Igciwane lohlobo Epstein-Barr: ukuhlobana, Epidemiology, izici yomtholampilo, ukwelashwa

igciwane lohlobo Epstein-Barr igciwane (mononucleosis esithathelanayo) - i-acute ezithathelwanayo isifo ezibangelwa amagciwane. Libhekene imfiva, lymphadenopathy, izindlala zamanzi indandatho oropharynx, Banti syndrome.

Ukuhambisana nesikhathi

Found igciwane lohlobo nge Epstein-Barr igciwane ikakhulukazi ebuntwaneni futhi kube inkomba yokuthi ukuntula somzimba sokuzivikela. I-ejenti causative kuyinto igciwane herpes, okuyinto ebucayi kuya lymphoid. Kulapha kukhona kabusha igciwane. Kukholakala ukuthi le virus kungase kube nomthelela nomdlavuza womlomo, lymphoma Burkitt sika. ezithathelwanayo mononucleosis syndrome singenzeka namanye amanxusa, okuyinto ebucayi kuya lymphoid.

lwezifo

Ukutheleleka kwenzeka yisiguli noma umnikazi ukutheleleka womuntu phakathi sisondelene. Izingane Lesi sifo siphatha kakhulu abaneminyaka engu 2-7 esikhathini ebusika-entwasahlobo.

pathogenesis

igciwane lohlobo Epstein-Barr igciwane ozwelayo uhlelo lymph. Ngakho-ke esethula lwegciwane avame ngokusebenzisa lymph pharyngeal indandatho. Lesi simo esiyingqayizivele sibangelwa kungenxa okuvela ukuvuvukala kanye ububomvu ka lwamafinyila, acinene ukuphefumula nobunzima.

Ngokwethulwa igciwane kokugqashuka zibhebhetheka wonke umzimba ngokusebenzisa igazi-lymph. Ngesikhathi esifanayo kuthinta-lymph, ubende, isibindi, umnkantsha, ukuthuthukisa esisheshayo izinqubo hyperplastic uvelichvayutsya emizimbeni ivolumu.

Epstein-Barr virus ukutheleleka: Izimpawu

Emva kwezinsuku 5-20 emva kokutheleleka liphuma ngokucijile 40 ° ^C lokushisa, yempilo engeyinhle, okwenza kwaba nzima acinene ukuphefumula, kukhona ubuhlungu emphinjeni. Intamo kuyinto ephawulekayo sikhubazekile ngenxa lakhulisiwe zamanzi. Ngesikhathi esifanayo okwandisa zonke izingxenye neuropathy visceral. Amalaka avuvukele zingavuvukalanga, nge patina elimhlophe-ephuzi noma ezingcolile-grey. Lokhu kuholela nobunzima ukuphefumula. Isikhumba livela ukuqubuka zahlukahlukene kakhulu ngaphandle kwasendaweni eqondile. Hepatosplenomegaly - into njalo. Kubonakala encane isikhumba aphuzi futhi sclera, izimpawu zokusha kwesibindi.

ukuhlola

Kucwaningo wegazi leukocytosis Kutholwe kumayunithi kwezigidi ezingu 20-30, anda ngenani monocytes, bilirubin yanda, ALT. Lapho igciwane PCR DNA ezitholakele igazi serum nge ekutholweni senani. Ngekhono okusezingeni eliphezulu usebenzisa haemagglutination, latex agglutination, ELISA, ukuze IgG futhi Igm.

Epstein-Barr virus ukutheleleka: ukwelashwa

Isicelo esikhathini acute interferon, acyclovir, tsikloferona unika imiphumela sobuntu sokuhlalisana ngokuthula. Uma uxhuma secondary ubovu izifo kanye namafomu kabi isifo kungcono sebenzisa antibiotic (acyclovir) kanye ama: ngemithamo ngokulinganisela prednisolone. ampicillin Isicelo contraindicated ngoba eheha okuvela ukusabela sokuhlasela kwamasosha omzimba.

ukuba nombono ongafani ngeke

Ngo ezwe elaliyi-USSR igciwane lohlobo nge Epstein-Barr igciwane akakunikanga ukufa olulodwa. Kukhona amacala ukufa ngenxa yezinkinga: ukudabuka splenic, encephalitis, myocarditis. Ezimweni ezingavamile, kukhona chronicity ukutheleleka.