"Isotretinoin": yokusetshenziswa, izinkomba, ukubuyekezwa

Ukwelashwa kwezifo ezihlukahlukene zesikhumba Kwenziwa sibonga ukwakhiwa eliqukethe e ngezithako zawo isotretinoin. Ingqikithi ubhekwa sibonga dermatoprotektivnym ezakhiweni layo eliyingqayizivele. Ukulungiswa igama elifanayo isetshenziselwa ukwelapha seborrhoea, induna. "Isotretinoin" yokusetshenziswa Kunconywa ukuba asebenzise kuphela emva kokubonisana udokotela wakho. Ngokwe-nokubuyekezwa, umenzeli liphumelele izinqubo ukuvuvukala esikhumbeni.

incazelo

Izidakamizwa "Isotretinoin" kuyinto retinoid enamandla. Lesi sakamuva kubhekisela esenzakalweni esiyisimangaliso esuselwe uvithamini A. uya izidakamizwa esebenzayo - isotretinoin - eyaziwa ngokuthi retinoic acid futhi ine uhlobo powder aphuzi. Ingqikithi uyakwazi ukululaza amaseli ngokushesha sokuhlukanisa umdlavuza. Le mpahla ekuqaleni esasisetshenziselwa ekwelapheni umdlavuza.

Ngemva kwesikhathi esithile, okuye kwatholwa abacwaningi kwesinye isakhiwo zokwelapha izidakamizwa oluyimpuphu - ke uyakwazi ukwehlisa ukukhiqizwa sebum ngu ezivimbela ukukhula ngokweqile we epithelium cell Amapayipi excretory. Le mpahla ivumela ezisetshenziswa njengamanje ekwelapheni induna ezinzima kusho "Isotretinoin".

I ukwakhiwa ezisuselwa kulesi isithako ingasetshenziswa kokubili ngaphandle futhi ngomlomo. izindlela kahle ukhetha wesikhumba sekuhloliwe isiguli.

Kanjani umuthi?

Izidakamizwa "Isotretinoin" imfundo manual uncoma ukuthi usebenzise nokwelapha induna izibazi imvelo nezinye izifo zesikhumba. Umthelela zokwelapha zomuthi ine umphumela ngesikhathi esisodwa kuzo zonke izici ezibanga lezi zifo. Okokuqala, kunciphisa ukukhiqizwa sebum, ikhule ezimbotsheni bahlanza.

retinoid lefundo kuvimbela ukukhula nezilwanyana ezincane sokugembula Propionibacterium acnes, elibangela induna, nezinduna. Relief ukuvuvukala, ukuzinza of pH - njengoba inani ukulungiswa. "Izoteretinoin" ngenkuthalo lisetshenziswe nezesikhumba kanye Cosmetology. isakhi Active ivumela ukuthonya hhayi kuphela izimpawu zesifo, kodwa futhi ukuba nazizathu ezaholela ukuthuthukiswa ukuvuvukala.

Izinkomba ukusetshenziswa

Qaphela ukuthi it is hhayi Kunconywa ukusebenzisa "Isotretinoin" ngaphandle udokotela. Inani amalungiselelo lokusebenza olungaphandle ku ngesisekelo ketshezi asebenzayo efanayo kuyahlukahluka ngaphakathi ruble 280-650. Yabela izidakamizwa e ifomu tablet ebukhoneni pathologies ezithile. Ziyakwazi:

• seborrhea;
• Rosacea (kuhlanganise ezinzima);
• Zonke izinhlobo induna;
• induna nodulocystic;
• izinhlobo ezahlukene dermatitis;
• ichthyosis azalwa nako.

Eziningi zalezi izifo yilezi imbangela obumbene imvelaphi - ngokweqile nezindlala sebaceous. Lokhu, kuholela ukuphazamiseka ezibucayi ibhalansi evamile epidermis.

Yini umphumela uzokwethula izindlela?

Ngokusho ucwaningo oluningana, ukuphumelela izidakamizwa baqiniswa ezihlukahlukene izifo zesikhumba. "Isotretinoin," iyehlisa umsebenzi nezindlala sebaceous (90%) kanye normalizes izinqubo ezenzeka esikhumbeni. Odokotela batusa ukusetshenziswa ngisho ifomu okunzima imithi induna ngefomu ithebhulethi "Roaccutane". Isotretinoin isetshenziswa nomongo esebenzayo eyinhloko.

Okukushoyo isicelo nezokusigcoba kuthiwa kungase kutholakale kahle ekwelapheni induna, Rosacea, futhi dermatitis. Lezi retinoids ingasetshenziswa imnene izifo zesikhumba ngokulinganisela. Ochwepheshe bathi izidakamizwa ngale ndlela kuphephile kakhulu ngokuba nomzimba ngaphezu amaphilisi. Lapho temlomo isotretinoin lokuhlushwa yayo igazi luyanda 2,000 ng / ml. Uma sisebenzisa amafutha, izinga ngeke idlule 60 ng / ml.

Amalungiselelo esekelwe isotretinoin

Isithako asebenzayo isotretinoin yokusetshenziswa libhekisela zemvelo retinoids. Idlanzana lezi zakhi kahle amuncwa wumzimba, nethonya elihle esikhumbeni, kunciphisa ukukhiqizwa sebum, ube isinyathelo imithi elwa nawo. Ezinye amalungiselelo zangaphandle aqukethe isotretinoin:

1. wamafutha Retinoic.
2. "Izotreksin" (gel).
3. "Retasol" (isixazululo).

Ukuze abaphathi lolukhulunywako pathologies okunzima Ochwepheshe isikhumba imithi enqunyiwe ezifana "Aknekutan", "Roaccutane", "ukusula". Ukwakheka (isotretinoin isetshenziswa njengethuba isithako), futhi umthamo zingahluka.

side effects

Lapho esingeqile Isikali isotretinoin kubangela engemihle. Kusukela ibanga zivela kaningi kakhulu amasosha omzimba. Iziguli esekhala ukuqubuka, ububomvu, uyaxebuka isikhumba neyamasundu amathe ezinyawo, ukulunywa, nail sokuwohloka amapuleti. Kungenzeka futhi ukuvela cheilitis - yisifo esithinta isikhumba phezu izindebe.

Isimiso sezinzwa okungukuthi, ezinye iziguli nazo ukuhlupheka ngenxa ekwelapheni "Isotretinoin" izidakamizwa. Izibuyekezo basikisela ukuthi kungenzeka avele ikhanda, ukukhathala kakhulu, ukuphazamiseka kwengqondo acuity ezibukwayo, ukucindezeleka ekuthuthukiseni kanye sengqondo. Abantu somoya emlandweni ukuthatha izidakamizwa kuyingozi kakhulu. Lokhu kungaholela bronchospasm. Imiphumela engemihle ezithweni umbono owabonakaliswa izimpawu ezifana keratitis, blepharitis, neuritis optic, conjunctivitis, ukuluma kwamehlo.

On the ingxenye ipheshana yesisu eba pancreatitis, uhudo, ukopha zangaphakathi, ukuhlanza, emathunjini ukuvuvukala mucosal, i-hepatitis. I-Arthritis, ubuhlungu emalungwini nemisipha, hyperostosis - izimpawu nemiphumela engemihle ka isotretinoin ku uhlelo zemisipha.

Izimo

Okokuqala, bhukwana izidakamizwa "Isotretinoin" imfundo sivimbela ukusetshenziswa ngesikhathi ekhulelwe noma ukuhlela. Ingqikithi kuyinto embryotoxic kanye nemiphumela teratogenic, okungaholela anomalies ekuthuthukisweni kanye yokuzalwa bekhubazekile ku-fetus. ochwepheshe batusa ukuqala ukuhlela sokukhulelwa ngaphambili kuka 3-4 izinyanga ngemuva kokuphela imithi yokwelapha. Phakathi nalesi sikhathi, isotretinoin amazinga emzimbeni ukuba babuyele okuvamile.

Akuvunyelwe ukuba uthathe retinoids ngesikhathi lactation, uma hypersensitivity noma ukungabekezelelani, kuhlangene le antibiotic izidakamizwa tetracycline. ekuphathweni Oral imithi contraindicated ezimweni kuphazamiseka ezinzima kwesibindi nezinso ngezinye lipids zandiswe serum igazi komdlavuza. Ezigulini ezine-hypervitaminosis A ubuye isotretinoin asihambisani.

Intengo imikhiqizo eshibhe esekelwe yalolu ketshezi - ruble 280-350. Ukwelashwa lwemithi, umthamo, analogs ukhetha udokotela kuphela.

Indlela?

Isotretinoin kwenziwa ngendlela amaphilisi kwezokuphatha ngomlomo kufanele uphuze ngesikhathi sakusihlwa. Umthamo kokuqala uqobo esingaphansi kuka 0.1 mg amakhilogramu esisindo isiguli ngasinye. Ngemva kwalokho umthamo kungase kukhule (uma Dynamics omuhle kanye nokuntuleka side effects).

Isilinganiso umthamo wansuku zonke (0.5 g) kufanele ihlukaniswe izigaba eziningana. Kuye kobukhulu ukugula kungase kwandise. Khumbula ukuthi usuku kungathatha elingekho ngaphezu kuka 10 amagremu isotretinoin. imithi ngokuvamile eside, amasonto 16-24. Isikhawu phakathi izifundo yokwelapha kumele kube okungenani izinyanga ezimbili.

Izidakamizwa "Roaccutane"

Inani nomuthi sezingeni eliphezulu futhi oda ruble 2700 iphakheji (20 mg umthamo). Umkhiqizi iyinkampani Swiss zemithi, "Hoffman-La Roche." Amaphilisi Abonayo "Roaccutane" ngempumelelo ngesikhathi induna inhlamba e ezinzima, keratosis pilaris, ichthyosis, keratoderma.

Isikhathi yokwelapha kuncike uhlobo isifo, futhi ngokuvamile amasonto 2-4. Usuku kufanele kube 0.5 mg kwakwakhe esebenzayo ngalinye 1 kg isisindo nesineke. Ngo evamile ukubekezelelana "Roaccutane" kufanele kuqale esigabeni sesibili sokwelashwa, okuyinto Uthatha amasonto angu-20. Kulokhu, udokotela kufanele iqaphe isifo Dynamics. Uma kukhona ukwehla izilonda by 70-80%, umuthi ngokuvamile kukhanselwe.

Izici isicelo

Phakathi ukwelashwa "Roaccutane" okubi kakhulu kungenzeka lesi sifo. Kulokhu-ke kuyadingeka ukunciphisa ukuba umthamo ubuncane (0.5 mg / kg). Ngokuvamile, amandla okuhambisa omuhle nehlala njalo ukuphathwa yi kungabonakala nasemkhakheni ngokusebenzisa izinyanga 1,5-2 ngemuva kokuqala ukwelashwa. Nokho, ezimweni ezinzima ke kudinga Yiqiniso eside reception "Roaccutane" izidakamizwa.

Intengo zomuthi ngesisekelo isotretinoin kuncike umthamo isithako esebenzayo. Amaphilisi ingaqukatha 10 noma 20 mg lokhu kwakwakhe. Isikali Isihloko kanye nokwelashwa zemithi izidakamizwa akufanele kusenze engemihle. ochwepheshe lezivakashi sithi 'Roaccutane' ebekezelele ngokubhekakade kahle iziguli.

Isixazululo "Retasol"

ingxenye yamanje ye-ejenti kuyinto isotretinoin. Uphenyo iziguli dermatologists uqinisekise kusebenta zokwelapha zomuthi. Active izidakamizwa ekwakhiweni iqukethe 0,025 mg e 1 ml. Isixazululo ngaphandle isinyathelo eqeda ukuvuvukala kanye Lentulo, linethonya phezu kwamaphaphu isikhumba. Ukulungiswa senzelwe lokusebenza isikhumba ohlanziwe. Ngosuku inqubo kufanele liphindwe kabili. Ubude besikhathi sokwelashwa "Retasolom" ngokuvamile 4-12 amasonto.

Akubalulekile ukusebenzisa isixazululo lihambisana namanye retinoids. Lokhu kungase kuvuse ukuthuthukiswa hypervitaminosis A. Akukona ukunquma "Retasol" tetracyclines ekwelapheni waqinisa intracranial ingozi.

Ngesimo ikhambi izidakamizwa ingasetshenziswa for ekwelapheni induna e intsha esikhulakhulile kusukela engu-11 ubudala. Kusho lidlule zokwelapha, lapho ukuphepha yayo iye kungase kutholakale. "Retasol" Luhle for isikhumba oily.

nobufakazi

Iziguli eziningi ziye zasetshenziswa ngempumelelo ekwelapheni imikhiqizo esekelwe ketshezi asebenzayo ezifana isotretinoin. Analogue le mithi kufanele bakhethe onguchwepheshe.

Ngo nje kwezinyanga ezimbalwa yokwelashwa, a retinoid zemvelo ezinamandla ikuvumela ukuba balahle induna, induna Rosacea. Okuningi ezinzima esehlaselwa isifo sesikhumba esenyanyekayo ezidinga okuphindaphindiwe course of ukwelashwa. Kuphela ezimweni ezingavamile, imiphumela emibi zenzeka, avame ukubonakala izivikeli mzimba: ukuqubuka nomzimba, ezomile dermis ububomvu. It is nhlobo ukuthatha imithi esekelwe isotretinoin phakathi ukuhlela sokukhulelwa, ethwele ingane noma lactation.