Ukulungiswa kwemithi 'Flagil', imiyalelo yokusetshenziswa, izindlela zokuphatha kanye nesilinganiso

Isidakamizwa esithi "Flagil" yisisetshenziswa se-antiprotozoal antibacterial. Isidakamizwa senziwa ngendlela yezibhebhe ezimhlophe ezimhlophe. Ukwakhiwa kwalesi sidakamizwa kubandakanya i-metronidazole - into esebenzayo ebeka izici zayo eziyisisekelo, kanye nezinsiza: i- magnesium stearate, isitashi sikakolweni, i-hypromellose, i-povidone K30.

Izenzo zokwelapha "Ukufundisa i-Flagil" zibeka umsebenzi ophezulu wokulwa ne-antibacterial, indlela yokusebenza kwezidakamizwa iqukethe ukuncipha kwezinto eziphilayo zeqembu elithile le-metronidazole ngosizo lwe-proteins yokuthutha ye-intracellular, okugcina ekuholela ekufeni kwezincane ezincane. I-Metronidazole iyasebenza kakhulu kuma-parasites amaningi, leli qembu lihlanganisa i- Trichomonas vaginalis, i- Lamblia intestinalis, i-Giardia intestinalis kanye nezinye izibopho ze-anaerobes. Ayikho imisebenzi ephakeme yomuthi we-aerobes kanye nezinyunyana ezincane ze-anaerobic.

Ngokushesha ngemva kokuthatha ukumiswa okuphelele kwesidakamizwa esithi "Flagil" kubonakala, imfundo yokusetshenziswa ibonisa ukuthi isikhathi sokungenisa asithinti ukufana kwemithi. Ukugxila okuphezulu kuphawulwe emaphashini, esikhumbeni, esibindi nasezinsweni, emzimbeni we-seminal kanye ne-cerebrospinal fluid, ematheni nasezindaweni zangasese zomzimba. I-metabolization ye-metronidazole ivela ngokusebenzisa i-oxidation esibindi, isidakamizwa sidonswa kakhulu emcimbini (cishe ngo-70%), isikhathi sokuvala, kusukela ekuvunyelweni ekuhoxisweni kokugcina, ngamahora angu-12.

Phakathi kwezinkomba zokusetshenziswa kwezidakamizwa "I-Flagil" imfundo ibiza izifo ezinjalo ezithathelwanayo njenge:

I-trichomoniasis ye-urrogenital;

- Giardiasis;

- amebiasis;

I-vaginitis engacacile.

Ngokuya ngohlobo kanye nesilinganiso sokutheleleka, irejista yesilinganiso kanye nobude bokuphatha ukulungiselela "I-Flagil" incike. Amathebulethi we-2 ama-PC. Abantu abadala bathatha izikhathi ezintathu ngosuku ngesonto nge amoebiasis. Nge-giardiasis, leli gama linciphisa izinsuku ezingu-5 kumthamo wansuku zonke olingana no-1 g. I-Trichomoniasis (vaginitis, urethritis) kwabesifazane, i-urethritis emadodeni - amaphilisi amabili ezinsukwini eziyishumi.

Kwezinye izimo, ukwelashwa ngezidakamizwa zangasese ngendlela ye-suppository kunqunyelwe ukwelashwa kwezifo zika- urogenital .

Imiphumela emibi ingenza kube nzima kakhulu ukuphatha nge-Flagil, imfundo iqukethe ulwazi mayelana nokubonakaliswa okungenakwenzeka okuvela eceleni:

- I-CNS, kunesifo esibuhlungu nesizungu, ezimweni ezingavamile - ukudideka, ukuxuba, ukucabangela.

- uhlelo lokugaya ukudla, okungajwayelekile ukuthi kukhona ukunambitheka kwesisindo somlomo kanye nomlomo womlenze, isifo sohudo, ukuhlanza kanye ne-anorexia.

Amacala angabodwa we-reaction ofergic ngendlela yama-pruritus ne-urticaria ayaziwa, futhi i-leukopenia iyenzeka ngokuphathwa kakhudlwana nomuthi. Uma uyeka ukuthatha imithi, izimpawu ziphela ngokushesha.

Kumibonakaliso yokusetshenziswa kokulungiselela "I-Flagil" imfundo iyalandisa:

- hypersensitivity kuya metronidazole;

- isikhathi sokukhulelwa nokuncelisa (ngenxa yokukhululwa kwe-metronidazole ngokusebenzisa ubisi lwebele);

Phakathi kweziyalezo ezikhethekile kufanele kuqashelwe ukuqedwa kweziphuzo ezidakayo phakathi nenkathi yokwelashwa, ukulawula okuqinile phezu kwefomu legazi. Ngenxa yemiphumela emibi engase ibe yindlela yokuzondeka kanye nekhanda, akunconywa ukuphatha ngesikhathi sokuphathwa kwezidakamizwa nganoma iyiphi indlela yokuthutha.

Kuze kube manje, azikho izincomo zokwelashwa ngokudlula ngokweqile kwe-Flagil yezidakamizwa, ezimweni ezinjalo kubonakaliswa. Akuvunyelwe ukuphuza imithi ngesikhathi esifanayo nemithi equkethe i-ethanol (kanye no-utshwala), lokhu kungabangela umphumela ofana nowe-disulfiram (i-fever ekhulu, i-tachycardia nokuhlanza).

Isidakamizwa sithengiswa ngenethiwekhi yekhemisi ngokusho kwemithi kadokotela, isikhathi esiphezulu sokugcina siyiminyaka emihlanu ku-tmax 250.