"TAYVERB" (lapatinib) intengo analogue. Njengoba ukuthenga Tayverb?

Ngokusho idatha yakamuva, eRussia minyaka yonke, 54 000 abesifazane unomdlavuza webele kutholwa. Futhi lokhu uphethwe isigamu enhle lwesintu, ngeshwa, kuningi ozokuzwa futhi kaningi. Kodwa imithi akemi namanje. amathuluzi amahle isakhiwa zokunqanda isifo esibi. Omunye wabo "Tayverb". Yokusetshenziswa komkhiqizo wathi kanye Tykerb yayo ejwayelekile siyonikwa kwesikhathi kulesi sihloko.

Lapho izidakamizwa kungenzeka Tykerb futhi "Tayverb" ukuthenga eshibhile?

I Russian Federation kanye izidakamizwa uphawu, futhi analog yayo kungenziwa yayala bese uthenge endaweni inkampani abadumile Indian owayedume okuqinile, WWW.ONKO24.COM. Ngesikhathi esifanayo ukuze kunikezwe ngesevisi udinga khona imibhalo eqinisekisa isidingo sokwelashwa.

On "Tayverb" intengo (ngoba izidakamizwa uphawu) e Moscow, isibonelo, manje igcinwe uhla ruble 163.000. Nakuba ukuthenga ejwayelekile izobiza ruble 40.600. Njengoba ubona, umehluko libalulekile. Ngakho-ke, labo "Tayverb" ukuthenga eqolo, Tykerb ejwayelekile izotholakala oshumayela ungagcina impilo ngisho nokuphila.

Mayelana Imithi ejwayelekile izidakamizwa

izidakamizwa IsiZulu kuchaziwe - Tykerb, oluqanjwe GlaxoSmithKline (India). It has ketshezi eliyisisekelo elifanayo iyasebenza, futhi umphumela ke ngokuphelele ezifanayo. Kodwa iziguli ukugula nzima kakhulu futhi baphoqeleka ukuba bachithe isikhathi imali eningi ekwelashweni, kungaba ezingabizi kakhulu ukwedlula yegama lomkhiqizo lesi sidakamizwa "Tayverb".

Phela, akuyona imfihlo ukuthi lapho kukhululwa le imithi ejwayelekile inkampani, okuyinto wathola ilayisense, musa ukuchitha imali ukuthuthukiswa, ukuhlolwa kanye nokukhangisa, ngakho izindleko kanye intengo ka imithi kakhulu ephansi. Futhi lokhu, ngenhlanhla akuphazamisi ukusebenza zomuthi kukhiqizwa.

Lapho izidakamizwa isetshenziswa

The main isithako ngokuthi ejenti kuyinto inhibitor tyrosine kinase - lapatinib. It kuvimbela isenzo asabekayo amaprotheni tyrosine kinase, ngenxa okuyinto uguqule amaseli enempilo.

Enjalo lapha amaprotheni-molecule futhi HER2 receptor. Basuke esisogwini ulwelwesi ebusweni webele noma ngaphakathi engqamuzaneni, futhi esimweni overexpression ophoqelelwe kula maseli ngenkuthalo uhlukanise angalawuleki, futhi lokho kwenza ukuthuthukiswa isifo nolaka ikakhulukazi.

Ezimweni ezinjalo, prescribers "Tayverb". Ivame kuhlangene 'capecitabine "iziguli isifo endaweni eziphambili noma metastatic ngubani ngilugcinile Ukudlondlobala kwalesi sifo ngemva" Trastuzambom "yokwelapha kanye kungemuva yayo. Futhi ejenti ngempumelelo echazwe lihambisana i inhibitor aromatase kwabesifazane postmenopausal e uphethwe hormone yokwamukela-HIV umdlavuza metastatic.

Njengoba lisetshenziswe "Tayverb": isitatimende

Uchaza amathuluzi atholakalayo ngesimo amaphilisi okumele zithathwe kuphela kadokotela, kanye ngosuku, ihora elilodwa ngaphambi noma ihora ngemuva kokudla. Isikhawu phakathi esenikwe nomuthi kufanele kube amahora angu-24, futhi kuyinto engenakwenzeka ukuba kuncishiswe.

Uma kwenzeka ndima okungalindelekile ka isikhathi esimisiwe it is kakhulu Kunconywa ukuba ulinde kuze umthamo olandelayo.

Dose uzimisele kuye ngokuthi uhlobo lwesifo:

• Ngakho, iziguli zokugula metastatic kuba 1250 mg "Tayverb" ekwakhiweni kanye 2000 mg "Capecitabine".
• Endabeni izimila-hormone okuthiwa i-sensitive, ethola 1500 mg phansi izidakamizwa i inhibitor aromatase e isamba 2.5 mg.

Izimo

Ichaza indlela is contraindicated phakathi nokukhulelwa kanye lactation. It akukashicilelwa izingane, njengoba ngolwazi olwanele umthelela isidakamizwa umzimba wengane akusilo. Ngokuqapha ezinqunyiwe iziyaluyalu kwesibindi, ukwehluleka kwezinso (for iziguli engaphezu kwengu-65) futhi ezimweni engaholela kwesokunxele ukwehluleka ventricular.

side effects

Amalungiselelo equkethe lapatinib, kungabangela imiphumela emibi. Ngakho, ngo-iziguli yokuvuma "Tayverb" amaphilisi sivame ukuba buthaka, izimpawu ze-anorexia ne encishisiwe LVEF (okuyinto kwenzeka ikakhulukazi asymptomatic futhi abuyiselwe ukususa izidakamizwa). Futhi unezimpawu sohudo endaweni, ukuqubuka kwesikhumba (ukuphasa bebodwa futhi asidingi ukuqedwa zomuthi) kanye nail izifo.

Ukwelashwa nokuvikelwa ithuluzi kufanele kuphela kwenziwe ngaphansi kokuqondisa esiqinile of onguchwepheshe!