"Chloramphenicol" - ngeso lehla. Yokusetshenziswa

Njengoba izifo ezithathelwana iso bavame ukusebenzisa izidakamizwa "Chloramphenicol". Ngokuba amehlo ingenye indlela ephumelela kunazo zonke iqhaza ukuba banqobe isenzo microorganism elimazayo. Drops equkethe 0.25% ingxube chloramphenicol, okuyinto isakhi esiyinhloko esebenzayo zomuthi. Chloramphenicol ngokuvamile ekhiqizwa yizimboni in vials equkethe 5 ml we ketshezi okusebenzayo iphakethe isitaki futhi cap weThrojani.

Izidakamizwa "Chloramphenicol" (iso amaconsi) umyalelo elizibiza ngokuthi ama-antibiotic engasetshenziswa ukwelapha anhlobonhlobo izifo. It has umsebenzi elwa namagciwane.

Chloramphenicol anezakhi okunikeza nomphumela bacteriostatic nomsebenzi omkhulu zomuthi ngokumelene eziningi amagciwane Gram-HIV futhi Gram-negative: Staphylococcus SPP, Neisseria gonorrhoeae, Shigella SPP .. kanye nabanye. Ingqikithi Umsebenzi ngokumelene zamagciwane nokuthi ngokuvamile amelana penicillins. Ngakolunye uhlangothi, kwakheka ukumelana nezilwanyana ezincane yingozi chloramphenicol kancane kakhulu.

I izakhiwo pharmacokinetic zomuthi "Chloramphenicol" (ngeso amaconsi) umyalelo ephawula kanje. Lapho ethola izingxenye zakhe zokusebenzisa izidakamizwa ngokushesha futhi cishe ngokuphelele ugxile kusukela pheshana emathunjini. Ngaphezu kwalokho, bioavailability salo 80%. Umuthi unekhono ngokushesha basakaza emzimbeni. Izinga chloramphenicol sesibopho ukuthobisa plasma amaprotheni kuyinto 50-60% futhi metabolization yayo esibindini. isigamu-ukuphila main izidakamizwa esebenzayo umuthi amahora mayelana 1.5-3.5, futhi mhlawumbe eyenziwa excretion umchamo.

Umuthi 'Chloramphenicol "(ngeso amaconsi) isitatimende incoma ukuthi kwenzeka zezifo ezithathelwanayo namakhambi ukuvuvukala okubangelwa nezilwanyana ezincane nozwelo chloramphenicol. Lokhu, ngaphezu kwakho konke, i-typhoid fever, uhudo, ukukhwehlela whooping, trachoma. izidakamizwa ekwelapheni i-pneumonia, meningitis nezinye izilonda zaso.

Ekwelapheni Izilonda suppurative, amathumba, izilonda trophic kanye ukusha, njengoba umthetho, umuthi isetshenziswa njengenhlangano agent yangaphandle. Ukuze izidakamizwa nezokusigcoba wabonisa for ekwelapheni izifo ocular ukuvuvukala.

Ngo kuqokwa izidakamizwa Kunconywa ukuthi umuntu umthamo lwemithi. Kubantu abadala, umthamo we izidakamizwa mg 500 at ezintathu-inani eliphindwe kane reception usuku olulodwa. Ezinganeni kunconywa ukusebenzisa umahluko, kuye ngokuthi isisindo sengane kanye nobudala.

Ngoba abantwana kuze iminyaka 3, umthamo watusa kuyinto 15 mg ngayinye 1 kg esisindo, eyenzelwe izingane ezineminyaka engu eminyakeni emithathu kuya kweziyisishiyagalombili - 150-200 mg, futhi izingane ezindala, umthamo kuyinto 200-400 mg. Kuzo zonke izimo, imithi kufanele kuthathwe kathathu noma kane phakathi kwezinsuku ezingu-7-10.

Lapho isicelo ihlelwe ngokulandelana kwezihloko isicelo umuthi gauze pads noma ngqo on endaweni ethintekile. Ligation kulokhu kwenziwa ngezikhawu ezingu-1-3 of.

Chloramphenicol (ngeso amaconsi) Umhlahlandlela uncoma ukusetshenziswa ekwelapheni izifo amehlo e ohlotsheni eziyinkimbinkimbi zokwelapha.

Lesi sidakamizwa kungadala imiphumela emibi. Qondisa amaphuzu kungenzeka okuvela anaemia aplastic, isicanucanu, ukuhlanza, ngokuvamile ingaba bekhanda isilungisiwe. Ezimweni ezingavamile, lapho sididekile, delirium, ukuhhema ezahlukene, labo ababebanga ukuba ngeso lehla "Chloramphenicol". Izibuyekezo iziguli abaphuza umuthi, ethi phakathi reception kungenzeka ukuqubuka nezinye ezintweni ezenzeka ngaphandle.

Musa ukuphuza imithi kubantu abaye kwatholakala yezifo igazi esikhumbeni, abesifazane abakhulelwe kanye nezingane kuze kube iminyaka emithathu.

isizathu esikhethekile sokuba kukhulunywe kufanele baqaphe e ukusetshenziswa kwezidakamizwa e ezigulini eziye kwadingeka ngaphambi ukwelashwa amaseshini izidakamizwa cytotoxic futhi radiotherapy izikhathi.

Nge ukusetshenziswa ngesikhathi esisodwa nge-penicillin akuzange chloramphenicol esiphazamisayo kungani leso senzo sabo amagciwane.