Umuthi 'Ondansetron ": analogue, yokusetshenziswa, intengo

Kukhona pathologies eziningi ezidinga ethola antiemetics, okuvumela ukususa nesicanucanu izimpawu ubuthi. Lokhu kubalulekile ikakhulukazi esikhathini postoperative, lapho umzimba ihamba kusukela izinzwa. Udinga ukuba ezinqunyiwe izidakamizwa ngesikhathi ngelashwa nangemithi futhi ukwelashwa ngemisebe. Lezi zihlanganisa izindlela eziphumelelayo ukwelapha "Ondansetron". Analogs ( "Emetron" izidakamizwa "Latran" "Zofran") futhi ngesikhathi esifushane kuzosusa izimpawu zokudakwa nokuhlanza.

nemithi Isenzo "Ondansetron"

Imithi kungokwalabo iqembu antiemetics. Ngokunenzuzo futhi ngesikhathi esifushane, lokhu kuwukhulula isicanucanu nokuhlanza, okwenzeka esikhathini postoperative emva nokwelashwa ngamakhemikhali kanye radiotherapy. Effect zomuthi ukuthi angamuvimba ngokukhetha serotonin 5-HT3 receptor. Ngenxa ukusilela we reflex Gag.

Ngemva kokungenisa ejenti ngokushesha ugxile esiswini. Cishe ngo-100% elihlobene ne Amaprotheni egazi. Isibindi uchayeke umzimba okusezingeni eliphezulu. Phakathi namahora angu-amane zomuthi ifinyelela umphumela wawo maximal zokwelapha. Sihamba isicanucanu nokuhlanza ngenxa nomuthi "Ondansetron". Analogs futhi esikhundleni mithi izakhiwo ezifanayo futhi Ungashintshanisa ngokugcwele yasekuqaleni.

Izinkomba kanye contraindications

The main izinkomba - ukwelashwa kanye nokuvinjelwa isicanucanu nokuhlanza emva nokwelashwa ngamakhemikhali kanye radiotherapy, kanye esikhathini postoperative. Kukhona ezinye Izimo:

• Awukwazi ukuthatha imithi engxenyeni yokuqala ka nokukhulelwa;
• hypersensitivity kuya izingxenye;
• iqondiswa ngokuqapha iziguli isifo sezinso futhi isibindi.

isicelo

Umuthi unikezwa umuntu ngamunye. Izinga Daily incike kobukhulu izimpawu, futhi ukudakwa by odlula ngemisebe nangamakhemikhali. Esikhathini esiyiminyaka emva imithi ukusebenza babelwe izikhathi eziningana ngosuku kuze ukunyamalala ngokuphelele izimpawu isicanucanu nokuhlanza. Kuphela udokotela angaba linqume esebenzisa "Ondansetron» (Ondansetron). Imiyalo umuthi ngaphakathi emaphaketheni ekhemisi.

Akunconyelwe co-ukuphatha nge inducers ka cytochrome uhlelo enzymatic, okungase kuholele ekubeni uthunyelelwe ukwehla ngo imvume kanye nokubekezelela ketshezi main (ondansetron).

Kuyinto engenakwenzeka linqume izidakamizwa e senyanga yokuqala sokukhulelwa. Uma udinga ukusebenzisa izidakamizwa ngesikhathi lactation, kubalulekile ukuba bangayeki yokudla. Futhi iziguli ngemva kokuhlinzwa besisu kudingeke uthathe isidakamizwa ngokuqapha ukuze ufihle izimpawu acute isimiso emathunjini. Njengoba isifo sesibindi ayikwazi ukudlula mg 8 umthamo nomuthi "Ondansetron".

Analogs futhi intengo izinkomba kanye contraindications - konke lokhu kwaziswa kuyadingeka ukuze ucacise ngaphambi kokwelashwa.

Intengo zomuthi - cishe u- $ 100 ucezu ngalunye.

Imiphumela engemihle:

• ukuphathwa ikhanda;
• eza angaboni kahle nesiyezi;
• ingcindezi ukuncishiswa;
• tachycardia;
• komzimba;
• komzimba ekhanda lami.

"Latran"

Libhekisela antiemetics. Ngokuphumelelayo aqede izimpawu of isicanucanu nokuhlanza esikhathini postoperative, ngokuhamba ngamakhemikhali futhi welashwa ngemisebe. Umuthi uyakwazi ekuvimbeni abakhethayo serotonin 5-HT3 receptor. Uma kugwinywe, imithi isikhathi esifushane ugxile esiswini. Cishe ngo-100% elihlobene ne Amaprotheni egazi. Dlula umzimba kwesibindi ngo hydroxylation.

ukutholakala Maximum zomuthi ibangelwa amahora amane ukuthatha komthamo wokuqala. Lezo ine phezu imithi emzimbeni "Latran". It has a efanayo impahla ejenti "Ondansetron". Analogue, bomcondvofana kanye imithi ejwayelekile ingasetshenziswa kuphela emva kokubonisana udokotela wakho.

Izindleko imithi ruble 180-200 Pharmacy ezahlukene.

Izici isicelo

Nokwelashwa kwezinkinga isicanucanu nokuhlanza esikhathini postoperative, futhi ngemva nokwelashwa ngamakhemikhali futhi welashwa ngemisebe. Awukwazi ukuzinikeza ejenti e senyanga yokuqala sokukhulelwa futhi uma hypersensitivity kuya izidakamizwa. Futhi, akukho izindlela ezinqunyiwe ku zokugula we isibindi kanye nezinso. Umuthi ayikwazi lisetshenziswe ukudla okunobuthi noma utshwala.

Umthamo Kumiswa umuntu ngamunye futhi kucatshangelwa ngobucayi isifo. Inkambo incike izimpawu kanye nokuba khona ukudakwa umzimba. Omunye awukwazi ukuthatha ngokuhlanganyela amathebhulethi, inhibitor ka cytochrome isozyme. Ngaphandle kokuxhumana udokotela is hhayi Kunconywa ukuthatha izidakamizwa "Latran", kanye nedivaysi yezokwelapha "Ondansetron" (Isixazululo for umjovo). Iziqondiso ukuchaza indlela yokusebenzisa imithi kuphela ngesizathu sokuthola ulwazi.

side effects

Ezimweni eziningi, umuthi asibekezeleleki kahle. Izimpawu ezilandelayo kungenzeka kakhulu kuyaqabukela:

• angaboni kahle nesiyezi, ukuze izivakashi;
• ikhanda;
• bradycardia;
• iconsi okuphawulekayo ingcindezi;
• ukuqunjelwa;
• Ubuhlungu obukhulu besisu,
• ukushisa isasasa.

Awukwazi ukuzinikeza isixazululo noma ithebhulethi ngesikhathi sokukhulelwa kanye lactation. Futhi, ngokuqapha kufanele libekwe emva kokuhlinzwa phezu peritoneum, ngakho miss izimpawu acute isimiso emathunjini. Lezi zinyathelo kumele ebonwe ekwelapheni izidakamizwa "Ondansetron". Yokusetshenziswa, analogs, umthamo efanele - konke ukwaziswa kufanele ifundwe ngaphambi kokwelashwa, futhi uma unemibuzo ubheke onguchwepheshe for izeluleko.

"Zofran"

Agent libhekisela eqenjini antiemetics. Ngokuphumelelayo aqede izimpawu of isicanucanu nokuhlanza ngesikhathi nokwelashwa ngamakhemikhali, futhi ukwelashwa ngemisebe ngemva kokuhlinzwa. Kusho bangazalanisa ukuvimba serotonin 5-HT3 receptor, okuyinto kunciphisa uphawu ubuthi. Cishe ngo-100% exhunywe kwi-Amaprotheni egazi. bioavailability Maximum waphawula ngemva 4 amahora emva ukuthatha imithi. Ngo "Zofran" it is ikakhulukazi akheka esibindini ketshezi eyinhloko zezempilo. Oku kufanele wafunda njengoba ngaphambi kokusebenzisa izidakamizwa "Ondansetron" imfundiso. Analogs ngokuvamile musa ihluke ukubunjwa nokubonakaliswa. Ingabe "Zofran" ruble mayelana 300.

ukusetshenziswa Izici

Eyabelwe ngokwelashwa nokuvimbela esikhathini emva kokuhlinzwa, ngelashwa nangemithi futhi ukwelashwa ngemisebe. Akumele ezithathwe engxenyeni yokuqala ka sokukhulelwa futhi ngesikhathi uncelisa. Liphinde hhayi Kunconywa uma hypersensitivity kuya izidakamizwa. I nomuthi ingasetshenziswa ukuyeka ukuhlanza kanye zokuqaleka izimpawu phakathi ukudakwa ubuthi.

Dose usungula udokotela kuphela, futhi kuncike ngobucayi nesineke emva nokwelashwa ngamakhemikhali ukwelashwa nangemuva ukuhlinzwa. Umuthi esithathwayo ukuqedela ukunyamalala izimpawu zokudakwa. Akunconyelwe co-ukuphatha nge inhibitor ka isoenzyme isochrome uhlelo. Lokhu kufanele kubhekwe ekwelapheni izidakamizwa "Ondansetron". Izidakamizwa analogue ngokugcwele uyakwazi esikhundleni sokuqala bese ugcine esigulini phakathi ukuhlanza nesicanucanu.

Imiphumela engemihle:

• eza isiyezi kanye angaboni kahle;
• ikhanda;
• ukuqunjelwa noma isifo sohudo;
• ukwehlisa umfutho wegazi;
• bradycardia;
• ubuhlungu esiswini.

Ngezinye okuvela iyiphi izimpawu untoward kufanele afune usizo lodokotela. Uchwepheshe ukunciphisa umthamo noma anikele esikhundleni izinga.

"Emetron"

izidakamizwa Antiemetic ukuthi ukuvimba ama-receptor serotonin futhi kunomphumela emaphakathi.

Umuthi senziwa ngesimo isixazululo ophuzi kanye amaphilisi. Izimali nakhelwe nokuqedwa ukuhlanza nesicanucanu emva kokuhlinzwa futhi ngesikhathi ngelashwa nangemithi nemisebe yokwelapha. Ukuze abaphathi esicutshini noma emthanjeni, waphawula umkhuba nokuncipha ubuthi angu-10. Umphumela ofanayo has "Ondansetron" isixazululo nokulungiselela. Analogue azifane kakhulu kwengoma.

Intengo zomuthi kwezinye Pharmacy idlule ruble 1,200 iphakethe ngalinye.

Izinkomba kanye contraindications

Inikezwa ukuqeda isicanucanu nokuhlanza phakathi nokuhlinzwa kanye ngesikhathi ngelashwa nangemithi nemisebe yokwelapha ezinganeni nakubantu abadala. Ukuqeda izidakamizwa ukudakwa uma ubuthi ayikwazi ukusetshenziswa. Kukhona Izimo eziningana ukuze:

• ngesikhathi sokukhulelwa;
• lactation;
• kuze kube iminyaka engu-2;
• hypersensitivity kuya ingxenye esebenzayo.

Umuthi iqondiswa at umthamo mg ngelanga 8 kuya kwezingu-32. Izinga Daily incike kobukhulu ukudakwa kanye izici ngamunye umzimba. Okumele kuqashelwe babelwe iziguli ikhambi ne zokugula we isibindi kanye nezinso. Futhi kusho "Emetron" ngemithamo ongaphakeme esetshenziswa kwasebekhulile.

Izibuyekezo

Ezimweni eziningi, le izidakamizwa has a okubuyayo is kahle ikubekezelele iziguli. Ngesikhashana nje it ususa izimpawu zokudakwa, okuholela ukuhlanza nesicanucanu. Umuthi akulimazi emzimbeni futhi ingasatshenziswa kuze kube ukunyamalala ephelele izimpawu ubuthi. Ngokusho izimpendulo iziguli nodokotela ingaqala ukusabela iguliswa lesi sidakamizwa "Ondansetron". Analogue kwezimali kungaba kuvuse isifuba ngisho ukushaqeka anaphylactic. Ngakho-ke Isikali amasethi kuphela uchwepheshe ikhumbula izici ngamunye isiguli.

Umuthi ayiluthi bese kukhishelwa ngesimo amaphilisi kanye isixazululo, okuyinto efanelekayo yisiphi isiguli nge inqubo zaba namandla kakhulu. ukwakhiwa okunjalo ingasetshenziswa ne eminyakeni emibili ubudala. Thenga imithi ngasiphi ekhemisi. Odokotela abaningi batusa umuthi ukuze akhulule izimpawu zokudakwa.

Uma kukhona isidingo sokukhetha ukuqoka ithuluzi phakathi ibele, kungcono ukuba ayiyeke le lactation. Ochwepheshe uqaphele ukuthi isithako singena ubisi kungalimaza impilo umntwana osanda kuzalwa. Futhi-ke, njengoba ngaphambi kokuthatha izidakamizwa kudinga kokubonisana lwangaphambili udokotela - ke ingozi nemiphumela engathandeki yalawo maphilisi ngeke kuncishiswe.