Antiulcer izidakamizwa 'Omez', izinkomba ukusetshenziswa, side effects

Antiulcer nomuthi "Omez" kungokwalabo iqembu inhibitor Izidakamizwa. izidakamizwa Active - asizayo omeprazole - disodium edetate kanye sodium hydroxide. Lo mshini wezenzo ka omeprazole kusekelwe ekuvimbeni uketshezi of hydrochloric acid e esigabeni sokugcina futhi ngenxa yalokho, ukuncishiswa acid. Ngenxa omeprazole prodrug icushiwe ku esiswini acid medium. Phakathi namahora angu-ngemva kokuthatha 20 g le-ejenti e iziguli umphumela antisecretory siqala ukuvela, futhi liyaqhubeka usuku lonke. Omunye reception kumanele okusheshayo ukucindezelwa yansuku zonke uketshezi esiswini, nokwelashwa kwayo esiphezulu imiphumela ngosuku 4.

I asebenzayo izidakamizwa omeprazole ngesimo granules, ngakho ukumuncwa yayo kwenzeka kuphela emathunjini kanye esiphezulu ihora elilodwa siyenzeka ngesikhathi emakamu esiphezulu plasma nomuthi "Omez". Ukufingqa amaphuzu bioavailability yakhe hhayi eliphezulu kakhulu 40%. Iningi izidakamizwa excreted ku umchamo (80%), lonke - e Bile (20%). Ukukwenza umkhuba ezahlukene pharmacokinetics kwasebekhulile, kukhona ukwehla imvume izidakamizwa i-bioavailability anda.

Lapho kuhlolwa isiguli of peptic isilonda isifo, ubhekwa izindlela eziphumelelayo ukulungiselela "Omez" izinkomba ngokusetshenziswa imithi Kunconywa ekwelapheni izilonda esiswini kanye duodenal, kanye nokuvimbela kokushelela. Ngo kokutshelwa ngokukhubazeka kwengane ngokuvamile iqondiswa izidakamizwa ngomlomo kungaqali, futhi ngesimo ukumnika emthanjeni e isamba 40 mg.

Kukhona izifo lapho umthamo wansuku zonke kumele kunyuke "Omez" izidakamizwa, izinkomba ukusetshenziswa ezimweni ezinjalo aqukethe uphethwe giparsekretornyh uthi, ikakhulukazi Zollinger-Ellison syndrome. Umthamo kokuqala kule zokugula 60 mg, is ngamunye ifaniswe isiguli ngasinye, futhi ngezinye izikhathi seqiwe ufinyelela engayitholi nsuku zonke mg 120. Ezimweni ezinjalo, kufanele ihlukaniswe infusions eziningana ngosuku.

Ngezinye umthamo 40 mg, futhi efanayo amahora 2 ngaphambi nokuphathwa ejenti izinzwa iqondiswa "Omez" izinkomba ezihlanganisa ukusetshenziswa Mendelson Syndrome. Okungukuthi, ohlotsheni umthamo kubhekwa eliphezulu ekuvimbeleni ingress nokuvinjelwa esiswini acid imvelo e yomoya phakathi nokuhlinzwa.

Isheduli umuntu ukuthola nomuthi "Omez" okubonisa ukuthi isicelo ingahlanganisa izifo elandelayo:

- Reflux esophagitis;

- NSAID gastropathy.

Ngokucophelela ukuba sikuqonde yokwamukela izidakamizwa ngenxa engemihle. ukubonakaliswa yabo kungenzeka omzimba izinhlelo ezithile. Kuhlelo hematopoietic, kukhona imiphumela emibi ngesimo leukopenia, pancytopenia, thrombocytopenia futhi agranulocytosis.

Isimiso sokugaya ukudla bungene ngokuvamile esabela ngayo izidakamizwa "Omez" ukubukeka ukuqunjelwa noma isifo sohudo, ukuqumba, isicanucanu nokuhlanza, ukunambitheka thuthuva. Ngo ezinzima esingamahlalakhona hepatic ngezinye izikhathi senziwa -hepatitis (i-jaundice kanye).

CNS futhi ngokuvamile usabela kabi le reception "Omez" izidakamizwa kubonakala isiyezi, ukucindezeleka kanye nobuhlungu. Uma ukusetshenziswa kwalesi izidakamizwa e isiguli kwandulelwe ezinzima isibindi isifo, ukuze kube khona encephalopathy.

Akuvamile bephawula ukusabela dermatological kanye iguliswa nge ukubonakaliswa ezahlukene.

Abstract "Omez" has Izimo eziningana. Umhlahlandlela uxwayisa ukwehluleka ukwelashwa ngesikhathi sokukhulelwa, lactation kanye ebuntwaneni, ngakho akufanele yini ukuthatha izidakamizwa ukuze abantu hypersensitivity kuya asebenzayo izidakamizwa omeprazole. Ngo izidakamizwa ukweqisa izidakamizwa esetshenziswa ekwelashweni lingaze, hemodialysis kulokhu akuyona ngempumelelo.

Gcina lokhu imithi "Omez" akufanele kube iminyaka engaphezu kuka-2 endaweni epholile, kude nezingane.