Imithi Sulpiride. Imiyalo yokusetshenziswa

Imithi "i-Sulpirid", intengo yayo ehlukahlukene ngaphakathi kwe-ruble eyikhulu, ingokwesigaba se-neuroleptics ye-atypical yeqembu lama-benzoamide ashintshiwe. Isidakamizwa sinomphumela we-antipsychotic wohlobo olulinganiselayo, ngokuhambisana ne-thymoanaleptic (antidepressant) nomsebenzi ovuselelayo. Inqubo yethonya ihlotshaniswa nemiphumela ye-antidopaminergic. Izindleko ezincane zomuthi zingase zibekwe njengezinsizakalo zokwelashwa kwezifo ezingokwengqondo . Isidakamizwa esithi "Sulpirid" (imfundo yokusetshenziswa iqinisekisa lokhu) iphumelela ekuqedeni ukubonakaliswa kwengqondo okungalungile ngokusuka ngemuva kwesilonda se-peptic ezingxenyeni zegciwane lokugaya. Ngesisekelo se-syndrome eyathukuthela, ubukhulu bezinhlungu zomzimba wesisu buyinciphisa, isimo sesiguli seziguli sithuthuka. Ngezilinganiso eziphansi, imithi iphumelela ekutholeni isizungu, kungakhathaliseki ukuthi imuphi uhlobo. I-agent inomthelela omuhle ekukhiqizeni i-prolactin, inomphumela we-antiemetic ophakathi (ukucindezela isikhungo sokuhlanza). Ukuhlushwa okuphezulu kuphawulwe ingxenye eyodwa nengxenye kuya emahoreni amathathu emva kokuba umuthi ungena ngaphakathi. Ukutholakala kwezidakamizwa yi-27%. Ikhambi litholakala ebisi. I-metabolism cishe ayibonakali kulowo muthi, idutshulwe izinso ngendlela engaqinisekisiwe.

Isidakamizwa "Sulpiride". Imiyalo yokusetshenziswa. Ukuqokwa

Isidakamizwa siboniswa njenge-monotherapy noma sihambisana neminye imithi. Imithi inqunywe ukuba i-schizophrenia (i-acute futhi ingapheliyo), izimo eziyingozi kakhulu, imidwebo yemvelo ehlukile, ukuphazamiseka kohlobo lwe-neurotic. Izinkomba zihlanganisa ukuzondeka kwanoma imuphi umsuka (ngesisekelo se-vestibular neuritis, vertebro-basilar insufficiency, isifo sikaMeniere , i- otitis media, ezimweni emva kwe-CCT). Njengomsizi, lesi sidakamizwa sinconywa izilonda ezilonda ululative ngaphakathi kwe-duodenum noma esiswini, kanye nesifo sofuba esiswini.

Umumo wokudosa

Amathebulethi "i-Sulpiride" kunconywa ukuba aphuze engxenyeni yokuqala yosuku (amahora angaba ngu-16), njengoba isidakamizwa sisiza ukwandisa umsebenzi womzimba. Ngosuku olunqunywe okungenani kuka-1.6 g. Ngo-schizophrenia of uhlobo olungavamile noma oluyingozi, ingqondo elula kakhulu, inani lokuqala lemithi lisuka ku 600 kuya ku-1200 mg. Leli dozi lihlukaniswe ngamazinga amaningana usuku lonke. Njengokwelashwa kwesondlo, u-300-800 mg umisiwe. Lapho izimo ezicindezelayo zinconywa zisuka ku-150-200 kuya ku-600 mg izikhathi eziningana ngosuku. Lapho ugozi lunikezwa ama-milligram angu-150-200. Ezimweni ezinzima, inani lemithi likhuphukela ku-300-400 mg. Isikhathi semithi "Sulpiride" (imiyalelo yokusetshenziswa iqukethe ulwazi olunjalo) ayikho ngaphansi kwezinsuku eziyishumi nane. Nge -rapy yokwelapha ye-peptic ulcer kanye nesifo sofuba esiswini, 100-300 mg 1-2 izikhathi ezibekiwe ngosuku. Inani lemithi ye-Sulpirid (imfundiso esetshenziselwa ukuxwayisa ngalokhu) kufanele ilungiswe iziguli ezinezinkinga zesistimu yezintambo. Kulezi ziguli, ukunciphisa umthamo noma ukwanda kwezikhathi phakathi kwamanani kunconywa.