Tablets kusuka ukubhema "varenicline": ukubuyekezwa kanye yokusetshenziswa

Inkinga ukuyeka ugwayi Sekuyisikhathi eside njengelinye lamazwe kunazo ukuphokophela. Lutho ishintshile manje. Isibalo ababhemayo luyanda njalo ngonyaka. abalandeli abaningi umkhuba-nicotine imisiwe usikilidi ukuthenga esemncane kakhulu. Ngo intsha, isenzo esinjalo lihlotshaniswa imiqondo yokuba umuntu omdala. Kodwa isikhathi siqhubeka, umzimba Ufika esetshenziswa, kwakhiwa sincike-nicotine it is. Bese kuthi-ke inkinga iqala nge wezempilo: grey ukubonakala, a isifuba esomile, imibimbi kwesikhathi ngo abesifazane. Ngeshwa, umonakalo kagwayi emzimbeni yethu siqale ukuqaphela sekwephuzile. Akuwona wonke umuntu uphendukela zinike. Ezimweni ezinjalo, ungase iphendukele izidakamizwa. Ngokwesibonelo, khetha iphilisi smoking "varenicline". Namuhla, zingabantu ethandwa. Basuke Kunconywa odokotela, osaziwayo, abantu abavamile. Kungani? Than okubafanele ukuhlonishwa okunjalo? Ake sizame ukuhlunga lokhu ndawonye.

Yini izibalo

Permanent izifundo zesayensi yokuhlalisana kwabantu futhi ucwaningo lubonisa iqiniso eliduduzayo kakhulu. Emhlabeni wonke, inani besilisa ababhemayo 50%. A abesifazane ukubhema zokhahlamba kusuka 10% kuya ku 50%. Lokho a lot. Cishe isigamu sabantu abasemhlabeni sika kuheleza nicotine. Ngakho-ke, namuhla amaphilisi afanele ngokumelene "varenicline" ukubhema. Ngempela, cishe u-70% abantu ababhemayo, ngoba siqaphela umonakalo nicotine, abafuna ukuyeka ukubhema. Kodwa kuvela akusiwona wonke, kodwa% 5 kuphela. Futhi akusiyo ngisho amandla intando, yize-ke, futhi, ingafeza indima enkulu emizamweni yakho ukuqala indlela yokuphila enempilo. Kodwa kubalulekile ukuba acabangele esinye isici. I-nicotine akukanciphi umlutha kunemithi. Ngokwesibonelo, i-cocaine noma i-heroin. Futhi indoda ayivelanga njalo siyabekezeleleka bebodwa, ngoba kukhona ushintsho eqinile emzimbeni. Futhi lapha basisize "varenicline" amaphilisi kusuka ukubhema. Ingabe ziyabasiza? Izibuyekezo isiphakamiso ekufezeni umphumela oyifunayo. Kodwa lokho ebangela ukuphumelela izidakamizwa?

A amazwi ambalwa ku-nicotine

Ukuze siphendule lo mbuzo, kufanele nje ukuqonda izenzo kanjani i-nicotine. Bese ungakhetha indlela yokubhekana nayo. Ngokwesibonelo, amaphilisi e-nicotine ukuluthwa "varenicline".

Into wukuthi engene umzimba wethu, i-nicotine enza receptor ethize ebuchosheni. Ngakho-ke, ngaphakathi imizuzwana embalwa ngemva indoda abakhukhumele usikilidi, uqala ukuzizwa umuzwa ojabulisayo. Ukuthi yizinto ezihlobene ukukhululwa emgudwini wegazi ka-hormone ekhethekile. Odokotela ukuyibiza Dopamine, noma "ama-hormone injabulo". Kodwa ngokuhamba kwesikhathi lokuhlushwa yayo incipha, futhi futhi obhemayo eseqala ukuzwa ukungakhululeki. Kukhona isidingo usikilidi entsha, ukuthola ingxenye fun.

Umlando "varenicline"

Njengoba ubona, kukhona umjikelezo omubi. It kuholela yokuthi 3 million abantu abafa unyaka ngamunye ngenxa yokubhema. angeke Lezi zinombolo batshele. Sekuyisikhathi eside ososayensi wahlushwa yokusesha izindlela ngisindise izwe kusukela isifo i-nicotine. Futhi ekuqaleni kwekhulu lama-21, ikhambi utholakale. "Varenicline" Kwakukhona amaphilisi kusuka ukubhema. Isikweletu esingu ngoba icebo yabo kungokwalabo Centre of Neurobiology ngokuthi Pfizer. Kuyinto umsebenzi lesikhungo - nomkami Co - waphayona futhi wasungula iphilisi akusize ukuba uyeke ukubhema.

kanjani "varenicline" ithebhulethi?

Ngakho kwakunabantu abangu-amaphilisi "varenicline" ukubhema. Ingabe ziyabasiza? Kuyini icebo izenzo zabo? Ake ubuyele emuva ukuziphatha nicotine. It kuvela ukuthi umphumela wawo receptor ingavinjwa. Indlela ukukwenza? elula kakhulu. indawo nicotine udinga ukuthatha enye into. Wabe ngeke bakwazi ukwenza imisebenzi yaso kanye kunomphumela Ugqozi. Ungahlali endaweni eyodwa, i-nicotine nentuthu eningi ushiya umzimba bese uphinde akakubangeli kuye phi hlungu.

Kungenxa isikimu okunjalo futhi izenzo izindlela newfangled ka Pfizer inkampani. Kuthinta la mangqamuzana ubuchopho, kanjalo esikhundleni nicotine. Ngenxa yalokho, umthelela izinto eziyingozi ivinjelwe. Futhi, umuntu usathola kutitfokotisa ugwayi. Ngenxa yalesi, bamfuna izibhebhe ezazisezandleni Ukubhema "varenicline". Impendulo kulezo abantu kakade luwathathe, zibonisa ukuthi phakathi Puff, abagcinanga neze imizwelo eyakhayo, kodwa, ngokuphambene nalokho, uhlangabezana ukunambitheka edabukisayo. Ngakho, unxanela nabo babengicindezela ukuba ngibheme kuyehla kakhulu. Kuncipha iba namandla isifiso imisiwe usikilidi.

Kodwa "varenicline" iphilisi ifa kwesinye isakhiwo ewusizo. Bayakwazi ukunciphisa izimpawu ukuthi zenzeka lapho uyeka ukubhema. Lokho, umuntu ehlupheka ezincane emzimbeni.

Yini odokotela bethi?

Ngaphambi kokuqala imishanguzo umkhiqizo ezintsha, okuhle ukulalela ochwepheshe. Odokotela bakwazisa ngempela le-Tablets kusuka ukubhema "varenicline". Uphenyo odokotela bathi leli thuluzi kuyasiza ngempela baphumelele ekulweni-nicotine. Abantu abaningi babebhekwa njengabangakufanelekeli kagwayi, Nihlukanisiwe kulo mkhuba ngaphandle kobunzima.

Ukuqinisekiswa amazwi abo ukhonza njengoba izibalo zomhlaba wonke. Izidakamizwa ngemva zokwelapha waqhubeka ukudayiswa ngo-2006. It ngenkuthalo baqala ukulamukela ababhemayo emazweni ahlukahlukene. Kuwo lo nyaka, izibhebhe ezazisezandleni Ukubhema "varenicline" esetshenziswa abantu 9000. Futhi 2007 lwaluwushintsho inkampani Pfizer. Umuthi, ithuthukiswe Dzhotamom Co., iwine uGalen. Emkhakheni wezokwelapha ke okulingana uMklomelo KaNobel.

Nokho, naphezu kwalokhu ukuqashelwa international, bonke odokotela bathi mayelana imiphumela engemihle kungenzeka uma ethola izimali. Sanquma ukukhetha amaphilisi kusuka ukubhema "varenicline"? Imiyalelo uzokutshela mayelana zonke izakhiwo zalo. Awu futhi uvakashele udokotela wakho ukuba uthintane naye. Ukuvakashela udokotela owazi ngempilo yakho yonke ukusiza ukugwema lezimanga ezingemnandi ngesikhatsi ukwelashwa.

Sizobe ukukhuluma okuningi mayelana "varenicline"

Ngakho, usuthathe isinqumo ukuyeka ukubhema? "Varenicline" amaphilisi ingakusiza nale. Phela, ziqukethe varenicline. Le into okuthiwa omelene-nicotine. Varenicline uyakwazi zishukumisa receptor nicotinic. Kodwa, ngokungafani kakhulu nicotine, umthelela wabo omncane. Uyakwazi ukuthonya indlela obhekene kumiswa umuzwa kutitfokotisa usikilidi ngabhema. Varenicline umane amabhlogo ke. Ngenxa yalokho, umuntu obhemayo engazizwa yimuphi umphumela kokuqina, kanye nesidingo kubhema ke kancane kancane kunciphisa. Ngaphezu kwalokho, varenicline uyakwazi ekudambiseni izimpawu zokuqaleka okubonakala ngokushesha uma kwenzeka ukwehluleka ugwayi.

izimfihlo varenicline

Njengoba kusithinta varenicline, aqukethe "varenicline" ithebhulethi? Umhlahlandlela ukunika ulwazi lemininingwane mayelana nokuthi lolu daba.

• Varenicline is kahle angena igazi, iqinisekisa ekulenzeni libe namandla. Ubuningi esiphezulu kufinyelelwa 3-4 amahora ngemva sokuphuzisa.
• Ingqikithi ayilethwa nje yilokho ebuchosheni. It is nombala basakaza emzimbeni.
• Kuyaphawuleka ukuthi varenicline cishe akashintshi isimo sawo futhi Asingeni iyiphi ukusabela emzimbeni. 92% wabantu isidakamizwa excreted zinjalo. Futhi kuphela asele 8% bashiya imizimba yethu ngesimo metabolites.
• Excretion izinto zenziwa cishe 24 amahora. Lokho, ngemuva kosuku umzimba wakho ngeke wathola khona varenicline.
• Ngaphezu kwalokho, lo mkhiqizo kungasetshenziswa kanye neminye imithi. izifundo zokwelapha luye lwabonisa ukuthi varenicline akanayo izinkomba ongathandeki ekuxhumaneni nezinye izidakamizwa.
• Kodwa ukuthatha izidakamizwa on isizinda lokudakwa utshwala kungaholela yezinkinga neuropsychiatric. Amajaqamba - wemiphumela elula kuzo lezo zimo.
• Kubi uthola varenicline kanye nezinye anti-ukubhema. Ngokwesibonelo, ne "Nicorette" efanayo. Ezimweni ezinjalo, kungandisa amathuba okuba nemiphumela engemihle.

Izimo

Abaningi ababhemayo babone ukukhanya ekupheleni emhubheni ngemva ayesebenzisa ithebhulethi smoking "varenicline". Izibuyekezo ubufakazi ukusebenza kwabo. Kodwa musa ukusheshe ekhemisi eseduze ukuthenga amaphakheji eziningana. Kungenzeka lusizo kakhulu kuwe. Iqiniso lokuthi ithuluzi has Izimo yayo.

1. Kungcono ukulahla ukusetshenziswa kwezidakamizwa phakathi nokukhulelwa kanye lactation.
2. Futhi hhayi Kunconywa ukusebenzisa abantu abanomlando elokugula ngengqondo efakwe ohlwini.
3. Ezimweni hypersensitivity kuya varenicline izidakamizwa azikwazi kubhekwe.

Ngaphezu kwalokho, ukubhema "varenicline" amaphilisi akufanele kuthathwe:

1. Intsha azifinyelelanga engu-18 ubudala.
2. Abashayeli nama-pilot. Kusukela izidakamizwa kusiza ekwehliseni ukunakwa.
3. Abantu abaku- komsebenzi okuphathelene izindlela ngqo. Isizathu iyona Izimo efanayo - ukungakwazi ukugxilisa, futhi isikhathi eside.

side effects

Kufanele uqaphele ukuthatha amaphilisi ngokumelene ukubhema "varenicline". Izibuyekezo wangaphambili ababhemayo basikisela ukuthi ngesikhatsi ukwelashwa abazizwa ukukhathazeka engaqondakali, ukungahlaliseki. Kwakukhona kaningi ukuqwasha. Ngomqondo onabile, zonke lezi zimpawu akufanele okwesabisa wena. Phela, nabo basuke evame ukubuzwa yibo bonke ngubani ayeke ukubhema, ngisho ngaphandle asebenzise izidakamizwa. Ngezinye izikhathi ungase ubone high blood pressure, abafundi osuke usuvulekile. Libuye mkhuba ngempela kuyaqondakala ukuthi senzeka, kubalulekile ukuba ahlanze umzimba nicotine. Nokho, kukhona kakhulu emibi. Ngokwesibonelo, ezifana:

• Ancishisiwe ukuzwa ethintekayo.
• Tachycardia.
• Ukuvuvukala ulimi noma umphimbo.
• Imisipha zibe.
• Ngamaphupho nje la.
• Ukuhlanza, noma isigqiki wezimpi ezalandela.
• Exacerbation kwezifo ezihlukahlukene, ukunqotshwa njalo izifo ezibangelwa amagciwane.

Njengoba nje ubona ngaso nezimpawu ezifanayo, kumelwe ngokushesha ayeke ukuthatha izidakamizwa kanye nodokotela. Udokotela kuyokusiza ukuba ulungise umthamo. Kungenzeka ukunciphisa ke. Khona-ke emzimbeni kuyoba lula ukujwayela ukuba ukungabi nicotine.

Ukusetshenziswa "varenicline" amaphilisi

Inzuzo enkulu yale imithi yokuthi awudingi ukuba ngiyeke ukubhema esithubeni nje. Lokhu kusho ukuthi umuntu ukucindezeleka kuyancipha. Unganikeza ukubhema bese, lapho kuzodlula ngokuphelele yonke inkambo yokuhle. Kodwa ochwepheshe batusa ukuba bayakhohlwa isifiso ukwenza yobunzima engxenyeni sesibili sokwelashwa.

Kungcono oyi-lokuzinqumela usuku lapho unquma ukuyeka ugwayi. Odokotela bengqondo Sisikisela ngokukhetha ngosuku elalinikezelwe yimuphi umcimbi obalulekile ngawe. Qala ukuthatha izidakamizwa kungenzeka ngesonto ngaphambi kosuku ekhethiwe.

Zonke "varenicline" amaphilisi zibaliwe. Inikeza lula esengeziwe ngokuvumela ukuzulazula, lapho futhi hlobo luni ithebhulethi kuwufanele ukuthatha.

I umthamo lwemithi "varenicline"

Ufuna nje ukusho ukuthi imithi oyinikiwe linezinsuku ezingu-84. Ngezinye izikhathi futhi zibeka Yiqiniso ezingeziwe isikhathi esifanayo (amasonto 12). Uma ngenxa ukuphathwa awuzange yibona abathole imiphumela efiselekayo, udokotela wakho angase akunikeze inkambo yesibili esemqoka.

amaphilisi kungaba ngasiphi isikhathi, kungakhathaliseki ukuthi ukudla. Ngakho kufanele nge ingilazi egcwele amanzi. Yindlela uzobe kangcono amuncwa wumzimba.

Kukhona nokushintsha kokudla nokufakwa lwemithi ekhethekile:

• Eyokuqala 3 izinsuku uthatha 1 emhlophe iphilisi kanye ngosuku.
• Ezinsukwini ezingu-4 umthamo luyanda. Kuzodingeka ukuthi baphuze 1 iphilisi ezimhlophe izikhathi 2 ngosuku. Phakathi nale nkathi, kuyinto efiselekayo ukunciphisa inani osikilidi ngibhema ngosuku.
• Ezalandela amasonto 11, udla 1 blue ithebhulethi kabili ngelanga. Ngokuvamile, ngaleso sikhathi umzimba isivele ingashintshwa ngokugcwele izidakamizwa, imiphumela emibi kuyehla. Ngalesi sikhathi kubalulekile ukuba ekugcineni ukuyeka ukubhema.
• Phakathi udinga ukusebenzisa i amaphilisi ezengeziwe blue kabili ngosuku.

Kuleso simo, uma wesaba ukuthi umkhuba imithi oyinikiwe ngeke ziphele ngokuphelele, kungase kungabi ngokushesha ayeke ukuthatha amaphilisi, futhi kancane kancane ukunciphisa umthamo varenicline. Ngaphezu kwalokho, le ndlela yokukhulisa kwelashwa ukwazi ukuvimbela izibonakaliso ubudlova akunasidingo, ukuqwasha, ukucindezeleka kuwukubonakaliswa okungase, uma evele ukuyeka ukuphuza umuthi.

Asebekhulile kanye neziguli kanye kwezinso kahle futhi umsebenzi hepatic, ushintsho umthamo in inamba yezimo akudingekile. Nokho, uma imiphumela emibi kakhulu, kufanele kudokotela. Njengomthetho, kunciphisa umthamo engxenyeni ukuphathwa yesibili iphilisi elilodwa ngelanga.

Iseluleko Professional: kanjani ukuyeka ukubhema

zokusebenza kwengqondo eziningi zithi kungakhathaliseki ukuthi ngempumelelo noma wayekujabulela lokhu izidakamizwa, kungase abe namandla ekulweni ukubhema. Lapha kuyafaneleka uhlalisa kuhle okutjhiwo ukuhlakanipha Folk: "Ngo-" varenicline "ithemba, kodwa labo ukuzisiza." Iqiniso liwukuthi ukuze kuzuzwe imiphumela emihle, kudingeka ukuba isifiso sakho kanye nogqozi. izifundo lwezenhlalo wabonisa kanjani ukuthi ukuphathwa ngempumelelo kakhulu kulabo ezigulini eziye sina ukuyeka ukubhema.

Okunye okubalulekile kuleli cala futhi ukusekela nabathandekayo, osebenza nabo, abantu obajwayele. Uma othile nawe abheme ugwayi, ungakwazi kalula aphule. Ngakho-ke kuyadingeka ukunciphisa noma uxoxe nabantu abanjalo esiphansi, noma ushiye ngesikhathi intuthu amakhefu kude endaweni ethile kude.

Khetha: "varenicline" noma "Tabeks"

Phakathi "varenicline" analogs kuhlanganise izidakamizwa ezifana "Tabeks". Abaningi bakhetha igama lakhe, ngoba ushibhile. Kodwa zokwelapha luye lwabonisa ukuthi cytisine (ngesisekelo okwenziwé okulingana) usebenza ngaphansi kahle kuka varenicline. Uma sisetshenziswa "varenicline" umuntu has ukuya osikilidi, futhi, njengoba umthetho, kuba kubo ukubuyiselwa engasekho. Lena sakhiwo sesimanjemanje kakhulu futhi kahle. Kuwufanele ke Yiqiniso, okuningi eqolo "Tabex".

Inani amaphakheji ezimbili, equkethe amaphilisi 11 500 mg kanye amaphilisi 14 mg 1 ruble 1300-1400. Amaphilisi mg 112 1 ubeke ruble mayelana 3200. Yiqiniso, izindleko zingahluka ezindaweni ezahlukene.

Mhlawumbe othile "varenicline" amaphilisi kubonakale ebiza kakhulu, kodwa eqinisweni okwase kuyisikhathi eside kwaziwa ukuthi impilo yabo kungcono hhayi ukusindisa.