Umuthi 'Gynestril ": yokusetshenziswa, analogs kanye nokubuyekeza

Indlela ukuthatha lesi sidakamizwa "Gynestril"? Iziyalezo usebenzisa lo muthi uzobe kuchazwe mathiriyeli lo sihloko. Kuyo, sethula izimpendulo iziguli, umuthi, izici zayo kwemithi, izinkomba kanye contraindications.

Ukwakheka, umumo

Yini izingxenye kuhlanganisa imithi "Gynestril"? Regulations olubekwe ngasekupheleni kwaleli izindlela, kuba ukuthi isithako yayo esebenzayo mifepristone. Futhi nomuthi yakhiwa izithako engeziwe ngesimo amazambane isitashi, i-lactose, microcrystalline cellulose, povidone, magnesium stearate kanye sodium carboxymethyl isitashi.

Thenga le imithi kungaba in amaphilisi, okuyinto zahlanganiswa ngo amaphakethe amakhadibhodi.

izici kwemithi imithi

Bewazi yini ukuthi umuthi "Gynestril"? Yokusetshenziswa kuzokusiza uqonde isimiso isinyathelo lokhu izidakamizwa, futhi uzokutshela ukuthi ngaphansi izinkomba ngokusetshenziswa kwalo zokwelapha.

nomuthi Okubukwe kuyinto zokwenziwa umsuka-ejenti steroid antigestagens. Kusebenta zokwelapha zomuthi ngenxa ngezithako zawo.

Phezu kokuthola mifepristone emzimbeni womuntu ke kuvimbela imiphumela ka progesterone, kodwa akusho abonise umsebenzi progestational.

Ochwepheshe uqaphele ukuphikisana zomuthi ngenxa ukuncintisana glucocorticoid ngibopha ezingeni yokwamukela.

Njengoba yaziwa, indima esemqoka kwetinhlavu lesizalo leiomyoma inikezwe hormone besifazane, ikakhulukazi progesterone. Kule ndaba, mifepristone angabelwa ukuba isiguli ukuvimba yokwamukela progesterone. Ngenxa yalokhu ukwelashwa yenzeka ukubambezeleka isimila ukukhula, kanye ukunciphisa usayizi fibroids , futhi lesizalo.

I izakhiwo pharmacokinetic zomuthi

Iziphi izici ine izidakamizwa pharmacokinetic "Gynestril"? Imiyalelo, ukubuyekezwa wazibonela odokotela bathi ngemva kokuphathwa temlomo emakamu esiphezulu izidakamizwa siyenzeka ngemizuzu engaba ngu-80. Ngaphezu kwalokho, bioavailability salo 69%.

izidakamizwa Plasma amaprotheni kubhekwe sibopha ukuthi 98% (ne-albumin futhi alpha-1 acid glycoprotein).

Ngemva esigabeni ukusatshalaliswa kwenzeka kancane ukuqedwa isigaba. Esikhathini lokuhlushwa igazi zomuthi kuyehla ngesigamu (15 futhi 72 amahora phakathi).

Ukuqedwa umuthi ngokushesha, nenkathi 18 amahora.

izinkomba

Kusukela lapho izidakamizwa "Gynestril" angabelwa? Yokusetshenziswa, ochwepheshe zangempela sincome izinkomba ezilandelayo:

• ekwelapheni lesizalo leiomyoma;
• ukukhipha izisu intrauterine kufikela kuzinsuku ezingu-42;
• lokungeniswa (noma ukushukuma) zomsebenzi (kuhlanganise at eside);
• eziphuthumayo zokuvimbela inzalo (postcoital) ngoba kungathembeki wasebenzisa umuthi, futhi esikhathini ngemva kokuya ocansini olungaphephile.

Izimo

"Gynestril" kwezidakamizwa isisu akufanele isetshenziswe lapho:

• sokukhulelwa emtholampilo ezingaqinisekisiwe;
• kuvunyelwe ukhulela ethunjini;
• sokukhulelwa esadaleka emva ukuhoxiswa hormone izindlela umuthi, noma ngokusebenzisa i umuthi intrauterine;
• sokukhulelwa emva kwezinsuku 42.

Lapho leiomyoma lokhu izidakamizwa kungavunyelwe yokunika kulezi zimo ezilandelayo:

• ukubeka at submucous myoma ISIZINDA;
• e izimila wesibeletho;
• Hyperplasia endometrial;
• uma leiomyoma Inani likhulu.

"Gynestril" Tablets ngoba lokungeniswa zomsebenzi alisetshenziswa:

• preeclampsia ezinzima;
• normal isethulo fetus;
• pre-eclampsia;
• eclampsia;
• preterm noma ngeposi eside sokukhulelwa;
• ukungalingani Usayizi fetus ikhanda nomama ukhalo;
• zokubona akubonakali kusukela ipheshana zangasese ngesikhathi sokukhulelwa.

Ingabe jikelele Izimo izidakamizwa "Gynestril"? Imiyalelo unika yalo mbuzo ngoyebo. Lezi enqabelo zihlanganisa kwale mibandela elandelayo:

• porphyria;
• ukwelashwa eside nge glucocorticoids;
• igazi kakhulu;
• kwezinso noma yokwehluleka kwesibindi (kunoma yiluphi uhlobo);
• ukwephulwa of hemostasis (ukwelashwa anticoagulant esidlule);
• extragenital izinto ngokungathí sina;
• zokugula kohlelo zesifazane yenzalo, kuyinto uhlamvu ukuvuvukala;
• hypersensitivity (kuhlanganise umlando);
• nikotinozavisimost, ikakhulukazi ngemva kweminyaka engu-35.

Ngokucophelela okukhulu uma nithatha le imithi:

• izifo yamaphaphu obstructive (uhlamvu ezingamahlalakhona);
• ukuhluleka kwenhliziyo;
• nomfutho wegazi ophezulu;
• arrhythmia;
• isifuba somoya bronchial;
• inhliziyo isigqi thuthuva.

Izidakamizwa "Gynestril": isitatimende

Ukuze ukukhipha izisu (izibuyekezo nesineke lokhu nomuthi kuzoxoxwa kancane okunye), lokhu izidakamizwa kufanele inikwe kuphela onguchwepheshe emincane. Futhi gcina ephethe izibhebhe kulokhu kuphela khona udokotela wezifo zabesifazane.

Njengoba ukusetshenziswa kwezidakamizwa "Gynestril"? Iziyalezo sokukhulelwa ekunqanyulweni uthi kubalulekile ukusebenzisa umthamo owodwa we-mg 600.

Umuthi esithathwayo phezu amahora 1-1.5 ngemva kokudla futhi wageza phansi 100 ml amanzi.

Ukuze kwandiswe kusebenta izidakamizwa may zisekela injongo 400 mg misoprostol (ngamanye amazwi, zokwenziwa prostaglandin E1).

Ngemva amaphilisi kokuthola nesineke kumele abaqondiswa obelethisayo amahora okungenani amabili. Ngemuva kwezinsuku 1.5 noma 2 eyenziwa ultrasound. Ngisho ngemva kwamasonto 1-2 ukuqhuba luhlolo emitholampilo ultrasound okuphindaphindiwe hlola amazinga igazi hCG ukuqinisekisa kwesisu.

Kuleso simo, uma izidakamizwa awazange asize (ie, ukukhulelwa uyaqhubeka), udokotela uncoma nenshisekelo cleaner utadisha (Histology) imiphumela inqubo.

Ukukhuthaza imisebenzi ejwayelekile, umuthi kanye yaphathwa a umthamo mg 200. Lokhu bakwenza ngezindlela khona udokotela wezifo zabesifazane. Ekupheleni kosuku, umthamo we imithi iyaphindwa at umthamo ofanayo.

Ngemuva kwezinsuku 2-3, ukulinganisa ukunwetshwa emgudwini wokuzala. ukunquma Ngakho kungenzeka ukusetshenziswa ngokwengeziwe "Oxytocin" noma prostaglandins.

Kepha lesizalo leiomyoma ukusetshenziswa kwezidakamizwa "Gynestril"? Umhlahlandlela lithi uma kokutshelwa ngokukhubazeka kwengane ukulungiselela ngokuvamile yaphathwa umthamo owodwa we-mg 50. Umuthi esithathwayo ngomlomo izinyanga ezintathu.

Ngokuphathelene zokuvimbela inzalo post-coital, odokotela batusa ukusetshenziswa nomuthi kubhekwe ku isamba 10 mg nokufundisa izinsuku ezintathu emuva kokuya ocansini olungaphephile (kungakhathaliseki esigabeni kokuya esikhathini). Ukuthatha amaphilisi kulesi simo kuyinto efiselekayo amahora amabili ngaphambi noma ngemva kokudla.

amacala ukweqisa izidakamizwa

Sebenzisa umuthi at umthamo angaphezu kwamabili amagremu izimbangela iyiphi nemiphumela engemihle. Uma usebenzisa ngaphezulu kwenani elithile imithi isiguli bangase bafinyelele esingamahlalakhona adrenal, okudinga ukwelashwa lingaze.

side effects

Ukuthola nomuthi "Gynestril" ngokuvamile kubangela ezifana side effects njengoba ikhanda elibuhlungu, isicanucanu, isiyezi, ukuhlanza, ukuqubuka, uhudo, amenorrhea, lohiometra zokubona, lesizalo subinvoljutcija, komzimba, emmeniopathy, ubuthakathaka, ukucindezeleka ukuvuvukala kwesibeletho futhi ezihlobene, ukungakhululeki kanye ubuhlungu esiswini. Uma uhlangabezana lezi zimpawu, qiniseka kudokotela.

izidakamizwa ekuhlanganyeleni

It is hhayi Kunconywa ukuthatha izidakamizwa "Gynestril" parallel ama-NSAID. Kufanele kuphawulwe ukuthi lihambisana glucocorticoids kuyadingeka ukwandisa umthamo, kodwa kuphela emva kokubonisana udokotela wakho.

izincomo ezithile

It is hhayi Kunconywa ukuthatha imithi njengoba umuthi njalo.

Uma usebenzisa "Gynestril" Ukukhipha isisu njalo kufanele wazise nesineke mayelana nezinye izinketho lokhu inqubo, ikakhulukazi uma ngemva kwamasonto amabili ukukhulelwa uyaqhubeka noma kukhona isisu aziphelele (sengcupheni yokukhiqiza kwezinso ku-fetus).

Inani kanye analogue izimali

Analogs "Gynestril isimiso sokuqondisa 'zomuthi kukhona imithi ezilandelayo:" Ginepriston "," Penkrofton "," Agesta "" Mifepristone "," Zhenale "," Mifolian "," Mifegin "," Mifepreks "," Miropriston ".

Inani kubhekwe izidakamizwa kuphezulu kakhulu futhi kufana ruble 5000-6000.

Uphenyo nomuthi

imibono ocacile kanye ethize emihle noma emibi mayelana "Gynestril" ukulungiselela. Nokho, iziguli eziningi kakhulu besamukela mayelana leli thuluzi. Bathi kuyaphumelela kakhulu futhi ophephile yokwamukela.

Kufanele kuphawulwe ukuthi abanye abantu, kunalokho, bavame amqaphela ukuthuthukiswa amathuba okuba nemiphumela engemihle.

Zonke lezi Izibuyekezo zisikisela ukuthi ukuthathwa le imithi kufanele kwenziwe kuphela emva kokubonisana udokotela.