"Dorzopt" (ngeso amaconsi): Umhlahlandlela, ukubuyekezwa, analogs

I-glaucoma - iqembu kunalokho enkulu izifo iso, izimpawu ukwanda ezikhathini ezithile noma unomphela ingcindezi intraocular nge okwalandela ukuthuthukiswa ukukhubazeka, yoma-optic futhi ukwehla acuity ezibukwayo.

Ukuze ekwelapheni izifo usebenzisa izidakamizwa ezahlukene. Imithi obujwayelekile "Dorzopt" (iso amaconsi). Izibuyekezo Umthengi, imiyalelo ukusetshenziswa kwalesi imithi kuzoxoxwa ngezansi.

Ukupakisha kanye nokusungulwa

Yini izidakamizwa iqukethe izidakamizwa "Dorzopt" (iso amaconsi)? Uphiko asebenzayo we umuthi dorzolamide (njengoba hydrochloride). Futhi nomuthi iqukethe izinto ezilandelayo asizayo: Benzalkonium chloride, gietelloza, mannitol, sodium hydroxide, citric acid monohydrate, amanzi ahlanzekile.

umkhiqizo Okubukwe akhiqizwa polyethylene izitsha eziyisikhombisa nge 5 ml weThrojani umlomo wombhobho.

pharmacodynamics

Yiziphi ngeso lehla "Dorzopt"? Umhlahlandlela ibika ukuthi leli thuluzi sendawo carbonic anhydrase inhibitor. It kunomphumela ezicindezelayo phezu intraocular uketshezi uketshezi futhi kuvimbela ukwakheka hydrogen carbonate emanzini buthakathaka ukudluliswa kanye sodium.

Lesi sidakamizwa akakubangeli miosis noma ebusuku ubumpumputhe, kanye spasm yokuhlala.

Pharmacokinetics

ngabe izidakamizwa amuncwa umzimba, "Dorzopt" (iso amaconsi)? Absorption zomuthi senzeka ngokusebenzisa i-cornea kanye ngokusebenzisa esitho futhi sclera. izidakamizwa letindzala ukumuncwa izindleko ziphansi kakhulu.

Uma esegazini, izidakamizwa isithako lingena ngokushesha ku abomvu egazi ne wokuqukethwe lelisetulu anhydrase carbonic 2.

Ukuxhumana-plasma amaprotheni kwenzeka ngo-33%. Umuthi is kuguquka N-dezetilirovanny metabolite, okuyinto akusebenzi kakhulu ngokumelene anhydrase carbonic 2, kodwa uyakwazi ivimbela umuntu anhydrase carbonic.

ukusetshenziswa isikhathi eside zomuthi kuholela ekuqongeleleni yayo erythrocyte.

Kuboniswa imithi ngokusebenzisa nezinso. ukususwa kwawo 2 ukuqedwa isigaba: fast and kancane. Lesi sakamuva kubangelwa ukukhululwa kancane kancane ingxenye esebenzayo kwamangqamuzana egazi abomvu.

isikhathi isigamu-ukuphila izinyanga mayelana 4.

ubufakazi

Lapho prescribers "Dorzopt"? Eye amaconsi kuphumelela kakhulu ekwelapheni isigqugquzeli ingcindezi intraocular e abantu nge nomfutho wegazi ophezulu ocular noma ukufiphala kwamehlo evulekile-pseudoexfoliative (kuhlanganise zesibili).

Izimo

Ngaphansi kwaziphi izimo, awukwazi ukusebenzisa izidakamizwa "Dorzopt"? Eye amaconsi kungukuthi engabelwe kona:

• lactic hyperchloraemic;
• Hypersensitivity izakhi abamelwe;
• ezinzima izinso iziyaluyalu;
• njengoba ingane;
• esikhathini lactation.

Ngokucophelela okukhulu kumele kusetshenziswe leli thuluzi:

• sikashukela;
• iziguli ezine ukungakhuli hepatic;
• labo ukuminyana elincane cornea endothelium amaseli esweni (we awokuthi edema corneal).

nokushintsha kokudla nokufakwa

Nikeza ithuluzi ibhekwa for ekwelapheni izifo iso has kuphela onguchwepheshe ewumngcingo ngemva Ukuhlolisisa nesineke. Bury ekwakhiweni desirably eyodwa consi sac conjunctival ka kathathu ngosuku.

Nge inhlanganisela yemithi beta-blocker izidakamizwa nezokusigcoba ukusebenzisa iconsi kabili ngelanga.

Uma ocular yokwelapha isifo kuhlanganisa ejenti eziningana amehlo, isikhawu phakathi instillation yabo kumele kube imizuzu okungenani eyishumi.

side effects

Uma usebenzisa iso lehla "Dorzopt" Ukusabela wendawo ezilandelayo zingasiza ukuthuthukisa ezigulini:

• ukuzwa ukulunywa nokusha emehlweni, conjunctivitis, paresthesia, edema ijwabu leso, edwengula, blepharitis, ukuzwakala kahle ngombono, photophobia futhi olukha phezulu punctate keratitis.
• Kakhulu akuvamile ngokumelene isicelo zomuthi yilezi: iridocyclitis, okwandisa ukushuba cornea, njengemithi yokungezwani komzimba nokuthile, hypotension iso futhi lamabutho ngwengwzi ngemva antiglaukomatoznyh imisebenzi.

Lefundo side effects:

• umuzwa isicanucanu, ukunambitheka ababayo emlonyeni, ukuthuthukiswa nefrourolitiaza, ukukhathala, migraine, abulalayo exudative erythema multiforme, ezinobuthi epidermal necrolysis, anaemia aplastic, ukuqubuka kwesikhumba futhi agranulocytosis.

amacala ukweqisa izidakamizwa

Yiziphi izimpawu zenzeka lapho usebenzisa i "Dorzopt" ebulilini izidakamizwa? Eyedrops, analogs okuyinto aboniswa ngezansi, anganikela:

• lactic ukuthuthukiswa;
• ukuphazamiseka kwamanzi kanye electrolyte ibhalansi;
• CNS engemihle.

Ukuze ekwelapheni izimo ezinjalo baqashwe symptomatically, ephelezelwa kokulawulwa ezingeni electrolyte negazi pH.

izidakamizwa ekuhlanganyeleni

• Lapho kuhlangene izidakamizwa antiglaucoma ejenti (i-beta-blocker, "dipivefrin", "pilocarpine", "Carbachol") icacisa umphumela wawo.
• Nge "acetazolamide" kwandisa ingozi letindzala engemihle.
• Nge imithamo emikhulu acetylsalicylic acid kwandisa ubuthi zomuthi.

izincomo ezithile

Ukusetshenziswa izitsha eziyisikhombisa multidose kungacupha ukuthuthukiswa keratitis virus. Lokhu kungenxa ukungcoliswa nolwazi lokuqukethwe zabo.

Phakathi ukwelashwa "Dorzoptom" akufanele usebenzise ama-lens benzalkonium chloride kungaba ezinobuthi futhi ngalesi siyingi kubangele ubuhlungu emehlweni.

Analogs futhi intengo izidakamizwa

Buyisela izidakamizwa kubhekwe ukuba iso kungaba ngokusebenzisa izinto ezinjengenkolo "Trusopt" futhi "Floksal". Inani lentengo lomuthi kuyinto ruble mayelana 350.

Izibuyekezo umthengi

Ngeshwa, umthengi Izibuyekezo mayelana izidakamizwa "Dorzopt" awavamile. Phakathi izinzuzo main of leli nothi izidakamizwa ezifana ukutholakala nokuphumelela kwaleso sembatho. Nokho, abanye abathengi bakhathazeka, zendawo letindzala ukusabela ezingezinhle ezenzeka phakathi ukwelashwa nge amathonsi. Kule ndaba, ochwepheshe batusa ukusetshenziswa kwezidakamizwa ngaphansi kwegama "Dorzopt Plus".

Eyedrops eshiwo ngenhla zihlanganisa ezifana izidakamizwa ezengeziwe, ezifana timolol. Isekela amanzi uketshezi intraocular.