"Tinidazole": lokho waphulukisa, wakhipha imiyalelo, Izimo

Uyini izidakamizwa "Tinidazole"? Kusukela lokho ephatha lokhu izidakamizwa? Thola izimpendulo zale mibuzo, uzokwazi ukuba kulesi sihloko. Kanti futhi kuhlinzeke imininingwane ngokufinyelela kwi ukuthi nozakwabo sebeyicwaningisisile izidakamizwa, okuyinto libuyekeza ngakho kushiya ogulayo nokuthi kubiza e ekhemisi ngamaketanga kakhulu.

Ukukhululwa ifomu zomuthi, kwikhava yawo, ukwakheka

Yini fomu esivela izidakamizwa "Tinidazole"? Izibuyekezo zithi lokhu izidakamizwa akhiqizwa ngendlela amaphilisi, okuyinto camera nge enamathela ekhethekile.

Isithako esemqoka yalolu umuthi tinidazole. Futhi, ifaka izinto ezengeziwe, okuyinto zivezwa alginic acid, microcrystalline cellulose, magnesium stearate, sodium lauryl sulphate kanye isitashi.

amaphilisi Ngokuphathelene emgodleni, liphethe ama-titanium dioxide, propylene glycol futhi hydroxypropyl methylcellulose.

Izidakamizwa "Tinidazole", lapho imfundo kuqukethwe ebhokisini amakhadibhodi, phama amabhamuza amaphilisi 4.

izakhiwo Key

Siyini "Tinidazole"? Kusukela lokho uphulukisa kusho? Ngokusho imfundo, ibhekisela asebenzayo izidakamizwa antiprotozoal nezidakamizwa umbukiso imakwe izakhiwo elwa namagciwane.

Umgomo we operation ye nomuthi esekelwe ukulimala kwe-DNA futhi okusithiyayo zokuphindaphinda kwamagciwane. Ubelokhu ngempumelelo ikakhulukazi ngokumelene eziphilayo ezifana Entamoeba histolytica, Lamblia intestinalis futhi Trichomonas vaginalis.

Kumele kuqashelwe futhi ukuthi izimali kunomphumela amagciwane ngokumelene amagciwane anaerobic.

izinkomba kinetic

Izidakamizwa "Tinidazole", intengo olubonakaliswa ekupheleni isihloko, has ngezinga eliphezulu ukumuncwa. bioavailability wayo 100%.

Ukuxhumana zemithi plasma amaprotheni 12%. tinidazole isiqongo lokuhlushwa igazi waphawula ngemva kokuphathwa temlomo na ngemuva kwamahora amabili imayelana 40-51 mcg / ml. Ngemva olunye usuku, kumayelana 11-19 mcg / ml, futhi ngemva kwamahora angu-72 - 1 UG / ml.

Ithuluzi kuncike lingena isithiyo esinomhlapho kanye kusivimbeli gazi ebuchosheni. Futhi, kuqokonyiswe nge ubisi lukamama amahora 72 emva ukungenisa.

Umzimba kwenzeka nomuthi isibindi. Kulesi uhlobo nemikhiqizo pharmacologically asebenzayo hydroxylated, okuyinto ukucindezela ukukhula kwamagciwane anaerobic futhi umphumela yokugcizelela ka tinidazole.

isigamu-ukuphila kubhekwa ekwakhiweni Isikhathi amahora 12-14. Balinganiselwa ku-50% we-nomuthi uboniswa kanye Bile. Ngale ngelosi izinso esiboniswe inani 12% (ngesimo derivatives) kanye 25% (akushintshiwe).

Nomuthi "Tinidazole": yini ephatha?

I izinkomba yalesi izidakamizwa zingezinye zezifo ezilandelayo:

• trichomoniasis;
• nokuvinjelwa anaerobic izifo (nasezinkingeni ezilandela ngemva kokuhlinzwa);
• giardiasis;
• wokuqeda Helicobacter pylori (lihambisana amaphilisi noma amalungiselelo bismuth) ;
• amebiasis (kuhlanganise ifomu hepatic);
• ukutheleleka aerobic-anaerobic okuxubile (ngokuhlanganyela imithi engama-antibiotic);
• izifo ezibangelwa amagciwane anaerobic.

Enqabelo ukuthola izimali

Manje uyazi ukuthi kuyinto izidakamizwa "Tinidazole". Kusukela lokho uphulukisa ingumuthi, nathi utshele ngenhla.

Ngokwe-ticondziso letivela izidakamizwa ngaphansi ukucatshangelwa kukhona Izimo. Isimo ezilandelayo ziqondise kubo:

• ukwephulwa inqubo hematopoiesis;
• isifo organic we CNS;
• senyanga yokuqala nokukhulelwa;
• ibele;
• hypersensitivity kuya tinidazole nezinye nemikhiqizo 5-nitroimidazole.

Izidakamizwa "Tinidazole": yokusetshenziswa

amaphilisi kuhlongozwe zenzelwe abaphathi ngomlomo. Zivame umthamo ibalwa kumuntu ngamunye, kuya ngohlobo sifo tolerability zomuthi yisiguli.

Abadala isidakamizwa iqondiswa e umthamo 1.5-2 g kanye ngosuku. Njengoba for the kids (hhayi kuphela ukuze kuvikelwe nasezinkingeni ezilandela ngemva kokuhlinzwa anaerobic izifo), abazincomayo ukusetshenziswa 50-75 mg / kg kanye nsuku zonke.

Isikhathi salesi ukwelashwa ekufinyelelwa kuso ngokubheka udokotela futhi kungaba mayelana 2-10 izinsuku.

Phenomena ngu-uhlamvu

Izidakamizwa "Tinidazole" kusukela ukhunta nezinye izifo kungabangela imiphumela elandelayo ezimbi:

• CNS futhi PNS: isiyezi, dysarthria, ikhanda, ukukhathala kakhulu, ukuquleka, incoordination, peripheral neuropathy, ubuthakathaka.
• Ukugaya: uhudo, sokuzincisha, kome umlomo, isicanucanu, ukunambitheka metallic emlonyeni, retching.
• Yokungezwani komzimba: ukuqubuka, ukuqubuka kwesikhumba, ukulunywa, angioedema.
• Okunye: leukopenia lezivakashi.

izidakamizwa ekuhlanganyeleni

Ngingakujabulela yini neminye imithi imithi "Tinidazole"? Izibuyekezo bathi ngokwabelana ukucabangela izidakamizwa nokuthuthukiswa Ethanol disulfiramopodobnyh umphumela.

Ibele nokukhulelwa

Izidakamizwa "Tinidazole" contraindicated ukuthola engxenyeni yezinyanga ezintathu zokuqala zokukhulelwa. Ukusebenzisa izidakamizwa e-trimesters lesibili nelesithathu kungenzeka kuphela uma izinzuzo ehlosiwe komama esizayo zinkulu izingozi ingane yakho.

Uma lokhu kusho ukuthi asikho isidingo sokuba uthathe ngesikhathi ibele, kubalulekile ukuxazulula udaba ehushule lactation. Njengoba yaziwa, tinidazole ezinqunywe ubisi lukamama amahora 72 ngemva kokuphathwa.

izincomo ezithile

Esikhathini ekwelapheni izifo ezifana trichomoniasis kuyadingeka lokufeza ukwelashwa kanyekanye kwabo bobabili abashadile.

Ngo inqubo ukuthatha izidakamizwa kufanele uyeke ukuphuza utshwala.

Lapho imiphumela engemihle CNS izidakamizwa amankeyane.

Lapho ethola tinidazole umchamo kungenziwa ababethi umbala omnyama.

Uma impatho isiguli kwaqhubeka izinsuku ezingaphezu kuka-6, ukuqapha okuqhubekayo wegazi isithombe kufanele sigcwaliswe.

Ngokuba nokuvimbela anaerobic izifo (nasezinkingeni ezilandela ngemva kokuhlinzwa) Isikali zomuthi engakaze isungulwe izingane ezingaphansi kweminyaka engu-12.

Esikhathini esiyiminyaka ukwelashwa okufanele ibhekwe njengelungelo izindlela uyeke imisebenzi imisebenzi eyingozi.

Inani, analogue, umthengi Izibuyekezo

Kungakanani kukhona "Tinidazole" ithebhulethi? Inani lentengo lomuthi kuyinto ruble angu-30. Ukuze abathengi lanamuhla, izindleko ezifana zomuthi kwamukelekile.

Umuthi ungayithola enye "Tinidazole"? Analogue kwaleli thuluzi kuzoholela uhlu njengamanje: "Tiniba", "Fazizhin", "Vero Tinidazole" futhi "Tinidazole Acre."

Amazwana ngalokhu imithi ikakhulukazi omuhle. Iziguli zithi izidakamizwa nobunzima kahle giardiasis futhi trichomoniasis. Nokho, abanye abasebenzisi ukubika ukuthi "Tinidazole" ngokuvamile kakhulu kubangela isicanucanu, retching nesiyezi.