"Tsiklovir" (amaphilisi): yokusetshenziswa zomuthi, ukuvezwa, analogs, ukubuyekezwa

Edinga amaphilisi "Tsiklovir"? Yokusetshenziswa, ukuphawula, izitatimende kanye analogue yalesi izidakamizwa izokwethulwa ngezansi. Uyofunda mayelana kangakanani kuwufanele kokukhuluma izidakamizwa, uma unazo Izimo, futhi yini imiphumela engemihle zenzeka ngokumelene isizinda wavuma.

Ukwakheka, emabhokisini incazelo futhi ifomu

wenza umuthi "Tsiklovir" ngayiphi indlela? Yokusetshenziswa zomuthi ibika it is ukuthi edayiswa amafomu alandelayo:

• Tablets. Isici esebenzayo ye thuluzi acyclovir. amaphilisi White Valium imakethwa e amaphakheji of nentaba, okuyinto yena, uphawu amakhadibhodi amabhokisi.
• "Tsiklovir" wamafutha. Imiyalelo (izicelo), abantu bangempela futhi odokotela bathi lokhu izidakamizwa iphumelela kakhulu. Namafutha kuyinto ayatholakala emakhemisi 5 g e amashubhu, uphawu emabhokisini amakhadibhodi.

Pharmacodynamics nomuthi

Indlela yokufaka isicelo wamafutha kanye amaphilisi "Tsiklovir"? Yokusetshenziswa ibika ukuthi izidakamizwa esebenzayo buyisidakamizwa zokwenziwa namagciwane. Ngenxa ukuxhumana lomcebo yayo iyasebenza nge cell enzyme, okuyinto washaya iphelela igciwane ayeke ukufanisana yabo.

Ngokwesimo sawo lo nomuthi kubhekwe has ukufana kwesakhiwo (chemical) kusuka dezoksiguanidina. Ngakho-ke, kalula ixubana synthesis DNA amagciwane ngokukhetha siba nethonya elilimazayo kubo.

Ngokusho imiyalelo, umuthi matasa ukulwa namagciwane ezifana upokisi, cytomegalovirus, Epstein-Barr igciwane futhi herpes simplex.

Pharmacokinetics

ngabe izidakamizwa amuncwa umzimba, "Tsiklovir" (amaphilisi)? Yokusetshenziswa ibika ukuthi inqubo ukumuncwa umuthi ngokwengxenye ngenxa emathunjini. I bioavailability isidakamizwa 20%. okuhlushwa sayo esiphezulu egazini waphawula ngemva 1-2 amahora ngemva kokuphathwa.

Uma ohlelweni igazi, esebenzayo izidakamizwa izidakamizwa sibopha ukuthi iprotheni ka 12-15%.

Kufanele kuqashelwe ukuthi izidakamizwa kalula zingene Bbb.

izinkomba

Lapho prescribers "Tsiklovir" (amaphilisi)? Yokusetshenziswa ibonisa ukuthi izidakamizwa senzelwe ukusetshenziswa letindzala kulezi zimo ezilandelayo:

• ekwelapheni ukutheleleka, okwakubekelwa okubangelwa herpes simplex virus, futhi varicella;
• nokuvimbela izifo, eyayibonakala cuphuluza le herpes simplex virus, futhi varicella (ikakhulukazi abantu encishisiwe isimo mzimba);
• njengengxenye yokwelashwa eziyinkimbinkimbi in iziguli immunodeficiency okukhulu (kubandakanya i-HIV ukutheleleka), kanye nabantu abaye zabhekana umnkantsha transplantation;
• nokuvimbela ka cytomegalovirus ukutheleleka ezigulini.

Njengoba for ifomu wendawo zomuthi, it is ngenkuthalo lisetshenziswe umkhuba amehlo (kuhlanganise ne keratitis nomunye umonakalo iso, okwakubekelwa okubangelwa herpes simplex virus).

Ngaphandle ukusetshenziswa kwezidakamizwa ikhonjiswa nge izifo zesikhumba, eyayibonakala ukusebenza okubangwa yileli gciwane herpes simplex futhi varicella.

Izimo

Yiziphi ngezimo zesiguli linqume ukuvinjelwa izidakamizwa "Tsiklovir" (amaphilisi)? Yokusetshenziswa Ngokusho la Izimo:

• ibele;
• hypersensitivity yokusabela kuya izingxenye aphansi nezamabanga aphakeme zomuthi;
• izingane ezingaphansi kweminyaka emibili ubudala ngoba;
• ngesikhathi sokukhulelwa.

Izidakamizwa "Tsiklovir": yokusetshenziswa

"Tsiklovir", ukubuyekezwa zazo ethulwa ekupheleni isihloko, buyisidakamizwa ngempumelelo kakhulu namagciwane. Isikali Kwalo izindlela yokusetshenziswa kufanele azimisele kuphela udokotela. Uma ungakwazi ukuya kudokotela, kufanele uhlole ukuthi yini imiyalelo okuvalelwe ngokucophelela.

Ngayiphi umthamo ezinqunyiwe isidakamizwa "Tsiklovir" (amaphilisi)? Imiyalelo isicelo ibika ukuthi izidakamizwa kumele kuthathwe ngomlomo. iziguli kwabadala kanye nezingane kusukela kwabaneminyaka emibili izidakamizwa elibekelwe 200-400 mg kathathu noma kahlanu ngosuku.

Uma kudingeka, umthamo ibalwa amaphilisi isikimu ezilandelayo: 20 mg / kg (isb, kuze 800 mg umthamo ngamunye) kane ngosuku.

Uma reception "Tsiklovira" ingane kudinga isikhathi esingaba iminyaka emibili, iqondiswa e inani elilingana 1/2 umthamo for iziguli omdala.

Ubude yokwelashwa nale izidakamizwa 5-10 izinsuku. Lapho nokwehluleka ukusebenza kwezinso zidinga ukulungiswa kokudla nokufakwa lwemithi.

Indlela yokufaka isicelo namafutha?

Imali ebekiwe kahlanu ngosuku ngokuthi "Tsiklovir" izidakamizwa zendawo zangaphandle. A ungqimba elincanyana wamafutha isetshenziswa endaweni ethintekile kanye ishiywa kuleli fomu amahora ambalwa. Njengoba isikhathi sihamba, imithi ngobumnene isuswe nge disk ukotini futhi enze reapplication.

Leli fomu zomuthi kuhle ukusebenzisa emva izilonda abandayo bazocula phezu kwesikhumba. ukusebenza kwalo kuboniswa kuphela lapho Bubbles uqale aqhume. Ngenxa yalokho, umthelela wendawo wamafutha ukutheleleka akusho basakazekela kwezinye izindawo isikhumba.

side effects

Ngeshwa, reception zomuthi kubhekwe ikhuthaza sebuningini amathuba okuba nemiphumela engemihle. Ukusetshenziswa amaphilisi, ngisho ngemithamo Kunconywa udokotela ungaphikisana isicanucanu, ukuqubuka kwesikhumba, ukuhlanza, ubuhlungu besisu, uhudo, ikhanda elibuhlungu, ukutubeka komzimba, isiyezi, imfiva, kwehle okuhlushwa, ukozela, ukuhhema nokuqwasha.

Lokhu umuthi izimbangela ezingavamile kakhulu nezinwele, ukukhuphuka lezivakashi e lokuhlushwa bilirubin egazini, creatinine, urea futhi isibindi enzyme, kanye lymphocytopenia, erythropenia futhi leukopenia.

Njengoba ukusetshenziswa wendawo "Tsiklovira", ngokuvamile kubangela olukha phezulu punctate keratitis, umuzwa esivuthayo endaweni isicelo, kanye conjunctivitis futhi blepharitis.

Lapho isicelo ihlelwe ngokulandelana kwezihloko e yokugcoba endaweni kwesicelo nazo zingaba khona esivuthayo isasasa. Ngaphezu kwalokho, isiguli bangezwa ukuqubuka kwesikhumba, uyaxebuka, ukulunywa, womile, erythema. Uma kubhekwa umuthi nemiyalezo hit phezu ulwelwesi lwamafinyila, kunobungozi ukuvuvukala.

amacala ukweqisa izidakamizwa

Ngemithamo okweqa nomuthi "Tsiklovir" nesineke bangase balwisane kwagcizelela ohlangothini ukusabela. Izimo ezinjalo ngempumelelo ziphathwe lavage esiswini hemodialysis, ukwethulwa plasma bese plasma olwandisa.

Ukuhambelana neminye imikhiqizo

Njengezinye ekusebenzisaneni izidakamizwa izidakamizwa "Tsiklovir"? Nge inhlanganisela izidakamizwa ne probenecid encishisiwe uketshezi ijabulise lomcebo asebenzayo. Ngaleyo ndlela kwande isigamu-ukuphila ne-plasma yayo okuhlushwa.

reception Kanyekanye "Tsiklovira" nabenzeli nephrotoxic kwandisa ingozi nemiphumela nephrotoxic, ikakhulukazi abantu kahle izinso umsebenzi.

Umthelela "Tsiklovir" izidakamizwa inyuka ngenkathi ethola immunostimulants.

izincomo ezithile

Kuyinto engathandeki ukuba linqume izidakamizwa umbuzo kulabo ukwephula sína umsebenzi izinso. Lapho ethola "Tsiklovira" uqaphele ukuthi kungabangela ukuthuthukiswa ukwehluleka oyingozi kwezinso. Lokhu kwenzeka ngenxa ukwakheka kodaka ngesimo zinhlayiya lomcebo asebenzayo.

Ukwelashwa ezigulini esezikhulile lufanele lwenteke kulamazinga lalandzelako kanye umthwalo amanzi anele ngaphansi kokuqondisa okuqinile udokotela.

Uma samabhamuza ezithweni zangasese liyadingeka ukuze zigweme ukuthintana ngokocansi, kusukela ukusetshenziswa "Tsiklovira" akuvimbeli yokudlulisela igciwane.

Izindleko kanye analogue

Miselela "Tsiklovir" kungaba izindlela ezinjalo, "Acyclovir", "Acyclovir-Vishfa", "Acyclovir-Farmak", "Valvira" nokunye.

Inani kubhekwe izidakamizwa akusilo eliphezulu kakhulu. Thenga le umkhiqizo nenani amaphilisi 10 kungenzeka zingabi ruble 20-30.

nobufakazi

Manje uyazi ukuthi kuyinto izidakamizwa "Tsiklovir". Imiyalelo, ukubuyekezwa, ubufakazi okwethulwa mathiriyeli lo sihloko.

Ukuqhuma kwezintaba-mlilo Herpetic ngezikhathi ukuphazamisa abantu abaningi. Ngakho-ke, amaphilisi kanye wamafutha eklanyelwe sibaphathe, athandwa kakhulu. Iziguli zithi izidakamizwa "Tsiklovir" kubonakala kuphela ohlangothini oluhle. Isisiza ukuqedwa okusheshayo Izilonda, eyayibonakala ukusebenza okubangwa yileli gciwane herpes. I ethile kuphela umuthi khona eminingi engemihle.