Analogs "Coraxan": incazelo kanye yokusetshenziswa

Yiziphi analogue of the "Coraxan"? Impendulo yalo mbuzo kungatholakala izinto kwalesi sihloko. Ngaphezu kwalokho, sizobe ukwethula ulwazi ngalokho okudingekayo umuthi ezifana kufanele kube nokunye.

Imininingwane kawonkewonke mayelana nomkhiqizo okwelapha

Tablets "Coraxan" zimelela umuthi siyehla ukushaya kwenhliziyo. Lokhu nomuthi iqukethe ukubunjwa yayo imfuyo asebenzayo ezifana ivabradine hydrochloride, kanye izingxenye asizayo njengoba monohydrate lactose, magnesium stearate, corn isitashi, maltodextrin, futhi colloidal Silicon dioxide.

imiphumela kwemithi

Analogs "Coraxan", wathi ukulungiselela uqobo alawule kwenhliziyo ngenxa sokukhohlwa ethize itheku node ezivimbela UMA iziteshi, okuyinto futhi ilawula nokuguqulwa depolarization diastolic. isithako ye-ejenti kuyalithinta atrio-ventricular futhi izindlela intraventricular, kanye ventricular repolarization futhi contractility esivimba amanzi.

Ngaphezu kwalokho, ivabradine hydrochloride ongahlanganyela iziteshi zabo-retina, efana inhliziyo UMA-iziteshi, kuhileleke nezinye izinkinga okuyinto e okuvela ushintsho yesikhashana okuqonda sibonwa. Nokho, isici esiyinhloko agent kwemithi kuyinto deceleration ikhono kwenhliziyo.

Izinkomba ejenti ezenza imithi

Kungani ukusetshenziswa analogue "Coraxan" futhi amelwe esebenzisa ngokwayo? Le mithi kuyabekwa kulezi zimo ezilandelayo:

• angina Esitebeleni. Ukwelashwa yalesi sifo ngosizo leli thuluzi wenziwa in iziguli evamile itheku isigqi ebukhoneni Izimo noma ukungabekezelelani ukuze beta-blocker, kanye lihambisana kubo.
• ukuhluleka Inhliziyo (zezifo ezingelapheki). Nale ukwenqaba ukulungiselela uqobo kanye analogue "Coraxan" lisetshenziswa ukunciphisa izinga lokuhlasela kwesifo yezinkinga zenhliziyo. Phela, iningi ke ngokwempilo yangenyama ezihlobene in iziguli izifo ezinjalo.

Izimo ukusetshenziswa kwezidakamizwa "Coraxan"

Izidakamizwa analogue "Coraxan" futhi waletha imithi akufanele isetshenziswe kulezi zimo ezilandelayo:

• hypersensitivity kuya ivabradine hydrochloride, noma asizayo izingxenye ejenti;
• angina engazinzile ;
• ukushaqeka cardiogenic;
• bradycardia (isb ngesikhathi imvamisa Kufinyeta senhliziyo, lapho esephumule, beats angaphansi kuka-60 ngomzuzu);
• isilethikusebenza (acute);
• ukuhluleka hepatic (esibi kakhulu);
• hypotension okukhulu (blood pressure omncane 90 mmHg futhi diastolic - ngaphansi kuka-50 mm HG ....);
• itheku;
• khona pacemaker;
• block sinoatrial;
• Nokukhulelwa kanye lactation;
• block atrioventricular 3 degrees;
• ukusetshenziswa ngesikhathi esifanayo inhibitor elinamandla cytochrome isoenzymes (isib izidakamizwa "ketoconazole", "Erythromycin" "Itraconazole" "Josamycin" "Clarithromycin," "Ritonavir", "telithromycin" "Nefazodone" futhi "Nelfinavir");
• esewusana (lokuphepha nokusebenza ngempumelelo yaleli ikhambi kuze kube engu-18 ubudala engakaze wafunda);
• zokungezwani ne-lactose.

Ithathwe ngokucophelela okukhulu!

Nomuthi "Coraxan" (intengo, analogs izimali zizonikezwa ngezansi) kumele sisetshenziswe kuphela kadokotela. Ngokucophelela okukhulu, izibhebhe ezinjalo kufanele zithathwe nge:

• yokwehluleka kwesibindi (esiphakathi nendawo);
• ayewukela qt (azalwa naso) isikhawu;
• ukwehluleka kwezinso (esibi kakhulu);
• ekuphathweni kanyekanye izidakamizwa ukuthi isikhathi qt isikhawu;
• Ukusetshenziswa ngesikhathi esisodwa ubhamubhamu ijusi cytochrome isoenzymes inhibitor;
• ukwephulwa asymptomatic umsebenzi ventricular kwesokunxele;
• block atrioventricular degree 2nd;
• unhlangothi (muva kuthuthwe);
• lesikhumba ngwengwzi (ukonakala yayo);
• hypotension;
• ukuphatha ngesikhathi esisodwa-calcium channel blocker (isb, indlela "Diltiazem" noma "Verapamil").

Izidakamizwa "Coraxan": yokusetshenziswa

Analogs izindlela lokucabanga kakhulu le imithamo efanayo nezindlela kokusebenzisa ukuthi nomuthi okuthiwa. Kodwa ngaphambi kokuba uwasebenzise, qiniseka ukuba uzijwayeze imiyalelo elalifike kudokotela.

• Nge angina esitebeleni izidakamizwa esebenzayo ku umthamo kokuqala iqondiswa e isamba 10 mg ngosuku. Uma emva 3-4 amasonto, umphumela zokwelapha lwenzeke, umthamo wansuku zonke kufanele senyukela 15 mg ngosuku.
• Ngo ezingamahlalakhona senhliziyo ejenti anjalo esikhathini umthamo kokuqala iqondiswa e isamba 10 mg ngosuku. Uma emva 2-amasonto of nomphumela oqabulayo futhi akezi, umthamo wansuku zonke kufanele senyukela 15 mg ngosuku.
• Ezigulini abaneminyaka engu-75 Kunconywa umthamo kokuqala 2.5 mg kabili ngelanga. Esikhathini esizayo, ungakwazi ukwandisa umthamo izidakamizwa.
• Lapho umsebenzi kwezinso in iziguli iqondiswa izidakamizwa "Coraxan" e isamba 10 mg ngosuku. Uma emva 3-4 amasonto, umphumela zokwelapha lwenzeke, umthamo wansuku zonke kufanele senyukela 15 mg ngosuku.
• Uma normal isibindi umsebenzi in iziguli iqondiswa izidakamizwa "Coraxan" e isamba 10 mg ngosuku. Uma emva 3-4 amasonto, umphumela zokwelapha lwenzeke, umthamo wansuku zonke kufanele senyukela 15 mg ngosuku.

Imiphumela engemihle engase ibe ngemuva kokuthatha izidakamizwa

Nakuba ngempumelelo, hhayi wonke umuntu nezinkinga inhliziyo ezisheshayo athathe izidakamizwa. Okokuqala, lokhu kungenxa yokuthi lowo has a lot of side effects:

• angaboni kahle futhi njalo izinguquko photoreception (noma okuthiwa photopsia).
• Bradycardia, itheku arrhythmia, arrythmia ventricular, angina (engazinzile), palpitations, isilethikusebenza, hypotension, extrasystoles supraventricular, fibrillation atrial, tachycardia ventricular, futhi ischemia esivimba amanzi.
• Nohudo, ukucanuzela kwenhliziyo kanye ukuqunjelwa.
• Ukuphathwa yikhanda (ikakhulukazi ngenyanga yokuqala ukwelashwa), isiyezi, iphika, imisipha amajaqamba, inzululwane futhi nakwisyncope.
• Hyperuricemia futhi eosinophilia.
• Ukuqubuka kwesikhumba, ukukhishwa angioedema, pruritus, urticaria futhi erythema.
• Asthenia, ukucobeka nokukhathala.

Izidakamizwa "Coraxan": ukubuyekezwa, izidakamizwa analogue

Labo cha sebenzisa ithuluzi futhi, ukukhuluma ngayo ubuhle bodwa kuyo. Nokho, lokhu izidakamizwa eqolo. Ngakho, i-56 amaphilisi nemithi "Coraxan" kuzodingeka akhokhe ruble Russian mayelana 1,200. Kule ndaba, iningi iziguli isifo senhliziyo ngokuvamile baqala ukuthola analog eshibhile zomuthi.

I analogue isakhi leli thuluzi ukuze ejenti asebenzayo zihlanganisa imithi ezilandelayo:

• "Ivabradine hydrochloride";
• "Ivabradine".

Ngokwe nomphumela oqabulayo (izidakamizwa eyenzelwe ekwelapheni angina)

• "Amlodipine";
• "Asparkam";
• "Atenolol";
• "Aspirin Cardio";
• "Betalok";
• "Validol";
• "Hypoxen";
• "Izoket";
• "Diltiazem";
• "Izolong";
• "Carvedilol";
• "Concor";
• "Korvitol";
• "Lokren";
• "Cordipin";
• "Kuthiye Corinfar";
• "Metoprolol";
• "Mildronat";
• "Monosan";
• "Nitroglycerin";
• "Papaverine";
• "Nitrong";
• "Nifedipine";
• "Normodipin";
• "Plavix";
• "Prestancia";
• "Stamlo";
• "Sustonit";
• "Trimetazidine";
• "Tenoks";
• "Egilok";
• "Efoksa Long" kanjalonjalo.