"Kaffetin Cold": yokusetshenziswa, ukwakheka, analogue

Uyini elaphe "Kaffetin Cold"? Ukwakheka kanye izici izidakamizwa kuzoxoxwa ngezansi. Siphinde ngikuxoxele kanjani ukuthola wathi nomuthi futhi ngasiphi izifo ke lenikiwe.

Ubujamo, emabhokisini Ukwakheka

I nomuthi "Kaffetin Cold" is ithunyelwa ifomu tablet futhi simise oblong biconvex (umugqa ngakolunye uhlangothi) camera blue film-camera. Basuke ibekwe endaweni ibhamuza perforated, ehlanganisa aluminium ucwecwe futhi ezintathu ungqimba ifilimu esobala, okuyinto ebhokisini ibhokisi.

Equkethe izidakamizwa ngokuthi "Kaffetin Cold"? Ukwakheka lokhu izidakamizwa:

• dextromethorphan hydrobromide (15 mg);
• pseudoephedrine hydrochloride (30 mg);
• ascorbic acid (60-62 mg) njengoba granulate, equkethe-97% ka-vitamin C, futhi 3% hydroxypropyl methylcellulose;
• paracetamol (500-555 mg) ngesimo granules ehlanganisa u-90% we ketshezi, kanye izingxenye asizayo njengoba prozhelatinizirovanogo isitashi, stearic acid kanye povidone.

Kufanele kuqashelwe ukuthi le "Kaffetin Cold" njengoba izithako engeziwe zihlanganisa magnesium stearate, Silica Colloid, microcellulose, sodium croscarmellose futhi talc.

Film enamathela we nomuthi wenziwe udayi oluhlaza okwesibhakabhaka, macrogol, ama-titanium dioxide, polyvinyl utshwala kanye talc.

I kwemithi zomuthi

Yini izakhiwo nobuntu izibhebhe 'Kaffetin Cold "? Ukufundiswa uthi ithuluzi uyakwazi ukubonisa analgesic kanye izakhiwo antitussive.

Lo mshini wezenzo we nomuthi ngenxa yokubakhona therein yezingxenye ngenhla. Cabangela izici zawo manje:

• Paracetamol kuthinta umzimba futhi obezbolivayusche zharoponizhayusche. Lo msuka uyakwazi ukuvimba Cox ku CNS. Lokhu kwenzeka ngokusebenzisa imiphumela ngqo ku ubuhlungu izikhungo kanye thermoregulation.

I lolwehlukanisa le isithako ama-NSAID ukungabi ingqikithi umphumela anti-inflammatory. Paracetamol akusho obulimaza ipheshana wokugaya ukudla futhi akuphazamisi umzimba amanzi-usawoti, njengoba akusho esilimaza synthesis prostaglandins ezicutshini neuropathy.

• Yini enye engingabuye izidakamizwa emangalisayo "Kaffetin Cold"? Isizinda pseudoephedrine uyakwazi ukunikeza umthelela tapered ezikebheni ezisesandleni mucosa we pharynx futhi acinene ingaphakathi. Futhi, lesi sici kakhulu kunciphisa zokuzikhukhumeza, ngaleyo ndlela kuncishiswe uketshezi kule nasopharynx futhi kulula acinene ukuphefumula.
• Ascorbic acid kuqukethwe imoto, nokuvulwa Vitamin C ukuntula, okuyinto sivame ukuba phakathi imikhuhlane.
• Dextromethorphan kuthinta isikhungo ukukhwehlela. Kunciphisa ngobucayi isifuba esomile ukuthi lihlotshaniswa ukucasuka we nasopharynx lwamafinyila for imikhuhlane.

izakhiwo kinetic

kanjani ukumuncwa lesi sidakamizwa "Kaffetin Cold"? Izibuyekezo Ochwepheshe abonisa ukuthi ukumuncwa iningi paracetamol kwenzeka emathunjini amancane. Ngakho lokuhlushwa yayo ephakeme kunazo zonke e-plasma yegazi siyenzeka kungakapheli imizuzu 30-90 emva ekuphathweni ngomlomo.

Umzimba into umbuzo (mayelana 90-95%) kwenzeka esibindini. Ngenxa yalokho, ama-derivatives ngasebenzi akhiwa (ngenxa yokusabela conjugation nge glucuronic acid sulfate). Zingaba nethonya ivimbela ohlelweni enzayimu esibindi, kanye ukuyithukuthelisa ukufa amaseli.

Ingxenye-ukuphila yabaphathi kusuka abantu kuyinto amahora 1-4. paracetamol ezibonisiwe futhi metabolites yayo nge nezinso. Lapho esegugile kungenzeka ukwehla imvume izidakamizwa, kanye ukwanda isikhathi isigamu-nokuphila.

Ngemva dextromethorphan wangena emzimbeni womuntu, waba cishe ngokushesha angena egazini. Ubuningi eliphakeme kwalesi sakhi plasma siyenzeka emva kwemizuzu 130 ngemva ephethe izibhebhe. Le into is akheka esibindini. metabolites bakhona excreted ku umchamo.

Pseudoephedrine futhi ngokushesha angena kwegazi emva ekuphathweni ngomlomo. Ubuningi eliphakeme we ketshezi kufinyelelwa ngemva kwamahora angaba ngu-2 a plasma. Isigamu-ukuphila pseudoephedrine imayelana 6 amahora. It is akheka esibindini (ingxenye), ngaleyo ndlela ukwakha esuselwe kamuva excreted ku umchamo.

Ngokuqondene acid ascorbic, it is kahle ugxile kusukela pheshana emathunjini bese ngokushesha ukusatshalaliswa zonke izicubu. Le ngxenye is reversibly oxidized ukuba degidroksiaskorbinovoy acid. Kulokhu ezinye Vitamin C wathola umzimba, akheka e element ngokuthi ascorbate-2-sulfate.

Excreted ketshezi ivela umchamo.

ubufakazi

Izidakamizwa "Kaffetin Cold" lisetshenziswa ekwelapheni lingaze Umkhuhlane kanye imikhuhlane, kuhlanganise izindawo elivela kuzo izimpawu ezinjalo ezingathandeki ezifana ikhanda, isifuba esomile lapho ubuhlungu bemisipha, ubuhlungu emphinjeni, amakhala yisisu, imfiva, sinuses acinene futhi impumulo .

Izimo

Izidakamizwa "Kaffetin Cold" ayikwazi ukusetshenziswa in iziguli kwale mibandela elandelayo:

• ukhulelwe;
• Hypersensitivity emuthini;
• yokuntuleka azalwa naso glucose-6-phosphate dehydrogenase;
• umfutho wegazi ophakeme, isifo senhliziyo, pectoris angina;
• iziyaluyalu inzima izinso kanye kwesibindi, ukusha kwesibindi;
• reception ngesikhathi esisodwa antidepressant, monoamine oxidase inhibitor nezidakamizwa ezisetshenziswa ekwelapheni antiparkinsonian;
• lactation;
• yobudala engu-12.

I siqaphe umuthi Kunconywa:

• arrhythmia;
• hyperbilirubinemia ingozi;
• i-hyperthyroidism;
• ukusha kwesibindi kohlobo viral;
• Hyperplasia we endlaleni engasesinyeni;
• ukuluthwa utshwala;
• ngifundise ngesifo sikashukela;
• obstructive yamaphaphu isifo imvelo ezingamahlalakhona;
• isifuba somoya bronchial;
• ukukhathala.

Nomuthi "Kaffetin Cold": yokusetshenziswa

Kubhekwe kuphela kusho senzelwe abaphathi ngomlomo.

Isikali abadala nentsha engu-12 ubudala 1 ithebhulethi kane ngosuku. Ngesikhathi ovunyelwe ukusebenzisa hhayi ningi than amaphilisi 2.

Isikhawu esiphakathi ukusetshenziswa imithi akufanele kube ngaphansi kuka-4 amahora. Ngakho umthamo nsuku zonke zomuthi kumele singeqi amaphilisi 8.

Uma kukhona imfiva isikhathi esingaphezu kwezinsuku ezingu-3 ngemuva Ukuqalwa okwelashwa, kanye isifuba esomile iqhubeka izinsuku 5, khona-ke kufanele ngokushesha ufune usizo lwabezokwelapha.

uhlangothi imihlola

ukusabela ezingezinhle ngemuva kokuthatha izidakamizwa ngaphansi ukucatshangelwa kungase kubonakaliswe ngezindlela eziningi, kusukela cishe zonke izinhlaka futhi izinhlelo zomzimba:

• isicanucanu, nomlomo owomile, ubuhlungu epigastric;
• somnolence, ukuyaluza, ukucasuka, isiyezi;
• yokungezwani komzimba njengoba pruritus, ukuqubuka, angioedema, urticaria;
• anda blood pressure, ukuthuthukiswa tachycardia;
• kwegazi, thrombocytopenia, agranulocytosis, pancytopenia;
• umphumela nephrotoxic, okuyinto kubonakala colic kwezinso, ukuthuthukiswa necrosis papillary noma nephritis interstitial.

Ukweqisa izidakamizwa imithi

Ngezinye ngemithamo ephakeme izidakamizwa, isiguli bangezwa isicanucanu, tinnitus nobuhlungu endaweni esiswini. Futhi nge izidakamizwa ngokweqile imithamo isikhumba lesiguli iba ugodo, liyophuma nomjuluko kunethonya elisezingeni elifanele iba palpitations njalo.

Kuchazwe zidinga ngamanzi ngokushesha esiswini. Futhi, umthamo zaphathwa isiguli ocushiwe carbon, olufanele isisindo nesineke. Uma kudingeka, lokhu kwelashwa lingaze.

ukuxhumana

Paracetamol ebulilini kwandisa imithelela anticoagulants.

Ukusetshenziswa kwezidakamizwa okuyizinto inducers ka microsomal namachibi (isb, "Phenytoin", i-ethanol, barbiturates, "rifampicin", "Phenylbutazone", tricyclic antidepressant), ama-ejenti hepatotoxic kakhulu kwandisa kumiswa asebenzayo imikhiqizo hydroxylated umzimba we-paracetamol, okuyinto kwandisa amathuba ezinzima ukudakwa Development , kuhlanganise yokwamukela kwafakwa isilinganiso esincane semithi izidakamizwa.

ukusetshenziswa isikhathi eside barbiturates kunciphisa ukusebenza kahle we-paracetamol.

Inhlanganisela paracetamol no salicylates kwandisa nengozi yokuba nesifo somdlavuza kwesinye noma izinso.

ukusetshenziswa isikhathi eside NSAID futhi paracetamol ikhuthaza nesenzakalo analgesic nephropathy, kwezinso necrosis papillary futhi litjhidele ekupheleni-esiteji ukwehluleka kwezinso.

Ukusebenzisa "diflunisal" kuholela umphumela hepatotoxic zomuthi.

ukusetshenziswa ngesikhathi esisodwa pseudoephedrine namanye amanxusa sympathomimetic kungase kube nomthelela okuvela kuyo imiphumela anobuthi, kanye nomphumela okufakiwe. Inhlanganisela le ngxenye nge monoamine oxidase inhibitor ngokuvamile kuholela ukuthuthukiswa esibucayi abanomfutho wegazi ophakeme. Kule ndaba, ukusetshenziswa kwezidakamizwa olucutshungulwayo avunyelwe akukho ngaphambi kwezinsuku ezinga-14 ngemuva kokuthola monoamine oxidase inhibitor inqanyuliwe.

ukusetshenziswa ngesikhathi esisodwa "Propranolol" sithuthukisa umphumela pressor okungukuthi pseudoephedrine. Ngaphezu kwalokho, uma usebenzisa i-yokugcina kungancipha umphumela hypotensive amathuluzi ezifana "methyldopa", "reserpine", "mecamylamine" futhi t. N.

ulwazi oluthile

Manje uyazi ukuthi lena izidakamizwa ngokuthi "Kaffetin Cold."

Methamphetamine - kuyinto methamphetamine. Kuyinto ivuselela futhi kubangela kwencika okusezingeni eliphezulu mayelana nokungokomunye ihlobene izidakamizwa. Abanye abantu bazama ukuletha le ngxenye zomuthi "Kaffetin Cold." Isikhala zomuthi ekhiqizwa ngezindlela ezahlukene. reception wakhe kubangela kwesasa futhi ngaleyo ndlela kubathinta kabi zonke izinhlelo eziyishumi nemitshingo.

Phakathi ukwelashwa, umuthi kumele kubhekwe ukuba kudingekile ukuqapha isimo sokusebenza ka isibindi lesiguli, kanye izinkomba wegazi neuropathy.

Kuyo yonke ukwelashwa isiguli Kwenqatshelwe yini ukuphuza utshwala ngokweqile, njengoba lokhu kungadala hepatotoxicity isenzo izidakamizwa. Kungokufanayo uya caffeine amathuluzi kanye nemikhiqizo.

imithi Okubukwe kunomthelela oqonde ngqo ekhonweni lesiguli kumthamo futhi bahlanganyele kunoma yiluphi neminye imisebenzi ezidinga emakamu eliphezulu ukunakwa.

Izidakamizwa "Kaffetin Cold": nisukele Pharmacy

Ngenxa yokuthi ngokuvamile lokhu imithi isetshenziswa njengophawu izidakamizwa, ikhishwe kuphela kokwethula somuthi nokusetshenziswa kwawo sikadokotela. By the way, ukuthola izidakamizwa ezifana Pharmacy kunzima ngempela. Ngokuvamile ilethwa emva uku-oda.

izidakamizwa ezifanayo

Kukhona izindlela eziningi lapho izidakamizwa okukhulunywa ngalo lapha lingase indawo. Ethandwa kakhulu zihlanganisa lezi ezilandelayo: "Amitsitron Forte", "Antigrippin", "Bol-Ran Premium", "Vokasept", "Gripgo", "Gripkold-N", "Gripotsitron Forte", "Gripflyu", "Dolar", " H Cold "," Koldreks "," Koldfri "," Lemsip Lemon "," Novalgin "" Panadol Ezingeziwe "," Rinzai "," Tamipul "," Farmatsitron "nabanye.