Umuthi 'pipolfen'. Yokusetshenziswa

Omunye ephumelela kunazo ejenti anti-iguliswa, evame ukusetshenziswa eminyakeni yamuva - "pipolfen". Yokusetshenziswa lapho ibhokisi lomuthi ngamunye, kungakhathaliseki ukuthi ikhiqizwa pellet noma njengoba isixazululo wezokuphatha / e / m. Dragees "Pulpofena" zifane lentil ebusweni shiny abanebala esiluhlaza, ngaphandle iphunga. Umjovo esobala, ngokuvamile kungekho nto enemibala emihle, kodwa Ngezinye izikhathi kungase tinged oluhlaza, ayinakho iphunga.

Ngenxa yokuthi iphasela ngalinye kufanele lesi sidakamizwa "imiyalelo pipolfen 'ukusetshenziswa, abantu bangafunda isenzo kwemithi zomuthi. Ingqikithi asebenzayo yalesi izidakamizwa - promethazine. Kuyinto esuselwe phenothiazine, it libhekene okusezingeni eliphezulu umsebenzi antihistamine. Promethazine ngokushesha nangempumelelo kuthinta isimiso sezinzwa esiyinhloko: has a okuyiluthayo, sine antipsychotic, antiemetic nomphumela hypothermic, kodwa futhi Usenza sizole futhi kuvimbela hiccups.

Izidakamizwa "pipolfen" akunqandi (kodwa hhayi aluqede ngokuphelele) imiphumela kubangelwa histamine, kuhlanganise ukulunywa futhi isifuba. isinyathelo Anticholinergic okubangelwa omiswe nomthelela nolwelwesi lwamafinyila we acinene futhi ngomlomo.

Isenzo promethazine antiemetic imvelo okubangelwa ukwehla excitability we-apharathasi vestibular, umphumela emaphakathi anticholinergic, ukuthulisa umsebenzi uxhaxha neqondile umphumela inhibitory izindawo ezithile we oblongata medulla.

umphumela okulalisayo zomuthi ngenxa yokuthi promethazine kuvimbela histamine-N-methyltransferase nemabhuloki central histaminergic receptor. Ngaphezu kwalokho, promethazine futhi angamuvimba acetylcholine receptor serotinovye futhi by inkanuko receptor-alpha-adrenergic, ngokungaqondile attenuate ezishukumisayo we kumiswa reticular we brainstem. umphumela Antipsychotic ka promethazine buthaka kunoMbuso phenothiazines antipsychotic, ngoba izakhiwo zabo chemical zihluke kakhulu. Kule ndaba, kanti ukuthatha izidakamizwa in umthamo therapeutically wasabela promethazine ayinayo imiphumela elimazayo ohlelweni senhliziyo nemithambo yegazi.

Njengoba unamathele izidakamizwa "Pipolphenum" imfundo on isicelo ikuvumela ukuba ubone ukuthi imiphumela emitholampilo ye izidakamizwa ziqala ukuvela ngemuva kwemizuzu engu-2 (uma izidakamizwa saphathwa intramuscularly) noma imizuzu 5 (uma iqondiswa ngemithambo yegazi). Isenzo zomuthi kuze kube nini nanini isilinganiso samahora 5, kodwa ngezinye izikhathi kungathatha amahora angu-12.

Itholakala isethi nomkhiqizo "pipolfen" imfundo kwenza kube nokwenzeka ukuba bajwayelane izinkomba ukusetshenziswa zomuthi:

- noma yikuphi kubonakaliswa izifo umzimba uxabane nawo, kuhlanganise rhinitis, urticaria, hay fever, ukugula serum, ukulunywa, angioedema, conjunctivitis;

- phakathi ukwelashwa adjuvant ukusabela anaphylactic;

- ukuhlanza noma isicanucanu izinzwa eyenga noma kokuvela ngemva kokuhlinzwa;

- esetshenziswa njengoba , sine kokuthunyelwe noma inkathi preoperative;

- ubuhlungu ukuthi kwenzeka emva kokuhlinzwa;

- ukuze aqede noma ukuvimbela isiyezi kanye nesicanucanu, okwenzeka ngesikhathi travel ezintweni zokuhamba.

Nokho, kufanele sikhumbule ukuthi kukhona contraindications lesi sidakamizwa "pipolfen". imfundo Isicelo ikuvumela ukuba sifunde ngazo ngendlela esifike ngesikhathi:

- Izimo libhekene ngaba nokucindezeleka okukhulu we CNS;

- ukuhlanza imvelaphi elingacacisiwe, okwenzeka babeyivakashela ngankathi ezinganeni;

- ukusetshenziswa ngesikhathi esisodwa utshwala, analgesics kwezidakamizwa, elele izidakamizwa;

- Ezinyangeni zokuqala ezimbili zokuphila;

- Ukukhulelwa kanye lactation;

- Ukuvalwa glaucoma.

Kwezinye izimo, uma nithatha le imithi ziba nemiphumela emibi. Ngezikhathi ezithile ngemva kokudla izidakamizwa ngokweqile "Pipolphenum" kungenzeka. Izibuyekezo zabantu kokuthatha lesi imithi kungakulethela kanjani abanye ukwaziswa okuwusizo ku Ezimweni ezinjalo.