"Metodzhekt": ukubuyekezwa samathambo, ikakhulukazi isicelo futhi ukusebenza

rheumatoid arthritis iyisifo elisezweni esiteji ezingamahlalakhona. Ngeke waphulukisa, kodwa ungakwazi ukubambezela yonke ukuqhubeka kwesifo kanye ukuvimbela okuvela kuyo ukuxakeka. Kulesi simo, iphathwa immunosuppressants. Ukuze labo nje ahlobene nezidakamizwa "Metodzhekt". Ukubuyekezwa samathambo uqaphele ukuthi imithi engathathi isinyathelo ngokushesha, kodwa ngemva kwezinyanga 2-6.

"Metodzhekt": Ukwakheka, Ukwakheka

It ikhiqizwa ngefomu isixazululo kwezokuphatha komjovo nomuthi "Metodzhekt". Izibuyekezo ne -rheumatoid arthritis usho izidakamizwa uma kusetshenziselwa njalo, kancane kancane kususa ukuvuvukala kwamalunga. Kuyasiza ukubuyela ekuphileni okuvamile.

Izidakamizwa zisekelwe ingxenye esebenzayo ye methotrexate disodium. izithako amancani alinganiswa amanzi distilled, futhi i-sodium chloride futhi hydroxide.

Umuthi ikhiqizwa isipetu uphawu senzelwe umjovo. I isipetu kungenzeka 7,5- 25 mg isixazululo nemijovo. Ibhokisi iqukethe:

• ingilazi isipetu;
• umlomo wombhobho plastic;
• inaliti igcwele ngendlela ibhamuza ekhethekile;
• imfundo manual.

Isixazululo has a ukuphila eshalofini kweminyaka emibili. Ikhishwa eJalimane.

izakhiwo kwemithi

Libhekisela immunosuppressive nemithi antimetabolite "Metodzhekt" (izimpendulo rheumatoid arthritis abonisa ukuthi izidakamizwa ngemva ishuthekwe umzimba kungabangela ukucanuzelelwa inhliziyo kanye nesiyezi). Umuthi libhekene anti-isimila izakhiwo. Kuyinto omelene folate. Inciphisa dihydrofolate reductase, okuyinto ethatha ingxenye ukuvuselelwa dihydrofolic acid ku tetrahydrofolic. Ingqikithi asebenzayo lapha ukhonza njengelungu yenethiwekhi carbon izingcezwana kubalulekile ukuze asize ngokuhlanganisa ka purine nucleotide nemikhiqizo yabo.

Umuthi kuvimbela DNA zamagama kanye nokulungiswa. Kuvimbela iseli mitosis. Methotrexate kakhulu kuthinta bystroproliferiruyuschie amaseli ezihlobene umnkantsha, izicubu embryonic, izimila ebulalayo mucosal epithelium.

Ngokuphumelelayo e psoriatic ne-rheumatoid arthritis. Esikhathini yokwelapha lezi zifo futhi ziphephile izidakamizwa i immunosuppressive eqeda ukuvuvukala ngokwemvelo. Umphumela omuhle imishanguzo ngenxa lokuhlala ukwanda adenosine ku ukuvuvukala inqubo zone.

izinkomba

Uphenyo "Metodzhekte" ibonisa ukuphumelela izidakamizwa. Lo mbhalo uthi it is ibekezelelwe kahle futhi kungakubangeli engemihle.

Sebenzisa imithi nge -rheumatoid arthritis kanye arthritis, samathambo engamahlongandlebe kuhambisana ezingamahlalakhona eziyinkimbinkimbi futhi ezikhulayo ngentshiseko.

Izimpawu I-imijovo ukhonza njengomdala arthritis psoriatic, futhi psoriasis generalized. Kulo mBhalo, "Metodzhekt" lisetshenziswa lapho ukwelashwa okujwayelekile zehlulekile.

Izimo ukusetshenziswa

Lo mbhalo uthi kahle kuyasiza izidakamizwa "Metodzhekt" I-i-rheumatoid arthritis, i-review. Awukwazi ukusebenzisa umuthi uma umsebenzi isibindi normal, ukuhlukumeza iziphuzo spirituous, ukwehluleka kwezinso in a sigaba nzima yentuthuko.

Kufanele ubeke phezu kwakho izidakamizwa ne umnkantsha hypoplasia, igazi kakhulu, leukopenia, futhi thrombocytopenia. Akunakwenzeka ukujova e pathologies ezithathelwanayo egqoke chronic oyingozi. Engamiswanga izidakamizwa izilonda emathunjini we ngalo ingaphakathi ngomlomo kanye ipheshana emathunjini.

Ungasebenzisi izidakamizwa in iziguli ukuntula mzimba ezinzima, wakhulelwa futhi abesifazane lactating. ukwelashwa izidakamizwa is hhayi kwenziwe kanyekanye ne kwemithi yokugoma bukhoma. Izimo ukusetshenziswa esetshenziswa izakhi abamelwe hypersensitivity kuya nomuthi.

Sebenzisa imithi ngokuqapha kumele kube abantu abaphethwe ascites, emathunjini ipheshana isimiso, amanzi emzimbeni. Ngaphansi kokuqondisa kukadokotela, kufanele babe nesineke effusion pleural noma peritoneal, kanye nabantu nokwehluleka ukusebenza kwezinso. Nge-ejenti ukunakekelwa isetshenziswa izifo ezithathelwanayo, fungal, amagciwane kanye yisinanakazana. Futhi yayihlanganisa kukhona abantu abaphethwe zoster elula herpes, isimungumungwana, iziguli inkukhu Pox amakhulu, iziguli ezinemishini strongiloidozidom futhi amebiasis.

iziguli Adult yokuzala ekwelapheni imithi kumele usebenzise zokuvimbela inzalo ethembekile. Kufanele ivikeleke ngemuva kokuphela yokwelapha izinyanga eziyisithupha. Uma umuntu wesifazane ukhulelwa kanjani ngesikhatsi ukwelashwa, kubalulekile ukuba sicabangele ingozi nemiphumela engemihle zomuthi embungwini.

Methotrexate ludlulele ngaphakathi ubisi lwebele futhi zingaba yingozi ingane. Ekwelapheni "Metodzhektom" Kufanele uyeke webele ukusuthisa ingane yakho ngesikhatsi ukwelashwa.

nokushintsha kokudla nokufakwa

Iphathwe phansi kwesikhumba, ngemithambo yegazi futhi izidakamizwa intramuscularly "Metodzhekt". Yokusetshenziswa nempendulo Kunconywa ukusebenzisa izidakamizwa kanye ngesonto, ngesikhathi esifanayo. Ubude besikhathi sokwelashwa elawula udokotela.

Abadala ngemithi rheumatoid arthritis elibekelwe 7.5 g kanye ngesonto. Umzila yokuphathwa kungenzeka iyiphi. Kufanele uqale nge umthamo ephansi. Uma kahle ikubekezelele nesineke, umthamo liyakhula kancane kancane nge 2.5 mg ngeliviki. Isonto esiphezulu izinga elilingana 25 mg.

Umphumela ubonakala ngemva kwamasonto 4-8 of Ukuqalwa ukwelashwa. Uma iphethwe ukususa izimpawu zesifo, umthamo kancane kancane esiphansi. Inkambo zokwelapha ingahlala iminyaka eyishumi noma ngaphezulu.

Ekwelapheni ka psoriatic sokuqaqamba kwamalunga kanye psoriasis iviki ngaphambili Ukuqalwa yokwelapha Kunconywa ukwethula umthamo yokuhlola yama-5.10 isixazululo mg ukuze kutholwe amathuba okuba nemiphumela engemihle.

Uma kukhona imiyalelo akekho omunye udokotela, kufanele uqale nge 7.5 mg kanye ngesonto. Umthamo liyakhula kancane kancane. Akumele iqondiswa masonto onke phezu 25 mg isixazululo. Ubuningi umthamo kuvunyelwe seviki mg 30 psoriasis. Umphumela ubonakala ngemva kwamasonto 2-6. Ngemva kokufinyelela siletha imiphumela efiselekayo, umthamo kuyehla.

Abantu nge sezinso futhi yokwehluleka kwesibindi, kanye izidakamizwa abadala kufanele siyisebenzise ngokuqapha.

Izingane ezingaphansi kweminyaka engu nesithupha ukuthi nginesifo sokuqaqamba kwamalunga engamahlongandlebe kufanele ngiphuze umuthi ngesilinganiso 10-15 mg / m ² of surface body. Umthamo kungase kukhule kuze kufike e-standard 20 mg / m ^2. Izingane zikhuthazwa izidakamizwa iqondiswa intramuscularly.

Ukuvimbela imiphumela emibi, odokotela linqume ngosuku olulandelayo ngemva umjovo we-folic acid zinsiza, phezu Phakathi nezinsuku ezinhlanu ezalandela. Ngaphambi umjovo, futhi ngosuku kumiswa vitamin B9 awukwazi uphuze izidakamizwa.

Izidakamizwa nge nomphumela ofanayo

Uma "Metodzhekt" engafiki ukuze ayokwelashwa, udokotela angase esikhundleni kwezidakamizwa omunye, ezifanayo ukwakheka kanye wesenzo. Ngu analogs ezivamile "Metodzhekta" zihlanganisa:

• "Vero Methotrexate."
• "Zeksat".
• "Metortrit".
• "Methotrexate".
• "Methotrexate-Teva".
• "Treksan".
• "Triksilem".
• "Evetreks".

Lezi kanye nezinye analogs kalula esikhundleni izidakamizwa, kodwa kumele akhethwe udokotela ukuba khona.

izindleko

Nakani zibiza kakhulu "Metodzhekt" Izibuyekezo izidakamizwa. Ngo-rheumatoid arthritis (intengo yale umuthi emhlabeni 600-750 ruble ngayinye 0.75-1 ml, ngoba ruble 800-1400, ungakwazi ukuthenga 1.5 kuya 2.5 ml ukulungiswa) abangekho kufanele ukhethe. Lesi sifo sidinga esegumbini labagula kakhulu. Yikuphi, ngeshwa, kuyinto ngempela eqolo.

Ixwayisa ngokuthi isidingo ukungena izindlela masonto onke "Metodzhekt" imfundo manual. Ukubuyekezwa (intengo ngenhla izinto ingase yehluke kuye ngesistimu iphuzu ekhemisi) zibonisa ukuthi izindleko izidakamizwa impela high, kodwa naphezu kwalokhu, umuthi kunikeza Chile omuhle.

Ukuphumelela lomuthi

Qaphela ukuthi wenza ukuphila kwangempela ekulweni rheumatoid arthritis izidakamizwa "Metodzhekt" ukubuyekezwa. Ukuphumelela izindlela wazibonakalisa eziningi abantu.

Ukujova izidakamizwa ivumela izidakamizwa ugxile ngokuqondile egazini, ngokudlula esiswini namathumbu. Le ndlela yokusebenzisa unika ngekhono elingcono kuka imithi ngomlomo.

"Metodzhekt" ngesisekelo methotrexate libhekisela eziyisisekelo Ukuguqula ejenti enqanda ukuhlasela kwesifo samalunga. It has izakhiwo eziqinile eqeda ukuvuvukala. Ingasatshenziswa angefani-rheumatoid arthritis. It sishintsha inkambo sifo. Asetshenziswa nobuhlungu, ukuqina kanye nokuvuvuka kwamalunga.

Umuthi zisiza abantu abaningi ukuba uphile ukuphila okuvamile, ngiyasebenza. It kubamba ukuqhubeka inqubo isifo futhi ukulimala uqwanga articular nezicubu. Umthelela sokuqondisa izidakamizwa waphawula futhi ngemuva kwezinyanga eziyisithupha.

Uphenyo odokotela

Isikhathi esining impela, ukwelapha isifo samathambo udokotela okunqunyiwe "Metodzhekt". Uphenyo odokotela bathi ayivamile ukubangela side effects kanye is kahle ikubekezelele iziguli. Kuthathwa enye immunosuppressant engcono. Ingasetshenziselwa ukuze ulondoloze impilo sonke isikhathi, iminyaka eminingi.

Umuthi kuyinto anobuthi, futhi ngenxa yalokho, lapho lusetshenziswa, odokotela beluleka ukugcina wesifunda sokuqondisa futhi umthamo. Ngezelela noma ukunciphisa umthamo kancane kancane futhi kuphela ngaphansi kweso lwezokwelapha. Lokhu kuzovimbela yezinkinga kungenzeka. Bonke abesifazane welashelwa nge "Metodzhekt", odokotela batusa ukusetshenziswa zokuvimbela inzalo ethembekile njengendlela yokuthola kungathikameza kabi i-fetus.

Izibuyekezo ukusetshenziswa ezinganeni

kuphela enemithi kumele kusetshenziswe "Metodzhekt". Ukubuyekezwa rheumatoid sokuqaqamba kwamalunga e izingane ukhulume umphumela omuhle, onikeza imithi. Ezinganeni, iqondiswa e 2 ml kanye ngeviki. Ezinye guys abangekho ngaphambilini babenezinkinga amalunga omzimba ngemva imijovo athoma ukubaleka, ukuba abe matasa. Banakekela ukufeza eside ukuthethelelwa sifo bese wehlisa ijubane.

Izingane ababephathwe "Metodzhektom" akahlukile ontanga yabo. Badlala eziningi, futhi ubuhlungu emalungeni kuphele ukuphazamisa kubo. Sinenkosi nemilenze kancane avuvukele emaqakaleni. Ngcono kuyobe kungakazukufika masinyane, futhi emva 3-4 umjovo.
Abanye omama bathi uma wenza imijovo ngaphambi kokudla, ungase ube isicanucanu nesiyezi. Imithi emva kokudla kungcono ikubekezelele izingane. Naphezu ukuphumelela izidakamizwa, awusebenzi ukunikeza 100% yokutakula.

Medicine "Metodzhekt": Izibuyekezo rheumatoid arthritis

Imibono ngalokhu ukulungiselela yakhiwa ikakhulukazi omuhle. Iziguli bathi umenzeli kuvimbela ukuthuthukiswa lesi sifo, kodwa, uma sisetshenziswa kufanele igcinwe ngaphansi kweso lwezokwelapha.

Medicine aqede ukuvuvukala, aqede ubuhlungu, kodwa hhayi wonke ubuhlungu iya ngokuphelele. Ezinye bephoqeleka ukuba bathathe analgesics ezengeziwe. Umuthi uyasebenza ngeviki, futhi uma isikhathi ayenzi shot, izimpawu zesifo kungenzeka futhi. Iziguli zwa impumuzo emva umjovo 5th.

Kunabantu abangazange babe ukunciphisa umthamo futhi kubhujiswe izidakamizwa okubangelwa nomthelela ongemuhle. Bona ziyabonakala uhlobo lwesifo, ubuhlungu, isiyezi kanye nesicanucanu. Laba bantu baye baphawula ukuthi umthamo kumele kancane kancane futhi kuphela ngemva kokuba ekufezeni ukuthethelelwa okuphelele.

Ziyanda iziguli esekhala iqiniso lokuthi izidakamizwa kunzima ukuthola Pharmacy futhi kufanele ngaphambilini ngokukhethekile. Abaningi kungukuthi aneliseke amanani aphezulu umuthi. Bona wazi ukuthi iziguli imithi samathambo kumele sikhishwe mahhala, njengoba akubona bonke abakwaziyo ukuthenga ke.

Ngokuvamile, ukuze kwelashwe izifo ezinzima ngisho namalungu omunye izidakamizwa ezinamandla kakhulu futhi zanamuhla "Metodzhekt". Ukubuyekezwa (nge -rheumatoid arthritis ezinganeni kanye nabantu abadala, lokhu kubalulekile ikakhulukazi) bathi kuvimbela ukuthuthukiswa isifo futhi kusiza ukuba sifinyelele ukuthethelelwa eside.