"Doxycycline" - lokho lawo amaphilisi? Yokusetshenziswa, ngempela

"Doxycycline" - okuthathwe kuso la amaphilisi? Ngokuqinisekile iziguli eziningi abamiswe ukuba wathi nomuthi, ukukhathazeka mayelana nalolu daba. Isikhathi esining impela, odokotela batusa ukuthatha imithi ethile, ngaphandle kokuchaza ukuthi ayasebenza nakhona, njengoba umthelela emzimbeni, uma uneminye contraindications engemihle. Ngenxa yalokho, ezinye iziguli azikwazi ngcono, kodwa kunalokho ukuwohloka.

Ngokuqondene nakho konke okungenhla ngaphambi kokuthatha izidakamizwa Kunconywa Qiniseka ukuhlola nge udokotela, ngayiphi injongo ke elanikelwa kuwe. Uma impendulo ecacile ungakazitholi, sincoma ngokucophelela uhlole imiyalelo afakiwe.

Ngakho, "Doxycycline". Kusukela ukuthi lezi amaphilisi uma uneminye Izimo? On mibuzo neminye ephathelene lo mkhiqizo, siyosabela esihlokweni ethulwa.

Ukwakheka, umumo, futhi ekufakeni lo nomuthi incazelo

Ngaphambi kokuba siphendule lo mbuzo, "" Doxycycline "- okuthathwe kuso la amaphilisi," kufanele ukusho ukuthi ingxenye lokhu imithi.

Ukwakheka izidakamizwa ngaphansi ukucatshangelwa ingena isici okufana ayezosebenza njengabaqondisi doxycycline (ketshezi e imfundo umelwe doxycycline hiklata). Ngaphezu it, nomuthi yakhiwa futhi izithako elandelayo eyengeziwe: magnesium stearate, monohydrate lactose futhi amazambane isitashi.

I nomuthi "Doxycycline" is imakethwa ngesimo kanzima gelatin amaphilisi ukuthi babe ukuma cylindrical futhi ephuzi ngombala. Ngaphakathi ziqukethe powder aphuzi kokuba amabala amhlophe.

Kuvame emelelwa uhlobo amaphilisi izidakamizwa ebizwa. Lapho empeleni akuzona okunjalo.

Igobolondo capsule lokhu izindlela siqukethe propyl parahydroxybenzoate, glycerol, methyl parahydroxybenzoate, gelatin, izithasiselo E110 futhi E104, kanye sodium lauryl sulfate.

Ngo iphakheji sithengiswa "Doxycycline"? Amaphilisi ezibekwe Valium emaphaketheni planimetric, okuyinto equkethwe amakhadibhodi amabhokisi.

Asinakusho ukuthi lokhu izidakamizwa ikhiqizwa uhlobo umkhiqizo nqabela-omisiwe, esetshenziselwa ukulungiswa isixazululo ukumnika.

"Doxycycline" Isimiso yokusebenza zomuthi-antibiotic

Uyini izidakamizwa "Doxycycline"? Imiyalelo (intengo, ukubuyekezwa mayelana imithi banikwa ngezansi) Lithi kuyinto lulwimi zokwenziwa ejenti-antibiotic bohlanga kwamaphilisi - tetracyclines, ezithinta spectrum ngokwanele ezibanzi womsebenzi.

izidakamizwa Okubukwe uyakwazi kunethonya nomphumela bacteriostatic. It kuvimbela amaprotheni zamagama izinqubo microorganism elimazayo.

Ifinyelela inhliziyo ngaphakathi engqamuzaneni, isithako esebenzayo zomuthi ngokushesha mathonya e Amagciwane yabo. Hiklata Doxycycline kuvimbela synthesis amaprotheni atholakala emangqamuzaneni microbial, futhi unika zokuthutha aminoacyl-RNA.

Izici zomuthi

Maqondana nanoma yikuphi amagciwane, umuthi kwaphumelela kakhulu, "Doxycycline"? Action (elimazayo) zomuthi siqondiswe Gram-HIV nezilwanyana ezincane ezifana cocci aerobic, aerobic kanye anaerobic spore-ukwakha futhi amagciwane nonspore ukwakha kukhona aerobic.

Ngaphezu kwalokho, yokwamukela izimali abe nomthelela omubi impilo amagciwane Gram-negative, kokubili cocci aerobic namagciwane aerobic.

Ngikuphi okuhlukileko kuneGreyidini "tetracycline" antibiotic "Doxycycline"? Ochwepheshe bezifo, umuthi zakamuva ngezinga elincane kuvimbela microflora emathunjini. Ngaphezu kwalokho, ukumuncwa salo egcwele, kanye nomphumela oqabulayo - eside.

Akunakwenzeka ukuba uqaphele iqiniso esiyicabangelayo umsebenzi elwa namagciwane izidakamizwa lingaphezulu kakhulu kunezinye tetracycline zemvelo. Ukufundiswa uthi kusebenta zokwelapha zomuthi siboniswa yokwamukela ngisho kwafakwa isilinganiso esincane semithi izidakamizwa.

Amapharamitha Kinetic amaphilisi

It is amuncwa antibiotic "Doxycycline"? Absorption zomuthi e eliphezulu kakhulu futhi fast kakhulu (mayelana 100%). Kulokhu, ukusetshenziswa ukudla akuphazamisi degree of ukuncela.

Umuthi kuqhathaniswa kalula encibilikayo lipids. Nokho, it has ziyezwana ongaphakeme e yokubopha calcium ion.

Ngemva kokuthola lezi nomuthi e isamba 200 mg isikhathi ukufinyelela lokuhlushwa wobuningi egazini kwaba 2.5 amahora.

Ingqikithi asebenzayo kuyinto Lubophela-antibiotic ukuze plasma amaprotheni at 80-95%. Kuyinto kahle ku izicubu kanye izitho. Cishe imizuzu 45 ngemva ekuphathweni ngemlomo ngaloko lokusandza kwenteka zokwelapha izidakamizwa lokuhlala zitholiwe isibindi, ubende, izinso, wendlala, iphaphu, ithambo, iso kwezicubu, amazinyo, Bile, ascites, futhi uketshezi pleural, exudate lwamalunga, futhi gingival uketshezi crevicular, exudate engaphelele kanye sinuses maxillary.

Kumele kuqashelwe futhi ukuthi "Doxycycline" Bufinyelela kuhle ezimbi umgogodla intambo uketshezi.

Futhi ngaphansi ukucatshangelwa kunqunywa esebenzisa e ubisi lwebele futhi itholakala nge placenta.

Umzimba we-antibiotic esibindini (mayelana 30-55%). isigamu-ukuphila Its amahora 12-16.

Ngekusetjentiswa okuphindiwe imithi angase buthelela.

ukulungiselela ezibonisiwe ngokusebenzisa emathunjini nezinso. Ngo abantu ukusebenza kahle ka pheshana urinary excretion zomuthi ngokusebenzisa uketshezi gastro-emathunjini.

Izidakamizwa "Doxycycline": ukuthi lezi amaphilisi?

Izimpawu I-yokwamukela ithuluzi kukhona ezihlukahlukene. Izibhebhe zingafundwa kulezi zimo ezilandelayo:

• practice ENT izifo ka engenhla ipheshana zokuphefumula (namathansela, otitis, sinusitis, njll);
• Izifo ukuvuvukala futhi ezithathelwanayo, eyayibonakala ezibangelwa amagciwane ebucayi, kanye zokuphefumula ipheshana izifo (tracheitis, pharyngitis, inyumoniya, ukucinana kwemigudu yokuphefumula, esingelapheki noma oyingozi, wamaphaphu ithumba, lobar inyumoniya, empyema);
• e Gastroenterology izifo yaleli pheshana emathunjini bese ipheshana biliary (gastroenterocolitis, cholecystitis, isifo sohudo "ezihambini", uhudo bacillary, cholangitis);
• ezithambile kwezicubu isikhumba izifo (ukusha gciwane, phlegmon, imihuzuko, abscesses, isilonda, whitlow, njll ...);
• izifo ezithathelwanayo esweni, yaws, ugcunsula, yersiniosis, rickettsiosis, legionella, i-chlamydia kwasendaweni ezahlukene, proctitis, prostatitis, Q imfiva, typhus (kuhlanganise umkhaza, typhus futhi yansukuzonke), umkhuhlane nezimanakanaka, amoebic nesihudo bacillary, isifo saseLyme, actinomycosis, tularemia, ikholera, umalaleveva,
• e Urology izifo kohlelo urogenital (endometritis, cystitis, pyelonephritis, urethrocystitis, urethritis, endocervicitis, mycoplasmosis urogenital, orhiepididimit acute, prostatitis, isipatsholo);
• ngesikhathi exacerbation iziguli esingelapheki ukucinana kwemigudu yokuphefumula kuze iminyaka 65 njengoba izidakamizwa "kuqala" uchungechunge (ngaphandle izifo concomitant);
• e ukutheleleka bronchopulmonary (exacerbation) odabuka staphylococcal kubantu abanesifo sokuqaqamba kwamalunga chlamydial, cystic fibrosis futhi ehrlichiosis granulocytic;
• e prostatitis oyingozi futhi pheshana urinary ukutheleleka kwasebekhulile (kubangelwa Escherichia coli);
• therapy lihambisana leptospirosis, psittacosis, trachoma, psittacosis, ehrlichiosis granulocytic;
• therapy lihambisana brucellosis, pertussis, osteomyelitis, subacute endocarditis webhaktheriya, sepsis, peritonitis;
• nokuvimbela yezinkinga ukonakala nasezinkingeni ezilandela ngemva kokuhlinzwa, ngenkathi uhambela endaweni lapho ikakhulukazi zamagciwane luvame amelana chloroquine nomalaleveva.

Izimo nomuthi

Nomuthi "Doxycycline" ngesikhathi ureaplasma kusiza kahle. Nokho, ulisebenzise wobufakazi abakwazi njalo. Ngokusho imiyalelo, umuthi uvinjelwe ukusetshenziswa ku:

• ukuntula lactase;
• hypersensitivity kuya doxycycline, nezinye tetracyclines izinto nezidakamizwa;
• zokungezwani ne-lactose;
• porphyria;
• zikashukela-galactose malabsorption;
• leukopenia;
• ukungakhuli ezinzima hepatic;
• e abantwana kuze iminyaka eyishumi nambili;
• enesisindo esingaphansi 45 kg.

Nokushintsha kokudla nokufakwa umuthi olwa namagciwane abadala kanye nezingane

kufanele Ngithatha kanjani imithi "Doxycycline" (intengo ithebhulethi laloku lokubhalwe lapha ngentasi)? Amaphilisi umuntu ngemithi elwa namagciwane kumele kusetshenziswe emva kokudla. Kulesi ukulungiselela kufanele wageza phansi imali eyanele ketshezi efudumele.

Indlela okuchazwe izidakamizwa kakhulu kunciphisa amathuba yokucasuka ulwelwesi emphinjeni.

Umthamo Kunconywa udokotela, okufanele kuthathe isiguli ngaso sonke isikhathi kufanele ihlukaniswe 2 imithamo. Kuyinto efiselekayo ukusebenzisa capsule kanye amahora 12.

Izidakamizwa "Doxycycline": Isikali

Ngokuvamile, odokotela libeke ithuluzi at umthamo ezilandelayo: Ngosuku lokuqala - 200 mg, bese 100-200 mg (kuye ngokuthi isifo).

Uma isiguli sine-inqubo ezinzima ezithathelwanayo, kulo lonke yokwelapha kunconywa ukuba baphuze 200 mg zomuthi ngosuku.

Ngo uthi sokugembula, okuyinto zazibangelwa chlamydia, mycoplasma futhi ureaplasma, imithi elwa namagciwane yaphathwa Isikali ejwayelekile. Thatha le imithi, kuyinto efiselekayo izinsuku 11-15.

Kungenzeka yini ukuba sihlanganise nezinye amaphilisi "Doxycycline"? Ukuhambelana nale imithi nezinye izidakamizwa ungokoqobo impela. Njengomthetho, incike uhlobo lwesifo zangaleso busebenze. Uma kudingeka, kubhekwa ama-antibiotic kungenziwa kuhlangene "Clindamycin" futhi "Gentamycin."

Ezinye izindlela zokuphatha-antibiotic

Amaphilisi Abonayo "Doxycycline" yi-lunywa umkhaza kufanele athathwe kuphela iseluleko kadokotela. Kubalulekile kakhulu ukusebenzisa imithi njengoba isilinganiso izifo amahora kungakadluli 72 ngemva kokulunywa oqondile.

In izifo sibi ukuvuvukala kule abesifazane izidakamizwa ebekiwe ngesikhathi mg 100 kabili ngosuku. Abesilisa nabo Kunconywa ukuthatha ke noma umthamo ofanayo futhi imvamisa efanayo, noma umthamo 300 mg kanye.

Izinsana emva kokufinyelela eminyakeni ewu-8 izidakamizwa iqondiswa i inani 4 mg ngayinye 1 kg ngosuku lokuqala, bese 4.2 mg ngayinye 1 kg ngosuku (kuye ngokuthi isifo).

Ukuvimbela yezinkinga ezithathelwanayo angase avele lapho isisu, mg 100 zomuthi kumaminithi angu-60 ngaphambi inqubo 200 mg isigamu sehora ngemva.

Abantu ne ugcunsula yesibili futhi eyinhloko okufanele athathe 300 mg izidakamizwa ngosuku izinsuku ezingu-10.

Reception "Doxycycline" in iziguli isipatsholo kufanele kube 100 mg kabili ngosuku izinsuku 2-4. Amadoda urethritis gonorrheal Kunconywa umthamo owodwa we-mg 300. Uma lwegciwane nemithi, kungenzeka ukuthatha 200 mg zomuthi izinsuku 4 (kwabesifazane - izinsuku ezinhlanu).

Ephambi kwezinduna i induna-antibiotic kanye induna kumele kusetshenziswe at mg ngelanga 50. Kulokhu, isikhathi ukwelashwa kufanele kube amasonto 7-12.

Indlela esiphatha ngayo isifo saseLyme? "Doxycycline" nge uphethwe linqume esiqhubeka 3-5 izinsuku at 200 mg nsuku zonke.

ukusabela ezingezinhle

Ngo seziguli ezithola ejenti-antibiotic e isiguli esilandelayo izimo zokucabanga okubangelwa isifo kungenzeka:

• ukuthuthukiswa anorexia;
• ukuhlanza, waqinisa intracranial, ikhanda elibuhlungu, papilledema, kwehle esesuthi, isiyezi, imiphumela anobuthi on isimiso sezinzwa esiyinhloko;
• enkeneneza ezindlebeni;
• enterocolitis, isicanucanu, kolwelwesi, uhudo, esophagitis, ukuqunjelwa, dysphagia, ubuhlungu besisu, nesifo pseudomembranous, glossitis, ulceration ka ipheshana wokugaya ukudla;
• ukuqubuka maculopapular, ukushaqeka anaphylactic, pruritus, Stevens-Johnson syndrome, siwasebenzise kwesikhumba, izidakamizwa lupus erythematosus, angioedema, urticaria, ukusabela anaphylactoid, anaphylaxis, ukuqubuka erythematous, ukusabela anaphylactoid, dermatitis exfoliative ;
• diplopia ngenxa lenyuka ingcindezi intracranial, angaboni kahle, scotoma;
• ukwehlisa umfutho wegazi, pericarditis, erythema multiforme, tachycardia;
• ukwandisa izinkomba transaminases hepatic, isibindi kahle, cholestasis, isifo sokusha kwesibindi kohlobo sokuhlasela kwamasosha omzimba;
• anaemia hemolytic, neutropenia, thrombocytopenia, leukopenia, kwehle prothrombin Inkomba, eosinophilia;
• myalgia, arthralgia;
• photosensitivity, goiter, superinfection, ukuvuvukala endaweni anogenital, ushintsho ukondleka umbala wamazinyo, lezinkinobho, a syndrome efana serum ukugula, glossitis, ezinobuthi epidermal necrolysis, proctitis, stomatitis;
• ukwandisa ukusebenza asalile nitrogen urea.

Inani kanye efanayo amalungiselelo

Kungakanani buyisidakamizwa "Doxycycline"? amaphilisi Inani (izingcezu 10) kuncike eziseceleni ekhemisi amanethiwekhi. Njengomthetho, izindleko imithi enjalo ingeqi ruble 20-30.

Uma idinga ukushintshwa, odokotela batusa ukusetshenziswa kwalezi ejenti antibiotic "Doxycycline Verein", "JUnidoks Soljutab", "Dovitsil", "Doxycycline hydrochloride", "Doksilin", "Doxycycline Nycomed", "Doksipan", "Doxycycline-akos" .

Kufanele ngokushesha kuqashelwe ukuthi izindleko zonke lezi zimali kungaba ukucabangela elingaphezulu kakhulu kwaleli. Ngakho-ke, ngenxa yokuntuleka kwezinhlelo ezibanzi contraindications side effects, iziguli bakhetha ukusebenzisa "Doxycycline".

Amazwana mayelana imithi elwa namagciwane

Uphenyo "Doxycycline" ukulungiselela, akukho kakhulu. Labo zemibiko ezitholakalayo, kusale ikakhulukazi iziguli owasebenzisa izidakamizwa ekwelapheni i-chlamydia kanye nezifo ezithathelwanayo of eliphezulu ipheshana zokuphefumula futhi umgudu wokuphefumula. Ngokuyinhloko, akhayo. Lesi sidakamizwa siyasebenza ngempela kubonakala ukuba khona uthi okukhulunywa.

Kufanele kuphawulwe ukuthi ngokuvamile "doxycycline" ashiye okubuyayo, nalabo ezigulini eziye babesebenzisa lona ukuze induna kanye induna.

Asikwazi ukusho lokho, kodwa okubuyayo ku imiphumela yalesi izidakamizwa zitholakala futhi okuthunyelwe ezimbi. Njengomthetho, zihlotshaniswa ekuthuthukiseni inombolo enkulu yemiphumela emibi ku pheshana emathunjini.