Umuthi 'Antistius ": analogue, yokusetshenziswa futhi impendulo

"Antistius" (international igama non-nokuphathelene - trimetazidine) - has Antihypoxanth senzo. Eqeda hypoxia nge nokubuyiselwa evamile amandla umzimba amaseli, umthamo nokulingana phakathi umoya-mpilo angenayo sasikhipha. IzEnzo ku sezinzwa cardiomyocytes ubuchopho, babanike izinto ezidingekayo.

Blocks anda uketshezi of-fatty acid, okuyizinto izimbangela eziyinhloko yeselula umzimba iziyaluyalu. Senhliziyo esilimele ephumula, kanjalo kunomthelela kuqiniswa of Kufinyeta esivimba amanzi. It sithuthukisa cell ulwelwesi, ukuvimbela ukunqwabelana therein potassium ion, i-calcium ne-sodium.

Pharmacokinetics

Ingqikithi asebenzayo (trimetazidine) ngokushesha futhi cishe ngokuphelele ugxile ubuningi isimiso sokugaya ukudla bungene. Digestibility "Antistius" cishe 90%. Ukuphumelelisa okuqukethwe esiphezulu egazini Kwenziwa amahora ama-2. Onqobayo kalula imingcele ephakathi igazi nezicubu. Sesibopho ukuthobisa plasma amaprotheni 16%. Excreted ngokusebenzisa izinso (angu-60% - ku isimo sokuqala). ephelele ukuqedwa isikhathi cishe 14 amahora. Abantu abaneminyaka engama-65 ukuthatha izidakamizwa, yinde isikhathi yokuzalanisa futhi amahora angu-24.

Khipha ifomu kanye nokwakheka

Ukulungiselela "Antistius CF" 35 mg № 60 (analogue ingatholakala umthamo ofanayo) ekhiqizwa ngesimo biconvex, amaphilisi round. Yikuphi tihlelwe kwi iziqukathi ekhethekile polymeric. "Antistius" ithebhulethi ngasinye siqukethe izingqimba ezimbili: i-nucleus kwangaphakathi noma has a luhlaza omhlophe noma aphuzi, igobolondo ngaphandle has lupus. Kokunye ithebhulethi "Antistius" equkethwe mg 20 we ketshezi eziyisisekelo - trimetazidine dihydrochloride.

Ukwakheka sihlanganisa izingxenye elisizayo, okuyinto amelwa magnesium stearate, hypromellose, triacetin, yensimbi oxide red yellow, ka microcrystalline cellulose.

Imiyalelo "Antistius"

Ukukhonza ngaphakathi ngesikhathi umthamo 40-60 mg, ihlukaniswe 2-3 Ukweqiwa. Kuye uhlobo ngobucayi isifo esimweni ngasinye liqoke Yiqiniso ekhethekile yokwelashwa.

isicelo

"Antistius" isetshenziselwa:

1. ukwelashwa kwesikhathi eside ischemia inhliziyo: nesixwayiso kungenzeka angina ukuhlaselwa (njengenhlangano izidakamizwa ezimele noma yimiphi izithako ukwelashwa).
2. Ukwelashwa kulimaze uhlelo vestibular futhi isitho ukuzwa (e t. H. Vertigo, tinnitus, ukuzwa umonakalo).
3. izilonda Umhlinzi umbono.

side effects

Kuningi iziguli abasebenzisa izidakamizwa, kukhona ukubekezelelana eliphezulu.

Akuvamile, kodwa kukhona abanye imiphumela engathandeki:

• ngehlangothini pheshana emathunjini - iziyaluyalu sohudo, ubuhlungu esiswini, isicanucanu, ukuhlanza, uhudo iziyaluyalu;
• umonakalo obangelwa ukuphazamiseka kwemizwa uhlelo, cranialgia kubonakala, discoordination ukunyakaza izimpawu extrapyramidal ukwehluleka obuzenza ukwehluleka kusukela "Antistius";
• the senhliziyo nemithambo yegazi - ukwehlisa ingcindezi, palpitations, okuvela kuyo arrhythmias;
• inombolo ukuncipha zegazi kwenzeka agranulocytosis;
• kungadala nemiphumela dermatological ngesimo ukuqubuka iguliswa futhi ukulunywa isikhumba.

Ezimweni ezingavamile, a-hepatitis anobuthi.

Ukusebenzisa "Antistius" kungavunyelwe:

• kwabesifazane abakhulelwe;
• ngesikhathi ibele;
• ezinganeni kanye intsha;
• nge kahle umsebenzi kwezinso;
• uma hypersensitivity noma ukungabekezelelani amanye izingxenye ngazinye ukulungiswa.

Sebenzisa lapho ekhulelwa noma ngesikhathi sokuncelisa ibele

Kuhlolwa izilwane luye lwabonisa ukuthi "Antistius" hhayi kungase kube nemiphumela teratogenic embungwini. Nokho, ngenxa lemali obanele of ulwazi mayelana nokwelashwa ephephile "Antistenom" ngesikhathi sokukhulelwa, ematfuba okuvela kwezinso ezahlukene kwengane esiswini angeke ngokuphelele wawususa. Yingakho abesifazane abakhulelwe ekumisweni umuthi azenziwanga ukwelashwa.

Futhi akunqunywa ukuthi "Antistius" ku ubisi lwebele. Uma igama elithi "Antistius" kuyadingeka, kubalulekile ukuba ayeke ibele.

Akuvunyelwanga ukusetshenziswa ezinganeni.

Ukuxhumana nezinye izidakamizwa

Akutholakali nokuxhumana imiphumela "Antistius", nge aphoyintimenti yayo kanyekanye neminye imithi.

Okwamanje, awusebenzi kubonisa Udaba olulodwa izidakamizwa ukweqisa izidakamizwa "Antistius" imfundo manual. Analogue zomuthi kabanzi.

Izixwayiso

"Antistius" 35 mg (kuhlanganise analogs) iqondiswa ukuze kuvinjelwe ukuhlaselwa okungenzeka angina, kodwa ayikwazi ukusetshenziswa impumuzo. Akunconyelwe ukuqashwa kukaNksz "Antistius" esigabeni sokuqala ekwelapheni isifo senhliziyo noma angina engazinzile.

Akuvunyelwe ukusetshenziswa ngesikhathi esisodwa utshwala kanye nokwelashwa "Antistenom" ngoba ezisebenzayo kukhona uhlobo okuphambene umthelela (ethanol futhi trimetazidine). Uma uphuthelwe eyodwa noma ngaphezulu izindlela imithi, akuvumelekile ukuyisebenzisa ngemithamo ephakeme isicelo esilandelayo.

"Antistius" akunamthelela izinga yokusabela futhi akabubangeli ukozela, ngakho ingasetshenziswa ukuphathwa komgwaqo.

Impilo "Antistius" izinyanga 36 kusukela usuku ukwakhiwa. Gcina ke endaweni eyomile, epholile futhi aphume kude nezingane. Njengoba evikelekile elangeni. Ayikwazi ukusetshenziselwa ngemva kosuku ukuphelelwa isikhathi, njengoba kungase kuzinciphise ukusebenza noma kubangele izimpawu okungafunwa.

Yini esikhundleni izidakamizwa?

On ukudayiswa kangakanani lesi sidakamizwa "Antistius" nozakwabo. Izibuyekezo kulo bayizinkulungwane esihle kakhulu. Mhlawumbe ukusetshenziswa kwezidakamizwa, olufana "Antistenom" mshini wezenzo:

• izimbali hawthorn;
• "Vazomaga";
• "Histochrome";
• "Dinatona";
• "Dibikora";
• "Doppelgerts Kardiovitala";
• "Ezafosfina lyophilisate";
• "Idrinola";
• amalungiselelo camphor;
• "Kardionata";
• "Qudesan";
• "Mexicor";
• "Meldonium";
• "Mildronate";
• sodium adenosine triphosphate;
• Neoton lyophilisate;
• "Orokamaga";
• "Riboksin";
• "Serotonin";
• "Taufon";
• "Ubinone";
• "Firazira" noma "Fosfadena".

"Antistius": nozakwabo Russian

• "Angiozyme kuthiye ukukhula." Kuyinto ethengekayo, kodwa nje njengoba donsile njengoba "Antistius" (ezishibhile analogue zingathengwa ngasiphi ekhemisi). It has legciwane enkulu yemiphumela emibi.
• "Vero trimetazidine" - isidakamizwa eshibhile.
• "Deprenorm MV" - e nokuqokwa kwakhe kwenzeka kahle emzimbeni okungatheni, kuyabiza.
• "Medarum" - cishe akukho imiphumela emibi, kodwa izidakamizwa kuyabiza kwezinye izikhathi.
• "Rimekor" - has a isikhathi eside yesenzo, imvamisa high amathuba okuba nemiphumela engemihle, eshibhile.
• "Karditrim" - evame kakhulu side effects, nozakwabo ezibizayo.
• "Tridukard" futhi "Trimektal" kangako, futhi yingakho akufanele isetshenziswe njengoba azithathi isikhundla izidakamizwa "Antistius".

Analogs futhi esikhundleni amazwe

• "Metagard" - lapho kuqokwa kaningi imiphumela emibi, kuba Analogue ezibizayo
• "Predizin" - side effects zenzeka kaningi.
• "Trimetazid" - has ayinayo imiphumela eminingi engemihle.
• "Prekard" - inguqulo ezishibhile kodwa ayisasebenzi.
• "Trimetazidine-Teva" - umuthi ezibizayo.

Izibuyekezo

"Antistius" (njengoba analogue) evame ukusetshenziswa yokwelapha yesimanje consequently ngempendulo kwaba ezihlukahlukene kakhulu. Iningi leziguli ekhuluma 'Antistene "njengendlela yokuthola ngempumelelo kakhulu.

Umuthi iye yasiza iziguli eziningi ukubika ukuthi isimo sabo jikelele ngcono, ubuthongo kwase kubuyiselwe, kukhona ingcindezi siphinde sibe nokuphila okuvamile. Ukukhuphuka kwezinga leminyaka yokuphila ezingaba khona. Umuthi elisusa inzululwane futhi imisindo ekhanda. iziyaluyalu Umhlinzi esweni "Antistius" kusiza ukubuyisela umsebenzi amehlo retina.

Kuphela inombolo encane izimo, uma usebenzisa izidakamizwa "Antistius" (kuhlanganise analogs), ngesikhathi ekwelapheni isifo senhliziyo, ukusebenza kahle ongaphakeme Kuye kwaphawulwa. Kungenzeka ukuthi kwakungase kwenzeke ngenxa ukuqhubekela phambili kwesifo noma zinikezwe iziyo ezingamahlalakhona.

Yiqiniso, wonke umuntu kufanele uqaphele ukuthi ukusetshenziswa "Antistius" asithinti noma kuqedwe ukwephulwa izinhlelo senhliziyo futhi ethukile. Lesi sidakamizwa izenzo kuphela njengoba ukweseka futhi njengendlela ukwesekwa. Ngezinye izikhathi ngisho odokotela fanele khonondo isidingo ukusetshenziswa kwezidakamizwa bemvelo ezifanayo, njengoba kunjalo ngokuvamile iziguli ngumnikazi ukulahla kwabo, ukuthatha kude lwemithi. Nokho, uma iziguli zithobele konke udokotela ekwelapheni, futhi umphumela onalesi sifo okwengeziwe ezimweni eziningi kuvela ngempela evumayo.

Ngakho, uma sisebenzisa "Antistius" (kuhlanganise analogs) njengoba izidakamizwa eyinhloko ekulweni inhliziyo ischemia, ungathola yi kancane. Nokho, ngekhono elingcono zomuthi ibangelwa, uma lisetshenziswe ukwelashwa njengendlela yokuthuthukisa umzimba amaselula. Iziguli basafunda imiphumela yayo, uma kuqhathaniswa nabangu izidakamizwa ezifanayo, ithuba lokufunda abasuse bese uzama ukuthola ukuthi iyiphi siphumelela ngokwengeziwe futhi ephephile?

Ngaphambi kokusebenzisa imithi kufanele kudokotela. Kodwa ukuze isipiliyoni kuphakheji ngalinye kukhona izidakamizwa "Antistius" imfundo manual. Ukubuyekeza, nozakwethu sezisetshenzisiwe ngokuningiliziwe.