Emizimbeni ketone e umchamo - izimbangela

Ketone emizimbeni - imikhiqizo ekhethekile umzimba kwakheka isibindi. Zibizwa ngokuthi ama-emizimbeni acetone. Lezi zihlanganisa: acetoacetic, beta-hydroxybutyric acid, acetone. Lezi izinto kufanele efanayo amakhemikhali isakhiwo futhi ube interconversion komhiaba. Synthesis emizimbeni ketone esibindini kuncike ngokuqondile sendlela amandla sina kungenziwa baphazamiseka ngenxa yokwehluleka umzimba. Kwakheka ku kwesibindi, bashiya egazini ezicutshini kwezitho ahlukahlukene, lapho behileleka ekusebenziseni umjikelezo we acid tricarboxylic bona ukubola ku amanzi nesikhutha. Cases ukuthi kukhona imizimba ketone e umchamo. Izizathu lesi simanga, kanye amagugu kungenakwenzeka ukuba lokhu uphawu zichaziwe ngezansi.

Njengoba sekushiwo, Ketova umzimba nge zamanje ayikhululwa igazi kusukela kwesibindi kwezinye izitho. Nge ngokweqile ngegazi, bacabangela zihlukaniswa ngokusebenzisa ukuphefumula (kungenzeka ngisho "acetone" nephunga ngesikhathi umoya emoyeni) futhi uhlelo excretory. Ngamanye amazwi, kukhona imizimba ketone e umchamo. Kodwa zingase zihluke izizathu ukuthi ukhiqizwa ngokweqile,.

Synthesis emizimbeni ketone luyanda ngesikhathi uzilé ukudla, njalo bezuglevodistom umsoco, ukudla esiningi imikhiqizo amaprotheni, ketoacidosis oludakayo, kabusha lo alikhali zensimbi (bayahlukane tricarbonyl umjikelezo) asetshenziswe emikhiqizweni ukudla equkethe okuthiwa ketogenic amino acid. Ngu acid ketogenic acid zihlanganisa phenylalanine, tyrosine, isoleucine, leucine.

Nokho, hhayi kuphela ukudla ezithile ziba nomthelela isizukulwane lelitfutfukile emizimbeni ketone, ngenxa yalokho kungaba emizimbeni ketone e umchamo, isizathu kungenzeka ukuthi ibe ukuhlinzwa, ukukhulelwa, ukucindezeleka okukhulu ngokomzimba, ukukhiqizwa insulini ingafaneleki. Kuwufanele benaka imbangela zokugcina kungenzeka. Kuye kwaphawulwa ukuthi ukwakheka emizimbeni ketone inqwaba ikakhulukazi - okubizwa ngokuthi giperketonemiya - kwenzeka uma equlekile sikashukela.

Ephambi kwezinduna emizimbeni ketone e umchamo ngenhla evamile, umchamo Uthola "elinuka" iphunga othize. Ngokwesibonelo, isifo sikashukela umchamo at kwephunga laso elibi angase zifane apula abolile. Kufanele kube khona sakugcina emizimbeni ketone emchamweni, isilinganiso sabo - 20-50 mg / usuku. Uma noma yisiphi sezidumbu ketone umchamo idlula kuyinsakavukela khona, kungase kube eyabonisa izinqubo sokugembula emzimbeni. Inani elikhulu laba izinto umchamo libizwa ketonuria.

Ngokolwazi ngenhla okufakiwe, kubalulekile ukuba unake okukhethekile okuqukethwe okusezingeni eliphezulu zemizimba ketone e umchamo. Isizathu ketonuria kungaba ngempela okungenangozi-non-ukulimala emzimbeni. Bantwana ingenze lutho ukukhuluma zemizimba ketone e umchamo. Norma kungenzeka izingane zabo kudlulwe, ngisho nezinguquko ezincane ekudleni, ngokomzwelo nakho ukukhathala. Nokho, imbangela emizimbeni ketone umchamo kungenzeka sokugembula - isb, isifo sikashukela, imfuluwenza scarlet fever, uhudo, pancreatitis acute, imfiva, ukuntuleka kwegazi emzimbeni, isimo predkomatoznye, nezifo ezithelelwanayo angase azithole ngisho izifo engqondo kanye nezinye izifo eziningi. Ngaphandle imithetho ngenhla kubangela okweqa emizimbeni ketone e umchamo, kungaba ezingavamile yesifo azalwa naso ezifana nesifo Maple isiraphu umchamo.

Ekuqhubeni zokuhlolelwa khona ketones, isiguli ithola yi omubi, uma imizimba ketone umchamo ingeqi enhle, futhi omuhle uma umchamo amaningi ngokungadingekile. Isibalo "uphawu lokuhlanganisa" e umphumela ukuhlaziya kungase kubonise degree of ketonuria. Ngokwesibonelo, "isiphambano" - wavuma ukusabela okuhle, ezine - okuholela ukuphendula wamemezela kangangokuthi ngokuqinisekile kubonisa khona isifo esiyingozi.

Imiphumela yokuhlaziya phezu ketonuria angeke zibonisa ngokucacile ubulwelwe isiguli. Ngisho khona eliphakeme zemizimba ketone umchamo akusho ngaso sonke isikhathi kubonise ukuthi kukhona usongo olukhulu empilweni. Noma kunjalo, kungase kube inkomba eqhubeka ehlola isimo jikelele.