiphumela emihle ukuphi. Kwezinye izimo, le ukuqhubeka kwesifo kungenzeka ukubambezela i-isikhathi esingangonyaka noma ngaphezulu. Noma kunjalo, kufanele uqonde ukuthi i-Alzheimer - isimo sibucayi kakhulu futhi ikhambi namuhla alikho. Ngakho-ke, akufanele kuthathwe njengoba isiqinisekiso patch yokutakula, ngoba Ngeshwa akunakwenzeka.