Protivoprotozoynoe kusho - kuyini? Isicelo kanye mshini wezenzo ejenti antiprotozoal

Uma udokotela wathola uke zokuthelela lenyama - amoeba, Giardia, Trichomonas, Plasmodium kuyinto ekwelapheni izifo ezibangwa kubo (uhudo, urethritis, coleitis, umalaleveva), yena uyomisa protivoprotozoynoe izindlela. Kuba njani kuthinta emzimbeni womuntu futhi isebenza kanjani, thina ngazo kulesi sihloko.

Indlela ohlukeneko antiprotozoal ejenti

Zonke izinto eziphilayo ngaphandle amagciwane ezihlobene eukaryotes. Okungukuthi kufanele isakhiwo Kuyi-nucleus amaseli. Ngakho-ke, babambeke umzimba nje babe umzimba Kuningi ukufana okukhona phakathi amangqamuzana amehlo ethu okuthiwa futhi balahle wabo nzima kakhulu kunokuba amagciwane. Futhi nje, ama-ejenti antiprotozoal (mshini wezenzo, sizoqhubeka sihlola Koto) ngokuvamile babe emzimbeni namandla umphumela anobuthi, okwenza kube nzima ukuba aphathe lesi sifo kwabanye. Kodwa ziphathelene kubalulekile, njengoba imiphumela ingase ibe mibi kakhulu, kungakhathaliseki ukuthi hlobo alula, hit umzimba, kwaze kwaba sekufeni.

Yonke imithi antiprotozoal ezihlukaniswe etukwe causative ejenti ethile isifo:

• umalaleveva,
• protivoamebnye;
• lisetshenziswe giardiasis;
• trichomoniasis;
• ngesikhathi leishmaniasis;
• I-toxoplasmosis.

Ngaphakathi zokwehlukanisa amaqembu noma indawo kanye mode of action ku izimuncagazi (njengoba kwenzeka protivoamebnymi kusho), noma ukuthonya ukuthuthukiswa ukuma elula (njengoba kwaba njalo endabeni ka-izidakamizwa olwa nomalaleveva). Cabangela lokhu njengesibonelo kohlobo oluthile kwamagciwane.

Njengoba izimali zihlukaniswe protivoamebnye

Izimo zethu zihluke kakhulu ezivamile amoeba ukutheleleka. Kwezokwelapha, lokhu zokugula kuchazwa njenganoma amoebiasis. Sibangelwa lenyama Entamoeba histolytica, okuyinto axazulule emathunjini ezinkulu, okuholela ekugcineni ukuvela izimpawu efana uhudo virus. Isiguli uyazwelana nathi ebuhlungwini esiswini, imfiva, wayekade esihlalweni ecasukile.

Ingxenye amoebae kungakuzuzisa parasitize odongeni emathunjini, noma kuphazamise isibindi. Sekube amacala isingeniso zabo ezingena emaphashini futhi ebuchosheni, lapho kubangele ukubukeka abscesses.

Yini protivoprotozoynoe ikhambi amebiasis, ungakwazi ukutshela konje bahlukene, kuye ngokuthi indawo amoebiasis Amagciwane. Ngakho, phakathi kwabo kukhona:

• izidakamizwa ukuthi isinyathelo amoebae ukuhlala mafutha anciphisa isikhala esingaphakathi emathunjini ( "Hiniofon", "Meksaform", "Enetroseptol" et al.);
• izidakamizwa ayisukumele amoeba ogangeni wamathumbu (kuleli cala, antibiotic nokwephulwa umthetho ngaphansi kwe nemibandela ukhona amoeba, - "tetracycline" noma "Oxytetracycline");
• izidakamizwa esebenza esibindini ( "Hingamin" "Chloroquine");
• ejenti esebenza ngasiphi amoebae indawo (nitroimidazole nemikhiqizo - "metronidazole", "Ornidazole" noma "Nirdazol").

ejenti Antiprotozoal: Ukwahlukaniswa umalaleveva

Ukuze umalaleveva zihlanganisa leqembu lezifo zako nge izimpawu ezifanayo: imfiva, imfiva, ubuhlungu bamalunga, ubende lakhulisiwe futhi isibindi, kanye-hemoglobin kwehliswa igazi. Ngalokhu ukutheleleka kubangela izinhlobo ezahlukene plasmodium ngokusebenzisa umiyane nabesifazane okuqondene uhlobo lwe Anopheles.

Njengoba sekushiwo, antimalarials abahlukene kuye umthelela ekuthuthukiseni Plasmodium. Kunamaqembu ezine zezitsha:

• gematoshizotropnye - ezithinta abomvu ukuma plasmodium ( "quinine" izidakamizwa "Hingamin", "hloridin", "Maloprim" noma "Pyrimethamine");
• gistoshizotropnye ezithinta ifomu kwangaphambi erythrocytic (izidakamizwa "Proguanil") futhi ifomu paraeritrotsitarnuyu ( "Primaquine" ukulungiselela);
• gamantotropnye kusho kunikela ngalokutsite gamantotsidny ( "Primaquine") kanye nomphumela gamantostatichesky ( "Pyrimethamine");
• inhlanganisela yemithi ( "Fansidar", "Metakelfin").

Main isinyathelo esifanayo, zonke zazo ejenti antiprotozoal - umonakalo lo okusithiyayo (retardation) inqubo yokuthola izinhlelo zamagama of acid nucleic kule elula, kanye ukubhujiswa ulwelwesi yabo cytoplasmic okwagcina kuholela kokufa nezilwanyana ezincane.

Ukwelashelwa trichomoniasis

Ngakho lapho esebenza khona, isibonelo, kanye nokulungiselela "metronidazole" lalisetshenziswa njengezaba ejenti main ekwelapheni trichomoniasis.

Ukutheleleka nge Trichomonas (Trichomonas vaginalis) kubonakala ohlelweni womuntu urogenital, okubangela urethritis ezingabantu, futhi lezinkinobho kwabesifazane. Njengomthetho, ezimweni ukutheleleka esolwa iphathwa efana kokubili abangaki azibandakanya nabo kwezocansi, ngisho noma ngabe isifo ungomunye wabo asymptomatic.

Ngo abesifazane, ukutheleleka, owenzeka ngo-sangasese, lesi sifo kubonakala ukukhululwa esiningi Foam mhlophe. Avame ube nephunga kabi kungaba umbala aphuzi noma ogqamile. Ngokuvamile uma lokhu kwenzeka futhi ubuhlungu ngesikhathi kocansi.

Kodwa lapho isifo urethra kokuba amajaqamba kanye ukuncinza ngesikhathi ukuchama ukuthi eyobonisa ukuthuthukiswa urethritis. Kule ngxenye ukulunywa futhi ububomvu e sangasese, kanye ukuvuvukala ngemomozi yakho.

Njengoba sekushiwo, lapho i-ejenti lomcoka zabesifazane protivoprotozoynoe futhi Urology - a "metronidazole". Kodwa ngenxa yokuthi bathi kule minyaka yamuva ukwanda isibalo namagciwane amelana kule izidakamizwa ekwelapheni izifo ngokusebenzisa izindlela ezifana "Tinidazole" noma "Ornidazole".

Okukushoyo ekwelapheni toxoplasmosis

Toxoplasmosis - esinye isifo, ekwelapheni lapho protivoprotozoynoe kusho esetshenziswa. Ukuthi lokhu ukutheleleka kwenzeka ukusetshenziswa inyama ehlaza noma kabi okugazingiwe, cishe, ngoba noma ubani akuyona imfihlo. lesi sifo siba ifomu ezingamahlalakhona ngokuvamile kakhulu, futhi ubonisa zihlukene kuye ngokuthi yiziphi izitho iyathinteka Toxoplasma (Toxoplazma gondii).

Ngo abantu buthaka omzimba, lo ukutheleleka livela, ngokuvamile izilonda emathunjini, iphaphu, isimiso se-lymph nesimiso sezinzwa, ngesimo encephalitis, lymphadenopathy generalized, noma myositis. Futhi lapho itheleleke abesifazane abakhulelwe toxoplasmosis kungenzeka imbangela sengozini e ingane, kanye wazalwa kungakabi isikhathi noma isisu.

Umuthi main ekwelapheni lesi zokugula wenza "hloridin" ngokuhlanganyela amalungiselelo sulfanilamide ( "Sulfadimezin", "Sulfadimetoksin" noma "Sulfapiridazin").

Izidakamizwa ukwelashwa giardiasis

Akunakwenzeka ukuba ukhumbule, echaza protivoprotozoynoe kusho ukuthi liphinde kwezidakamizwa ephatha ukutheleleka nge Giardia. Giardiasis - a zokugula evame kakhulu okubangelwa isibindi kanye nezinambuzane emathunjini. Ingozi yalesi sifo itholakala lokuthi ukuthi alikwazi ukuboniswa, kodwa abathwali Giardia ngaleyo ndlela ukuthelela abanye.

Acute e sifo izingane kanye nabantu buthaka omzimba. Ngokuvamile, isiguli ngaleyo ndlela waphawula sohudo syndrome, imfiva, ukuhlanza, ukuqubuka (isimungumungwane-like), ukudla, ukukhulisa kwesibindi, ukungakuthandi ukudla, futhi ubuhlungu obuhlabayo esiswini.

ejenti Ngempumelelo ekwelapheni giardiasis kukhona "metronidazole", "Ornidazole", "Akrikhin" futhi "furazolidone" lihambisana antihistamine kanye enterosorbents.

Yiziphi ezinye izindlela ezisetshenziswa njengeziwusizo antiprotozoal

Izidakamizwa asetshenziswa ukwelapha izifo ebhalwe ngenhla ngokusekelwe eBhayibhelini ngokuvamile aba elwa namagciwane kanye orientation. Ngakho, "metronidazole" iphilisi - leli thuluzi elwa namagciwane futhi protivoprotozoynoe ezingaba nomthelela ekuthuthukiseni Giardia, trichomonads futhi amoebae, kanti ezinye izilokazane ezincane anaerobic: peptokokki, streptococci, Bacteroides, Clostridium, fuzobakterii etc ...

Lesi senzo ivumela le izidakamizwa ukuze sibe abafundisi abaphumelela ngokumelene Trichomonas lezinkinobho futhi urethritis kanye giardiasis futhi uhudo amoebic. zibe nesiteleka esisemthethweni esihambisana Ezihlobene possesses izidakamizwa "Tiberal" ( "Ornidazole").

A nomuthi "delagil", ehlanganisa chloroquine phosphate, wabonisa ukuze isetshenziswe umalaleveva, amebiasis, kanye samathambo futhi omzimba izicubu erythematosus.

Kusho, esetshenziselwa leishmaniasis

Leishmaniasis - kungenye isimo sokugembula okuyiwona ukwelashwa liyadingeka izindlela protivoprotozoynoe. Lokho-ke lesi sifo futhi kwenzeka kanjani, ixhomeke amasosha omzimba isiguli kanye isayithi isilonda. Leishmaniasis sehlukaniswe mucocutaneous, cutaneous ehlasela umzimba kanye visceral. Lesi sakamuva kuthinta ubende kanye kwesibindi, futhi ujikeleza amagciwane egazini.

Ukuze ukwelashwa ezimweni ezinzima isicelo ngomjovo emthanjeni noma esicutshini izidakamizwa pentavalent antimony. Lapho izinhlobo isikhumba inikezwe ukutheleleka kwabo kwezinye izimo esikhundleni izidakamizwa "metronidazole" noma "Paromomycin."

Nakulokhu futhi, lokho kusho izindlela protivoprotozoynoe

Kusukela zonke lezi zindlela osekukhulunywe kuyacaca ukuthi ejenti antiprotozoal ukusiza wokuqeda umzimba amagciwane, protozoan emelelwa. Izidakamizwa oshiwo ngenhla senze ngokuvumelana nayo, zikhala inqubo ukuthuthukiswa kanye umjikelezo wokuphila.

Kodwa ukwelashwa protivoprotozoynymi izidakamizwa inemiphumela eminingi engemihle, futhi kunzima ngempela ukudlula. Ngakho, sitholakele khona ukutheleleka yisinanakazana esikhathini ekuqaleni - iphuzu elibaluleke kakhulu esikhathini yokwelapha lezi zifo. izifo Bakhulile abakwazi kuphela kudlule efomini okungamahlalakhona, kodwa futhi kuholele ukukhubazeka noma ukufa.

Kubalulekile kakhulu, azi khona isifo, kusenesikhathi ukubona onguchwepheshe, kodwa kulokhu, inqubo yokwelapha lizokwenza esiphezulu futhi alondoloze impilo. Musa sigule!