Analogs "Atoris": incazelo, ukubuyekezwa

Izidakamizwa "Atoris" kubhaliswe njengoba imikhiqizo lenkampani Slovenian eyenza imithi "Krka". Kuyimfanelo futhi ezingabizi ejwayelekile "atorvastatin", elalikade kuphela wathengiswa abe izidakamizwa Pfizer 'Lipitor'. Okwamanje, analogs yayo ( "Atoris", "Torvakard" kanye nabanye) ziye zaba ingxenye umkhuba emtholampilo futhi izinga zingabameleli hypocholesterolemic.

Ukukhishwa

Ukulungiselela "Atoris" itholakala izibhebhe ezintathu iyunithi imithamo. Lokhu 10, 20 no-40 mg. Kuthengiswe emabhokisini, ngendawo yokuhlala amaphilisi ibhamuza. Umthamo ngamabhokisi 10, 30 no-90 'Atoris "amaphilisi (imfundo manual). Analogs izidakamizwa ejwayelekile futhi ingase iqukathe amanani afanayo lomcebo esebenzayo, kodwa akanawo nomphumela ofanayo ngenxa umehluko yezingxenye.

Umuthi 'Atoris "

Ingqikithi esebenzayo atorvastatin, statin III isizukulwane. izinto Asizayo yilezi ezilandelayo: polyvinyl utshwala, ama-titanium dioxide, macrogol 3000, magnesium stearate, talc, sodium croscarmellose, microcrystalline cellulose, monohydrate lactose, povidone, i-calcium carbonate, sodium lauryl sulfate.

Excipients kunqunywa tableted ngomthamo ifomu futhi ukuthola izinga atorvastatin ukumuncwa emgudwini wegazi. Ngakho, noma iyiphi imithi analog "Atoris" kumele siqukathe umthamo ofanayo lomcebo asebenzayo akhululwa futhi ngezinga elifanayo, ukudala efanayo igazi lokuhlala.

Ukulungisiswa statin futhi izidakamizwa "Atoris"

Ukulungiselela "Atoris" njengoba izidakamizwa esebenzayo yakhiwa atorvastatin. It kungokwalabo isigaba oyisizukulwane sesithathu ejenti. Nge lwalumumethe eziningi izifundo ukuthi isikuqinisekisile zibheke reception yayo khona isifo sokuqina kwemithambo yegazi engcupheni noma lasavele asungule lesi sifo. "Atorvastatin" analogs, "Atoris" nezinye statin kakhulu ukunciphisa ikhono ongaphakeme ukuminyana lipoproteins (LDL) ukubangela isifo sokuqina kwemithambo yegazi kanye kuholele okubi kakhulu yayo. Lena value abo zokwelapha, ngoba nge ukuhileleka kwabo ngqo kunciphisa tigameko yokuhlaselwa yinhliziyo.

imiphumela kwemithi

Umphumela ebaluleke kakhulu yokuthola ukucindezeleka cholesterol zamagama ngu ezivimbela enzyme HMG-CoA reductase. Imiphumela iba yinhlanganisela yokukhandleka ekunqanyulweni noma ukunciphisa okuphawulekayo synthesis LDL. Le ngxenyana encane lipoproteins avuse isifo sokuqina kwemithambo yegazi, izimbangela olugcwele odongeni futhi usigcine yayo imithambo ye inhliziyo, ubuchopho, izingalo nemilenze aphansi. Kanye nokwehlisa LDL kwandisa lokuhlushwa eliphezulu kwabantu lipoproteins.

Zenza umsebenzi obalulekile: anda ulwelwesi ukumelana amathonya mechanical futhi amakhemikhali ngenxa ukuqala cholesterol kuwo. Ngakho, HDL ilahlwe, kodwa musa buthelela cholesterol. LDL asihole ekuqongeleleni yayo ngemuva endothelium semithambo, okubangela ukuqina kwemithambo yegazi, kuyilapho Isidlulisilwazi Esilula cholesterol ezifakwa wehlise izinga, kodwa musa okukhipha ke kusukela kwangaphakathi igobolondo Umthambo uhlobo nokunwebeka.

Sokuphuzisa "Atoris" ukulungiselela

Izincomo sendlela ukuthatha "Atoris" ubilise phansi ukucacisa ezinye izici. Ikakhulu, i-izidakamizwa esithathwayo umthamo ebekiwe kanye nsuku zonke ngemva kokudla kwakusihlwa ngaphambi kokulala. A umthamo owodwa kungaba 10, 20 no-40 mg. Njengoba umuthi kadokotela ngokuthenga yayo liyadingeka kudokotela. Lokho-ke ngemva ukuhlaziywa kanye nokuhlola lipid iphrofayela kukhishwa nezingxenyana ezithile Imininingwane igazi cholesterol uyakwazi ukuncoma umthamo efanele atorvastatin futhi analogs yayo noma isigaba ejwayelekile.

Lapho kokuqala cholesterol 7.5 ephakeme noma Kunconywa ukuthatha 80 mg / usuku. Isikali Okufanayo elibekelwe iziguli abaye bahlupheka a isilethikusebenza noma esigabeni okukhulu indawo yawo. Ngezinye lokuhlushwa 6.5 7.5 umthamo watusa 40 mg. 20 mg athathwe lapho izinga le-cholesterol 5.5 - 6.5 mmol / ilitha. 10 mg zomuthi ezifanele izingane kusukela eminyakeni eyi-10 kuya ku-17 nge hypercholesterolemia heterozygous, kanye nabantu abadala kanye hypercholesterolemia eyinhloko.

Izimfuneko imithi ejwayelekile

Qualitative Analogue "Atoris" ukulungiselela kufanele ibe unobuningi ezifanayo isithako esisebenzayo bese udala efanayo igazi lokuhlala. Kuncike ekutheni izindlela kuyinto esinjalo, kuyothathwa ngokuthi bioequivalent futhi Ungashintshanisa okoqobo. Mayelana izidakamizwa "Lipitor" kuyinto Analogue of "Atoris", wadala ngesisekelo atorvastatin.

Izimfuneko emitholampilo analogue "Atoris"

Noma yimuphi esikhundleni "Atoris", isigaba sakhe noma okulingana ukubunjwa, kufanele aqukethe statin. Kulokhu, ingasetshenziswa njengendlela okulingana ngokugcwele. Ngaphezu kwalokho, esikhundleni "Atoris" izidakamizwa Analogue kumele kwenziwe nge umthamo ehlosiwe wokusindisa. Uma usebenzisa 10 mg "Atoris", bese elinye izidakamizwa kufanele kube umsebenzi ofanayo noma ngaphezulu.

IsiZulu "Lipitor"

Kusukela atorvastatin yokuqala "Lipitor" zonke izidakamizwa kanye isithako efanayo esebenzayo akufanele ukuqhathanisa naye. Analogs, "Atoris" phakathi lapho olinganiselayo kakhulu intengo, futhi kufanele babhekwe kusukela lo mbono. Ngakho, kukhona imithi enjalo eliphakeme, nge okulingana kanye aphansi. Okugcwele analogue "Atoris":

• ezibizayo ( "Lipitor");
• ngokulinganayo kufinyeleleke ( "Torvakard", "Tulip");
• ushibhile ( "Lipromak", "Atomaks", "Lipoford", "Liptonorm").

Njengoba singabona, atorvastatin analogue kabanzi emelelwa. Izinkulungwane eziningi ezinikelwa yidolobha lase-low price isigaba. Lokhu kumele kufake eziningi imithi enegama ukuhweba "Atorvastatin", okuyinto akhiqizwa ngaphansi kwelayisense izinkampani ezinkulu ezithaka imithi.

Uma sifuna i Analogue of "Atoris" atorvastatin eshibhile yiliphi production ezifuywayo kungaphansi kwelayisensi. Kakhulu eliphezulu futhi nekuhambisana echazwe kuyinto "Atorvastatin" Borisov isitshalo kwemikhiqizo yasekhemisi, itholakala Belarus. Lapha, ukukhiqizwa zomuthi ilawulwa Krka, okuthela "Atoris".

Izici zomuthi esikhundleni

On umbuzo yini ukuba esikhundleni "Atoris", kubalulekile ukucabangela izimo eziningana. Okokuqala, izidakamizwa kufanele abe ngempumelelo emitholampilo ofanele futhi asibekezeleleki kahle. Okwesibili, amanani ayo kumelwe libe lincane, noma uma isigaba izidakamizwa iphathelene analogs kancane ngenhla. Okwesithathu, umthamo wangaphambili kufanele kwenziwe uma esikhundleni senziwe generic. Endabeni sithola ukuthi ukwedlulela kuleso i Analogue of isigaba izidakamizwa kubalulekile ukuthola i umthamo okulingana.

Indawo imithi ejwayelekile

Phakathi amalungiselelo equkethe atorvastatin, kukhona okulandelayo qualitative kakhulu: "Lipitor" "Torvakard", "Lipromak" futhi "Atoris". Analogs, ukubuyekezwa zazo iyivela kancane, akhiphe elibi kunalo kuwo nephephe. Yize bengabantwana preference intengo. Bangakwazi Kunconywa iziguli abangenandaba mayelana bioequivalence ka ejwayelekile noma engafuni overpay. umehluko Ibonakala umphumela lokhu ningagcini, nakuba izinga ukwelashwa ngezinga elithile abathintekayo.

Uma sicabangela atorvastatin ejwayelekile, kutuswa ongakhetha kuzo phakathi ngenhla. Kodwa, isibonelo, ukuze unqume ukuthi yikuphi ukukhetha - akulula, "Atoris" noma "Torvakard". Isizathu salokhu yilona ukuhambisana sekuyaphela nalezi izidakamizwa e intengo nokuphumelela kwaleso sembatho. Ngaphezu kwalokho, intengo futhi ngokuvamile efanayo. Ngaphezu kwazo ikhwalithi "Lipitor" futhi ngezansi - "Lipromak". Ngesikhathi esifanayo zokugcina, nge Umehluko omncane nje izithako, ethengekayo.

Yomiselela ekilasini nozakwabo "Atoris"

Lapho belungela ukuya khona "Atoris" analogue e-Ukraine nakwamanye amazwe CIS, kukhona ekilasini. Okungukuthi, abangabantwana ukulungiselela iqukethe omunye statin, ngokulandelana, nezakhi ezihlukene. Ushintsho enengqondo kunazo zonke "Atoris" ukuze "pitavastatin" noma "Rosuvastatin" ngezinga kancane LDL ukwehlisa. Lesi sakamuva kuphephe futhi ube nomphumela oqabulayo umthamo ephansi.

kumakhophi ngaphambili, kukhona "Atoris" kungcono ngaphezulu ukuqhathanisa nabo, nakuba nethonya emitholampilo ukuze afike ekugcineni. Ngokwesibonelo, "Simvastatin" - isidakamizwa ezingabizi kakhulu nge efakazelwe zokwelapha ukuphepha. Umthombo yokuqala 'Zocor'. Uma sicabangela ezingabizi futhi izinga isizukulwane wokugcina statin indawo "Atoris", kungcono ukuthatha isibonelo, "Merten". Lokhu engengaphansi Babetadisha 'Rosuvastatin "ejwayelekile nge intengo imali.