Analogs "Verapamil", yokusetshenziswa zomuthi kanye nokubuyekeza

Inhliziyo abantu yisona sakhiwo ebaluleke kakhulu. Ngakho-ke, kumelwe niyinakekele kahle kuye. Pharmacologists ekhiqizwa ezihlukahlukene izidakamizwa ukuthi silondoloze ukusebenza inhliziyo. Omunye wabo lesi sidakamizwa "Verapamil". It ezinqunyiwe ukwephula esimiso senhliziyo nemithambo yegazi, unomfutho wegazi ophakeme. Cabanga ngalokho buyisidakamizwa kuyaphumelela kakhulu kunoma iyiphi pathologies. Futhi ziyini analogue of the "Verapamil"?

Ukukhishwa

Umuthi itholakala ngezindlela ezihlukahlukene Isikali:

• amaphilisi (40 mg, 80 mg);
• isixazululo / e (2 ml / 5 mg);
• amaphilisi okuqhubekayo-release (240 mg).

Ukwakheka izidakamizwa

Just like abaningi analogue "Verapamil", umuthi iyithuluzi elihle ekwelapheni arrhythmias inhliziyo. Lesi sici kubangelwa ketshezi eziyisisekelo nomuthi. Isithako asebenzayo we umuthi verapamil hydrochloride.

Ngaphezu kwalokho iqukethe sebuningini nomuthi izinto asizayo:

• calcium phosphate dibasic;
• talc ukuhlanzwa;
• magnesium stearate;
• gelatin;
• hydroxypropyl methylcellulose;
• butylhydroxyanisole;
• indigo;
• methylparaben;
• isitashi;
• titanium dioxide.

Ngokwemvelo, analogs "Verapamil" aqukethe eyodwa isithako, izithako engeziwe zihlukile.

imiphumela kwemithi

Ngu izidakamizwa "Verapamil hydrochloride" imfundo ibonisa ukuthi izidakamizwa engena iqembu calcium channel blocker.

I nomuthi libhekene Izakhiwo ezilandelayo:

• antiarrhythmic;
• antianginal;
• antihypertensive.

Kubantu, ke wenza imisebenzi eminingana:

1. Kunciphisa isidingo inhliziyo oxygen.
2. Ithuthukisa izitsha yenhliziyo.
3. Yehlisa inani zisaphila.
4. Kuyasiza ukunciphisa contractility esivimba amanzi.
5. Kunciphisa ithoni imisipha bushelelezi kwemithambo.
6. Kuthuthukisa yenhliziyo ukugeleza kwegazi.
7. Kuhaya nokucindezela automaticity itheku engeyokuqala.
8. Siyehla AV-conduction.

Kuyinto ngenxa lo mphumela kwemithi, odokotela bavame akunikeze imithi ukuze 'verapamil' iziguli. Analogs zomuthi nemiphumela efanayo emzimbeni. Kodwa ubuyisela luhlobo yokuqala kuphela is hhayi Kunconywa.

izinkomba ngoba

Lapho ukwephula ukusebenza uhlelo senhliziyo nemithambo yegazi uncoma ukusetshenziswa kwezidakamizwa "Verapamil" imfundo manual. Analogs izimali zivame lomisiwe pathologies efanayo. Nokho, odokotela abaningi bakhetha zihlanganisa indlela yokuyelapha umuthi yasekuqaleni.

I imithi esetshenziselwa ukwenza umuthi. Lokhu kungase ezosetshenziswa prophylaxis of pathologies izidakamizwa "Verapamil".

Izinkomba ukusetshenziswa:

• angina (ezinzile, engazinzile);
• normal inhliziyo isigqi;
• arrhythmias supraventricular;
• Prinzmetal angina ;
• flutter atrial, fibrillation atrial;
• angina okufana;
• supraventricular tachycardia paroxysmal;
• nomfutho wegazi ophezulu.

Kodwa-ke kufanele wakhumbula ukuthi iyiphi imithi kuthinta umzimba ngamunye. Ngakho-ke liqoke zokuzelapha akudingekile "Verapamil". Izinkomba ukusetshenziswa - lokhu akulona umhlahlandlela esenzweni. Nikeza imithi kufanele kudokotela.

Izimo

Kunconywa ukuba ekuqaleni ufunde imiyalelo emuthini "Verapamil hydrochloride". Analogs futhi izindlela zokuqala babe Izimo. Yingakho noyedwa imithi kumele kusetshenziswe awuwedwa.

Cabanga ngaphansi kwaziphi izimo kanye pathologies ithuluzi ezingalimaza umuntu.

I Izimo eziyinhloko ukusetshenziswa kwezidakamizwa yilezi:

• ukuzwela Ephakeme isiguli izingxenye eziqukethwe ukulungiselela;
• ukumelwa inhliziyo, ogeleza ifomu okungamahlalakhona, isinyathelo 2b-3;
• ukushaqeka cardiogenic (okuhlukile yisimo kubangelwa arrhythmia);
• isilethikusebenza;
• ogulayo itheku syndrome;
• syndromes: Morgagni-Adams-Stokes, Wolff-Parkinson-White syndrome;
• AV-block 2 no-3 degrees;
• sokukhulelwa (1 yokuthathu);
• ukuhluleka kwenhliziyo ngefomu acute;
• lactation;
• block sinoatrial ;
• ekuphathweni emthanjeni we-beta-blocker;
• bradycardia.

Ngaphezu kwalokho, izidakamizwa ayenzelwanga izingane ezingaphansi kweminyaka engu-18 ubudala.

Lapho imithi kufanele kwenziwe ngokukhulu ukucophelela?

Kwezinye pathologies, udokotela angase akunikeze imithi. Nokho, indlela yakhe idinga ngokuqaphelisisa kwesimiso lesiguli. Uma kwenzeka nemiphumela engemihle udokotela ngokushesha esikhundleni amaphilisi "Verapamil". Analogs ukuthi uzobe Kunconywa ukuba isiguli ukuhlinzeka ukwelashwa ezidingekayo, futhi musa avuse imihlola engathandeki.

Ngokusho imiyalelo kanye nokusetshenziswa ukunakekelwa okukhulu kusho pathologies ezilandelayo:

• ukumelwa inhliziyo, ogeleza ifomu okungamahlalakhona (1, 2 degrees);
• bradycardia;
• AV-ukuvinjelwa (I degree kuphela);
• hypotension ;
• uzwakalise yokuphazamiseka ukusebenza isibindi.

Isikali ithebhulethi izindlela

Kunconywa ukuthatha amaphilisi ngesikhathi ukudla noma ngokushesha ngemva kokudla. iphilisi ngalinye kufanele kugwinywe ngamanzi.

Ngokusho imiyalelo, iziguli ukuthatha izidakamizwa "Verapamil" kufanele ihambisane nemithetho elandelayo:

1. Ukuze angina kanye arrhythmia zokuvimbela imithi uqhutshwa izikhathi 4 ngosuku 80 mg.
2. Uma izinga akhethiwe engalethi le oyifunayo nomphumela oqabulayo, udokotela imithi isiguli umthamo enkulu. Kulokhu, ukusetshenziswa 160 mg.
3. Kubalulekile ukukhumbula ukuthi izinga nsuku zonke saleli umuthi 480 mg.
4. Uma isiguli uye kahle ukusebenza isibindi excretion kancane imithi, ukwelashwa ithoma nge umthamo ephansi. Ngakho, umthamo nsuku zonke mg 120.

isixazululo Isicelo

Leli fomu zomuthi iqondiswa amaconsi kuphela. Nokho, kuleli cala, nakuba izidakamizwa kuyafaneleka ngokuphelele "Verapamil" izinkomba ukusetshenziswa zokukhwabanisa enjalo kufanele ngempela zingalawulwa.

Ikhambi Ngaleso kancane injected. Kulokhu, isiguli sihlale njalo siqaphele cardiogram, inhliziyo nomfutho wegazi lazo wawungcono.

Endabeni paroxysmal pathologies esigulini abanomfutho wegazi ophakeme crisis iqondiswa 5-10 mg izidakamizwa. Phakathi isigamu sehora isimo lesiguli ngcono kakhulu. Uma senza okufanayo is hhayi waphawula, inqubo iyaphindwa.

side effects

Kumele kuthathwe kuphela kadokotela umthamo zomuthi esabelwe 'Verapamil ". Izibuyekezo abonisa: yimuphi ukuphambuka kusuka imithetho kungabangela ukusabela engadingeki.

Umuthi has ohlangothini imiphumela elandelayo:

1. Inhliziyo nempahla. Kungase kube bradycardia, AV-block, hypotension. Ezinye iziguli ukuzwa ububomvu ebusweni. Ngezinye ebulilini beba nezimpawu ephethwe yisifo senhliziyo.
2. CNS. ukukhathala yanda, ukucasuka sezinzwa, kuphakama wezakhiwo. Ngezinye izikhathi abantu bazizwa ukucobeka, isiyezi.
3. Isimiso sokugaya ukudla bungene. Kwangathi ukuzwa isicanucanu, ukuhlanza, futhi ukuqunjelwa. Kwezinye izimo, kwakukhona ukwanda enzyme isibindi.
4. ukubonakaliswa nomzimba. Okungenzeka izidakamizwa ukusabela ezifana ukulunywa, ukuqubuka kwesikhumba.

Ngakho kubalulekile ukwazi ukuthi le miphumela emibi iholela izidakamizwa 'verapamil' imfundo manual. Izibuyekezo iziguli abasebenzisa imithi enqunywe udokotela ngokuvumelana scheme, bonisa ukuthi izenzakalo ezinjalo kuyagcinwa kakhulu kuyaqabukela.

analogue imithi

Yezemithi athuthukile amathuluzi eziningi Ungashintshanisa izidakamizwa yasekuqaleni. Nokho, nhlobo ukukhetha analogue "Verapamil" ngokuzimela.

Uma uhlangabezana ezimweni ezithile (isibonelo, i-sobala side effects), futhi udinga ukuthola enye indlela, qiniseka ubuze udokotela wakho. Lesi seluleko esilula uyosindisa emiphumeleni impatho engafanele.

Ngakho, cabanga ngalokho ku izidakamizwa "Verapamil" omqondofana, anomqondo ofanayo:

• "Verakard".
• "Verapamil Sopharma".
• "Vero verapamil."
• "Isoptin".
• "Verapamil Mival".
• "Verogalid EP".
• "Isoptin SR 240".
• "Verapamil-Eskom."
• "Lekoptin".
• "Verapamil Ratiopharm".
• "Kaveri".
• "Verapamil Lect."
• "Finoptinum".

Izixwayiso

Phakathi imithi "Verapamil" kufanele ucabangele okulandelayo:

1. Zonke iziguli kudingeka ukuqapha umsebenzi senhliziyo izinhlelo zokuphefumula. Qiniseka ukuqapha ezingeni glucose futhi electrolyte egazini, ivolumu umchamo.
2. Ukusetshenziswa 6 g zomuthi kungabangela nokulahlekelwa ukwazi, umfutho wegazi ophakeme, itheku bradycardia, asystole. Ezimweni ezinjalo, isiguli zidinga ukwelashwa lingaze.
3. Ingxube nomuthi nge ephefumula imithi yokubulala izinzwa, antiarrhythmics, β-blocker kuholele anda umphumela cardiotoxic.
4. izidakamizwa Antihypertensive futhi isisu ukuthuthukisa umphumela hypotensive zomuthi.
5. Phenobarbital nemithi "rifampicin" buthaka ukuphumelela izidakamizwa "Verapamil".
6. Izidakamizwa "Lithium" futhi "carbamazepine", ngenkathi ukusetshenziswa izindlela ngenhla, kwandisa ingozi yokungenwa ukubonakaliswa Neurotoxic.
7. Nge inhlanganisela yemithi "Verapamil" futhi "Digoxin" Kumele alawulwe okuqukethwe igazi zomuthi yokugcina. Njengoba ingozi eliphezulu lokudakwa amenze.
8. I nomuthi njengoba sisetshenziswa ndawonye imisipha relaxants kungase kwandise umthelela wale mithandazo.
9. Amalungiselelo "Ranitidine", "cimetidine" neqhaza ukuphakamisa lokuhlushwa asebenzayo izidakamizwa izidakamizwa "Verapamil lokuthoma" ngaphakathi kweengazi.
10. Inhlanganisela lokhu kusho ne nomuthi "Acetylsalicylic acid" kungaholela ukopha.
11. Ingqikithi asebenzayo uyakwazi ligqame ubisi lwebele. Ngakho-ke kuyinto efiselekayo kakhulu ukusebenzisa ithuluzi phakathi lactation.
12. Abesifazane abakhulelwe ebekiwe imithi kuphela lapho inzuzo izidakamizwa ukuze umama kunalelo kwabo engozini ngoba nje ukuphila nempilo ingane.

Izibuyekezo sokulungiselela

Njenganoma iyiphi imithi, ezinye iziguli leli thuluzi ibonwa njengoba imithi esindisa impilo ezingaba izimpawu ezingezinhle. Kodwa ezinye iziguli wagxeka izidakamizwa, okubonisa ukubonakaliswa ukusabela ezingezinhle.

Nokho, cishe bonke abantu ngokuthatha imithi, uyavuma entweni eyodwa: kusiza ngempela nezinkinga inhliziyo noma imithi ingcindezi "Verapamil". Nobufakazi ugcizelele izimfanelo zomuthi.

It uyakwazi kakhulu ukunciphisa izinga lokuhlasela kwesifo arrhythmias. Medicine kusiza kahle aphansi wegazi nomfutho wegazi ophezulu. Imiphumela emihle zibonakala iziguli uxilongwe angina. Abantu uhlangabezana kuzuba ubuhlungu wegazi, uqaphele ukuthi ngenxa nomuthi akwazi ukubuyela ekuphileni zemvelo, normalizing isimo salo.

Kodwa cishe zonke iziguli ukuthi izidakamizwa alethwe imiphumela ezuzisayo obubonisa ukuthi ejenti useqokwe udokotela.