'Immunoglobulin womuntu' Ukushushumbisa.

Ukusetshenziswa kwezidakamizwa "immunoglobulin womuntu" njengoba izidakamizwa kuvamile manje kakhulu zokwelapha. Yabela it in iziyaluyalu we omzimba noma iyiphi imvelaphi.

Lo muthi - ke imithi immunobiological, a immunoglobulin womuntu polyvalent kakhulu. Nazi ezinye izimpawu ukusetshenziswa kwe-ejenti eyenza imithi:

- Primary noma immunodeficiency yesibili (njengoba replacement therapy);

- thrombocytopenic purpura ;

- ngamagciwane okunzima (kuhlanganise sepsis) kubangelwa ejenti webhaktheriya;

- Guillain-Barre syndrome;

- kwavela ngaphansi kwethonya ukusabela sokuhlasela kwamasosha omzimba, ukuntuleka kwegazi emzimbeni;

- (sokuhlasela kwamasosha omzimba) mkhakha okhethekile hemophilia.

Imibandela ngenhla sokugembula kukhona eyisisekelo, lapho imithi "immunoglobulin womuntu" inikezwa njengendlela yokwelapha. Kufanele kuqashelwe ukuthi ukulungiselela isetjentiswe, futhi njengendlela yokuthola ekuvimbeleni izifo eziningi. Ngakho, nomuthi "immunoglobulin womuntu" kuboniswa ukulapha nge cytostatics ebukhoneni immunodeficiencies ahlukahlukene etiologies (ukuvimbela ukuthi kungenzeka isifo esibi kakhulu) ngezindleko eziphansi isisindo osanda kuzalwa (ngaphansi kuka-1500 amagremu), futhi usongo ukuthuthukiswa isisu umkhuba.

Kukhona ezinye izici izidakamizwa, ulwazi okuyilona elidingekayo ukuze umuntu ukuqonda izidakamizwa ngenxa umthelela izinguquko. I nomuthi "immunoglobulin womuntu" lapho zaphathwa ngemithambo yegazi akakwazi ukuba zisakazwe ngokulinganayo wonke umzimba ngokushesha. Le nqubo ithatha i isilinganiso izinsuku eziyisithupha kuya kweziyisikhombisa. Iningi izidakamizwa (90%) we monomer emelelwa IgG, asele 10% zimumethe dimers immunoglobulin, ayisiza G, A no M. Ubude ukuphikelela emzimbeni izidakamizwa iqondiswa izinsuku ezingaphezu kwamashumi amane, okwakubonisa ukulondolozwa eside we umphumela omuhle izidakamizwa.

I umthamo we-ejenti ezithaka imithi kuyinto ziyahlukahluka kakhulu futhi inqunywa isifo, namandla aso kanye izici ngamunye zomzimba womuntu. Ngenxa yalesi sizathu, nika ejenti "Immunoglobulin muntu ovamile" kumelwe udokotela. Self-zokuphatha izidakamizwa e umthamo wakhe ngokungenasizathu kungamukeleki.

Izimo lapho uya khona kuyinto ukutholakala nomuthi Isiguli immunoglobulin ukuntula A, kubangelwa inqubo sokuhlasela kwamasosha omzimba, okusho ukuthi, khona amasosha omzimba esisheshayo kuya globulin.

Ngayilungiselela "Immunoglobulin" ka-plasma kubaxhasi, aphethwe eziningana zokwelapha (ukuqinisekisa ukungabi kuwo izifo ezingase zidlulele ngegazi).

Imiphumela engemihle, khona lapho okungukuthi ngokuvamile kuqashelwe, iziguli ngokuyisisekelo ethulwa ejwayelekile izidakamizwa (nesiyezi, ikhanda) futhi ngezikhathi ezithile - atypical (tachycardia, hypotension, dyspnea, cyanosis, myalgia, Ukugodola). It akuvamile waphawula ukuthuthukiswa komzimba nezinto emuthini, ephelezelwa hypotension, nciphisa futhi nokulahlekelwa ukwazi.

Isiyazanywa izidakamizwa "immunoglobulin Human 'awazange olwenziwa kwabesifazane abakhulelwe (ngesikhathi lactation), ngakho kufanele ugweme enquma izidakamizwa iziguli anjalo. Phela, akwaziwa nokuthi sizokuthinta kanjani ezingenzeka embungwini, futhi grudnichka.

Ngakho, lesi sidakamizwa "immunoglobulin Human" namuhla kuyindlela yokuthola "inombolo eyodwa" ukuze ukwelashwa kanye nokuvimbela izifo ezibangelwa amagciwane ezihlobene nokungawuvivinyi ngokwanele amabutho zokuzivikela kwesimiso somzimba sokuzivikela ezifweni. Ukusetshenziswa Its zokwelapha zanamuhla ubani oye kakhulu sinciphise tigameko izifo zemigudu yokuphefumula, sokuhlasela kwamasosha omzimba nezifo immunodeficiency.