Izidakamizwa "Molsidomine": yokusetshenziswa, intengo, analogs

Ngokuthi ukugula angina, esibonakala umuzwa kabi emizweni ezingemnandi ezenzeka emva sternum. Izazi zithi lokhu ubuhlungu ngokuzumayo kwenzeka ngaphansi kokucindezeleka emva kokudla noma umzimba. Ngokuvamile okuthunyelwa umhlathi ongezansi, entanyeni, esifundeni Undercut, ehlombe kwesokunxele futhi uyaqhubeka amahora. isimo esinjalo ubalekela ngokushesha emva ukumisa umsebenzi noma ukuthola amalungiselelo akhethekile.

Isikhathi esining impela ezigulini angina imithi "Molsidomine". Analogue esiqondiso, izinkomba kanye izakhiwo kuchazwe lapha ngezansi.

Ubujamo, emabhokisini Ukwakheka

I nomuthi "Molsidomine LF" is imakethwa njengoba amaphilisi orange noma pink ukuma flat kushaya situngeletane imiphetho beveled. Ziqukethe 2 noma 4 mg molsidomine. Ngaphezu kwalokho, ukwakheka izidakamizwa kuhlanganisa izingxenye asizayo (Povidone K-25, amazambane isitashi, sucrose, umbala ukudla, i-lactose, magnesium stearate).

Lesi sidakamizwa okuthengiswa ibhamuza amaphakethe, okuyinto ezibekwe amabhokisi.

Izici izidakamizwa

imithi Okubukwe anjengokuthi vasodilator, izidakamizwa ie dilates imithambo yegazi. Emva kokuthola enciphile yayo ukubuya emithambo yegazi ukuze imisipha yenhliziyo nemithambo ithoni ama-venule. Lokhu kusiza ukuphungula ingcindezi ku Umthambo yamaphaphu futhi ukucindezeleka esivimba amanzi.

Umgomo we operation

kanjani "Molsidomine" ithebhulethi? Yokusetshenziswa uthi umphumela izidakamizwa ngenxa isenzo asebenzayo metabolite imfuyo yayo - linsidomina. Lo msuka kuthinta semithambo imisipha abushelelezi, ukunciphisa ithoni yabo. Ngaphezu kwalokho, liveza izindawo antiplatelet.

Uma bushelelezi imisipha ithoni kuyehla, nekwandzisa umtsamo embhedeni semithambo kanye nokucindezela incipha e ventricles inhliziyo. Ngenxa yalokho yethonya umthwalo inhliziyo futhi isidingo yayo ngoba i-oksijini liyancipha.

Asinakusho ukuthi ngaphansi isenzo molsidomine encishisiwe zibe we nemithambo yegazi yenhliziyo namagatsha awo ukunweba. Ngakho, kakhulu ngcono igazi ligeleze inhliziyo.

I kinetics zomuthi

Nomuthi "Molsidomine", intengo oboniswe ngezansi, is ugxile ipheshana yesisu ngama-90%. bioavailability Its 65%, futhi% 11 kuphela eboshiwe plasma amaprotheni.

Effect Its iqala ukubonisa izidakamizwa ngemva kwemizuzu engu-20 futhi kuthathe amahora mayelana 6. Ngemva kwenye imizuzu 30-50, lokuhlushwa izidakamizwa egazini ifinyelela esiphezulu.

Tablets "Molsidomine", yokusetshenziswa elibuye iqukethe, aguqulwe kwesibindi. Lokhu kwenzeka ngo-enzyme. Main izidakamizwa izidakamizwa is ibe sydnonimine 1, okuyinto kamuva siguqulelwa linsidomin. Kuyinto lokhu metabolite ukunikeza isinyathelo izidakamizwa.

Okubukwe izidakamizwa excreted ku umchamo phakathi nengxenye emahoreni amabili.

ubufakazi

"Molsidomine" Tablets akhonjiswa yokwamukela kulezi zimo ezilandelayo:

• nokuvinjelwa ukuhlaselwa angina;
• Ukwelashwa izifo cardiopulmonary;
• nokuqedwa angina kakade athuthukile.

Enqabelo ukuthola

Kubhekwe umuthi akufanele kuthathwe kanye pathologies ezilandelayo nezimo:

• hypotension ezinzima;
• lactation;
• ukufiphala;
• ukhulelwe;
• isilethikusebenza (isigaba acute), ikakhulukazi umfutho ophansi wegazi;
• ukushaqeka cardiogenic;
• umzimba carbohydrate.

Ukusebenzisa izidakamizwa e-acute isilethikusebenza kuvunyelwe kuphela ukuqapha njalo ngudokotela.

Tablets "Molsidomine": yokusetshenziswa

Isikali nokusebenzisa leli thuluzi incike ebufakazini obutholakalayo.

Ukuze kuvikelwe sokuhlaselwa ka angina imithi enqunyiwe 4-12 mg ngosuku. It is ezithathwe umlomo emva kokudla.

Uma usebenzisa izidakamizwa ngezinjongo zokwelapha iqondiswa 1-2 mg nsuku zonke 4-6 Ukweqiwa. Uma wayefisa, umthamo senyuselwa 2.4 mg. Isibalo amasu ukunciphisa izikhathi 2-3 ngosuku.

Ukuqeda kakade athuthukile angina iphilisi kufanele ufakwe ngaphansi kolimi.

side effects

Okumele kuqashelwe ngenkathi ngokuthatha izidakamizwa kokubuyekezwa, kumele uthobele yonke iziguli. Lokhu kungenxa yokuthi phakathi ukwelashwa abantu kungenzeka elandelayo imiphumela emibi:

• isicanucanu;
• ukwehlisa umfutho wegazi, ikakhulukazi ukwanda kokutheleleka kudlange;
• ikhanda, okuyinto ukuthuthukisa ekuqaleni ukwelashwa;
• ububomvu kwesikhumba;
• ukuqubuka (ivela kakhulu akuvamile).

izinyathelo zokuqapha

Ngaphansi kwezimo ezivamile, umphumela hypotensive zomuthi ibuthakathaka. Nokho, uma kuhlangene nezinye vasodilators noma ngesikhathi ekwelapheni abantu abane ivolumu esincishisiwe afundwa igazi noma hypotension kufanele uqaphele ikakhulukazi.

abantu abadala kanye kahle kwezinso noma isibindi umsebenzi linqume ngemithamo aphansi imithi edingekayo.

Izindleko esikhundleni kanye izindlela

Manje uyazi indlela yokusebenzisa "Molsidomine" amaphilisi-mbumbulu. Yokusetshenziswa zomuthi seyenziwe ngenhla.

Izindleko zalesi imithi ruble 90-100 iphakethe ngalinye. Uma kudingeka, kungase kuthathelwe indawo nezinye izidakamizwa ezifana "Dilasidom" noma "Sydnopharm".

Izibuyekezo umthengi

Kukhona Izibuyekezo eziningi mayelana Molsidomine amaphilisi ' ". Ngo iningi la abathengi izimangalo ukuthi ukulungiselela ngesikhathi esifushane kudambisa kobukhulu ukubonakaliswa basemtholampilo angina pectoris futhi senhliziyo. Futhi, iziguli eziningi ejabulisa eziphansi yalesi izidakamizwa futhi itholakala zonke Pharmacy. On the sinazo ngaphandle ukuthi ukusabela okungekuhle, kodwa Kungashiwo okufanayo kwemithi kakhulu.