"Kalchek": yokusetshenziswa, analogs, ukubuyekezwa

Okufanele ukwazi ngaphambi kokusebenzisa lolu izidakamizwa eziyingozi, njengezinto "Kalchek"? Iziyalezo ukusetshenziswa wathi izidakamizwa Ukufundwa edingekayo. Kuyo uzothola izimpawu kanye contraindications ukusetshenziswa kwalesi izidakamizwa, kanye uthole ukuthi uma they fanele phi analogue nama-side effects.

Ifomu sokulungiselela, ukwakheka kanye nokupakisha

Ingabe uyazi ukuthi ifomu lapho ungakwazi ukuthenga izidakamizwa "Kalchek"? Yokusetshenziswa usitshela ukuthi izidakamizwa itholakala kuphela ifomu tablet. Ukwakheka nomuthi kuhlanganisa isithako esebenzayo ezifana amlodipine besylate (5, 2.5 no-10 mg). Ngokuphathelene izinto ezengeziwe, bese bahlanganisa dibasic calcium phosphate, corn isitashi, sodium isitashi glycolate, talc aziphothula, Silica colloidal kanye magnesium stearate.

Izibhebhe kukhona ibhamuza (10 nama-PC.), Yikuphi ezibekwe ebhokisini elenziwe amakhadibhodi.

I izakhiwo kwemithi sedivayisi yezokwelapha

Kanjani imithi "Kalchek"? Iziyalezo yokusetshenziswa uthi isidakamizwa kuyinto abakhethayo-calcium channel blocker, abafunda ekilasini le 2nd. Anakho antianginal, antihypertensive, vasodilating, nemiphumela antispasmodic. izinto Imithi kufakwe ukubunjwa le-ejenti, uyakwazi kuvimbele kugeleta calcium ion ku semithambo bushelelezi imisipha amaseli.

izakhiwo Anti-abanomfutho wegazi ophakeme zomuthi ngenxa nomphumela walo oqondile okuphumuzayo ku semithambo imisipha abushelelezi. Ngokuphathelene umphumela anti-anginal, le nomuthi okukhulunywa uyakwazi ukwandisa arteriole (neuropathy). Ngemva kwalokho, le kuholela ukwehla neuropathy ukumelana semithambo, okuyinto ke kuholela ukwehla ziphoqa esivimba amanzi O ₂ (i-oksijini).

Nokho, kufanele kuphawulwe ukuthi ngezinye izikhathi isenzo lokhu kusho umoya-mpilo, kunalokho, anda. Lokhu kungenxa ukunwetshwa nemithambo yegazi yenhliziyo (isb, angina vasospastic).

Kufanele kuqashelwe ukuthi i-tablet "Kalchek" akukho nemiphumela emibi Ukwakheka lipid kwegazi. They possess umsebenzi antithrombotic futhi antiatherosclerotic, ukwandisa izinga filtration (glomerular), kanye nethonya eliphuphile natriuretic.

Ngo sikashukela nephropathy izidakamizwa ayikwazi okwandisa microalbuminuria.

I izakhiwo pharmacokinetic zomuthi

Lapho ukumuncwa lesi sidakamizwa "Kalchek"? ochwepheshe lezivakashi zisikisela ukuthi ukumuncwa zomuthi lisuselwa ipheshana wokugaya ukudla (90%). okuhlushwa sakhe esikhulu kunazo zonke e-igazi ngemuva kwamahora 7-12. I bioavailability zomuthi imayelana 63-65%.

I asebenzayo izidakamizwa izidakamizwa lingena kusivimbeli gazi ebuchosheni futhi excreted nge ubisi lwebele. Amlodipine biotransformed esibindini (metabolites ngasebenzi akhiwa).

Esikhathini okukhipha ingashintshiwe engaphansi kuka-10% ekwakhiweni. Ngokuphathelene metabolites ngasebenzi, zibekwa isamba 60% emchamweni, futhi mayelana 20-25% ngo emathunjini bese kanye Bile.

izinkomba

Ngayiphi izifo a amaphilisi nesineke "Kalchek" angabelwa? Yokusetshenziswa (efana ithuluzi eboniswe ngezansi) inikeza ulwazi izinkomba ezilandelayo:

• angina esitebeleni;
• angina engazinzile;
• unomfutho wegazi ophakeme (lisetshenziswa njengedivaysi monotherapy noma ukwelashwa nge-ACE inhibitor, isisu thiazide, beta noma-alpha blocker);
• angina angiospastic (noma okuthiwa Prinzmetal angina).

Izimo

Ephambi kwezinduna iyiphi ngezimo zesiguli akufanele namaphilisi "Kalchek"? Yokusetshenziswa iqukethe Izimo ezilandelayo:

• hypotension lwemithambo;
• Hypersensitivity main asebenzayo izidakamizwa imithi.

Kufanele kuqashelwe ukuthi le izidakamizwa ayikwazi ukusetshenziswa ngoba iziguli abanokuhlangenwe hypersensitivity kuya dihydropyridine nemikhiqizo.

Izidakamizwa "Kalchek": yokusetshenziswa

Tablets "Kalchek" angina kanye nomfutho wegazi ophezulu iphathwa ngezilinganiso 5 mg ngosuku. Uma kudingekile, zingandiswa-10 mg.

Iziguli okwatholakala zenhliziyo osuke usuvulekile, impatho isiqalisile nge imithamo 2.5 mg ngosuku. Uma izidakamizwa kwamukeleka kahle ngokwezinga elithile, kungenzeka ukuthi kancane kancane ukwandisa umthamo (esingeqile 10 mg ngelanga).

Ngo isicelo amaphilisi njengengxenye ukwelashwa nge-beta-blocker, isisu thiazide noma ACE inhibitor ukulungiswa we lwemithi nokushintsha kokudla nokufakwa liyadingeka.

Izimpawu ukweqisa izidakamizwa kanye nokwelashwa inqubo

Yiziphi izimpawu ukweqisa izidakamizwa zenzeka lapho umthamo okungalungile imithi "Kalchek"? Analogue kanye izidakamizwa ngokwayo kungabangela evelele hypotension. Njengoba ukwelashwa isiguli kufanele anikezwe evundlile, futhi kancane phakamisa imilenze yakhe. Ngaphezu kwalokho, isidingo sokusekela umsebenzi izitsha inhliziyo negazi, ukuqapha izinkomba umsebenzi yamaphaphu kohlelo, kokulawulwa diuresis and Bcc.

Ukubuyisela semithambo ithoni nesineke unikezwa imithi vasoconstrictor. Ukuqeda imithelela-calcium channel ukuvinjelwa, isiguli iqondiswa (i.v.) calcium gluconate.

izidakamizwa ekuhlanganyeleni

amaphilisi kanye kanye "Kalchek" futhi "Warfarin" isidakamizwa akakubangeli izinguquko eziphawulekayo prothrombin isikhathi abameleli enempilo wobulili namandla.

Uma usebenzisa kokubili nomuthi kubhekwe futhi imithi "Digoxin" Akukabikwa ushintsho emakamu igazi yokugcina, futhi imvume yayo kwezinso.

ekuphathweni esisodwa izidakamizwa "Kalchek" futhi "Cimetidine" akunamthelela sezindawo pharmacokinetic ka amlodipine.

Nokukhulelwa kanye lactation

Kungakhathaliseki kungenzeka ngesikhathi lactation futhi sokukhulelwa ukuziphatha reception "Kalchek" amaphilisi? Yokusetshenziswa, odokotela yangempela wazise ukuthi nephephe yalesi izidakamizwa ngesikhathi sokukhulelwa futhi ukuncelisa ingane yakho ayisethiwe.

imiphumela emibi izidakamizwa

Iziphi izinkinga zokwelashwa kungabangela amaphilisi "Kalchek"? Iziyalezo uyalisebenzisa yini leli thuluzi kuqinisekisa ukuthi ukuqokwa kwakhe bangase baxabane engadingeki emzimbeni. ikakhulukazi abavamile phakathi kwabo kukhona lokhu okulandelayo:

• Izikebhe inhliziyo, iphika, palpitations, futhi ukufikelwa ukushisa.
• Isimiso sezinzwa (neuropathy central): imizwa yethu ishintshashintsha, isiyezi, imisipha amajaqamba, ikhanda, angaboni kahle, ukozela, asthenia, ukukhathala, paresthesia futhi myalgia.
• ipheshana wokugaya ukudla: Ubuhlungu obukhulu besisu, dyspepsia, jaundice cholestatic, isicanucanu, ukwanda transaminases (isibindi).
• Skin: erythema multiforme, pruritus, ukuqubuka.
• Okunye: Hyperplasia gingival, gynecomastia, imvamisa anda ukuchama, ubuthakathaka nokuvuvukala.

imiyalelo ezikhethekile ethola izidakamizwa

Hlobo luni ezicashile kubhekwe izidakamizwa kufanele babe nolwazi ngaphambi kokuba aqhubeke ephethe izibhebhe "Kalchek"? ochwepheshe lezivakashi bathi lokhu imithi kumele kusetshenziswe ngokuqapha okukhulu kubantu nge kahle isibindi umsebenzi, kanye senhliziyo (ezingamahlalakhona) kanye stenosis yomthambo i-aorta.

reception ngesikhathi esisodwa imithi "Kalchek" nabenzeli non-steroidal, nitrate, imithi elwa namagciwane kanye imithi hypoglycemic (TEMLOMO) kungenzeka.

Okuhlangenwe nakho kwabangane ukusetshenziswa emitholampilo ye izidakamizwa ezinganeni ezincane sishoda.

Tablets "Kalchek" azinamphumela ekhonweni lesiguli ukushayela imoto.

Imigomo nemibandela isitoreji izidakamizwa

Ukulungiselela "Kalchek" (5, 10 no-2.5 mg) kufanele agcinwe endaweni epholile, eyomile nemnyama aphume kufinyelela khona izingane ezincane. Impilo eshalofini izibhebhe kuyinto 2 iminyaka.

Izibuyekezo komkhiqizo okwelapha, futhi izindleko analogue yayo

Yini esikhundleni ithuluzi ezifana "Kalchek"? Analogs yalesi izidakamizwa ayatholakala cishe zonke drugstores. Phakathi ejenti ezivamile zihlanganisa ukuthaka imithi ngendlela elandelayo: "Agen", "Tenoks" "adipic", "Stamlo", "Akridipin", "Omelar Cardio", "Amlo", "normodipin" "Amlodipine" "Norvasc" "Amlovas", "Amlorus", "Norvadin", "Amlodigamma", "Cordy Kor", "Amlodhi", "Korvadil", "Amlodifarm", "Karmagip", "Amlokard-Sanovel", "cardilopin", "Amlong" "Vero Amlodipine", "Amlotop", "Amlonorm".

Kuyini izindleko izimali? Intengo isilinganiso umuthi 175-190 ruble Russian (5 mg, amaphilisi 30).

Ngokuphathelene amazwana iziguli, zingabantu esihle esikhathini esiningi. Ngokusho labo abake isicelo umshanguzo, ngempumelelo elwisana ne angina kanye nomfutho wegazi ophezulu. Kufanele kuphawulwe ukuthi inani elikhulu iziguli ujabule futhi iqiniso lokuthi lokhu izidakamizwa kahle ikubekezelele kubo. Nakuba kwezinye izimo iphilisi "Kalchek" namanje abangele imiphumela emibi ezifana ubuhlungu bekhanda, ubuhlungu besisu, isiyezi, isicanucanu nokungezwani komzimba nezinto esikhumbeni.