Amaphilisi Antihypertensive "enkabazwe"

Tablets "yenkabazwe" ehlangana ejenti antihypertensive, ukusetshenziswa okuyinto enomthelela ukuncipha komfutho wegazi, ukumelana Imininingwane semithambo kanye Layisha. Ngesisekelo le ukulungiselela kwehle lokuhlala angiotensin II futhi aldosterone plasma, kanye okwandisa Inkomba vasodilator bradykinin. Ngaphezu kwalokho, le ndlela elihlangene kuvimbela ukungena calcium ion ku bushelelezi imisipha amaseli imithambo yegazi kanye myocardium ngenxa okusithiyayo okuthiwa iziteshi calcium. Ukunciphisa afterload phezu kwenhliziyo kanye ukunwetshwa arteriole nokuvaleka kwemithambo ye-peripheral-uhlobo ihlinzeka izidakamizwa ezifanayo, "enkabazwe". Tablets, intengo zazo yisilinganiso ruble 450, futhi baye babonisa ukuthi umphumela antianginal.

Ngokuphathelene yokwakheka ejenti antihypertensive, e esebenzayo (lamanje) izingxenye liqukethe lisinopril dihydrate futhi amlodipine besylate. Ekhuluma ewukuhlakanipha okwenziwe izinto ezengeziwe isinyathelo sodium isitashi glycolate, magnesium stearate, microcrystalline cellulose, 101 no-12.

Inkomba esemqoka yalo mkhiqizo inhlanganisela, ezifana amaphilisi, "enkabazwe", kuyinto nomfutho wegazi ophezulu ebalulekile. Njengoba contraindications aphume ashone angioedema, angioedema noma lezinceku uhlobo diopaticheskogo, ukushaqeka cardiogenic, isilethikusebenza, ukusabela iguliswa amlodipine besylate noma lisinopril dihydrate. Ngaphezu kwalokho, musa ukusebenzisa lolu ejenti anti-abanomfutho wegazi ophakeme ngoba hypotension, hemodynamically stenosis abalulekile valve yomthambo i-aorta noma mitral, angina engazinzile, ukuhluleka kwenhliziyo futhi zenhliziyo hypertrophic. Amaphilisi ku ingcindezi "enkabazwe" akunconyelwe iziguli ezingane futhi omama abakhulelwe kanye lactating.

Nge-ejenti ukunakekelwa okukhulu lisetshenziswe kweyesi azotemia, isifo senhliziyo, bradycardia, esingamahlalakhona senhliziyo, tachycardia, isifo cerebrovascular, stenosis mitral, hyperaldosteronism eyinhloko, hyperkalemia, stenosis yomthambo i-aorta, ukuphazamiseka izinso kanye kwesibindi, isifo sikashukela kanye lupus erythematosus.

Kufanele futhi ishiwo kungenzeka ukusabela ezingezinhle ezihambisana nokusetshenziswa wokulungiselela kuhlanganiswe. Ngokwesibonelo, i-tablet, "enkabazwe" kungaba liyochukuluza ikhanda elibuhlungu, ukozela, isiyezi, isicanucanu, uhudo, isifuba esomile nokuhlanza. Ngaphezu kwalokho, kungabonakala nasemkhakheni agranulocytosis, hypotension orthostatic, izinkinga zokulala, angioneurotic edema ebusweni, hyperkalemia, imizwa yethu ishintshashintsha, bronchospasm, ukuphazamiseka visual, dyspnea, rhinitis, gynecomastia, alveolitis iguliswa, tinnitus futhi nocturia. Arthralgia, ukuqubuka, ukulunywa, lomkhuba Raynaud sika, liqhaqhazela, myalgia, ukukhathala, paresthesias, asthenia, dyspepsia, futhi hyperesthesia kungabuye cuphuluza yokwelapha, lapho isihlalo main ugajwe amaphilisi "yenkabazwe".