Ithuluzi elithi "Roxer". Imiyalo yokusetshenziswa

Isidakamizwa esithi "Roxer" sinqunyelwe i-hypercholesterolemia eyinhloko (uhlobo lwe-2a, kufaka phakathi uhlobo lwe-heterozygous yomndeni), i-hypercholesterolemia (2b) ehlanganisiwe njengokwengeza ekudleni uma kungenakwanela ukusebenza kokwelapha kusuka eminye imiphumela engeyona imithi (ukulahlekelwa kwesisindo, ukuvivinya umzimba). Isidakamizwa sisetshenziselwa ngokuhlanganyela ne-cholesterol yokunciphisa ukudla.

Ithuluzi elithi "Roxer". Imiyalo yokusetshenziswa. Pharmacokinetics

Ukutholakala kwezidakamizwa yi-20%. Lapho bedla, ukumunca kunciphisa. Umuthi ungena emkhawulweni we-placental. Ukuqoqa kwenzeka endaweni yesibindi. I-metabolized cishe amaphesenti ayishumi omthamo.

Imithi "Roxer". Imiyalo yokusetshenziswa. Ukungafani

Ungabeki umuthi we-pathologies yesibindi esiteshini esisebenzayo (kubandakanya nokwandisa ukusebenza kwe-transaminases noma ukwandisa izinga lawo izikhathi ezingaphezu kwesithathu uma kuqhathaniswa nomngcele ophezulu wendabuko). Ukuqhathaniswa okubandakanya ukungasebenzi komuthi okwehlukile, ukukhulelwa, ukusabalalisa, isikhathi sokukhwabanisa. Imithi ye-"Roxer" ayinconywa ukuba isetshenziswe ngokulawulwa ngesikhathi esisodwa kwe-cyclosporine. Ungalali imithi yabesifazane ngesikhathi sabo sokuzala, abangasebenzisi izisu zokubeletha ezanele. Ikhambi alikhuthazwa kuze kube yiminyaka eyisishiyagalombili.

Umuthi we "Roxer". Imiyalo yokusetshenziswa. Imiphumela emibi

Le mithi ihoxisa i-paresthesia, neuralgia, ukulala. Ngesisekelo sokwelashwa, isiyezi, isicashu, ukuqothulwa, i- asthenic syndrome, kungase kwenzeke ukukhathazeka. Izimpawu ezimbi zihlanganisa i-dyspepsia, ubuhlungu besisu, i- pharyngitis. Imithi ibangela pneumonia, dyspnea, bronchitis, ukukhwehlela, i-rhinitis, isifo sokuphefumula kwesifo sofuba. Ngesisekelo sokwelashwa, kune-vasodilation, ukwanda kwengcindezi yegazi, i-myalgia, i-palpitation, i-arthritis, i-arthralgia. Emiphumeleni emibi yokuthatha imithi "Roxer" yeziqondiso zokusetshenziswa zihlanganisa i- angioedema, ukuqhuma kwesikhumba, ukuhlakulela, ukutheleleka emgqeni wokuvuthwa, ukuhlukumeza esiswini esingaphansi. Ezimweni eziningi, ukukhwabanisa kwamapayipi (ama-shins, ama-ankle, imilenze nezandla), ubuhlungu be-back, hypertonicity, i- anemia, isifo sikashukela, isifo se-influenza, i-ecchymosis, i-absent periodontal.

Ithuluzi elithi "Roxer". Imiyalo yokusetshenziswa

Amathebulethi athathwa ngomlomo, angasetshenzisiwe, agwinya yonke. Ukungena kuvunyelwe kungakhathaliseki ukuthi kukuphi ukudla kunoma yisiphi isigamu sosuku. Isilinganiso sokuqala ngu-10 mg kanye ngosuku. Emiyalweni yongcweti, inani lemithi linganyuka libe ngu-20 mg ngemuva kwenyanga yokungena. Ukwandisa umthamo kuma-milligram angu-40 kuvunyelwe kuphela ngaphansi kokuqondiswa kukadokotela. Kulezi ziguli ezinezimo ezivelele ekutheni kwenzeke yini ukuzamazama, inani lokuqala lingu-5 mg.

Ithuluzi elithi "Roxer". Imiyalo. Intengo:

Izindleko zemithi i-ruble engaba ngu-400.

Ulwazi olungeziwe

Uma kwenzeka ngokweqile, kunyuke ekubonisweni okungalungile. Ukwelashwa okuyisimiso kunqunywe . I-Antidote ayikho. Ngokumelene nesimo sesifo sofuba, i-hemodialysis ayisebenzi.