Imithi "Lasix": izinkomba ukusetshenziswa, Izimo, kanye nokubuyekeza

Okubizela lesi sidakamizwa "Lasix"? Izinkomba ukusetshenziswa zomuthi uzobe ezibalwe ngezansi. Ngaphezu kwalokho, sizokutshela lokho Izimo zidingidwa ifomu izidakamizwa lapho kukhiqizwa, lokho kuyingxenye yesizathu ke, uma kuye kwadingeka yini imiphumela emibi futhi analogue.

Ukwakheka kanye ukuma

Okwamanje, ukuthengwa angabhekwa wokulungiselela e amafomu alandelayo:

• "Lasix" amaphilisi-mbumbulu. Izibuyekezo bathi asemhlophe, isiyingi futhi ingozi phakathi. Isithako asebenzayo we nomuthi kuyinto furosemide. Lihlanganisa izingxenye asizayo ngesimo lactose, isitashi, isitashi pregelatinized, talc, Silicon dioxide colloidal kanye magnesium stearate. imithi Itholakala mixer emapheshana we aluminium ucwecwe, okuyinto ezibekwe amakhadibhodi emaphaketheni.
• Isixazululo kwezokuphatha esicutshini noma emthanjeni "Lasix" (ampoules). Ukufundiswa uthi element lamanje le fomu furosemide.

Izici zomuthi

Uyini izidakamizwa "Lasix"? Izinkomba ukusetshenziswa zomuthi ezichazwe imiyalelo afakiwe. It is amisiwe abuye lo mshini wezenzo izidakamizwa.

"Lasix" - isisu okusheshayo futhi nginamandla, okuyinto esuselwe sulfonamide. It amabhlogo ohlelweni zokuthutha sodium kanye chloride ion ku obukhulu inyuka esitho of Henle division iluphu. Ngakho, umphumela isisu zomuthi incike ekwamukelweni yayo mafutha anciphisa isikhala esingaphakathi we tubules kwezinso.

imiphumela yesibili zomuthi bayanda uketshezi potassium ku distal tubule izingxenye kanye nomchamo okukhiphayo.

ukwelashwa Course nomsebenzi izidakamizwa isisu akuyona encishisiwe. Ngo senhliziyo, lesi sidakamizwa "Lasix" angabacwasi ngokushesha kunciphisa Layisha, kanye ingcindezi ku Umthambo yamaphaphu futhi i-ventricle engakwesobunxele.

nomuthi Okubukwe has inciphise umfutho wegazi ophakeme, okuyinto kubangelwa ukwanda sodium excretion, igazi ivolumu ephansi futhi ukwehla bushelelezi imisipha ukuphendula.

Pharmacokinetics

"Lasix" - isisu, okuyinto ngokushesha ugxile kusukela pheshana emathunjini. bioavailability wayo zabantu ezahlukene zingancishiswa 30%. Lokhu kungenxa yokuthi kungangena ngokuphelele zonke izici, kuhlanganise isifo ecashile.

Umuthi sibopha kahle plasma amaprotheni (cishe 98%). It uboniswa ifomu ingashintshiwe nge nezinso ngokusebenzisa emathunjini.

Kufanele kuphawulwe ukuthi "Furosemide" Bufinyelela kuhle ngokusebenzisa isithiyo esinomhlapho futhi excreted nge ubisi lwebele.

Izidakamizwa "Lasix" (imijovo): izinkomba ukusetshenziswa

Yikuphi izifo angabelwa ukuba imithi ngesimo isixazululo? Ngokwe-ukulungiselela imfundo 'Lasix "(analogue izokwethulwa ngezansi) isetshenziswa:

• Edema syndrome yinhliziyo (ezingamahlalakhona);
• ubuchopho edema;
• Edema syndrome nokwehluleka kwezinso (ezingamahlalakhona);
• Inkinga abanomfutho wegazi ophakeme;
• acute esingamahlalakhona kwezinso, kuhlanganise nalezo ebonwe ukusha nokukhulelwa (ngoba uketshezi ukwesekwa excretion);
• Edema syndrome nephrotic syndrome;
• nomfutho wegazi ophezulu;
• Edema sifo ngo isifo sesibindi,
• njengozime ubuthi ophoqelelwe amakhemikhali diuresis ukuthi izinso ngefomu zinjalo.

Tablets "Lasix": izinkomba ukusetshenziswa

Kufanele uthathe isidakamizwa ngezizathu ezifanayo eziye ezichazwe ngenhla ngesimo amaphilisi. Nokho, ochwepheshe bathi ngoba esicutshini noma ekuphathweni emthanjeni, ikhambi efakazela kuphumelela kangcono.

Izimo

Yini isimo lesiguli asivunyelwe ukuthatha "Lasix"? Izimo ukusetshenziswa kwalo mkhiqizo ahlelwe imiyalelo afakiwe. Cabanga manje:

• hyponatremia ezinzima;
• ukwehluleka kwezinso nge anuria;
• ukudakwa digitalis;
• precoma hepatic futhi equlekile;
• glomerulonephritis acute ;
• hypokalemia ezinzima;
• ngesikhathi sokukhulelwa;
• hypovolemia noma ukuphelelwa amanzi emzimbeni;
• ibele;
• uzwakalise thuthuva outflow umchamo;
• hyperuricemia;
• mitral decompensated futhi stenosis yomthambo i-aorta ne-hypertrophic zenhliziyo obstructive;
• Izingane ezingaphansi kweminyaka emithathu (ifomu tablet);
• isigqugquzeli emaphakathi ingcindezi emithambo yegazi;
• hypersensitivity kuya izidakamizwa;
• yokungezwani komzimba ukuze furosemide.

Isikali Jikelele zomuthi nezindlela zayo ukusetshenziswa

Indlela "Lasix"? Umthamo zomuthi incike inhlobo yesifo.

Tablets kufanele libhekwa lilonke, esiswini esingenalutho. Ngo ukuqokwa izidakamizwa kumele kusetshenziswe at umthamo ubuncane ukuthi yanele ukuba sifinyelele nomphumela oqabulayo.

I Kunconywa umthamo esiphezulu ngelanga abadala kuyinto 1500 mg. Ezinganeni, incike isisindo isiguli (2 mg / kg, kodwa hhayi ngaphezulu kuka-40 mg ngelanga). Isikhathi yokwelapha kunqunywa nguchwepheshe umuntu ngamunye futhi lincike ubufakazi.

side effects

Manje uyazi ukuthi ukuthatha "Lasix". Sebenzisa le izidakamizwa kumele udokotela. Lokhu kungenxa yokuthi it has a inombolo kahle esikhulu ka ukusabela ezingezinhle. Cabanga uhlu kubo njengamanje.

• ikhanda, ukuba buthakathaka kwezicubu, ukudideka, ukushaya kwenhliziyo okungajwayelekile, ukuquleka;
• somnolence, dyspepsia, ubuthakathaka, nciphisa, nomlomo owomile;
• hypomagnesemia, chloropenia, hyponatremia, hypocalcemia, hypokalemia, alkalosis umzimba;
• isiyezi, kwehle ukubekezelelana glucose, anda amazinga serum of triglyceride cholesterol;
• isicanucanu, hematuria, ukuhlanza, ngokweqile ukwehlisa wegazi, kwehle potency;
• uhudo, ukulahlekelwa kukuzwa, ukuqunjelwa, tinnitus, nephrotic syndrome;
• komzimba: nephritis interstitial, pruritus, leukopenia, urticaria, dermatitis exfoliative, bullous Izilonda, imfiva, erythema polymorphic, eosinophilia, purpura, vasculitis, photosensitivity;
• agranulocytosis, thrombocytopenia, hemolytic noma unenkinga yegazi eliphansi aplastic.

izidakamizwa ekuhlanganyeleni

Ngokwe-ukulungiselela imfundo 'Lasix "izilinganiso okuyinto ethulwa lapha, izidakamizwa ekuhlanganyeleni ezilandelayo:

• "Carbenoxolone" ama kanye iliquorice ngemithamo ezinkulu kanye nokusetshenziswa nokunwetshiwe ka laxatives lihambisana furosemide kwandisa ingozi yokungenwa hypokalemia.
• Izidakamizwa ne umphumela nephrotoxic okwandisa ingozi nemiphumela nephrotoxic.
• Aminoglycosides ngenkathi usebenzisa furosemide kwandisa ingozi yokungenwa nephrotoxicity futhi ototoxicity isinyathelo kuqala.
• ebulilini cephalosporins kwandisa ingozi yokungenwa nephrotoxicity.
• Ama-NSAID futhi acetylsalicylic ene-asidi anciphisa umphumela isisu of furosemide.
• "Phenytoin" kunciphisa umphumela isisu of furosemide.
• "Methotrexate" futhi "Probenecid" ukunciphisa imithelela furosemide.
• Nge inhlanganisela "Cyclosporin A" ne furosemide kwengozi arthritis gouty.

izincomo Specific ukusetshenziswa zomuthi

Ngaphambi kokusebenzisa umkhiqizo "Lasix", izinkomba lapho banikezwe ngenhla, kubalulekile ukukhipha khona iziyaluyalu imakwe umchamo outflow.

Phakathi ukwelashwa kufanele kube zokuqapha njalo ka serum lokuhlala potassium, i-sodium, futhi creatinine.

Ekwelapheni "Lasix" kungcono udle ukudla okunothile potassium. Kwezinye izimo kungase kube edonsa izidakamizwa potassium-engashiyi Kunconywa.

Analogs nomuthi

Bezakhiwe analogue izidakamizwa kubhekwe (ejenti asebenzayo) yizidakamizwa ezifana "Furosemide", "Furon" futhi "Fursemid". Futhi imithi "Lasix" Ungashintshanisa "Akripamidom", "Brinaldiksom", "veroshpiron", "hydrochlorothiazide", "Diuverom", "Indap", "Klopamid", "Lorvasom," "mannitol", "Spironolom", "Uraktonom" futhi neminye imithi.

Nobufakazi mayelana izidakamizwa

Manje, niyazi, lokho ngezinhloso ebekiwe imithi "Lasix". Izinkomba ukusetshenziswa kwalesi izidakamizwa ziye achazwe ngenhla. Yini iziguli uthini ngaye? Cishe bonke abantu ngokuthatha imithi, uqaphele kahle yaso ephezulu. Nokho, iziguli eziningi esekhala inqwaba ukusabela ezingezinhle (ikhanda elibuhlungu, isicanucanu, njll). Nokho, ochwepheshe bathi uma uthatha ngemithamo sakugcina miphumela ezingajwayelekile kakhulu.