Monocytes: evamile egazini abesifazane nezingane

Kusukela ekuzalweni, bese ngasiphi yobudala, indlela ulwazi locwaningo kuyinto elula kakhulu segazi. Ekuhlaziyeni igazi wembula esinye inkomba ezingeni elinye izinhlobo leukocyte - monocytes.

monocytes

Monocytes yiwona amaningi asebenzayo futhi ezinkulu egazi, okuyinto musa aqukethe zithutha futhi uhlobo amangqamuzana amhlophe egazi. Monocytes egazini niwe kuyofika emnkantsheni wethambo, lapho kudabuka khona. Kanye igazi, kuyilapho namanje beya, bona aluka izinsuku ezimbalwa, bese ufaka izicubu emzimbeni, lapho nje zibe ama-macrophage. Umsebenzi oyinhloko macrophage ukubhujiswa kanye ukumuncwa pathogenic nezilwanyana ezincane angaphandle kanye nemikhiqizo yabo umzimba, futhi izinsalela of amangqamuzana afile. Monocytes, izinga zazo ingahluka ubudala, yaziwa nangokuthi "baka-umzimba", njengoba bebizwa ukuvimbela kahle okuvela amahlule izimila. Ngaphezu kwalokho, zenza ngenkuthalo onengxenye hematopoiesis. Ngokungafani neutrophil emva abatholako izinhlayiya angaphandle kanye monocyte amaseli ngokuvamile ungafi.

Monocytes: abesifazane evamile nezingane

Bonisa inombolo ejwayelekile monocytes ku amabanga igazi 3 kuya ku-11% we lonke inani leukocyte namaphesenti ibalwa. Kudluliswa idatha kusuka inani eliphelele, sithola amaseli ngaphezulu kuka-400 ngamunye 1 ml igazi.

Izinga monocytes egazini ingane ngeminyaka yakhe zingahluka, ngakho, lapho kuzalwa isilinganiso sabo kusuka 3 kuya 12%, amaviki angu-2 amazinga monocyte ongasukuma kuya ku-15%, kuze kube unyaka owodwa kuzofundwa kuyinsakavukela - 4-10%. Esikhathini womuntu omdala njengoba ayisibalo samasosha omzimba amhlophe kugcinwa ngaphakathi 1-8%.

Ngezinye izikhathi izingane kwenzeka ukuthi monocytes, izinga zazo kuhluka 3 kuya ku-15%, bachezuke lokhu kuyinsakavukela ngokwayo ngo-10%. Ngenxa yokwethuka kuleli cala, ayikho imbangela eyodwa. Enye into, lapho ofanayo 10% lizinga monocytes kuyinto okungavamile abadala.

monocytes ephakeme ezinganeni

Phenomenon lapho monocytes igazi bayanda (sivamile izingane kusukela 3 kuya ku-15%), has igama monocytosis. Ezimweni eziningi, ezingeni lelisetulu ubufakazi izinguquko pathogenic emzimbeni - isifo esithathelwanayo. uhlelo hematopoietic iyeke ukuba sibhekane ngokuphumelelayo Amagciwane uzoyisiza uqale ukuthuthukiswa esebenzayo ye monocytes.

Ngokuvamile monocytosis kuphawulwe izifo eziningana ezifana umalaleveva, i-rheumatoid arthritis, isifo sofuba, ugcunsula kanye nabanye.

Ngo inqubo ubuthi by izinto ezihlukahlukene, njenge-phosphorus, i-nazo imakwe monocytes ephakeme. monocytes kuyinsakavukela futhi ngokuvamile zingathandeki ngezinqubo zemvelo bokuphila ezenzeka izingane, ezifana ukuphuma amazinyo lezihlahla, noma teething.

monocytes eziphakeme abesifazane

Ukwandisa ezingeni monocytes e abesifazane ihlobenenamanye izifo ezifana: izifo ezibangelwa amagciwane noma fungal, isifo sofuba, enteritis, ugcunsula noma ukwehluleka isimiso sokujikeleza kwegazi. Isikhathi esining impela, ngemva komsebenzi we zabesifazane monocytes bayanda, ngesilinganiso abesifazane okuyizinto ububanzi 1-8% we-leukocyte Imininingwane. Isizathu sokuba inkomba ukuphambuka kwabesifazane kungase kube ngisho khona isimila esibulalayo.

Monocytopenia izingane

Monotsitopeniya iyona mkhuba lapho igazi womntwana lehla monocytes. Kuvamile, kulesi simo baphambukile umnkantsha ukwehluleka, izifo sibi ezithathelwanayo noma ngaphansi ukukhathala eqinile. Monocytopenia ngangokunokwenzeka phakathi nokuhlinzwa, ngesikhathi eside yokwelapha i-hormone noma imiphumela emibi yokwelashwa ngamakhemikhali ngemva ngemisebe.

Esimeni nokwehla elibukhali monocytes egazini izingane, kubalulekile ukuba afeze ucwaningo olwengeziwe ukuze abone nokwelashwa kwaleso sifo, okwabangela monotsitopeniya.

Wehlise monocytes kwabesifazane

Izinga amangqamuzana amhlophe kubaluleke kakhulu ukulandela ngesikhathi sokukhulelwa, kusukela azalwa nayo, ngokungathi eziningi ukucindezeleka kungaholela kwegazi, ezinzima yokukhathala. Ukuncishiswa monocytes ingase futhi abonisa isifo umnkantsha.

Ngasiphi yobudala abesifazane kudingeka ubuncane njalo ezinyangeni eziyisithupha ukuthi zihlolelwe monocytes egazini, izinga kumele singeqi 10% we-leukocyte Imininingwane.

ukwelashwa

ukwelashwa monotsitopeniya kuyinto ukuqeda izimbangela ezingokwenhlalo ezibangele isifo. Ngezinye izikhathi kwanele ukwenza amanye amalungiselelo akhethekile, kodwa ngezinye izikhathi ngeke akwenze ngaphandle ukuhlinzwa.

monocytosis isifo asinazo izimpawu. Iziguli amazinga aphakeme monocyte isipiliyoni ubuthakathaka ngokweqile kanye ukukhathala, wehlise izinga lokushisa kwenzeka, okuyinto sici izifo ezihlukahlukene. Ngakho-ke waziseni monocytosis kuphela ukuhlolwa igazi. Ukwelashwa kuzoncika pathologies ukuthi iyoba isisekelo sokuthuthukiswa sifo.

Monocytes kukhona abavikeli umzimba, futhi kubalulekile uwagcine uhla kwezinkambiso kuvunyelwe. Kunconywa okungenani kanye njalo ezinyangeni eziyisithupha ukuthatha ukuhlolwa igazi.