Incazelo thiamine izidakamizwa. Yokusetshenziswa

imithi thiamine itholakala ifomu capsule noma isixazululo esicutshini. Eyesibili igama izidakamizwa - aneurine (okuqondile.). Kuyinto uvithamini ukuthi ancibilikisa emanzini. Ingqikithi ayinakho umbala. Lapho kuphekwe - libhujiswa. Thiamine akuyona oncibilikayo utshwala. Khona-ke, ine izici ukusebenza thiamine? Yokusetshenziswa likuchaza ngokuningiliziwe injongo izidakamizwa.

Imisebenzi ye-thiamine

Vitamin thiamine yaziwa nangokuthi uvithamini B1. It ulawula lokugayeka kokudla emzimbeni ka amafutha kanye carbohydrate, usimamise ukukhula kanye nokuthuthuka, ngcono inhliziyo, wokugaya ukudla bese izinhlelo sezinzwa. Njengoba omunye impahla yayo - kuyinto amanzi encibilikayo, lo vithamini ukhiqizwa yisikhumba uma hhayi imali emzimbeni futhi akusho ukubola ukuthi ayinabo yini ubuthi.

Ukuvela thiamine

Indaba iqala lapho usosayensi Christiaan Eijkman wokuqala wathola izinto ezifana amavithamini. Ngenxa yalokho yezinto kwezokwelapha, waba owathola umklomelo kaNobel. Omunye usosayensi Casimir Funk, Vitamin iyibhulogi kwakwakhe nge nitrogen irayisi bran. Vitamin njenge-ejenti eyodwa ekugcineni wakwazi ukuthola ngo-1926.

Ubunjalo bomuntu kanye amakhemikhali

solubility Cishe ngokuphelele emanzini. I acid izixazululo aqueous of lokushisa eliphezulu akuphazamisi izidakamizwa. Ingqikithi alikhali lapho ukufuthelana zikhubazekile. I-molecule siqukethe pyrimidine futhi thiazole izindandatho ezakhiwe methylene nokuxhumanisa.

Sabalalisa emzimbeni

Cabanga indlela kwasakazwa the thiamine umzimba. Iziqondiso ukuchaza pharmacokinetics zomuthi. Ngemva edabula ipheshana wokugaya ukudla izidakamizwa amuncwa umzimba futhi zehlukaniswe ama-enzyme. Khona-ke, emizuzwini engu-15, lingena egazini kakade ifomu olukhululekile. kamuva isigamu sehora ke kwasakazwa kwezicubu ahlukahlukene. Ngesimo okumsulwa, thiamine elikhona plasma, kanye ne-phosphate esters - e leukocyte futhi erythrocyte.

Njengoba amaphesenti 50% thiamine eziqukethwe imisipha striated, izitho zangaphakathi ebangela u-40% we-Vitamin. Nerve kwezicubu isibindi futhi aqukethe thiamine ngokwanele.

Tiamindifosfata - asebenzayo wali band ester, esesikhundleni thiamine. Yokusetshenziswa kubonisa ukuthi ester uhileleke ngokuqondile kule izinqubo umzimba fat kanye carbohydrate. Lokukhipha kusuka emzimbeni kwenzeka nge izinso namathumbu.

ukusetshenziswa

Ingena imithi esizosingathwa intramuscularly noma kancane ngemithambo yegazi 1 izikhathi ngosuku. Ukweqiwa Standard abadala - kusuka 25 kuya 50 mg. Isikhathi ukwelashwa kungaba isukela izinsuku ezingu-10 ukuba inyanga eyodwa.

Futhi e imithi hypovitaminosis ezingamahlalakhona esithathwayo ngomlomo 10-25 mg. I umthamo wansuku - alahlwayo noma izigaba.

Kwezinye izimo, umuthi anda thiamine umthamo? Yokusetshenziswa ngaphansi hypovitaminosis ezinzima kuyahlukahluka umthamo zonke izinsuku we mg 300.

ubufakazi

Livu pha zisebenzisa phakathi nokukhulelwa kanye lactation. Isikali ngokuvumelana oda kadokotela.

side effects

Thiamine kungabangela inombolo ukusabela engaphathekile, pruritus, urticaria, angioedema, ngezinye izikhathi ukushaqeka anaphylactic singenzeka. Phakathi imiphumela bungavami - tachycardia futhi diaphoresis.

Izimo

Okwamanje Izimo aphila nabo. Ukulungiswa thiamine ukusetshenziswa inhlukano sivimbela ukusetshenziswa ezimeni hypersensitivity, kuyilapho menopause zesifazane, lapho encephalopathy.

iziyalezo ezengeziwe

Kukhona izinkombandlela ekusetshenzisweni esebenzisa thiamine. Yokusetshenziswa hhayi Kunconywa ukuba asebenzise izidakamizwa njengendlela esikhundleni Ukudla, kuphela uma lephelele yokwelapha yokudla. Uma kokungenisa kubangela kwenqatshwa izidakamizwa (ukuhlanza ingqondo, isicanucanu, eziqhutshwa okwamanje) uvunyelwe ekuphathweni parenteral. Uma kutholakala encephalopathy Wernicke kufanele dextrose ezinikeziwe ngaphambi kokuthatha lesi imithi.