Cushing Syndrome ezinjeni: Izimpawu kanye Ukwelashwa. Cushing Syndrome ezinjeni: kanjani ukuphila?

Endocrine uhlelo - lena enye yezinto eziyimpicabadala enkulu ilungu elithile lomzimba wethu. On the nezindlala endocrine iboshelwe cishe kuzo zonke izinqubo kwamakhemikhali emzimbeni, futhi ushintsho kancane kwamazinga ama-hormone ngokuvamile iholela imiphumela engelapheki. Uma sikhuluma emkhakheni wezilwane, ezivame kakhulu disorder ezinjalo, Cushing Syndrome. Ngo izinja, avame kungukuphula kwenzeka kwasebekhulile, futhi namuhla sihlaziya ngokuningiliziwe lokho nokuthi ukuze kulwiwe nakho. Lesi sihloko ulwazi kuphela, noma kunjalo, ukuze kuhlonzwe kanye nokwelashwa zemithi oluthandwa kudingeka ukuba aye kudokotela.

Kuyini Cushing Syndrome e izinja

Lokhu zokugula, etholakala akunjalo ezingavamile njengoba kungase oyifunayo. Ukwephulwa ukuthi pituitary isilwane uqala nenani eliphezulu kakhulu ukwaba cortisol. Lena i-hormone kubaluleke kakhulu, okuyinto ikhambi lemvelo enamandla yokulwisana ukucindezeleka. ngeke sihlale sicabanga lo mshini wezenzo kwale hormone emzimbeni, singaphetha bathi yalolu ketshezi ngeke wokunxusa bonke zigcine yokulwisana kwamathonya amabi imvelo.

Thanda, izinzuzo okuqinile, kungani echaza le nqubo ibingekho, ukhuluma ngani Cushing Syndrome e izinja? Iqiniso lokuthi labo amanani le-hormone, okuyinto isiqala wehluke igazi, ngokweqile ngisho indlovu. A pituitary indlala, okuyinto ukulawula inani hormone ekhiqizwa ngokuvamile bayakhishwa kusukela kule nqubo. Ngenxa yalokhu, isilwane sakho ubhekene nemiphumela ebuhlungu kakhulu.

imiphumela engemihle

Cushing Syndrome ezinjeni kuholela yokuthi ukuziphatha kwesilwane sishintsha. Njengoba kuthiwa okuthile engqondweni. Inja bahlushwe njalo, ukoma uyakhathaza. Lokhu kwakha load yakho iphezulu kakhulu izinso, futhi ngaphezu kwalokho, kuholela ukuchama ngokweqile. Lesi sifo kungaba yingozi kakhulu, futhi ngokushesha ngokwanele. Isizathu salokhu kalula wachaza ngokuya izitho zomzimba. Umzimba uyakwazi viva futhi ngokushesha ngaleyo ndlela bakhathale izikhathi eziningana. Zokunakekela izilwane kunezimo lapho isimo somzimba iminyaka emithathu inja, ogulayo nalesi sifo, ukuwohloka somzimba ezifanayo inja 13-15 iminyaka.

Izimpawu main

Manje ake sixoxe ngendlela ungakwazi usola Cushing Syndrome ezinjeni. Okokuqala abanikazi sinake isifiso yanda. Isilwane uqala ngokushesha wagqoka isisindo. Ngo parallel, ungabona ukoma esiqine kakhulu futhi ukuchama kaningi. Isilwane asikwazi eside kodwa wazibekezelela, futhi, naphezu ngokukhuphuka kwenani uhambo, namanje pissing ekhaya.

Empeleni, lesi sifo asivelanga ndawo, futhi kancane kancane kanye zimpawu igqanyiswe ngokwengeziwe. Inja uba ntekenteke futhi ucobekile, bayozela, kodwa ubonisa esesuthi esihle. Belly sags ngenxa ababuthakathaka imisipha besisu. Kukhona ukukhathala ngokushesha kakhulu. Kancane kancane engeza impandla. Izindawo ezinkulu eziseningizimu ye-wesikhumba hairless ngokuphelele. Ngokuvamile amasayithi emzimbeni, kodwa hhayi ekhanda noma izinyawo. Ukulunywa engekho. Uma ungatholi ukwelashwa, ngokushesha kakhulu ku ngemuva kwalesi sifo ukuthuthukisa sikashukela.

Izimbangela zesifo

Eqinisweni, bezilwane bayahlawumbisela eziningana ukuthi kungani izinja uhlushwa ukuphazamiseka kwama-hormone. Nokho, imbangela eyinhloko libizwa isimila, iziteleka adrenal. Ngokuvamile, odokotela esizama ukulungisa lesi simo ngosizo ukuhlinzwa noma imithi, okuyinto futhi inemiphumela yabo nemiphumela. Nokho, lesi akusona isizathu kuphela kungabangela Cushing Syndrome ezinjeni. Photo usikhombisa izinguquko zangaphandle ezenzeka nge izilwane ezigulayo, kodwa kamuva sizobe ubuyele izimpawu.

Esinye isizathu esingenza kube adenoma pituitary. Ngakho-ke, isidingo bacele ukuba ahlole futhi pituitary nezindlala adrenal. Nokho, ukuthola isimila, udokotela nje ekuqaleni umsebenzi walo. Kumele namanje ukunquma izilonda ingozi noma abulalayo, sibhekene, bese ukubikezela Inkambo yokwelashwa.

nezici ezithile

Kukhona izinhlobo ezithile, phakathi lapho sifo sivame kakhulu kunamanye. Ngakho, engozini terriers futhi okwakwenza abashayi-sibhakela zonke izinhlobo. Lokhu kungenzeka futhi ihlanganisa dachshunds, beagles, poodles futhi Dachshund. Ngokuvamile lesi sifo abadala singangena ngubani batholile engu-7-10. Ngalesi ubudala, odokotela bangathola ukuthi kuphela silondoloze isimo umzimba ngangokunokwenzeka. Nokho, futhi kwatholakala ukuthi nginesifo Cushing Syndrome, futhi kule nkathi sasivumela abasha - ezinjeni ezingaphansi kweminyaka engu-iminyaka emibili. Lesi sifo kuyingozi kakhulu ngoba ukwenza ngokushesha zonke izinhlaka futhi izinhlelo, futhi ngenxa yalokho, ngaphandle kokwelashwa, awokuthi ukufa sesilwane, kanye nokwehla sina sokuphila nge ukwelashwa okufanele.

inhlolovo

Kubaluleke kakhulu ukuba thembeke uqinisekise Cushing Syndrome ezinjeni. Sitholakele isifo luyindida kakhulu, hhayi yonke imitholampilo ukwazi ukunikeza izimo ezidingekile lokhu. Ngokuyinhloko udokotela kumele ahlole isilwane futhi ukuthatha ukuhlolwa ezidingekayo. Engokomfanekiso kuyinto ukuhlaziywa emitholampilo kwamakhemikhali egazi noma omchamo ukuhlaziywa, okuyinto ebaluleke ukuhlola izinga amaprotheni.

Ukuze sicacise lo dokotela isithombe angabeka-X ray, okuyinto ebonisa ukwenyuka kwezinga isibindi noma ezilamatshe aligugu adrenal. Kuyadingeka ukuba afeze ultrasound siqambe isimila we nezindlala adrenal. Imiphumela yaloku kuhlola okungenhla Proper akufanele kuphela ukuqinisekisa Cushing Syndrome ezinjeni. Izimpawu, imithi okuyinto ukuwethamela esigabeni esilandelayo zingase zibe ulwelwe, futhi ngenxa yalokho, kubaluleke kakhulu ukuthola umthombo wenkinga.

ukwelashwa

Lena isikhashana nzima futhi enesibopho. Kulesi sigaba, udokotela kufanele bakhethe ukwelashwa okufaneleka kakhulu kunokunye. Ukubuyisela amazinga cortisol, ukusekela umsebenzi zonke izinhlaka futhi izinhlelo - kuyinto umsebenzi oyinhloko obuqalene kuye selokhu kwatholakala Cushing Syndrome. Ngo izinja, ukwelashwa kungase kuthathe indawo ngezindlela ezimbili.

Indlela yokuqala - ukuhlinzwa. Ubonisa akuzona zonke izilwane, kodwa kuphela labo isimila we nezindlala adrenal. Endabeni pituitary adenoma kusenzima, kanye nezindlala adrenal nje zisuswe nokuphila yezilwane okukhulunywa ukwelashwa kwama-hormone.

Indlela yesibili - yezokwelapha. Kulokhu, nokwelapha hormone, kulesetayelekile amazinga cortisol. Lo mkhiqizo "Mitotane". Ethola ziqale umthamo mg 50 ngelanga ngalinye 1 kg isisindo. I umthamo wansuku zonke sehlukaniswe 2-3 Ukweqiwa. Treatment baqhubeka amasonto amabili. Isimo sesilwane kuyaqashwa nge ukuhlolwa kwegazi. Ngu ekunciphiseni emazinga cortisol egazini ukuze amagugu kuvunyelwe kudingeka ukuya Isikali izidakamizwa 50 mg / kg kanye ngesonto.

Eyesibili inketho, okuyinto evame udokotela - umuthi "Ketoconazole". Okokuqala wagunyaza lawo izilwane abanale Cushing Syndrome ngemuva namanje okhulayo kanye umonakalo isikhumba fungal. Ukuthatha izidakamizwa phakathi nesonto lokuqala - 10 mg ngayinye 1 kg esisindo (izinyathelo engaphezu kwemibili). Ngesonto lesibili umthamo luyanda 20 mg ngayinye isisindo 1 kg (Ngokuqondene izinyathelo ezimbili). Ekugcineni, ngesonto lesithathu yokwelapha ihilela umthamo wansuku zonke 30 mg ngayinye isisindo 1 kg.

Indlela ukunquma ukuphumelela ukwelashwa

I zokubekisa lokuqala kuyoba ukuhlolwa kwegazi, ultrasound kanye x-reyi. Nokho, kukhona izinkomba ukuthi kungenziwa esikalini futhi umnikazi. Lena ngokuyinhloko ukwehla ukusetshenziswa kwamanzi inja. Nokho, khumbula ukuthi ngemuva yezinkinga ingakha yokwelapha isilwane. Lokhu ukuhlanza futhi ngakhula ubuthakathaka, ukucobeka nokwenqaba udle. izimpawu ezinjalo kungase kubonise iziyaluyalu ezihambisana nezifo ezithile. Ngakho-ke, i-ubumsulwa imidwebo kufanele kwenziwe ukuhlolwa laboratory.

Imiphumela yokwelashwa

Singaba nethemba ngoba, uma kutholakale ukuthi une-Cushing Syndrome e izinja? Bangaki bahlala iziguli ezinjalo? Lemibuto ngokuvamile kakhulu ebuzwa abanikazi bezilwane. Mangisho ukuthi kuchazwe eselaphekayo kancane kuphela. Ngokuvamile, isikhathi sokuphila, ngisho nangemva yokwelashwa okuphumelelayo ingeqi iminyaka 2-3. C Lokhu kungenxa yokuthi Cushing Syndrome - iyisifo systemic sithinta bonke kwezitho izinhlelo, futhi uvusa izinguquko eziningi engelapheki. Lokhu zemisipha, izinhlelo senhliziyo futhi ethukile. Parallel kule isifo kunciphisa ukumelana umzimba ezifweni ezihlukahlukene, kanye, ukuze kuvuswe nokwanda okuphawulekayo blood pressure.