"Tsinarin": yokusetshenziswa, nozakwabo yangempela

blocker calcium channel ngokuthi iqembu heterogeneous izidakamizwa ukuthi ezifanayo yokusebenza isimiso, kodwa kuhluke kwezinye izakhiwo, kuhlanganise nemingcele kinetic, izicubu selectivity nomthelela kwenhliziyo.

Isimiso esiyisisekelo wokusebenza imithi enjalo ukuthi bayakwazi zivimbela Ukungena Ca ion isuke endaweni extracellular ku imithambo yegazi kanye senhliziyo esilimele amaseli nge iziteshi calcium (ukubambezela). Lokhu kuholela evelele vasodilator senzo.

Ethandwa kakhulu calcium omelene buyisidakamizwa "tsinarin". Yokusetshenziswa, intengo, kanye nokubuyekeza indlela yokwakheka mali zizokhishwa kuchaziwe ngezansi.

ifomu ukukhululwa, emabhokisini incazelo, ukwakheka

Izidakamizwa "tsinarin", ukubuyekezwa zazo akhayo, it is ithunyelwa ngesimo biconvex, round and amaphilisi emhlophe. ingxenye ngokuyinhloko cinnarizine. Ngaphandle-ke, ukudala izidakamizwa yakhiwa njengoba excipients povidone K25, i-lactose, ukolo isitashi, colloidal Silicon dioxide futhi magnesium stearate.

Lokhu kusho ukuthi ungakwazi ukuthenga kumaseli nentaba.

izici umkhiqizo

on isicelo "tsinarin" izidakamizwa Guide ibika ukuthi omelene abakhethayo iziteshi calcium (ukubambezela). Kunciphisa ukugeleza Ca ion ku amaseli bese kunciphisa inani plasmolemma edepho, kodwa futhi sithuthukisa vasodilating umphumela carbon dioxide futhi kunciphisa imisipha ithoni arteriole.

Ngokwenza ngqo ezitsheni, umuthi iyehlisa abasabela ngayo umsoco (norepinephrine, epinephrine, angiotensin, vasopressin, futhi Dopamine). Phawula futhi ukuthi nomuthi kubhekwe uye vasodilating izakhiwo, kuhlanganise ngokumelene izitsha palsy. Kulokhu, it akunamthelela blood pressure.

Izidakamizwa "tsinarin", intengo zazo laloku lokubhalwe lapha ngentasi, is ngokulinganisela liphinyiselwe umsebenzi antihistamine, kunciphisa excitability we-apharathasi vestibular futhi kunciphisa ithoni NS nozwela. Lesi sidakamizwa ngempumelelo liziphatha sengathi kokuqala esingamahlalakhona cerebrovascular futhi ezingalapheki. Abantu ne kahle kwegazi neuropathy ngcono igazi ligeleze zonke izicubu kanye izitho. Kuba yisikhathi futhi lapho esebenzisa ukunciphisa viscosity igazi, kwandisa kuyaqina we ulwelwesi of abomvu egazi ashaye kanye muscle ukumelana hypoxia.

I kinetics zomuthi

Iziphi izici kinetic esivela izidakamizwa "tsinarin"? Iziyalezo yokusetshenziswa uthi lokhu inxusa resorbed emathunjini nasesiswini. Ubuningi isiqongo plasma izuzwe ngemuva kwamahora amathathu. Ukuxhumana cinnarizine plasma amaprotheni kuyinto 91%. Umuthi is akheka esibindini ngokuphelele. isikhathi sayo isigamu-ukuphila amahora amane. It kuvela imithi umchamo kanye endleni.

ubufakazi

Izidakamizwa "tsinarin" siboniswa reception:

• komqondo senile;
• unhlangothi ischemic;
• ezibuhlungu cranial;
• izimo post-unhlangothi (kufaka phakathi oluhambisana unhlangothi);
• semithambo encephalopathy;
• ngokuba kinetoses prophylaxis (zasolwandle noma isifo emoyeni, kanye ngesikhathi unyakazisa);
• iziyaluyalu vestibular (kuhlanganise ne nesifo i-Meniere sika, tinnitus, inzululwane, nystagmus, ukuhlanza nesicanucanu umsuka labyrinthine);
• migraine (nokuvinjelwa ukuhlaselwa);
• kokunikezwa kwe-kwegazi neuropathy.

Izimo ukuba ngamukele izibhebhe

Kungaphansi kwaziphi izimo akufanele ezinqunyiwe isidakamizwa "tsinarin"? Iziyalezo imibiko ukusetshenziswa ukuthi lokhu remedy is contraindicated ku:

• hypersensitivity;
• sokukhulelwa;
• ibele.

Kufanele kuqashelwe ukuthi le izidakamizwa ezinqunyiwe ngokuqapha e Parkinson.

Izidakamizwa "tsinarin": yokusetshenziswa

amaphilisi kufanele ibhekwe ngaphakathi, okungcono emva kokudla.

Lapho ephazamisekile, ubuchopho kwegazi imithi iphathwe imali 25-50 mg kathathu ngosuku, futhi neuropathy kwegazi - at 50-75 mg ne kaningi efanayo.

Lapho iziyaluyalu vestibular Kunconywa ukuthatha izidakamizwa ngesikhathi 25 mg kathathu ngosuku. Lapho kinetosis noma okuthiwa "umgwaqo" iziguli omdala isifo iqondiswa 25 mg izidakamizwa imizuzu 30 ngaphambi uhambo. Uma kudingeka, imithi ethola okuphindaphindiwe ngemuva kwamahora 6 (e esilinganayo).

Ezinganeni, lokhu izidakamizwa ebekiwe inani 1/2 umthamo omdala.

Ngezinye sensitivity high yokwelapha nomuthi iqala isigamu umthamo ukwandisa kancane kancane. Inkambo yokwelashwa zingase zithathe isikhathi esisukela amasonto 2-3 kuya ezinyangeni eziningana.

side effects

Lesi sidakamizwa kungadala lokhu okulandelayo ukusabela uhlangothi:

• nomlomo owomile, dyspepsia, ubuhlungu epigastric, jaundice cholestatic;
• ukozela, ubuhlungu bekhanda, ukukhathala, kanye disorder extrapyramidal (isibonelo, ukwanda imisipha ithoni, eliqhaqhazelayo kwamalungu omzimba, ngisho hypokinesia);
• ulele planus, ukujuluka, lupus-like syndrome, ukuqubuka kwesikhumba;
• imiphumela iguliswa, isisindo somzimba, kunciphisa umfutho wegazi.

Inani, iholide analogue izidakamizwa kanye nokubuyekeza ngakho

Ukudlulisela kwemithi bohlanga ka-calcium channel blocker, eyenziwa udokotela. Inani lentengo lomuthi kuyinto ruble mayelana 20-50.

Uma kudingeka, ithuluzi ungayithola enye izidakamizwa "Vertizin", "Diziron", "Stugezin", "stugeron", "Tsinazin", "Tsinedil" "Cinnarizine" kanjalonjalo.

abathengi abaningi bathatha lokhu omelene, bethi siwumsebenzi esebenza kahle kakhulu futhi ngempumelelo izidakamizwa. Amaphilisi "tsinarin" kusiza kuqedwe izifo ezibangelwa vestibular neziyaluyalu enqubeni kwegazi. Ngaphezu kwalokho, lokhu izidakamizwa kuye kwaba nomphumela omuhle emzimbeni womuntu migraines, komqondo senile nemibandela post-stroke.

Kufanele futhi wazi ukuthi i-ejenti kubhekwe ngokuvamile kubangela ohlangothini ukusabela. Ukuze uvimbele ukuthuthukiswa yabo, kufanele ngokuqinile ukuhambisana nayo yonke izincomo udokotela. Thatha iphilisi "tsinarin" kwalo yedwa, kuyovinjwa. Kufanele inqunywe kuphela udokotela ukuba khona.