"Calcium Nadroparin": imiyalelo, izinkomba, side effects

Ngayiphi ifomu ukuthi likhiqizwa lesi sidakamizwa "Nadroparin Calcium?" Khipha ifomu zomuthi is okwethulwa kulesi sihloko. Futhi, inikeza imininingwane mayelana izici izimali wathi, izinkomba zayo kanye nemiphumela engemihle.

Ifomu, ukwakheka

"Nadroparin Calcium" - isixazululo senzelwe abaphathi ngaphansi kwesikhumba. ukulungiselela Okubukwe kuyinto esobala, ukukhanya yellow noma kungekho nto enemibala emihle, kancane opalescent umthamo liquid. isithako wayo esebenzayo igama elifanayo ketshezi - calcium nadroparin. Futhi isakhiwo zomuthi zihlanganisa izithako elandelayo eyengeziwe: amanzi d / futhi isixazululo nge-calcium hydroxide noma hydrochloric acid (alulaze).

Ngo ukuthengiswa "Nadroparin Calcium" iza olulodwa umthamo imijovo tihlelwe e amabhamuza kanye amaphakethe of ephepheni.

izakhiwo zomuthi

"Nadroparin Calcium" limelela antithrombotic futhi anticoagulant ejenti. Ngokusho imiyalelo, lokhu umuthi ophansi yamangqamuzana isisindo heparin, okuyinto lalikhishwa heparin ejwayelekile, by depolymerisation. It has ziyezwana ephezulu amaprotheni igazi antithrombin 3 futhi isici kahle kuvimbela Xa.

Asinakusho ukuthi izidakamizwa okukhulunywa lishintsha nemingcele rheological kwegazi, okungukuthi, kunciphisa viscosity yayo, kwandisa permeability kwamaseli ulwelwesi-granulocyte nama-platelet, iphinde ivimbele ukuthuthukiswa inqubo sokugembula, njengoba ukuvaleka imithambo yegazi.

Uma eqhathaniswa heparin unfractionated, wathi isixazululo kunomphumela buthaka kumsebenzi platelet futhi aggregation hemostasis eyinhloko.

Kinetics kwezimali

Kuyini ikhono kinetic ukuba lesi sidakamizwa "Nadroparin Calcium?" Ngemva kokuphathwa ongama, anti-Xa umsebenzi oyinhloko walo ejenti siyenzeka ngemuva kwamahora 5. Ngaphezu kwalokho, ingxenye-ukuphila salo 2 amahora. Lesi sidakamizwa is akheka esibindini ngu depolymerization futhi desulfation.

enquma

ukuminyana emithambo yegazi kungenzeka ngenxa yezizathu ezihlukahlukene. Ukuvimbela ukuthuthukiswa inqubo sokugembula futhi ngempela esiyingozi kanjalo, odokotela abaningi linqume ukuba iziguli zabo izidakamizwa "Fraksiparin", uphiko asebenzayo zazo calcium nadroparin. Ngakho, wathi izindlela kuboniswa ukusetshenziswa:

• ekwelapheni thromboembolism;
• nokuvimbela izenzakalo thromboembolic (isibonelo, phakathi ukungenelela wamathambo futhi kuhlinzwa kubantu zisengozini enkulu yokuba lesi izenzakalo thrombotic, kuhlanganise ukwehluleka (acute) inhliziyo noma zokuphefumula);

• ekwelapheni isilethikusebenza futhi angina engazinzile;
• nokuvimbela igazi ekunqandeni

Uvala ukuqokwa

embolism - into kunalokho yingozi. Nokho, ngisho kule wombuso, lesi sidakamizwa "Fraksiparin" akuyona njalo eyabelwe iziguli. Ochwepheshe bezifo, lo muthi unamandla Izimo ezilandelayo:

• ukopha intracranial;
• thrombocytopenia uma usebenzisa nadroparin;
• izilonda organic yezitho zangaphakathi nge ukuthambekela ukopha;
• izimpawu noma ingozi eliphezulu ukopha, okuyinto lihlotshaniswa iziyaluyalu hemostasis;
• ukuhlinzwa nobuchopho, umgogodla cord yokulimala, kanye izitho ezibukwayo;
• acute endocarditis webhaktheriya;
• yobudala ezincane;
• ukungakhuli ezinzima kwezinso;
• sensitivity high ukuze nadroparin.

isicelo ngokucophelela

Be uqaphele "Fraksiparin" isidakamizwa ezinqunyiwe kuphela ezimweni ezihilela ingozi eliphezulu ukopha, kuhlanganise:

• ukwehluleka kwezinso;
• wegazi vele ophakeme kakhulu;
• nasezinkingeni ezilandela ngemva kokuhlinzwa;
• yokwehluleka kwesibindi ukusebenza;
• abantu enesisindo esingaphansi 40 kg;
• izilonda peptic;
• iziyaluyalu kwegazi e-retina noma choroid;
• lihambisana izidakamizwa ukuthi kwandisa ingozi yokungenwa ukopha.

Izidakamizwa "Nadroparin Calcium": yokusetshenziswa

Ngokusho imiyalelo izimali kumele phansi kwesikhumba yaphathwa esifundeni besisu (ujike kuze kufike ohlangothini lwesobunxele futhi kwesokudla). Kulokhu, isiguli kufanele babe sesimweni lisalele. Futhi akuvumelekile ukwenza umjovo ethangeni.

I umthamo we-ejenti kukhethwa udokotela kuye ebufakazini obutholakalayo. Ngokwesibonelo, ukuze kuvikelwe thromboembolism practice kuhlinzwa usebenzisa umthamo "Fraksiparina", ilingana 0.3 ml. Uma lokhu kulungiselelwa saphathwa 4 amahora ngaphambi ukusebenza kuhlelwe, futhi kamuva - uma nsuku zonke.

Ubude yokwelashwa nale ejenti futhi kuncike isifo ekhona (ngokuvamisile izinsuku 6).

side effects

Isicelo obuyekezwayo, izidakamizwa kungabangela eziningi nemiphumela engemihle, ikakhulukazi:

• ukopha kwasendaweni ezahlukene;
• ukwanda enzyme isibindi;
• thrombocytopenia, futhi eosinophilia;
• hypersensitivity ukusabela;
• ukusabela zendawo ezifana ukubonakala hematoma ongama endaweni umjovo, ukwakheka izigaxa kanzima, zinyamalale ngemva kwezinsuku ezimbalwa, necrosis kwesikhumba endaweni yokuphathwa;
• hyperkalemia, futhi priapism.

Izibuyekezo

ukuminyana emithambo yegazi angase simo singenzeka kunoma yimuphi umuntu. Ngakho-ke, abantu kwegazi kahle kakhulu ngokuvamile ezinqunyiwe isidakamizwa "Fraksiparin" noma okuthiwa "Nadroparin calcium." Iziguli zithi kusho kahle ubhekana abangababi bemisebenzi yaso ngqo. Nokho, kufanele kuphawulwe ukuthi lokhu izidakamizwa kubangela ukuthuthukiswa ukusabela ezingezinhle. Kulokhu, ochwepheshe batusa ukuba esikhundleni saso alethe izidakamizwa ephephile.