Umuthi "L-thyroxine". Izibuyekezo Ochwepheshe. imfundo

Nomuthi "L-thyroxine" ukubunjwa yayo has levothyroxine, ngenxa yesenzo efanayo yegilo endogenous hormone womuntu. Ingqikithi, kanye emzimbeni, akheka ukuze liothyronine. Futhi, yena, engena phakathi amaseli, ulawula ukuthuthukiswa yabo kunemtselela umzimba. Umuthi "L-thyroxine" asakwazi ukwenza kule mitochondria, umzimba oxidative, alawule ngokukhetha ngaphandle amaseli bese ngaphakathi ukugeleza cations. Umthamo elincane levothyroxine ukhiqiza umphumela Anabolic, futhi phakathi - ogxile ku amaseli izicubu. Umuthi kumqhubezela phezu CNS, ngesivinini ukugaya kanye exchange of carbohydrate, amafutha, amaphrotheni.

Izinkomba ngoba ukusetshenziswa kwezimali "L-thyroxine"

Izibuyekezo Ochwepheshe mayelana izidakamizwa omuhle kakhulu. Akunikeze imithi yokwelapha esikhundleni esimweni i-hypothyroidism. Lapho lesi simo ungase ube omsakazo ezahlukene. Ngakho, nomuthi isetshenziswa eyinhloko, i-hypothyroidism yesibili, ngemva kokusebenza indlala yegilo noma ukwelashwa iodine enemisebe, nge myxedema, ukukhuluphala, ephelezelwa izimpawu ka-hypothyroidism, Cerebro-hypophyseal pathologies cretinism. Ngaphezu kwalokho, lesi sidakamizwa "L-thyroxine" (ukubuyekezwa odokotela ukhuluma ngani ukusebenza kahle eliphezulu imithi) isetshenziswa monotherapy ngoba ekubhebhetselisa goiter euthyroid, Hyperplasia euthyroid we indlala yegilo. Futhi, usebenzisa ukuphathwa izidakamizwa akhiqizwa umahluko kakhulu yegilo abulalayo ama-hormone engaphansi izimila, kuhlanganise follicular futhi papillary carcinoma.

Khipha ifomu kanye nokwakheka

Iyatholakala imithi amaphilisi ebiyelwe amabhamuza. Omunye iyunithi izindlela lingaba nalokhu isithako - levothyroxine sodium - e isamba esingu-25, 50, 100 mcg. Isibalo izithako asizayo zihlanganisa i-lactose.

Indlela yokusebenzisa izidakamizwa "L-thyroxine"

Izibuyekezo odokotela ukubonisa ukubaluleka nokulandela imiyalo umzila yokuphathwa zomuthi. Zonke umthamo wansuku zonke kumele iphuzwe ngesikhathi, okungcono - ekuseni, isigamu sehora ngaphambi kokudla. ukugwinya Ngakho ithebhulethi kumele, eliningi eyanele ngamanzi. Ukuba izinsana izidakamizwa ziyacolwa, bese ziyoncibilika esincane amanzi ukwakha ukumiswa. Ingxube wafakwa ingane avunyelwe isigamu sehora ngaphambi ekuseni yokudla wokuqala (kudingekile ukulungisa ukumiswa ngokushesha ngaphambi idili). Umthamo zomuthi, "L-thyroxine" izimpendulo wezazi okuyinto ezimweni eziningi zinhle, kwenqatshelwe eyolanda bebodwa. Ukufaka kumele udokotela ngekuya yobudala, uhlamvu zokugula, isisindo, isimo sokusebenza we indlala yegilo, njengoba kulinganiswe imingcele laboratory. Kubantu abadala, kutuswa umthamo kokuqala 25-100 micrograms ngosuku, izingane - 12.5-50 .mu.g. Khona-ke kancane kancane (25-50 mg njalo emavikini 2-3), kuze umthamo yesondlo.

Kusho "L-thyroxine": side effects

Uma ukugcina kuboniswe imiphumela Isikali enqabayo ngemva nokuphathwa izidakamizwa akusho zivamise ukwenzeka. Nokho, ngezinye izikhathi kunezindlela izimpawu ezifana isifiso yanda, kahle izinso umsebenzi, iqothukile.

Izimo

Musa ukuphuza imithi, "L-thyroxine" (ukubuyekezwa odokotela ukuxwayisa ngale, kanye isiqondiso) ebukhoneni hypersensitivity ngakunye izingxenye kufakwe Ukwakheka, thyrotoxicosis, arrhythmias, angina, pericarditis, myocarditis, emva kweminyaka eyi-65.